IL260539B - שיטה לטיפול בגלומרולופתיה c3 - Google Patents
שיטה לטיפול בגלומרולופתיה c3Info
- Publication number
- IL260539B IL260539B IL260539A IL26053918A IL260539B IL 260539 B IL260539 B IL 260539B IL 260539 A IL260539 A IL 260539A IL 26053918 A IL26053918 A IL 26053918A IL 260539 B IL260539 B IL 260539B
- Authority
- IL
- Israel
- Prior art keywords
- glomerulopathy
- treating
- Prior art date
Links
- 208000029574 C3 glomerulopathy Diseases 0.000 title 1
- 208000027134 non-immunoglobulin-mediated membranoproliferative glomerulonephritis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662278788P | 2016-01-14 | 2016-01-14 | |
| US201662280346P | 2016-01-19 | 2016-01-19 | |
| US201662347450P | 2016-06-08 | 2016-06-08 | |
| US201662397527P | 2016-09-21 | 2016-09-21 | |
| PCT/US2017/013132 WO2017123716A1 (en) | 2016-01-14 | 2017-01-12 | Method of treating c3 glomerulopathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL260539B true IL260539B (he) | 2021-05-31 |
Family
ID=59312069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL260539A IL260539B (he) | 2016-01-14 | 2018-07-11 | שיטה לטיפול בגלומרולופתיה c3 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20170202821A1 (he) |
| EP (1) | EP3402486B1 (he) |
| JP (4) | JP7339733B2 (he) |
| KR (1) | KR102767008B1 (he) |
| CN (1) | CN108601790A (he) |
| AU (1) | AU2017207359C1 (he) |
| BR (2) | BR112018014222A2 (he) |
| CA (1) | CA3010735C (he) |
| ES (1) | ES3026359T3 (he) |
| IL (1) | IL260539B (he) |
| MA (1) | MA43872A (he) |
| MX (2) | MX2018008624A (he) |
| NZ (1) | NZ744083A (he) |
| RU (1) | RU2742888C2 (he) |
| SG (1) | SG11201805828YA (he) |
| TW (1) | TWI791423B (he) |
| WO (1) | WO2017123716A1 (he) |
| ZA (1) | ZA201804513B (he) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009330194B2 (en) | 2008-12-22 | 2015-07-09 | Chemocentryx, Inc. | C5aR antagonists |
| ES2632975T3 (es) | 2010-06-24 | 2017-09-18 | Chemocentryx, Inc. | Antagonistas de C5aR |
| EP3682879B1 (en) | 2014-09-29 | 2022-08-03 | ChemoCentryx, Inc. | Processes and intermediates in the preparation of c5ar antagonists |
| WO2017035409A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
| WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
| WO2017123716A1 (en) | 2016-01-14 | 2017-07-20 | Chemocentryx, Inc. | Method of treating c3 glomerulopathy |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| WO2018160891A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceutical, Inc. | Pharmaceutical compounds for treatment of medical disorders |
| EP3658657A1 (en) * | 2017-07-27 | 2020-06-03 | Procter & Gamble International Operations SA. | Phase-stable, sprayable freshening compositions comprising suspended particles |
| EP3661493A4 (en) | 2017-08-02 | 2021-04-14 | Achillion Pharmaceuticals, Inc. | TREATMENT DIET FOR THE TREATMENT OF PAROXYSTIC NOCTURAL HEMOGLOBINURIA |
| US20210215714A1 (en) * | 2018-05-25 | 2021-07-15 | Achillion Pharmaceuticals, Inc. | Complement alternative pathway-associated nephropathy biomarkers |
| EP3847174A4 (en) * | 2018-09-06 | 2022-06-15 | Achillion Pharmaceuticals, Inc. | MORPHIC FORMS OF COMPLEMENT D FACTOR INHIBITORS |
