IL220839B - History of 3-phenylamino-9-azabicyclo[1.3.3]nonane and pharmaceutical preparations containing them - Google Patents
History of 3-phenylamino-9-azabicyclo[1.3.3]nonane and pharmaceutical preparations containing themInfo
- Publication number
- IL220839B IL220839B IL220839A IL22083912A IL220839B IL 220839 B IL220839 B IL 220839B IL 220839 A IL220839 A IL 220839A IL 22083912 A IL22083912 A IL 22083912A IL 220839 B IL220839 B IL 220839B
- Authority
- IL
- Israel
- Prior art keywords
- azabicyclo
- phenylamino
- pharmaceutical compositions
- nonane derivatives
- nonane
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29404410P | 2010-01-11 | 2010-01-11 | |
| PCT/US2011/020881 WO2011085389A1 (en) | 2010-01-11 | 2011-01-11 | Nicotinic acetylcholine receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL220839A0 IL220839A0 (en) | 2012-08-30 |
| IL220839B true IL220839B (en) | 2018-07-31 |
Family
ID=44258996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL220839A IL220839B (en) | 2010-01-11 | 2012-07-10 | History of 3-phenylamino-9-azabicyclo[1.3.3]nonane and pharmaceutical preparations containing them |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9062042B2 (enExample) |
| EP (1) | EP2523562B1 (enExample) |
| JP (1) | JP5840143B2 (enExample) |
| CN (1) | CN102905527B (enExample) |
| CA (1) | CA2787063C (enExample) |
| IL (1) | IL220839B (enExample) |
| MX (1) | MX2012008082A (enExample) |
| RU (1) | RU2560729C2 (enExample) |
| WO (1) | WO2011085389A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011085389A1 (en) | 2010-01-11 | 2011-07-14 | Astraea Therapeutics, Llc | Nicotinic acetylcholine receptor modulators |
| CN110804051B (zh) * | 2019-10-17 | 2020-10-20 | 杭州励德生物科技有限公司 | 一种格拉司琼中间体的制备方法 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198447A (en) | 1986-11-21 | 1993-03-30 | Glaxo Group Limited | Medicaments |
| US5200413A (en) | 1987-01-05 | 1993-04-06 | Beecham Group P.L.C. | Indolyl carboxamides useful treating migraine, cluster headache, trigeminal neuralgia or emesis |
| US4835162A (en) | 1987-02-12 | 1989-05-30 | Abood Leo G | Agonists and antagonists to nicotine as smoking deterents |
| EP0287196B1 (en) | 1987-02-18 | 1994-11-23 | Beecham Group Plc | Indole derivatives, process for their preparation and pharmaceutical compositions containing them |
| DE3822792C2 (de) | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
| US5223511A (en) | 1987-09-23 | 1993-06-29 | Boehringer Ingelheim Italia S.P.A. | Benzimidazoline-2-oxo-1-carboxylic acid compounds useful as 5-HT receptor antagonists |
| EP0315390B1 (en) | 1987-11-04 | 1994-07-20 | Beecham Group Plc | Novel 4-oxobenzotriazines and 4-oxoquinazolines |
| GB2236751B (en) | 1989-10-14 | 1993-04-28 | Wyeth John & Brother Ltd | Heterocyclic compounds |
| US5446050A (en) | 1989-11-17 | 1995-08-29 | Pfizer Inc. | Azabicyclo amides and esters as 5-HT3 receptor antagonists |
| JP3122671B2 (ja) | 1990-05-23 | 2001-01-09 | 協和醗酵工業株式会社 | 複素環式化合物 |
| JP3087763B2 (ja) * | 1990-11-30 | 2000-09-11 | 三井化学株式会社 | 新規な複素環式化合物およびそれを含有する医薬組成物 |
| US5491148A (en) | 1991-04-26 | 1996-02-13 | Syntex (U.S.A.) Inc. | Isoquinolinone and dihydroisoquinolinone 5-HT3 receptor antagonists |
| PH30413A (en) | 1992-03-26 | 1997-05-09 | Boehringer Ingelheim Italia | Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides |
| US5280028A (en) | 1992-06-24 | 1994-01-18 | G. D. Searle & Co. | Benzimidazole compounds |
| HUT74949A (en) | 1993-09-10 | 1997-03-28 | Cytomed | Epibatidine and derivatives thereof as cholinergic receptor agonists and antagonists |
