IL265479B - Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer - Google Patents

Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer

Info

Publication number
IL265479B
IL265479B IL265479A IL26547919A IL265479B IL 265479 B IL265479 B IL 265479B IL 265479 A IL265479 A IL 265479A IL 26547919 A IL26547919 A IL 26547919A IL 265479 B IL265479 B IL 265479B
Authority
IL
Israel
Prior art keywords
seq
complex
peptide
epitope
amino acid
Prior art date
Application number
IL265479A
Other languages
English (en)
Hebrew (he)
Other versions
IL265479A (en
Original Assignee
Amal Therapeutics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amal Therapeutics Sa filed Critical Amal Therapeutics Sa
Publication of IL265479A publication Critical patent/IL265479A/en
Publication of IL265479B publication Critical patent/IL265479B/en

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Genetics & Genomics (AREA)
IL265479A 2016-09-21 2017-09-21 Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer IL265479B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2016072475 2016-09-21
PCT/EP2017/073954 WO2018055060A1 (en) 2016-09-21 2017-09-21 Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer

Publications (2)

Publication Number Publication Date
IL265479A IL265479A (en) 2019-05-30
IL265479B true IL265479B (en) 2022-09-01

Family

ID=60037562

Family Applications (1)

Application Number Title Priority Date Filing Date
IL265479A IL265479B (en) 2016-09-21 2017-09-21 Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer

Country Status (15)

Country Link
US (3) US20190255165A1 (cg-RX-API-DMAC7.html)
EP (1) EP3515476B1 (cg-RX-API-DMAC7.html)
JP (1) JP7346291B2 (cg-RX-API-DMAC7.html)
KR (2) KR102879364B1 (cg-RX-API-DMAC7.html)
CN (1) CN109963585B (cg-RX-API-DMAC7.html)
AU (1) AU2017331949B2 (cg-RX-API-DMAC7.html)
CA (1) CA3031170A1 (cg-RX-API-DMAC7.html)
CL (3) CL2019000694A1 (cg-RX-API-DMAC7.html)
DK (1) DK3515476T3 (cg-RX-API-DMAC7.html)
ES (1) ES2983085T3 (cg-RX-API-DMAC7.html)
HU (1) HUE067838T2 (cg-RX-API-DMAC7.html)
IL (1) IL265479B (cg-RX-API-DMAC7.html)
MX (1) MX2019002968A (cg-RX-API-DMAC7.html)
PL (1) PL3515476T3 (cg-RX-API-DMAC7.html)
WO (1) WO2018055060A1 (cg-RX-API-DMAC7.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
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WO2016146143A1 (en) 2015-03-16 2016-09-22 Amal Therapeutics Sa Cell penetrating peptides and complexes comprising the same
CA3010779A1 (en) 2016-03-16 2017-09-21 Amal Therapeutics Sa Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for use in medicine
DK3515476T3 (da) 2016-09-21 2024-09-02 Amal Therapeutics Sa Fusion der omfatter et cellepenetrerende peptid, en multiepitop og en trl-peptidagnost til behandlingen af cancer
CN110650750A (zh) 2017-04-04 2020-01-03 阿维迪科技公司 基于肽的疫苗、其制造方法及其用于诱导免疫应答的用途
US12121573B2 (en) 2019-07-14 2024-10-22 Tianxin Wang Methods and agents including STING agonist to treat tumor
TW202028224A (zh) * 2018-09-17 2020-08-01 德商英麥提克生物技術股份有限公司 B*44限制肽在抗癌免疫治療的用途和相關方法
JP2022536695A (ja) * 2019-06-12 2022-08-18 ビオンテック ユーエス インコーポレイテッド 新抗原組成物およびその使用
CN110448689A (zh) * 2019-08-06 2019-11-15 太仓美诺恒康生物技术有限公司 mRNA疫苗及其试剂盒、应用
US20220347315A1 (en) * 2019-11-22 2022-11-03 The University Of North Carolina At Chapel Hill Methods and compositions for increasing transduction efficiency with cell membrane fusion proteins
EP3827840A1 (en) * 2019-11-29 2021-06-02 Academisch Ziekenhuis Leiden h.o.d.n. LUMC Teipp peptide variant and uses thereof
CN116249555A (zh) 2020-05-19 2023-06-09 勃林格殷格翰国际有限公司 用于癌症治疗的结合分子
TW202227126A (zh) * 2020-09-14 2022-07-16 德商百靈佳殷格翰國際股份有限公司 異源初免加強疫苗
US20220111028A1 (en) * 2020-10-14 2022-04-14 Boehringer Ingelheim International Gmbh Combination Of A STING Agonist And A Complex Comprising A Cell Penetrating Peptide, A Cargo And A TLR Peptide Agonist
CN113480666B (zh) * 2021-08-13 2024-01-26 郑州伊美诺生物技术有限公司 Ca153融合蛋白及其制备方法和ca153检测质控品或校准品
CN113786481A (zh) * 2021-09-27 2021-12-14 深圳市中佳生物医疗科技有限公司 一种抗肿瘤疫苗及其制备方法
TW202346363A (zh) * 2022-03-16 2023-12-01 德商百靈佳殷格翰國際股份有限公司 腫瘤抗原、包含所述腫瘤抗原的化合物及其用途
KR102823824B1 (ko) 2022-08-10 2025-06-24 강원대학교산학협력단 Pde5 억제제 특이적 결합 도메인, 재조합 단백질 및 이의 용도
KR102886457B1 (ko) 2022-10-14 2025-11-18 강원대학교산학협력단 mTOR 억제제 특이적 결합 도메인, 재조합 단백질 및 이의 용도
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