IL259016A - Injectable botulinum toxin formulations and methods of using them with a long-term medical or cosmetic effect - Google Patents
Injectable botulinum toxin formulations and methods of using them with a long-term medical or cosmetic effectInfo
- Publication number
- IL259016A IL259016A IL259016A IL25901618A IL259016A IL 259016 A IL259016 A IL 259016A IL 259016 A IL259016 A IL 259016A IL 25901618 A IL25901618 A IL 25901618A IL 259016 A IL259016 A IL 259016A
- Authority
- IL
- Israel
- Prior art keywords
- therapeutic
- methods
- botulinum toxin
- long duration
- cosmetic effect
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0059—Cosmetic or alloplastic implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oral & Maxillofacial Surgery (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562248255P | 2015-10-29 | 2015-10-29 | |
PCT/US2016/059492 WO2017075468A1 (en) | 2015-10-29 | 2016-10-28 | Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect |
Publications (1)
Publication Number | Publication Date |
---|---|
IL259016A true IL259016A (en) | 2018-06-28 |
Family
ID=58630886
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL259016A IL259016A (en) | 2015-10-29 | 2018-04-29 | Injectable botulinum toxin formulations and methods of using them with a long-term medical or cosmetic effect |
IL286472A IL286472A (en) | 2015-10-29 | 2021-09-19 | Injectable botulinum toxin formulations and methods of using them with a long-term medical or cosmetic effect |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL286472A IL286472A (en) | 2015-10-29 | 2021-09-19 | Injectable botulinum toxin formulations and methods of using them with a long-term medical or cosmetic effect |
Country Status (16)
Country | Link |
---|---|
US (2) | US20180311333A1 (ru) |
EP (1) | EP3368071B1 (ru) |
JP (2) | JP6955491B2 (ru) |
KR (1) | KR20180077202A (ru) |
CN (1) | CN109069608A (ru) |
AU (2) | AU2016343748A1 (ru) |
BR (1) | BR112018008684A2 (ru) |
CA (1) | CA3003447A1 (ru) |
CO (1) | CO2018005361A2 (ru) |
DK (1) | DK3368071T3 (ru) |
ES (1) | ES2907652T3 (ru) |
IL (2) | IL259016A (ru) |
MX (1) | MX2018005256A (ru) |
RU (1) | RU2018119765A (ru) |
SG (2) | SG10202004337WA (ru) |
WO (1) | WO2017075468A1 (ru) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA200707352B (en) * | 2005-03-03 | 2009-04-29 | Revance Therapeutics Inc | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
BRPI1015938A2 (pt) | 2009-06-25 | 2016-09-27 | Revance Therapeutics Inc | formulações da toxina botulínica livre de albumina |
CN102666396B (zh) * | 2009-10-21 | 2015-05-13 | 雷文斯治疗公司 | 用于纯化非复合的肉毒杆菌神经毒素的方法和系统 |
EP3368071B1 (en) | 2015-10-29 | 2022-01-26 | ReVance Therapeutics, Inc. | Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect |
EP3541358A1 (en) | 2016-11-21 | 2019-09-25 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
CN110691579A (zh) * | 2017-03-22 | 2020-01-14 | 邦蒂公司 | 用于治疗的肉毒杆菌神经毒素 |
MX2019013716A (es) * | 2017-05-18 | 2020-10-12 | Revance Therapeutics Inc | Métodos de tratamiento para la distonía cervical. |
US11400136B2 (en) | 2017-06-19 | 2022-08-02 | President And Fellows Of Harvard College | Methods and compositions for treating a microbial infection |
WO2019090257A1 (en) * | 2017-11-03 | 2019-05-09 | Revance Therapeutics, Inc. | Botulinum toxin formulations and methods of use thereof in plantar fasciitis with extended duration of effect |
JP2021505570A (ja) * | 2017-12-04 | 2021-02-18 | ルバンス セラピュティックス インク.Revance Therapeutics,Inc. | 高い応答率及び長い効果の持続期間を有する注射可能なボツリヌス毒素製剤及びその使用方法 |
CA3112227A1 (en) * | 2018-09-13 | 2020-03-19 | Allergan, Inc. | Methods for treatment of masseter muscle hypertrophy |
SG11202110518XA (en) * | 2019-05-14 | 2021-10-28 | Eirion Therapeutics Inc | Delaying peak effect and/or extending duration of response |
CA3172150A1 (en) * | 2020-03-18 | 2021-09-23 | Revance Therapeutics, Inc. | Injectable botulinum toxin methods for treating headaches |
KR102397708B1 (ko) * | 2020-04-29 | 2022-05-16 | 한국화학연구원 | 탄닌산을 포함하는 보툴리눔 독소 약제학적 조성물 |
KR102324855B1 (ko) * | 2020-05-20 | 2021-11-11 | 오스템임플란트 주식회사 | 보툴리눔 독소를 포함하는 약제학적 액상 조성물 |