| EP3846803A4 (en) | 2018-09-06 | 2022-08-10 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| CA3114039A1 (en) | 2018-09-25 | 2020-04-02 | Achillion Pharmaceuticals, Inc. | Morphic forms of complement factor d inhibitors |
| BR112021010285A2 (pt) | 2018-11-30 | 2021-08-17 | Chemocentryx, Inc. | formulações de cápsula |
| KR20210104071A (ko) | 2018-12-17 | 2021-08-24 | 아칠리온 파르마세우티칼스 인코포레이티드 | 보체 매개 장애의 치료를 위한 표적 투약 |
| EP3938351A1 (en) | 2019-03-11 | 2022-01-19 | InflaRx GmbH | Fused piperidinyl bicyclic and related compounds as modulators of c5a receptor |
| MX2021011507A (es) | 2019-03-22 | 2021-12-15 | Achillion Pharmaceuticals Inc | Compuestos farmaceuticos para el tratamiento de trastornos mediados por complemento. |
| JP2023537062A (ja) * | 2020-08-07 | 2023-08-30 | キラ ファーマシューティカルズ （スージョウ） リミテッド | Ｃ５ａＲ阻害剤としての化合物 |
| KR20230124981A (ko) * | 2020-12-21 | 2023-08-28 | 케모센트릭스, 인크. | C5a 억제제를 사용한 c3 사구체병증의 치료 |
| CN115192563B (zh) * | 2022-05-09 | 2023-10-13 | 北京大学第一医院 | C3a/C3aR通路拮抗剂治疗原发性膜性肾病的用途 |
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| DK2994488T3 (da) | 2013-05-08 | 2022-10-03 | Novo Nordisk As | Anvendelse af c5ar-antagonister |
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| WO2017123716A1 (en) | 2016-01-14 | 2017-07-20 | Chemocentryx, Inc. | Method of treating c3 glomerulopathy |
| RU2748260C2 (ru) | 2016-04-04 | 2021-05-21 | Кемосентрикс, Инк. | РАСТВОРИМЫЕ С5аR АНТАГОНИСТЫ |
| KR20230124981A (ko) | 2020-12-21 | 2023-08-28 | 케모센트릭스, 인크. | C5a 억제제를 사용한 c3 사구체병증의 치료 |
-
2017
- 2017-01-12 WO PCT/US2017/013132 patent/WO2017123716A1/en not_active Ceased
- 2017-01-12 ES ES17738902T patent/ES3026359T3/es active Active
- 2017-01-12 NZ NZ744083A patent/NZ744083A/en unknown
- 2017-01-12 MX MX2018008624A patent/MX2018008624A/es unknown
- 2017-01-12 MA MA043872A patent/MA43872A/fr unknown
- 2017-01-12 US US15/404,610 patent/US20170202821A1/en not_active Abandoned
- 2017-01-12 JP JP2018536408A patent/JP7339733B2/ja active Active
- 2017-01-12 BR BR112018014222-0A patent/BR112018014222A2/pt not_active Application Discontinuation
- 2017-01-12 MX MX2022006069A patent/MX2022006069A/es unknown
- 2017-01-12 AU AU2017207359A patent/AU2017207359C1/en active Active
- 2017-01-12 BR BR122024002810-7A patent/BR122024002810A2/pt not_active Application Discontinuation
- 2017-01-12 KR KR1020187023360A patent/KR102767008B1/ko active Active
- 2017-01-12 CN CN201780006962.XA patent/CN108601790A/zh active Pending
- 2017-01-12 RU RU2018129378A patent/RU2742888C2/ru active
- 2017-01-12 SG SG11201805828YA patent/SG11201805828YA/en unknown
- 2017-01-12 CA CA3010735A patent/CA3010735C/en active Active
- 2017-01-12 EP EP17738902.0A patent/EP3402486B1/en active Active
- 2017-01-12 TW TW106100938A patent/TWI791423B/zh active
-
2018
- 2018-07-06 ZA ZA2018/04513A patent/ZA201804513B/en unknown
- 2018-07-11 IL IL260539A patent/IL260539B/he active IP Right Grant
- 2018-11-08 US US16/184,535 patent/US11285138B2/en active Active
-
2021
- 2021-08-06 JP JP2021129774A patent/JP2021183625A/ja active Pending
-
2022
- 2022-02-14 US US17/670,604 patent/US11779576B2/en active Active
-
2023
- 2023-06-20 JP JP2023100664A patent/JP2023126235A/ja active Pending
-
2024
- 2024-06-06 JP JP2024092498A patent/JP2024110998A/ja active Pending
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