IL37026A - Pharmaceutical preparations containing vitamin a derivatives - Google Patents
Pharmaceutical preparations containing vitamin a derivativesInfo
- Publication number
- IL37026A IL37026A IL37026A IL3702671A IL37026A IL 37026 A IL37026 A IL 37026A IL 37026 A IL37026 A IL 37026A IL 3702671 A IL3702671 A IL 3702671A IL 37026 A IL37026 A IL 37026A
- Authority
- IL
- Israel
- Prior art keywords
- vitamin
- acid
- active ingredient
- cis
- epoxy
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title claims 2
- 150000004347 all-trans-retinol derivatives Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract 8
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 claims abstract 6
- 229960005280 isotretinoin Drugs 0.000 claims abstract 6
- 238000007910 systemic administration Methods 0.000 claims abstract 2
- 239000004480 active ingredient Substances 0.000 claims 8
- 238000002360 preparation method Methods 0.000 claims 8
- 239000002253 acid Substances 0.000 claims 3
- DDGZNINTWKHRFC-WEDZBJJJSA-N (2e,4e,6e,8e)-3,7-dimethyl-9-(1,5,5-trimethyl-7-oxabicyclo[4.1.0]hept-2-en-6-yl)nona-2,4,6,8-tetraenoic acid Chemical compound C1=CCC(C)(C)C2(/C=C/C(/C)=C/C=C/C(/C)=C/C(O)=O)C1(C)O2 DDGZNINTWKHRFC-WEDZBJJJSA-N 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 125000005907 alkyl ester group Chemical group 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000007903 gelatin capsule Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 231100000252 nontoxic Toxicity 0.000 claims 1
- 230000003000 nontoxic effect Effects 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 239000011719 vitamin A Substances 0.000 claims 1
- 229940045997 vitamin a Drugs 0.000 claims 1
- -1 γ-vitamin A acid Chemical compound 0.000 claims 1
- 208000006994 Precancerous Conditions Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 208000037828 epithelial carcinoma Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH947470 | 1970-06-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL37026A0 IL37026A0 (en) | 1971-08-25 |
| IL37026A true IL37026A (en) | 1976-06-30 |
Family
ID=4352371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL37026A IL37026A (en) | 1970-06-23 | 1971-06-10 | Pharmaceutical preparations containing vitamin a derivatives |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4464394A (OSRAM) |
| CA (1) | CA967484A (OSRAM) |
| DE (1) | DE2128462C2 (OSRAM) |
| FR (1) | FR2100815B1 (OSRAM) |
| GB (1) | GB1335867A (OSRAM) |
| IE (1) | IE35391B1 (OSRAM) |
| IL (1) | IL37026A (OSRAM) |
| NL (1) | NL170921C (OSRAM) |
| ZA (1) | ZA713539B (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2843901A1 (de) * | 1978-10-07 | 1980-04-24 | Basf Ag | Mittel, enthaltend all-e- oder 13-z-7, 8-dehydro-retinsaeure |
| US4877805A (en) * | 1985-07-26 | 1989-10-31 | Kligman Albert M | Methods for treatment of sundamaged human skin with retinoids |
| US4487782A (en) * | 1982-03-26 | 1984-12-11 | Ortho Pharmaceutical Corporation | Topical treatment of non-inflammatory acne |
| US4539154A (en) * | 1983-06-15 | 1985-09-03 | Hoffmann-La Roche Inc. | Polyene compounds |
| CA1282326C (en) * | 1984-12-14 | 1991-04-02 | Paul J. Jarosz | Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient |
| US4545977A (en) * | 1985-01-11 | 1985-10-08 | G. D. Searle & Co. | Compositions and methods for treating severe acne with isotretinoin |
| US4843096A (en) * | 1985-06-26 | 1989-06-27 | Stiefel Laboratories, Inc. | Treatment of acne |
| JP2606711B2 (ja) * | 1986-07-16 | 1997-05-07 | エム． クリグマン，アルバート | 日光で損傷されたヒトの皮膚のレチノイドによる治療方法 |
