IL317928A - New anti-CD19 antibodies - Google Patents

New anti-CD19 antibodies

Info

Publication number
IL317928A
IL317928A IL317928A IL31792824A IL317928A IL 317928 A IL317928 A IL 317928A IL 317928 A IL317928 A IL 317928A IL 31792824 A IL31792824 A IL 31792824A IL 317928 A IL317928 A IL 317928A
Authority
IL
Israel
Prior art keywords
antibody
seq
antigen
binding fragment
cell
Prior art date
Application number
IL317928A
Other languages
English (en)
Hebrew (he)
Original Assignee
Wuxi Biologics Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuxi Biologics Ireland Ltd filed Critical Wuxi Biologics Ireland Ltd
Publication of IL317928A publication Critical patent/IL317928A/en

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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/4211—CD19 or B4
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

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IL317928A 2017-09-21 2018-09-20 New anti-CD19 antibodies IL317928A (en)

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KR20210137085A (ko) 2019-03-05 2021-11-17 엔카르타, 인크. Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
CN110003334B (zh) * 2019-04-12 2023-05-09 深圳普瑞金生物药业股份有限公司 多肽、cd19单域抗体及其制备方法、核苷酸序列及试剂盒
JP2022550435A (ja) 2019-10-04 2022-12-01 ウルトラジェニックス ファーマシューティカル インコーポレイテッド 組換えａａｖの改善された治療的使用のための方法
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IL273389B1 (en) 2025-02-01
US20200289563A1 (en) 2020-09-17
JP7295098B2 (ja) 2023-06-20
AU2018336520A1 (en) 2020-03-19
IL273389A (en) 2020-05-31
TW202500591A (zh) 2025-01-01
JP2020534012A (ja) 2020-11-26
SG11202001817PA (en) 2020-03-30
BR112020005402A2 (pt) 2020-09-29
RU2020114161A (ru) 2021-10-22
CN109535253B (zh) 2022-11-04
MX2025009320A (es) 2025-09-02
TWI812645B (zh) 2023-08-21
IL273389B2 (en) 2025-06-01
CA3074524A1 (en) 2019-03-28
TW202417507A (zh) 2024-05-01
TWI878186B (zh) 2025-03-21
AU2025202830A1 (en) 2025-05-15
CN109535253A (zh) 2019-03-29
EP3684820A4 (en) 2021-05-26
CN115819588A (zh) 2023-03-21
KR102782109B1 (ko) 2025-03-19
WO2019057100A1 (en) 2019-03-28
US11497769B2 (en) 2022-11-15
AU2018336520B2 (en) 2025-03-27
TW201920281A (zh) 2019-06-01
KR20200055758A (ko) 2020-05-21
EP3684820A1 (en) 2020-07-29
KR20250042189A (ko) 2025-03-26
MX2020003093A (es) 2020-08-17

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