IL235085A - תוצרים גנטיים המבוטאים דיפרנציאלית בגידולים ושימושם - Google Patents
תוצרים גנטיים המבוטאים דיפרנציאלית בגידולים ושימושםInfo
- Publication number
- IL235085A IL235085A IL235085A IL23508514A IL235085A IL 235085 A IL235085 A IL 235085A IL 235085 A IL235085 A IL 235085A IL 23508514 A IL23508514 A IL 23508514A IL 235085 A IL235085 A IL 235085A
- Authority
- IL
- Israel
- Prior art keywords
- nucleic acid
- tumor
- expression
- seq
- cells
- Prior art date
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10211088A DE10211088A1 (de) | 2002-03-13 | 2002-03-13 | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| PCT/EP2003/002556 WO2003076631A2 (de) | 2002-03-13 | 2003-03-12 | Differentiell in tumoren exprimierte genprodukte und deren verwendung |
Publications (1)
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| IL235085A true IL235085A (he) | 2016-06-30 |
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| IL16390003A IL163900A0 (en) | 2002-03-13 | 2003-03-12 | Genetic products differentially expressed in tumors and use thereof |
| IL163900A IL163900A (he) | 2002-03-13 | 2004-09-02 | נוגדן הנקשר ל– tpte לשימוש באבחון, ניטור, מניעה או טיפול במחלת הסרטן ותכשירים רפואיים המכילים אותו |
| IL235085A IL235085A (he) | 2002-03-13 | 2014-10-07 | תוצרים גנטיים המבוטאים דיפרנציאלית בגידולים ושימושם |
| IL244596A IL244596A0 (he) | 2002-03-13 | 2016-03-14 | תוצרים גנטיים המבוטאים דיפרנציאלית בגידולים ושימושם |
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| IL16390003A IL163900A0 (en) | 2002-03-13 | 2003-03-12 | Genetic products differentially expressed in tumors and use thereof |
| IL163900A IL163900A (he) | 2002-03-13 | 2004-09-02 | נוגדן הנקשר ל– tpte לשימוש באבחון, ניטור, מניעה או טיפול במחלת הסרטן ותכשירים רפואיים המכילים אותו |
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| EP (18) | EP2277907A3 (he) |
| JP (5) | JP4963778B2 (he) |
| KR (4) | KR20120127536A (he) |
| CN (4) | CN1646692A (he) |
| AU (2) | AU2003219045B2 (he) |
| CA (3) | CA3035543A1 (he) |
| DE (1) | DE10211088A1 (he) |
| ES (3) | ES2688186T3 (he) |
| IL (4) | IL163900A0 (he) |
| MX (1) | MXPA04008867A (he) |
| NZ (1) | NZ535146A (he) |
| PL (1) | PL215160B1 (he) |
| WO (1) | WO2003076631A2 (he) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE10211088A1 (de) * | 2002-03-13 | 2003-09-25 | Ugur Sahin | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| US7361511B2 (en) * | 2002-08-20 | 2008-04-22 | Millenium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer |
| DE10341812A1 (de) * | 2003-09-10 | 2005-04-07 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| DE10344799A1 (de) | 2003-09-26 | 2005-04-14 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
| AU2015201738B2 (en) * | 2003-09-26 | 2016-10-13 | Biontech Ag | Identification of tumour-associated cell surface antigens for diagnosis and therapy |
| DE102004023187A1 (de) * | 2004-05-11 | 2005-12-01 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
| JP5089173B2 (ja) * | 2005-01-07 | 2012-12-05 | 独立行政法人理化学研究所 | 一塩基多型を用いた炎症性疾患の判定方法 |
| DE102005013846A1 (de) | 2005-03-24 | 2006-10-05 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
| US9492518B2 (en) * | 2006-10-04 | 2016-11-15 | Dana-Farber Cancer Institute, Inc. | Tumor immunity |
| EP2108701A1 (en) * | 2008-04-10 | 2009-10-14 | Ganymed Pharmaceuticals AG | Methods involving MS4A12 and agents targeting MS4A12 for therapy, diagnosis and testing |
| EP3572510B1 (en) | 2013-11-21 | 2022-09-21 | Repertoire Genesis Incorporation | T cell receptor and b cell receptor repertoire analysis system, and use of same in treatment and diagnosis |
| CN105992639B (zh) | 2014-03-21 | 2019-04-16 | 托普索公司 | 催化剂支座的免衬垫栅格模块及其模块化系统 |
| RU2711729C2 (ru) | 2014-12-09 | 2020-01-21 | Регенерон Фармасьютикалз, Инк. | Не относящиеся к человеку животные, имеющие гуманизированный ген кластера дифференцировки 274 |
| CN108601731A (zh) | 2015-12-16 | 2018-09-28 | 磨石肿瘤生物技术公司 | 新抗原的鉴别、制造及使用 |
| CA3078744A1 (en) | 2017-10-10 | 2019-04-18 | Gritstone Oncology, Inc. | Neoantigen identification using hotspots |
| CA3083097A1 (en) | 2017-11-22 | 2019-05-31 | Gritstone Oncology, Inc. | Reducing junction epitope presentation for neoantigens |
| CN110734925B (zh) * | 2018-07-20 | 2023-04-07 | 上海市免疫学研究所 | 一种粒细胞或单核细胞标记系统及其标记方法和应用 |
| WO2024002537A1 (en) | 2022-06-30 | 2024-01-04 | Kmc Kartoffelmelcentralen Amba | Starch based gelatine replacement products |
