SG10202004337WA - Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect - Google Patents

Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect

Info

Publication number
SG10202004337WA
SG10202004337WA SG10202004337WA SG10202004337WA SG10202004337WA SG 10202004337W A SG10202004337W A SG 10202004337WA SG 10202004337W A SG10202004337W A SG 10202004337WA SG 10202004337W A SG10202004337W A SG 10202004337WA SG 10202004337W A SG10202004337W A SG 10202004337WA
Authority
SG
Singapore
Prior art keywords
therapeutic
methods
botulinum toxin
long duration
cosmetic effect
Prior art date
Application number
SG10202004337WA
Inventor
Curtis L Ruegg
Jacob M Waugh
Original Assignee
Revance Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58630886&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10202004337W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Revance Therapeutics Inc filed Critical Revance Therapeutics Inc
Publication of SG10202004337WA publication Critical patent/SG10202004337WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0059—Cosmetic or alloplastic implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration
SG10202004337WA 2015-10-29 2016-10-28 Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect SG10202004337WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562248255P 2015-10-29 2015-10-29

Publications (1)

Publication Number Publication Date
SG10202004337WA true SG10202004337WA (en) 2020-06-29

Family

ID=58630886

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202004337WA SG10202004337WA (en) 2015-10-29 2016-10-28 Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect
SG11201803566TA SG11201803566TA (en) 2015-10-29 2016-10-28 Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201803566TA SG11201803566TA (en) 2015-10-29 2016-10-28 Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect

Country Status (16)

Country Link
US (2) US20180311333A1 (en)
EP (1) EP3368071B1 (en)
JP (2) JP6955491B2 (en)
KR (1) KR20180077202A (en)
CN (1) CN109069608A (en)
AU (2) AU2016343748A1 (en)
BR (1) BR112018008684A2 (en)
CA (1) CA3003447A1 (en)
CO (1) CO2018005361A2 (en)
DK (1) DK3368071T3 (en)
ES (1) ES2907652T3 (en)
IL (2) IL259016A (en)
MX (1) MX2018005256A (en)
RU (1) RU2018119765A (en)
SG (2) SG10202004337WA (en)
WO (1) WO2017075468A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102499981B (en) * 2005-03-03 2016-08-03 雷文斯治疗公司 For local application and the compositions of transdermal delivery of botulinum toxins and method
MX344583B (en) 2009-06-25 2016-12-20 Revance Therapeutics Inc Albumin-free botulinum toxin formulations.
CN102666396B (en) * 2009-10-21 2015-05-13 雷文斯治疗公司 Methods and systems for purifying non-complexed botulinum neurotoxin
KR20180077202A (en) 2015-10-29 2018-07-06 레반스 테라퓨틱스, 아이엔씨. Injectable botulinum toxin preparations and methods using these with long-lasting therapeutic or cosmetic effects
BR112019010131A2 (en) 2016-11-21 2019-10-08 Eirion Therapeutics Inc transdermal delivery of large agents
AU2018237198B2 (en) * 2017-03-22 2022-09-01 Bonti, Inc. Botulinum neurotoxins for use in therapy
EP3624819A4 (en) * 2017-05-18 2021-03-24 Revance Therapeutics, Inc. Methods of treatment for cervical dystonia
US20200390871A1 (en) * 2017-11-03 2020-12-17 Revance Therapeutics, Inc. Botulinum toxin formulations and methods of use thereof in plantar fascitis with extended duration of effect
US20200384090A1 (en) * 2017-12-04 2020-12-10 Revance Therapeutics, Inc. Injectable botulinum toxin formulations and methods of use thereof having high response rate and long effect duration
JP2022500417A (en) * 2018-09-13 2022-01-04 アラーガン、インコーポレイテッドAllergan, Incorporated How to treat masseter hypertrophy
CA3139983A1 (en) * 2019-05-14 2020-11-19 Eirion Therapeutics, Inc. Delaying peak effect and/or extending duration of response
WO2021188844A2 (en) * 2020-03-18 2021-09-23 Revance Therapeutics, Inc. Injectable botulinum toxin methods for treating headaches
KR102397708B1 (en) * 2020-04-29 2022-05-16 한국화학연구원 Botulinum toxin pharmaceutical composition comprising tannic acid
KR102324855B1 (en) * 2020-05-20 2021-11-11 오스템임플란트 주식회사 Pharmaceutical liquid composition comprising botulinum toxin
KR102266384B1 (en) * 2021-01-25 2021-06-21 주식회사 울트라브이 Biodegradable polymer fine particles for filler, freeze-dried product for filler including the same, preparing method thereof, injection for filler including the freeze-dried product
CN117561075A (en) * 2021-04-26 2024-02-13 上海科技大学 Intramuscular injection composition of botulinum neurotoxin
WO2023239229A1 (en) * 2022-06-10 2023-12-14 (주)메디톡스 Composition for stabilizing botulinum neurotoxin, botulinum neurotoxin formulation containing same, and polypeptides for use therein

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877278A (en) 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
US6444209B1 (en) 1996-10-28 2002-09-03 Wisconsin Alumni Research Foundation Hybrid botulinal neurotoxins
BR0108173A (en) 2000-02-08 2003-01-21 Allergan Inc Botulinum toxin pharmaceutical compositions
DE10043982A1 (en) * 2000-09-05 2002-03-14 Armin Maurer Process for improving the hair growth of human hair
HUE037595T2 (en) 2008-12-31 2018-09-28 Revance Therapeutics Inc Injectable botulinum toxin formulations
MX344583B (en) * 2009-06-25 2016-12-20 Revance Therapeutics Inc Albumin-free botulinum toxin formulations.
NO2661276T3 (en) * 2011-01-07 2017-12-30
JP2015514074A (en) * 2012-03-22 2015-05-18 ルバンス セラピュティックス インク．Ｒｅｖａｎｃｅ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． How to treat hemorrhoids using topical chemical nerve palsy drugs
WO2014066916A2 (en) * 2012-10-28 2014-05-01 Revance Therapeutics, Inc. Compositions and methods for safe treatment of rhinitis
KR20180077202A (en) 2015-10-29 2018-07-06 레반스 테라퓨틱스, 아이엔씨. Injectable botulinum toxin preparations and methods using these with long-lasting therapeutic or cosmetic effects

Also Published As

Publication number Publication date
DK3368071T3 (en) 2022-05-02
EP3368071A4 (en) 2019-05-29
JP2022008814A (en) 2022-01-14
CN109069608A (en) 2018-12-21
JP6955491B2 (en) 2021-10-27
IL259016A (en) 2018-06-28
CA3003447A1 (en) 2017-05-04
IL286472A (en) 2021-10-31
RU2018119765A3 (en) 2020-03-17
JP2018531984A (en) 2018-11-01
US20180311333A1 (en) 2018-11-01
MX2018005256A (en) 2019-09-04
AU2023241373A1 (en) 2023-10-26
SG11201803566TA (en) 2018-05-30
CO2018005361A2 (en) 2018-10-10
EP3368071A1 (en) 2018-09-05
KR20180077202A (en) 2018-07-06
EP3368071B1 (en) 2022-01-26
WO2017075468A1 (en) 2017-05-04
BR112018008684A2 (en) 2018-11-27
ES2907652T3 (en) 2022-04-25
AU2016343748A1 (en) 2018-05-17
US20220062400A1 (en) 2022-03-03
RU2018119765A (en) 2019-12-02

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