IL255354B - Stable nanomagnetic particle dispersions - Google Patents

Stable nanomagnetic particle dispersions

Info

Publication number
IL255354B
IL255354B IL255354A IL25535417A IL255354B IL 255354 B IL255354 B IL 255354B IL 255354 A IL255354 A IL 255354A IL 25535417 A IL25535417 A IL 25535417A IL 255354 B IL255354 B IL 255354B
Authority
IL
Israel
Prior art keywords
stable suspensions
nanomagnetic particles
nanomagnetic
particles
suspensions
Prior art date
Application number
IL255354A
Other languages
English (en)
Hebrew (he)
Other versions
IL255354A0 (en
Original Assignee
Biolegend Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolegend Inc filed Critical Biolegend Inc
Publication of IL255354A0 publication Critical patent/IL255354A0/en
Publication of IL255354B publication Critical patent/IL255354B/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Oncology (AREA)
IL255354A 2015-05-01 2017-10-31 Stable nanomagnetic particle dispersions IL255354B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562156141P 2015-05-01 2015-05-01
PCT/US2016/030327 WO2016179053A1 (en) 2015-05-01 2016-04-30 Stable nanomagnetic particle dispersions

Publications (2)

Publication Number Publication Date
IL255354A0 IL255354A0 (en) 2017-12-31
IL255354B true IL255354B (en) 2020-09-30

Family

ID=57205761

Family Applications (2)

Application Number Title Priority Date Filing Date
IL255354A IL255354B (en) 2015-05-01 2017-10-31 Stable nanomagnetic particle dispersions
IL277137A IL277137B (en) 2015-05-01 2020-09-03 Stable suspensions of nanomagnetic particles

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL277137A IL277137B (en) 2015-05-01 2020-09-03 Stable suspensions of nanomagnetic particles

Country Status (6)

Country Link
US (3) US10585088B2 (https=)
EP (1) EP3288912A4 (https=)
JP (1) JP6716683B2 (https=)
CN (1) CN107614458B (https=)
IL (2) IL255354B (https=)
WO (1) WO2016179053A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11291931B2 (en) 2014-12-15 2022-04-05 Akadeum Life Sciences, Inc. Method and system for buoyant separation
WO2016179053A1 (en) 2015-05-01 2016-11-10 BioLegend, Inc. Stable nanomagnetic particle dispersions
JP7007261B2 (ja) * 2015-08-20 2022-01-24 アルブミディクス リミティド アルブミン変異体及びコンジュゲート
EP3448981B1 (en) * 2016-04-30 2022-12-07 Biolegend, Inc. Compositions and methods for performing magnetibuoyant separations
CN110072993B (zh) 2016-12-16 2023-07-07 大集有限责任公司 由浮力实现的分离方法和系统
EP3820588A4 (en) 2018-07-09 2022-04-06 Akadeum Life Sciences, Inc. SYSTEM AND PROCESS FOR PROCESSING FLOATABLE PARTICLES
CN112823048A (zh) * 2018-07-27 2021-05-18 维拉维斯公司 消除和富集的方法
CN113646633A (zh) * 2018-10-17 2021-11-12 易兹代亚科技股份有限公司 生物材料侦测微颗粒和使用其的生物材料侦测方法
EP3693739A1 (de) * 2019-02-06 2020-08-12 Stefan Schreier Verfahren und vorrichtung zur isolierung von gewünschten zellen aus einer probe nicht-magnetischer biologischer materialien
FR3100338B1 (fr) * 2019-08-30 2022-09-02 Centre Nat Rech Scient Kit et méthode de capture d’une molécule
KR102272916B1 (ko) * 2019-09-27 2021-07-06 주식회사 이지다이아텍 새로운 암 poct 진단시스템
CN114845811B (zh) 2019-11-15 2024-08-02 新加坡国立大学 细胞外囊泡聚糖的磁性分析
CN112641955B (zh) * 2021-01-18 2022-04-19 四川大学 人间充质干细胞小囊泡作为靶向递药平台的应用
WO2023028329A1 (en) 2021-08-26 2023-03-02 Akadeum Life Sciences, Inc. Method and system for buoyant separation
CN113583865A (zh) * 2021-10-08 2021-11-02 深圳市瑞沃德生命科技有限公司 分选柱的制备方法及分选柱
CN114459877B (zh) * 2021-12-17 2024-05-10 中国计量科学研究院 用于富集外泌体的dna四面体复合磁性纳米材料及制备
US12196754B2 (en) 2022-04-01 2025-01-14 Akadeum Life Sciences, Inc. Method and system for buoyant-particle-assisted cell therapy
US12370266B2 (en) * 2022-09-13 2025-07-29 Core Quantum, Inc. Polymer composite nanomaterial encapsulation system
CN121511103A (zh) 2023-02-14 2026-02-10 爱卡德姆生命科学公司 用于部分或完全自动化的浮力辅助分离的方法和系统
EP4435045A1 (en) * 2023-03-21 2024-09-25 COSA Group GmbH Labelled particles

