IL36079A0 - 4-morpholino-thieno (3,2-d) pyrimidine derivatives,their production and pharmaceutical compositions containing them - Google Patents

4-morpholino-thieno (3,2-d) pyrimidine derivatives,their production and pharmaceutical compositions containing them

Info

Publication number
IL36079A0
IL36079A0 IL36079A IL3607971A IL36079A0 IL 36079 A0 IL36079 A0 IL 36079A0 IL 36079 A IL36079 A IL 36079A IL 3607971 A IL3607971 A IL 3607971A IL 36079 A0 IL36079 A0 IL 36079A0
Authority
IL
Israel
Prior art keywords
thieno
morpholino
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL36079A
Other languages
English (en)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702003714 external-priority patent/DE2003714C/de
Priority claimed from DE19702058086 external-priority patent/DE2058086A1/de
Priority claimed from DE19702058085 external-priority patent/DE2058085A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL36079A0 publication Critical patent/IL36079A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL36079A 1970-01-28 1971-01-27 4-morpholino-thieno (3,2-d) pyrimidine derivatives,their production and pharmaceutical compositions containing them IL36079A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19702003714 DE2003714C (de) 1970-01-28 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze
DE19702058086 DE2058086A1 (de) 1970-11-26 1970-11-26 Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung
DE19702058085 DE2058085A1 (de) 1970-11-26 1970-11-26 Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen

Publications (1)

Publication Number Publication Date
IL36079A0 true IL36079A0 (en) 1971-03-24

Family

ID=27182372

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36079A IL36079A0 (en) 1970-01-28 1971-01-27 4-morpholino-thieno (3,2-d) pyrimidine derivatives,their production and pharmaceutical compositions containing them

Country Status (9)

Country Link
US (1) US3763156A (en:Method)
AU (1) AU2468871A (en:Method)
BE (1) BE762135A (en:Method)
ES (2) ES387553A1 (en:Method)
FR (1) FR2081464B1 (en:Method)
GB (1) GB1309182A (en:Method)
IL (1) IL36079A0 (en:Method)
NL (1) NL7101043A (en:Method)
NO (1) NO129205B (en:Method)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
US5280026A (en) * 1989-05-30 1994-01-18 Smithkline Beecham Intercredit B.V. Thienopyrimidines
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
PL1874781T3 (pl) * 2006-04-19 2009-12-31 Boehringer Ingelheim Int Dihydrotienopirymidyny do leczenia chorób zapalnych
EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
CA2650290C (en) * 2006-04-26 2015-11-17 Genentech, Inc. Pharmaceutical compounds
EP2046799B1 (en) 2006-04-26 2017-07-19 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
DK2024372T3 (da) 2006-04-26 2010-09-20 Hoffmann La Roche Thieno[3,2-d]pyrimidin-derivat, der er egnet som P13K inhibitor
US7888352B2 (en) * 2006-12-07 2011-02-15 Piramed Limited Phosphoinositide 3-kinase inhibitor compounds and methods of use
ES2571028T3 (es) * 2006-12-07 2016-05-23 Genentech Inc Compuestos inhibidores de fosfoinositida 3-cinasa y métodos de uso
CN101932587A (zh) 2007-09-24 2010-12-29 吉宁特有限公司 噻唑并嘧啶pi3k抑制剂化合物及使用方法
JP5563466B2 (ja) 2007-10-19 2014-07-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規ピペラジノ−ジヒドロチエノピリミジン誘導体
CN101827853A (zh) 2007-10-19 2010-09-08 贝林格尔.英格海姆国际有限公司 杂环取代的哌嗪子基-二氢噻吩并嘧啶
DK2610258T3 (da) * 2007-10-19 2014-11-10 Boehringer Ingelheim Int Substituerede piperidindihydrothienopyrimidiner
CA2701292C (en) 2007-10-25 2015-03-24 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
US8536161B2 (en) 2009-03-12 2013-09-17 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
CN102459272B (zh) * 2009-05-27 2014-08-06 健泰科生物技术公司 对P110δ具有选择性的为PI3K抑制剂的二环嘧啶化合物和使用方法
WO2010136491A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
JP2013507415A (ja) * 2009-10-12 2013-03-04 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Ｐｉ３ｋ阻害剤とｍｅｋ阻害剤の併用
CA2793892A1 (en) 2010-04-16 2011-10-20 Elizabeth Punnoose Foxo3a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
AR094873A1 (es) 2013-02-25 2015-09-02 Genentech Inc Métodos y composiciones para detectar y tratar mutantes de akt resistentes a fármacos
MX2021003794A (es) * 2018-10-01 2021-09-08 Genzyme Corp Derivados de tieno[3,2-b]piridina como inhibidores de la udp glicosiltransferasa y metodos de uso.
GB202014736D0 (en) * 2020-09-18 2020-11-04 Imperial College Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
NO129205B (en:Method) 1974-03-11
FR2081464A1 (en:Method) 1971-12-03
AU2468871A (en) 1972-07-27
FR2081464B1 (en:Method) 1975-04-18
GB1309182A (en) 1973-03-07
NL7101043A (en:Method) 1971-07-30
ES387553A1 (es) 1974-01-16
BE762135A (fr) 1971-07-27
ES387554A1 (es) 1974-01-16
US3763156A (en) 1973-10-02

Similar Documents

Publication Publication Date Title
IL36079A0 (en) 4-morpholino-thieno (3,2-d) pyrimidine derivatives,their production and pharmaceutical compositions containing them
IL37385A0 (en) New benzyl-azoles,their production,and pharmaceutical compositions containing them
IL36018A0 (en) New 1,4-dihydropyridine derivatives,their production and pharmaceutical compositions containing them
IL36903A0 (en) New dibenzocycloheptapyrole derivatives,their production and pharmaceutical compositions containing them
IL35078A (en) 2-aminoalkylamino-thieno (3,2-d) pyrimidines and their salts,their preparation and pharmaceutical compositions containing them
IL37984A0 (en) 2,4-diamino-5-benzylpyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL37023A (en) 4-aminophenylamidines,their production and pharmaceutical compositions containing them
IL38151A (en) Triazolobenzo diazepine derivatives,their production and pharmaceutical compositions containing them
IL37252A0 (en) Pteridine derivatives,their preparation and pharmaceutical compositions containing them
IL36345A0 (en) Benzhydryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them
IL42745A0 (en) 2-amino-4 h-pyrane derivatives,their production and pharmaceutical compositions containing them
IL36917A (en) Dibenzothiepinopyrrole derivatives,their production and pharmaceutical compositions containing them
IL36951A (en) Tropan-3-ol derivatives,their production and pharmaceutical compositions containing them
IL35087A0 (en) Imidazolidinone derivatives,their production and pharmaceutical compositions containing them
IL37888A (en) 3-phenyl-2-alkoxycarbonylaminophenyl-6(7)alkoxycarbonylamino-4-quinazolone derivatives,their production and pharmaceutical compositions containing them
IL37900A0 (en) Thiazolone-(2)derivatives,their preparation,and pharmaceutical compositions containing them
IL39584A0 (en) Benzodithiapyrone derivatives,their production and pharmaceutical compositions containing them
IL36160A (en) 7-azido-5-phenyl-dihydro-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL35221A0 (en) P-aminoalkyl-benzenesulphonamide derivatives,their production and pharmaceutical compositions containing them
IL35227A0 (en) P-aminoalkyl-benzenesulphonamide derivatives,their production and pharmaceutical compositions containing them
IL36096A0 (en) 2,6-dimorpholino-pyrimido (5,4-d) pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL43431A0 (en) Phenylguanidine derivatives,their production and pharmaceutical composition containing them
IL36832A0 (en) New dibenzazepine derivatives,their production and pharmaceutical compositions containing them
IL36324A0 (en) 1,2-methylene-9beta,10alpha-steroids,their production and pharmaceutical compositions containing them
IL35224A0 (en) P-aminoalkyl-benzenesulphonamide derivatives,their production and pharmaceutical compositions containing them