CL2022002488A1 - Materiales y métodos para la unión de siglec-3/cd33. - Google Patents

Materiales y métodos para la unión de siglec-3/cd33.

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Publication number
CL2022002488A1
CL2022002488A1 CL2022002488A CL2022002488A CL2022002488A1 CL 2022002488 A1 CL2022002488 A1 CL 2022002488A1 CL 2022002488 A CL2022002488 A CL 2022002488A CL 2022002488 A CL2022002488 A CL 2022002488A CL 2022002488 A1 CL2022002488 A1 CL 2022002488A1
Authority
CL
Chile
Prior art keywords
binding
methods
siglec
materials
antigen
Prior art date
Application number
CL2022002488A
Other languages
English (en)
Inventor
Karla R Wiehagen
Rajkumar Ganesan
Sanjaya Singh
Sathyadevi Venkataramani
Patrick John Doonan
Mehabaw Getahun Derebe
Iqbal S Grewal
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of CL2022002488A1 publication Critical patent/CL2022002488A1/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • C07K—PEPTIDES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/70503—Immunoglobulin superfamily
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    • C07K16/2815—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

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  • Seal Device For Vehicle (AREA)
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  • Hematology (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La invención proporciona dominios de unión a antígeno que se unen a la proteína CD33 del antígeno de la superficie de células mieloides que comprende los dominios de unión a antígeno que se unen a CD33, polinucleótidos que los codifican, vectores, células huésped, métodos para fabricarlos y usarlos.
CL2022002488A 2020-03-13 2022-09-12 Materiales y métodos para la unión de siglec-3/cd33. CL2022002488A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062989093P 2020-03-13 2020-03-13
US202062989120P 2020-03-13 2020-03-13
US202062989071P 2020-03-13 2020-03-13
US202062989187P 2020-03-13 2020-03-13
US202062989230P 2020-03-13 2020-03-13

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CL2022002488A1 true CL2022002488A1 (es) 2023-03-03

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CL2022002488A CL2022002488A1 (es) 2020-03-13 2022-09-12 Materiales y métodos para la unión de siglec-3/cd33.
CL2023000910A CL2023000910A1 (es) 2020-03-13 2023-03-29 Materiales y métodos para la unión de siglec-3/cd33 (divisional).
CL2023000909A CL2023000909A1 (es) 2020-03-13 2023-03-29 Materiales y métodos para la unión de siglec-3/cd33 (divisional)..
CL2023000911A CL2023000911A1 (es) 2020-03-13 2023-03-29 Materiales y métodos para la unión de siglec-3/cd33 (divisional)

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CL2023000910A CL2023000910A1 (es) 2020-03-13 2023-03-29 Materiales y métodos para la unión de siglec-3/cd33 (divisional).
CL2023000909A CL2023000909A1 (es) 2020-03-13 2023-03-29 Materiales y métodos para la unión de siglec-3/cd33 (divisional)..
CL2023000911A CL2023000911A1 (es) 2020-03-13 2023-03-29 Materiales y métodos para la unión de siglec-3/cd33 (divisional)

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US (3) US20230250171A1 (es)
EP (4) EP4233893A3 (es)
JP (1) JP2023517660A (es)
KR (4) KR20220154728A (es)
CN (1) CN115768482A (es)
AU (4) AU2021235564A1 (es)
BR (1) BR112022018176A2 (es)
CA (1) CA3171113A1 (es)
CL (4) CL2022002488A1 (es)
CO (1) CO2022013823A2 (es)
EC (1) ECSP22071278A (es)
IL (4) IL302349A (es)
JO (1) JOP20220220A1 (es)
MX (1) MX2022011320A (es)
PE (4) PE20230001A1 (es)
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TW202328193A (zh) * 2021-09-13 2023-07-16 美商健生生物科技公司 用於治療癌症的CD33 x Vδ2多特異性抗體

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