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933997A (en) 1974-03-01 1976-01-20 Corning Glass Works Solid phase radioimmunoassay of digoxin
GB1582956A (en) 1976-07-30 1981-01-21 Ici Ltd Composite magnetic particles
US4169804A (en) 1976-08-19 1979-10-02 Minnesota Mining And Manufacturing Company Magnetically responsive composite microparticle
US4267234A (en) 1978-03-17 1981-05-12 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US4230685A (en) 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
FR2480764B1 (fr) 1980-04-18 1985-10-04 Rhone Poulenc Spec Chim Latex de polymeres magnetiques et procede de preparation
IL63220A (en) 1981-07-01 1985-09-29 Yeda Res & Dev Process for production of polyacrolein microspheres
US4454234A (en) 1981-12-30 1984-06-12 Czerlinski George H Coated magnetizable microparticles, reversible suspensions thereof, and processes relating thereto
US4452773A (en) 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
NO155316C (no) 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
US4695392A (en) 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4554088A (en) 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US5246829A (en) 1984-10-04 1993-09-21 Immunotech Products for separation applicable to cells in the immunopurification field
FR2571498B1 (fr) 1984-10-04 1988-04-08 Immunotech Sa Procede de separation de cellules utilisant des anticorps et des billes de faible densite
US4582622A (en) 1984-10-12 1986-04-15 Fujirebio Kabushiki Kaisha Magnetic particulate for immobilization of biological protein and process of producing the same
US4795698A (en) 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US5512332A (en) 1985-10-04 1996-04-30 Immunivest Corporation Process of making resuspendable coated magnetic particles
US5597531A (en) 1985-10-04 1997-01-28 Immunivest Corporation Resuspendable coated magnetic particles and stable magnetic particle suspensions
US5069216A (en) * 1986-07-03 1991-12-03 Advanced Magnetics Inc. Silanized biodegradable super paramagnetic metal oxides as contrast agents for imaging the gastrointestinal tract
US5091206A (en) 1987-10-26 1992-02-25 Baxter Diagnostics Inc. Process for producing magnetically responsive polymer particles and application thereof
US4965007A (en) 1988-05-10 1990-10-23 Eastman Kodak Company Encapsulated superparamagnetic particles
US5108933A (en) 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations
US5385707A (en) 1988-12-28 1995-01-31 Stefan Miltenyi Metal matrices for use in high gradient magnetic separation of biological materials and method for coating the same
US5698271A (en) 1989-08-22 1997-12-16 Immunivest Corporation Methods for the manufacture of magnetically responsive particles
JP2979414B2 (ja) 1989-09-29 1999-11-15 富士レビオ株式会社 磁性粒子およびそれを用いた免疫測定法
US5169754A (en) 1990-10-31 1992-12-08 Coulter Corporation Biodegradable particle coatings having a protein covalently immobilized by means of a crosslinking agent and processes for making same
US5639620A (en) 1990-10-31 1997-06-17 Coulter Corporation Polymeric particles having a biodegradable gelatin or aminodextran coating and process for making same
US5186827A (en) 1991-03-25 1993-02-16 Immunicon Corporation Apparatus for magnetic separation featuring external magnetic means
US5610274A (en) 1991-11-20 1997-03-11 Cpg, Inc. Production and use of magnetic porous inorganic materials
AU670108B2 (en) * 1992-09-11 1996-07-04 Becton Dickinson & Company Improved antibodies to plasmodium falciparum
US5648124A (en) 1993-07-09 1997-07-15 Seradyn, Inc. Process for preparing magnetically responsive microparticles
US5411730A (en) 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
DE19528029B4 (de) 1995-07-31 2008-01-10 Chemagen Biopolymer-Technologie Aktiengesellschaft Magnetische Polymerpartikel auf der Basis von Polyvinylalkohol, Verfahren für ihre Herstellung und Verwendung
US20070036722A1 (en) 1996-10-28 2007-02-15 Pal Rongved Separation processes
AU7685498A (en) * 1997-05-14 1998-12-08 Weixin Tang Fully-coated, uniform-sized metallic particles
