IL302347A - Materials and methods for binding SIGLEC-3/CD33 - Google Patents

Materials and methods for binding SIGLEC-3/CD33

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Publication number
IL302347A
IL302347A IL302347A IL30234723A IL302347A IL 302347 A IL302347 A IL 302347A IL 302347 A IL302347 A IL 302347A IL 30234723 A IL30234723 A IL 30234723A IL 302347 A IL302347 A IL 302347A
Authority
IL
Israel
Prior art keywords
seq
hcdr1
hcdr3
hcdr2
nos
Prior art date
Application number
IL302347A
Other languages
English (en)
Hebrew (he)
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of IL302347A publication Critical patent/IL302347A/en

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K51/1096Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies radioimmunotoxins, i.e. conjugates being structurally as defined in A61K51/1093, and including a radioactive nucleus for use in radiotherapeutic applications
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
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    • C07K16/2815Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
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    • C07K16/2818Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/565Complementarity determining region [CDR]
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    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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IL302347A 2020-03-13 2021-03-15 Materials and methods for binding SIGLEC-3/CD33 IL302347A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US202062989071P 2020-03-13 2020-03-13
US202062989187P 2020-03-13 2020-03-13
US202062989120P 2020-03-13 2020-03-13
US202062989230P 2020-03-13 2020-03-13
US202062989093P 2020-03-13 2020-03-13
PCT/IB2021/052121 WO2021181366A1 (en) 2020-03-13 2021-03-15 Materials and methods for binding siglec-3/cd33

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IL302347A true IL302347A (en) 2023-06-01

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