| US5399562A (en) | 1994-02-04 | 1995-03-21 | G. D. Searle & Co. | Indolones useful as serotonergic agents |
| US6117889A (en) | 1994-04-01 | 2000-09-12 | University Of Virginia | 7-Azabicyclo-[2.2.1]-heptane and -heptene derivatives as analgesics and anti-inflammatory agents |
| GB9410441D0 (en) | 1994-05-25 | 1994-07-13 | Erba Carlo Spa | Azabicycloakyl derivatives of imidazo (1,5-a) indol-3-one and process for their preparation |
| CA2220768A1 (en) | 1996-03-13 | 1997-09-18 | Yale University | Smoking cessation treatments using naltrexone and related compounds |
| EE04057B1 (et) | 1997-05-30 | 2003-06-16 | Neurosearch A/S | 8-asabitsüklo[3,2,1]okt-2-eeni ja -oktaani derivaadid, nende valmistamismeetod, kasutamine ja farmatseutiline kompositsioon |
| WO1998054182A1 (en) | 1997-05-30 | 1998-12-03 | Neurosearch A/S | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS |
| JP4570773B2 (ja) | 1997-10-27 | 2010-10-27 | ニューロサーチ、アクティーゼルスカブ | ニコチン性アセチルコリンレセプターに於けるコリン作動性リガンドとしてのヘテロアリールジアザシクロアルカン |
| JP2002501891A (ja) | 1998-01-29 | 2002-01-22 | セプラコア インコーポレーテッド | 光学的に純粋な（＋）−ビュープロピオンの医薬用途 |
| IT1303123B1 (it) | 1998-10-13 | 2000-10-30 | Rotta Research Lab | Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed |
| NZ510287A (en) | 1998-11-27 | 2003-05-30 | Neurosearch As | 8-azabicyclo[3.2.1]oct-2-ene and -octane derivatives useful as cholinergic ligands at the nicotinic acetyl choline receptor |
| FR2788982B1 (fr) | 1999-02-02 | 2002-08-02 | Synthelabo | Compositions pharmaceutiques contenant de la nicotine et leur application dans le sevrage tabagique |
| DE10045112A1 (de) | 2000-09-11 | 2002-03-21 | Merck Patent Gmbh | Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems |
| IL158484A0 (en) | 2001-04-18 | 2004-05-12 | Euro Celtique Sa | Nociceptin analogs |
| US7199147B2 (en) * | 2001-06-12 | 2007-04-03 | Dainippon Sumitomo Pharma Co., Ltd. | Rho kinase inhibitors |
| AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
| AR036041A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen |
| US7642278B2 (en) | 2001-07-03 | 2010-01-05 | Novartis Vaccines And Diagnostics, Inc. | Indazole benzimidazole compounds |
| BR0212477A (pt) | 2001-09-12 | 2004-08-24 | Upjohn Co | 7-aza[2.2.1] bicicloheptanos substituìdos para o tratamento de doenças |
| US6951849B2 (en) | 2001-10-02 | 2005-10-04 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| MXPA04003007A (es) | 2001-10-02 | 2004-07-15 | Upjohn Co | Compuestos azabiciclico sustituidos condensados con heteroarilo para el tratamiento de enfermedades. |
| US6849620B2 (en) | 2001-10-26 | 2005-02-01 | Pfizer Inc | N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease |
| MXPA04004464A (es) | 2001-11-08 | 2004-08-11 | Upjohn Co | Compuestos de heteroarilo sustituido con azabiciclo para el tratamiento de enfermedades. |
| WO2003042210A1 (en) | 2001-11-09 | 2003-05-22 | Pharmacia & Upjohn Company | Azabicyclic-phenyl-fused-heterocyclic compounds and their use as alpha7 nachr ligands |
| US6852716B2 (en) | 2002-02-15 | 2005-02-08 | Pfizer Inc | Substituted-aryl compounds for treatment of disease |
| WO2003070731A2 (en) | 2002-02-19 | 2003-08-28 | Pharmacia & Upjohn Company | Azabicyclic compounds for the treatment of disease |
| WO2003070732A1 (en) | 2002-02-19 | 2003-08-28 | Pharmacia & Upjohn Company | Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease |
| US7176198B2 (en) | 2002-08-01 | 2007-02-13 | Pfizer Inc. | 1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease |
