IL294886A - Liposomal irinotecan sucrose octasulfate in combination with leucovorin and 5-fluorouracil for use in treating pancreatic cancer - Google Patents
Liposomal irinotecan sucrose octasulfate in combination with leucovorin and 5-fluorouracil for use in treating pancreatic cancerInfo
- Publication number
- IL294886A IL294886A IL294886A IL29488622A IL294886A IL 294886 A IL294886 A IL 294886A IL 294886 A IL294886 A IL 294886A IL 29488622 A IL29488622 A IL 29488622A IL 294886 A IL294886 A IL 294886A
- Authority
- IL
- Israel
- Prior art keywords
- dose
- patients
- irinotecan
- patient
- treatment
- Prior art date
Links
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- 235000008191 folinic acid Nutrition 0.000 title claims description 101
- 239000011672 folinic acid Substances 0.000 title claims description 101
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| PCT/US2013/045495 WO2013188586A1 (en) | 2012-06-13 | 2013-06-12 | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
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| IL304631A IL304631A (en) | 2012-06-13 | 2023-07-20 | Liposomal irinotecan sucrose octasulfate in combination with leucovorin and 5-fluorouracil for use in the treatment of pancreatic cancer |
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| WO2005107712A1 (en) | 2004-05-03 | 2005-11-17 | Hermes Biosciences, Inc. | Liposomes useful for drug delivery |
| US8691231B2 (en) | 2011-06-03 | 2014-04-08 | Merrimack Pharmaceuticals, Inc. | Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies |
| AU2013202947B2 (en) | 2012-06-13 | 2016-06-02 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
| US9717724B2 (en) | 2012-06-13 | 2017-08-01 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies |
| KR102501566B1 (ko) * | 2014-01-14 | 2023-02-17 | 넥타르 테라퓨틱스 | 병용 기반 치료 방법 |
| MA39599A (fr) | 2014-05-14 | 2016-10-05 | Merrimack Pharmaceuticals Inc | Dosage et administration d'agents thérapeutiques anti-egfr |
| EP3229802A1 (en) * | 2014-12-09 | 2017-10-18 | Ipsen Biopharm Ltd. | Treatment of breast cancer with liposomal irinotecan |
| WO2016168451A1 (en) * | 2015-04-14 | 2016-10-20 | Merrimack Pharmaceuticals, Inc. | Compositions for improving the pharmacokinetics and therapeutic index of cancer treatment |
| US11318131B2 (en) | 2015-05-18 | 2022-05-03 | Ipsen Biopharm Ltd. | Nanoliposomal irinotecan for use in treating small cell lung cancer |
| CA2992789A1 (en) | 2015-08-20 | 2017-02-23 | Ipsen Biopharm Ltd. | Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment |
| BR112018002941B1 (pt) * | 2015-08-21 | 2023-12-05 | Ipsen Biopharm Ltd | Uso de irinotecano lipossomal, oxaliplatina, leucovorina e 5- fluorouracil no tratamento de primeira linha de adenocarcinoma metastático do pâncreas |
| DK3349731T3 (da) | 2015-09-16 | 2024-01-08 | Univ Texas | Kombination af topoisomerase-i-inhibitorer med immunoterapi til behandlingen af kræft |
| RS67289B1 (sr) | 2015-10-16 | 2025-11-28 | Ipsen Biopharm Ltd | Stabilizacija farmaceutskih kompozicija kamptotecina |
| WO2017172678A1 (en) * | 2016-03-30 | 2017-10-05 | Merrimack Pharmaceuticals, Inc. | Methods for treating cancer using combination therapies comprising an oligoclonal anti-egfr antibody preparation and lipsomal irinotecan |
| SG11201809788VA (en) * | 2016-05-18 | 2018-12-28 | Ipsen Biopharm Ltd | Nanoliposomal irinotecan for use in treating small cell lung cancer |
| WO2018083470A1 (en) * | 2016-11-02 | 2018-05-11 | Ipsen Biopharm Ltd. | Treating gastric cancer using combination therapies comprising liposomal irinotecan, oxaliplatin, 5-fluoruracil (and leucovorin) |
| WO2020079692A1 (en) * | 2018-10-17 | 2020-04-23 | Biolinerx Ltd. | Treatment of metastatic pancreatic adenocarcinoma |
| WO2020148744A1 (en) * | 2019-01-17 | 2020-07-23 | Biolinerx Ltd. | Combination therapy for treatment of pancreatic cancer |
| US20220072087A1 (en) * | 2019-01-17 | 2022-03-10 | Biolinerx Ltd. | Specific combination therapy for treatment of pancreatic cancer |
| US11286344B2 (en) | 2020-01-10 | 2022-03-29 | Tyndall Formulation Services, LLC | Polymer excipients for drug delivery applications |
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