KR102266384B1 (ko) * | 2021-01-25 | 2021-06-21 | 주식회사 울트라브이 | 필러용 생분해성 고분자 미세입자, 이를 포함한 필러용 동결건조체, 그 제조방법 및 상기 동결건조체를 포함하는 필러용 주사제 |
WO2022228443A1 (en) * | 2021-04-26 | 2022-11-03 | Shanghaitech University | Intramuscular compositions of botulinum neurotoxins |
WO2023239229A1 (ko) * | 2022-06-10 | 2023-12-14 | (주)메디톡스 | 보툴리눔 독소 안정화 조성물, 이를 포함하는 보툴리눔 독소 제제 및 이에 사용하기 위한 폴리펩티드 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5877278A (en) | 1992-09-24 | 1999-03-02 | Chiron Corporation | Synthesis of N-substituted oligomers |
US6444209B1 (en) | 1996-10-28 | 2002-09-03 | Wisconsin Alumni Research Foundation | Hybrid botulinal neurotoxins |
CN1258379C (zh) | 2000-02-08 | 2006-06-07 | 阿勒根公司 | 肉毒杆菌毒素药物组合物 |
DE10043982A1 (de) * | 2000-09-05 | 2002-03-14 | Armin Maurer | Verfahren zur Verbesserung des Haarwuchses menschlichen Kopfhaares |
GB2416122A (en) | 2004-07-12 | 2006-01-18 | Ipsen Ltd | Botulinum neurotoxin composition |
KR102005930B1 (ko) | 2008-12-31 | 2019-07-31 | 레반스 테라퓨틱스, 아이엔씨. | 주사용 보툴리눔 독소 제제 |
BRPI1015938A2 (pt) * | 2009-06-25 | 2016-09-27 | Revance Therapeutics Inc | formulações da toxina botulínica livre de albumina |
JP6444032B2 (ja) * | 2011-01-07 | 2018-12-26 | ルバンス セラピュティックス インク.Revance Therapeutics,Inc. | 治療用又は美容用毒素組成物の局所塗布、除去及び不活化のための方法及びキット |
KR20140139010A (ko) * | 2012-03-22 | 2014-12-04 | 레반스 테라퓨틱스, 아이엔씨. | 국소 화학탈신경제를 이용한 주름 치료 방법 |
US20140120077A1 (en) * | 2012-10-28 | 2014-05-01 | Revance Therapeutics, Inc. | Compositions and Methods for Safe Treatment of Rhinitis |
EP3368071B1 (en) | 2015-10-29 | 2022-01-26 | ReVance Therapeutics, Inc. | Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect |
-
2016
- 2016-10-28 EP EP16860952.7A patent/EP3368071B1/en active Active
- 2016-10-28 WO PCT/US2016/059492 patent/WO2017075468A1/en active Application Filing
- 2016-10-28 ES ES16860952T patent/ES2907652T3/es active Active
- 2016-10-28 US US15/771,635 patent/US20180311333A1/en not_active Abandoned
- 2016-10-28 CA CA3003447A patent/CA3003447A1/en active Pending
- 2016-10-28 RU RU2018119765A patent/RU2018119765A/ru not_active Application Discontinuation
- 2016-10-28 MX MX2018005256A patent/MX2018005256A/es unknown
- 2016-10-28 SG SG10202004337WA patent/SG10202004337WA/en unknown
- 2016-10-28 JP JP2018522570A patent/JP6955491B2/ja active Active
- 2016-10-28 DK DK16860952.7T patent/DK3368071T3/da active
- 2016-10-28 KR KR1020187014681A patent/KR20180077202A/ko not_active Application Discontinuation
- 2016-10-28 CN CN201680072956.XA patent/CN109069608A/zh active Pending
- 2016-10-28 AU AU2016343748A patent/AU2016343748A1/en not_active Abandoned
- 2016-10-28 SG SG11201803566TA patent/SG11201803566TA/en unknown
- 2016-10-28 BR BR112018008684A patent/BR112018008684A2/pt active Search and Examination
-
2018
- 2018-04-29 IL IL259016A patent/IL259016A/en unknown
- 2018-05-23 CO CONC2018/0005361A patent/CO2018005361A2/es unknown
-
2021
- 2021-09-10 US US17/472,525 patent/US20220062400A1/en active Pending
- 2021-09-19 IL IL286472A patent/IL286472A/en unknown
- 2021-10-01 JP JP2021162802A patent/JP2022008814A/ja active Pending
-
2023
- 2023-10-06 AU AU2023241373A patent/AU2023241373A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20180077202A (ko) | 2018-07-06 |
IL286472A (en) | 2021-10-31 |
US20220062400A1 (en) | 2022-03-03 |
US20180311333A1 (en) | 2018-11-01 |
MX2018005256A (es) | 2019-09-04 |
BR112018008684A2 (pt) | 2018-11-27 |
WO2017075468A1 (en) | 2017-05-04 |
AU2023241373A1 (en) | 2023-10-26 |
ES2907652T3 (es) | 2022-04-25 |
CA3003447A1 (en) | 2017-05-04 |
CO2018005361A2 (es) | 2018-10-10 |
JP2022008814A (ja) | 2022-01-14 |
EP3368071A4 (en) | 2019-05-29 |
SG11201803566TA (en) | 2018-05-30 |
DK3368071T3 (da) | 2022-05-02 |
RU2018119765A (ru) | 2019-12-02 |
JP6955491B2 (ja) | 2021-10-27 |
EP3368071B1 (en) | 2022-01-26 |
EP3368071A1 (en) | 2018-09-05 |
CN109069608A (zh) | 2018-12-21 |
RU2018119765A3 (ru) | 2020-03-17 |
AU2016343748A1 (en) | 2018-05-17 |
JP2018531984A (ja) | 2018-11-01 |
SG10202004337WA (en) | 2020-06-29 |
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