IL139034A0 (en) 1998-04-28 2001-11-25 Nycomed Imaging As Improvements in or relating to separation processes
JP2002535678A (ja) 1999-01-27 2002-10-22 バイエル コーポレイション 粒子のカゼインコーティングを用いる免疫アッセイ
US7169618B2 (en) 2000-06-28 2007-01-30 Skold Technology Magnetic particles and methods of producing coated magnetic particles
EP1311820B1 (en) * 2000-07-14 2015-02-11 Janssen Diagnostics, LLC Increased separation efficiency via controlled aggregation of magnetic nanoparticles
US20080194022A1 (en) 2000-08-03 2008-08-14 Clarke Michael F Isolation and use of solid tumor stem cells
ES2422193T3 (es) 2002-06-28 2013-09-09 Life Technologies Corp Métodos para restaurar el repertorio inmune en pacientes con defectos inmunológicos relacionados con la autoinmunidad y trasplante de órganos o de células madre hematopoyéticas
EP2302078B1 (en) 2004-11-03 2015-07-15 Iris Molecular Diagnostics, Inc. Microbubbles for affinity concentration
US20060216697A1 (en) * 2005-03-24 2006-09-28 General Electric Company Method of separating unattached Raman-active tag from bioassay or other reaction mixture
EP1715344A1 (en) * 2005-04-22 2006-10-25 Universiteit Utrecht Holding B.V. Immobilisation of antigenic carbohydrates to support detection of pathogenic micro-organisms
US7989065B2 (en) 2005-05-20 2011-08-02 Seradyn, Inc. Magnetically-responsive microparticles with improved response times
CN1312046C (zh) * 2005-07-07 2007-04-25 华中科技大学 一种超顺磁氧化铁复合纳米颗粒的制备方法
US20070026435A1 (en) 2005-07-28 2007-02-01 Polysciences, Inc. Hydroxysilane functionalized magnetic particles and nucleic acid separation method
CN101305087A (zh) * 2005-09-15 2008-11-12 阿尔特弥斯康复公司 用于磁富集细胞和其他颗粒的装置和方法
CN1951495B (zh) * 2005-10-25 2010-12-01 朱宏 恶性肿瘤磁热疗用纳米靶向药物
GB0616508D0 (en) 2006-08-18 2006-09-27 Iti Scotland Ltd Analyte manipulation and detection
JP2010502992A (ja) * 2006-09-05 2010-01-28 コロンバス ナノワークス，インコーポレーテッド 磁性粒子、並びにその作製及び使用方法
WO2011053435A1 (en) 2009-10-05 2011-05-05 Scientific Nanomedicine, Inc. Cell detection using targeted nanoparticles and magnetic properties thereof
GB0701641D0 (en) * 2007-01-29 2007-03-07 Iti Scotland Ltd Analyte manipulation and detection
CN101013132A (zh) * 2007-01-30 2007-08-08 上海师范大学 一种免疫荧光磁球及其制备方法和应用
US20110045081A1 (en) 2007-10-12 2011-02-24 Benedikt Steitz Magnetic, paramagnetic and/or superparamagnetic nanoparticles
CN101441210B (zh) * 2008-12-25 2013-08-28 上海交通大学 纳米磁性粒子层析试纸检测方法
JP5960146B2 (ja) * 2010-10-14 2016-08-02 ジャンセン ダイアグノスティックス，エルエルシー 多特異性捕捉試薬及び混合検出試薬を用いる膵臓患者の循環腫瘍細胞を検出する方法及びキット
CN102617810B (zh) 2012-02-27 2014-09-24 重庆医科大学 用两端带羧基的直链亲水聚合物包被纳米磁芯制备微纳米磁性材料的方法及其应用
JP5844195B2 (ja) * 2012-03-29 2016-01-13 三洋化成工業株式会社 磁性シリカ粒子並びにこれを用いた免疫測定法及び免疫測定用試薬
EP2831582A4 (en) 2012-03-31 2015-12-23 Nvigen Inc MULTIFUNCTIONAL NANOPARTICLES FOR SEPARATION, DETECTION AND QUANTIFICATION OF MOLECULES AND CELLS
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
JP2014156411A (ja) * 2013-02-14 2014-08-28 Toda Kogyo Corp 複合磁性微粒子粉末、分散体
CN103323603A (zh) * 2013-06-07 2013-09-25 博奥生物有限公司 一种在磁珠表面共价偶联蛋白质的方法
US20150219636A1 (en) 2014-01-28 2015-08-06 Targeson, Inc. Isolation of cells and biological substances using buoyant microbubbles
CN107206291A (zh) 2014-12-15 2017-09-26 爱卡德姆生命科学有限责任公司 用于浮力分离的方法和系统
WO2016179053A1 (en) 2015-05-01 2016-11-10 BioLegend, Inc. Stable nanomagnetic particle dispersions
EP3448981B1 (en) 2016-04-30 2022-12-07 Biolegend, Inc. Compositions and methods for performing magnetibuoyant separations

Also Published As

Publication number Publication date
JP6716683B2 (ja) 2020-07-01
CN107614458B (zh) 2021-05-11
EP3288912A1 (en) 2018-03-07
WO2016179053A1 (en) 2016-11-10
EP3288912A4 (en) 2018-11-07
US20160320376A1 (en) 2016-11-03
IL277137A (en) 2020-10-29
US11630104B2 (en) 2023-04-18
US12461095B2 (en) 2025-11-04
US20230160884A1 (en) 2023-05-25
US20200200746A1 (en) 2020-06-25
IL277137B (en) 2021-08-31
JP2018514794A (ja) 2018-06-07
US10585088B2 (en) 2020-03-10
CN107614458A (zh) 2018-01-19
IL255354A0 (en) 2017-12-31
CA2984506A1 (en) 2016-11-10

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