| DE3853427T2 (de) * | 1987-04-06 | 1995-12-14 | Daltex Medical Sciences Inc | Behandlung gealterter haut mit oraler 13-cis-retinsäure. |
| US5075340A (en) * | 1989-05-22 | 1991-12-24 | Iowa State University Research Foundation | Retinoic acid glucuronide preparations for application to the skin |
| KR100274101B1 (ko) * | 1992-01-22 | 2000-12-15 | 프리돌린 클라우스너, 롤란드 비. 보레르 | 9-시스 레틴산을 함유하는 약제학적 조성물 |
| CZ282548B6 (cs) * | 1992-01-22 | 1997-08-13 | F. Hoffmann-La Roche Ag | Farmaceutický přípravek |
| ES2221921T3 (es) * | 1992-07-13 | 2005-01-16 | Shiseido Company, Ltd. | Composicion para preparacion dermatologica. |
| US6310046B1 (en) * | 1995-11-17 | 2001-10-30 | The United States Of America As Represented By The Secretary Of The Army | Sequestrin of Plasmodium falciparum |
| US6733779B2 (en) * | 1999-08-26 | 2004-05-11 | L. Dean Parks | Method of treating benign prostatic hyperplasia and other benign prostate conditions |
| FR2807662A1 (fr) * | 2000-04-12 | 2001-10-19 | Cll Pharma | Procede pour stabiliser la granulometrie d'un principe actif verulent disperse dans un liquide et ses applications |
| PT1318791E (pt) | 2000-09-22 | 2004-11-30 | Galephar M F | Composicao farmaceutica semi-solida de isotretinoina |
| EP1455730A4 (en) * | 2001-12-06 | 2006-01-18 | Ranbaxy Lab Ltd | NANOTEHOUS ISOTRETINOINE COMPOSITIONS |
| GB0600134D0 (en) * | 2006-01-05 | 2006-02-15 | Vernique Biotech Ltd | Use of epoxidised molecules |
| US9078925B2 (en) | 2012-06-18 | 2015-07-14 | Galephar Pharmaceutical Research, Inc. | Pharmaceutical semi-solid composition of isotretinoin |
| FR3119130A1 (fr) | 2021-01-28 | 2022-07-29 | Psa Automobiles Sa | Véhicule avec une structure de soubassement comprenant un dispositif de protection contre les chocs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB901659A (en) * | 1959-11-25 | 1962-07-25 | Carolina Julia Cornelia Vintge | Ointment for the treatment of acne vulgaris |
| CH433944A (de) * | 1962-12-17 | 1967-04-15 | Hoffmann La Roche | Präparat zur Vitaminierung von Lebens- und Futtermitteln und Verfahren zu dessen Herstellung |
| CA945068A (en) * | 1967-10-25 | 1974-04-09 | Albert M. Kligman | Composition and method of treating acne |
| PH9210A (en) * | 1969-07-04 | 1975-07-03 | W Bollag | Method for the treatment of carsinomas utilizing compositions containing vitamin a acid compounds |
-
1971
- 1971-06-01 ZA ZA713539A patent/ZA713539B/xx unknown
- 1971-06-08 DE DE2128462A patent/DE2128462C2/de not_active Expired
- 1971-06-10 IL IL37026A patent/IL37026A/en unknown
- 1971-06-21 GB GB2894871A patent/GB1335867A/en not_active Expired
- 1971-06-22 NL NLAANVRAGE7108586,A patent/NL170921C/xx not_active IP Right Cessation
- 1971-06-22 IE IE798/71A patent/IE35391B1/xx unknown
- 1971-06-23 FR FR7122860A patent/FR2100815B1/fr not_active Expired
- 1971-06-23 CA CA116,404A patent/CA967484A/en not_active Expired
-
1981
- 1981-07-15 US US06/283,585 patent/US4464394A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL170921C (nl) | 1983-01-17 |
| IE35391L (en) | 1971-12-23 |
| IL37026A0 (en) | 1971-08-25 |
| IE35391B1 (en) | 1976-02-04 |
| NL170921B (nl) | 1982-08-16 |
| DE2128462A1 (de) | 1971-12-30 |
| US4464394A (en) | 1984-08-07 |
| DE2128462C2 (de) | 1982-12-02 |
| CA967484A (en) | 1975-05-13 |
| ZA713539B (en) | 1972-02-23 |
| NL7108586A (OSRAM) | 1971-12-27 |
| FR2100815A1 (OSRAM) | 1972-03-24 |
| FR2100815B1 (OSRAM) | 1974-09-27 |
| GB1335867A (en) | 1973-10-31 |
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