| JP2006506395A (ja) | 2002-11-01 | 2006-02-23 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | ＣＮＳ疾患の治療のための、α７ニコチンアゴニスト活性及び５ＨＴ３アンタゴニスト活性を有する化合物 |
| AU2003283648A1 (en) | 2002-12-06 | 2004-06-30 | Pharmacia & Upjohn Company Llc | Compounds as radioligands for the diagnosis of disease |
| PT1678172E (pt) | 2003-10-15 | 2010-03-03 | Targacept Inc | Composições farmacêuticas e métodos para alívio da dor e tratamento de perturbações do sistema nervoso central |
| WO2005060947A2 (en) | 2003-12-19 | 2005-07-07 | Sri International | Agonist and antagonist ligands of the nociceptin receptor |
| BRPI0417323A (pt) | 2003-12-22 | 2007-03-27 | Memory Pharm Corp | indóis, 1h-indazóis, 1,2-benzisoxazóis, e 1,2-benzisotiazóis, composto, composição farmacêutica e usos dos mesmos |
| JP2007534692A (ja) | 2004-04-22 | 2007-11-29 | メモリー・ファーマシューティカルズ・コーポレイション | インドール、１ｈ−インダゾール、１，２−ベンズイソキサゾール、１，２−ベンゾイソチアゾール、ならびにその調製および使用 |
| DE602005027452D1 (de) | 2004-05-07 | 2011-05-26 | Memory Pharm Corp | 1h-indazole, benzothiazole, 1,2-benzisoxazole, 1,2-benzisothiazole und chromone und deren herstellung und verwendungen |
| EP1831215A1 (en) | 2004-11-23 | 2007-09-12 | Ranbaxy Laboratories Limited | Pyrido[2,3-d]pyrimidines as anti-inflamatory agents |
| TW200745101A (en) | 2005-09-30 | 2007-12-16 | Organon Nv | 9-Azabicyclo[3.3.1]nonane derivatives |
| US7868017B2 (en) * | 2005-09-30 | 2011-01-11 | N.V. Organon | 9-azabicyclo[3.3.1]nonane derivatives |
| BRPI0616667B1 (pt) * | 2005-10-06 | 2017-07-18 | Nippon Soda Co. , Ltd. | Compounds of cyclical amine or salts thereof or non-oxides thereof, and agents for control of fever |
| BRPI0716069A2 (pt) | 2006-08-07 | 2013-09-17 | Albany Molecular Res Inc | composto, composiÇço farmacÊutica, e, mÉtodo para tratar um distérbio |
| GB0719644D0 (en) * | 2007-10-05 | 2007-11-14 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| US8697722B2 (en) | 2007-11-02 | 2014-04-15 | Sri International | Nicotinic acetylcholine receptor modulators |
| WO2009058120A1 (en) * | 2007-11-02 | 2009-05-07 | Sri International | Nicotinic acetylcholine receptor modulators |
| WO2009067579A1 (en) | 2007-11-21 | 2009-05-28 | Abbott Laboratories | Biaryl substituted azabicyclic alkane derivatives as nicotinic acetylcholine receptor activity modulators |
| PL2356113T3 (pl) | 2008-11-14 | 2015-06-30 | Bayer Ip Gmbh | Heterocyklicznie podstawione związki arylowe jako inhibitory HIF |
| EP2415765A4 (en) | 2009-03-30 | 2012-08-15 | Astellas Pharma Inc | PYRIMIDINE COMPOUND |
| WO2011085389A1 (en) | 2010-01-11 | 2011-07-14 | Astraea Therapeutics, Llc | Nicotinic acetylcholine receptor modulators |
-
2011
- 2011-01-11 WO PCT/US2011/020881 patent/WO2011085389A1/en not_active Ceased
- 2011-01-11 CA CA2787063A patent/CA2787063C/en active Active
- 2011-01-11 RU RU2012129257/04A patent/RU2560729C2/ru active
- 2011-01-11 EP EP11732326.1A patent/EP2523562B1/en active Active
- 2011-01-11 CN CN201180013438.8A patent/CN102905527B/zh active Active
- 2011-01-11 US US13/004,801 patent/US9062042B2/en active Active
- 2011-01-11 MX MX2012008082A patent/MX2012008082A/es active IP Right Grant
- 2011-01-11 JP JP2012548234A patent/JP5840143B2/ja active Active
-
2012
- 2012-07-10 IL IL220839A patent/IL220839B/en active IP Right Grant
-
2015
- 2015-01-20 US US14/601,194 patent/US9670198B2/en active Active
-
2017
- 2017-04-23 US US15/494,505 patent/US10085975B2/en active Active
-
2018
- 2018-07-17 US US16/037,001 patent/US20180318270A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20170224665A1 (en) | 2017-08-10 |