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| AU8192987A (en) * | 1986-12-01 | 1988-06-16 | Northwestern University | Human ldh-c4 cdna sequences encoding antigenic regions |
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| GB9019812D0 (en) | 1990-09-11 | 1990-10-24 | Scotgen Ltd | Novel antibodies for treatment and prevention of infection in animals and man |
| US5677139A (en) | 1995-04-21 | 1997-10-14 | President And Fellows Of Harvard College | In vitro differentiation of CD34+ progenitor cells into T lymphocytes |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US5990299A (en) * | 1995-08-14 | 1999-11-23 | Icn Pharmaceuticals, Inc. | Control of CD44 gene expression for therapeutic use |
| AU1705397A (en) * | 1996-01-16 | 1997-08-11 | Northwestern University | Proteins and peptides for contraceptive vaccines and fertility diagnosis |
| US5840839A (en) * | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
| JP2002503465A (ja) * | 1998-02-12 | 2002-02-05 | インサイト・ファーマスーティカルズ・インコーポレイテッド | ヒト受容体タンパク質 |
| JP3538381B2 (ja) * | 1998-05-21 | 2004-06-14 | ダイアデクスアス・インコーポレーテッド | 結腸癌を診断し、モニターし、そして病期決定する新規方法 |
| US6440663B1 (en) * | 1998-10-05 | 2002-08-27 | Ludwig Institute For Cancer Research | Renal cancer associated antigens and uses therefor |
| WO2001009345A1 (fr) * | 1999-07-29 | 2001-02-08 | Helix Research Institute | Nouveaux genes codant des proteines kinase et des proteines phosphatase |
| AU6181000A (en) * | 1999-07-29 | 2001-02-19 | Chugai Research Institute For Molecular Medicine, Inc. | Novel genes encoding protein kinase/protein phosphatase |
| DE19936563A1 (de) * | 1999-08-04 | 2001-02-08 | Boehringer Ingelheim Int | Tumorassoziiertes Antigen |
| EP1265582A2 (en) * | 1999-09-29 | 2002-12-18 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| US7442776B2 (en) | 1999-10-08 | 2008-10-28 | Young David S F | Cancerous disease modifying antibodies |
| AU2001229340A1 (en) * | 2000-01-14 | 2001-07-24 | Millennium Pharmaceuticals, Inc. | Genes compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
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| WO2001060860A2 (en) * | 2000-02-17 | 2001-08-23 | Millennium Predictive Medicine, Inc. | Genes differentially expressed in human prostate cancer and their use |
| AU6802801A (en) * | 2000-03-01 | 2001-09-24 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
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| AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| US20070015148A1 (en) * | 2001-01-25 | 2007-01-18 | Orr Michael S | Gene expression profiles in breast tissue |
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| US20040058341A1 (en) * | 2001-07-26 | 2004-03-25 | Y.Tom Tang | Protein phosphatases |
| NZ531674A (en) | 2001-09-18 | 2009-03-31 | Genentech Inc | Compositions and methods for the diagnosis and treatment of tumor |
| DE10211088A1 (de) * | 2002-03-13 | 2003-09-25 | Ugur Sahin | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| JP5565375B2 (ja) | 2011-05-12 | 2014-08-06 | 三菱電機株式会社 | 入退室管理装置 |
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2002
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2003
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- 2003-03-12 EP EP10010625A patent/EP2277903A3/de not_active Withdrawn
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- 2003-03-12 IL IL16390003A patent/IL163900A0/xx unknown
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- 2003-03-12 EP EP10010627A patent/EP2287181A3/de not_active Ceased
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2004
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2008
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2009
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2011
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2012
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- 2012-10-29 JP JP2012238202A patent/JP5756073B2/ja not_active Expired - Lifetime
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2013
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2014
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2015
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2016
- 2016-03-14 IL IL244596A patent/IL244596A0/he unknown
- 2016-09-22 US US15/273,378 patent/US20170101479A1/en not_active Abandoned
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