|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
PT1874781E
(pt)
*
|
2006-04-19 |
2009-07-27 |
Boehringer Ingelheim Int |
Di-hidro-tienopirimidinas para o tratamento de doenças inflamatórias
|
|
RU2439074C2
(ru)
|
2006-04-26 |
2012-01-10 |
Ф. Хоффманн-Ля Рош Аг |
ПРОИЗВОДНОЕ ТИЕНО[3,2-d]ПИРИМИДИНА В КАЧЕСТВЕ ИНГИБИТОРА ФОСФАТИДИЛИНОЗИТОЛ-3-КИНАЗЫ (РI3К)
|
|
CN101511840A
(zh)
*
|
2006-04-26 |
2009-08-19 |
吉宁特有限公司 |
磷酸肌醇3-激酶抑制剂化合物及其使用方法
|
|
DK2041139T3
(da)
*
|
2006-04-26 |
2012-01-16 |
Genentech Inc |
Farmaceutiske forbindelser
|
|
RU2470936C2
(ru)
*
|
2006-12-07 |
2012-12-27 |
Дженентек, Инк. |
Соединения-ингибиторы фосфоинозитид 3-киназы и способы применения
|
|
CL2007003520A1
(es)
|
2006-12-07 |
2008-08-22 |
Piramed Ltd Genentech Inc |
Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso para el tratamiento profilactico o terapeutico del cancer.
|
|
CN101932587A
(zh)
|
2007-09-24 |
2010-12-29 |
吉宁特有限公司 |
噻唑并嘧啶pi3k抑制剂化合物及使用方法
|
|
EP2215093B1
(de)
|
2007-10-19 |
2011-12-14 |
Boehringer Ingelheim International GmbH |
Neue piperazino-dihydrothienopyrimidin-derivate
|
|
AU2008313742B2
(en)
|
2007-10-19 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
Heterocycle-substituted piperazino-dihydrothienopyrimidines
|
|
SI2610258T1
(sl)
*
|
2007-10-19 |
2014-12-31 |
Boehringer Ingelheim International Gmbh |
Substituirani piperidino-dihidrotienopirimidini
|
|
CN101909631B
(zh)
*
|
2007-10-25 |
2012-09-12 |
健泰科生物技术公司 |
制备噻吩并嘧啶化合物的方法
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
WO2010105008A2
(en)
|
2009-03-12 |
2010-09-16 |
Genentech, Inc. |
Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
|
|
WO2010136491A1
(en)
*
|
2009-05-27 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
AU2010254161A1
(en)
*
|
2009-05-27 |
2011-11-10 |
F. Hoffmann-La Roche Ag |
Bicyclic pyrimidine PI3K inhibitor compounds selective for p110 delta, and methods of use
|
|
JP2013507415A
(ja)
*
|
2009-10-12 |
2013-03-04 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Ｐｉ３ｋ阻害剤とｍｅｋ阻害剤の併用
|
|
CN103038643A
(zh)
|
2010-04-16 |
2013-04-10 |
基因泰克公司 |
作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
|
|
WO2012088254A1
(en)
|
2010-12-22 |
2012-06-28 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
RU2015140573A
(ru)
|
2013-02-25 |
2017-03-30 |
Дженентек, Инк. |
Способы и композиции для обнаружения и лечения устойчивого к лекарственным средствам мутанта акт
|
|
KR20210087033A
(ko)
*
|
2018-10-01 |
2021-07-09 |
젠자임 코포레이션 |
UDP 글리코실트랜스퍼라제 억제제로서의 티에노[3,2-b]피리딘 유도체 및 사용 방법
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|