| IL220839A0 (en) | 2012-08-30 |
| US9062042B2 (en) | 2015-06-23 |
| US10085975B2 (en) | 2018-10-02 |
| EP2523562B1 (en) | 2019-01-02 |
| US20150148541A1 (en) | 2015-05-28 |
| RU2012129257A (ru) | 2014-02-20 |
| EP2523562A1 (en) | 2012-11-21 |
| US9670198B2 (en) | 2017-06-06 |
| CN102905527A (zh) | 2013-01-30 |
| EP2523562A4 (en) | 2013-04-17 |
| RU2560729C2 (ru) | 2015-08-20 |
| CA2787063C (en) | 2018-11-27 |
| JP2013516496A (ja) | 2013-05-13 |
| MX2012008082A (es) | 2013-02-07 |
| US20180318270A1 (en) | 2018-11-08 |
| US20110172264A1 (en) | 2011-07-14 |
| JP5840143B2 (ja) | 2016-01-06 |
| CN102905527B (zh) | 2016-08-24 |
| CA2787063A1 (en) | 2011-07-14 |
| WO2011085389A1 (en) | 2011-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL279304A (en) | History of cytotoxic benzodiazepines, preparations containing them and their uses | |
| IL221952A (en) | Annotations 2, 3-Dihydro-1h - Indene-1-Il-7,2- Diazaspiro [5.3] Noonan and Pharmaceuticals Containing Them | |
| IL256921A (en) | Pyrazolopyrimidines, pharmaceutical preparations containing them and their use | |
| IL224288A (en) | Derivatives of converted pyrazolamide, pharmaceutical preparations containing them and their use | |
| IL217912A (en) | History of 5-Amino-1-Benzimidazole-Pyrazole and Pharmaceutical Preparations Containing It | |
| IL213993A (en) | History of 4,3,2,1-tetrahydropyrido [3,2-b] pyrazine-2-one and pharmaceutical preparations containing them | |
| IL214175A (en) | Derivatives of aminotetralin, their pharmaceutical compositions and their use | |
| IL216254A (en) | Compounds, pharmaceutical compositions and their uses | |
| ZA201300920B (en) | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | |
| IL228322A0 (en) | History of dispiropyrrolidine, preparations containing them and their uses | |
| IL224976A (en) | Converted history of 1h - indazole and a pharmaceutical preparation containing them | |
| PL2562172T3 (pl) | Pochodne sfelaktonu, ich kompozycje farmaceutyczne, sposoby wytwarzania i zastosowania | |
| IL216768A0 (en) | Aminopyrrolidinone derivatives compositions comprising the same and uses thereof | |
| IL221209A0 (en) | Pyrazolo piperidine derivatives, compositions comprising the same and uses thereof | |
| IL221207A0 (en) | Pyrazolo piperidine derivatives, compositions comprising the same and uses thereof | |
| IL225824A0 (en) | History of quinoxaline, their preparation and pharmaceutical preparations containing them | |
| IL225626A0 (en) | The history of pyrrolidinone, their preparation and remote preparations containing them | |
| IL223463A (en) | Urea History, Pharmaceutical Preparations Containing and Uses | |
| IL218490A (en) | Oxazolopyrimidinones dihydro hydroxybencyalkyloxymethyl are converted, preparations containing them and their use in the preparation of pharmaceutical preparations | |
| IL206808A (en) | Indolyl-pyridone history, their pharmaceutical preparations and their uses | |
| ZA201209739B (en) | Levocarrimycin,pharmaceutical compositions,preparation methods and uses thereof | |
| IL226094A0 (en) | The history of pyrazine, their preparation and pharmaceutical preparations containing them | |
| IL236057B (en) | History of 4,2,1-triazine-6-carboxamide and pharmaceutical preparations containing them | |
| IL206594A (en) | The history of azinone-tetrahydropyridoindole and its containing pharmaceutical preparations | |
| IL215497A0 (en) | Oxadiazile derivatives and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |