IL219965A0 - Novel antiviral compounds - Google Patents
Novel antiviral compoundsInfo
- Publication number
- IL219965A0 IL219965A0 IL219965A IL21996512A IL219965A0 IL 219965 A0 IL219965 A0 IL 219965A0 IL 219965 A IL219965 A IL 219965A IL 21996512 A IL21996512 A IL 21996512A IL 219965 A0 IL219965 A0 IL 219965A0
- Authority
- IL
- Israel
- Prior art keywords
- antiviral compounds
- novel antiviral
- novel
- compounds
- antiviral
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0922520A GB0922520D0 (en) | 2009-12-23 | 2009-12-23 | Novel antiviral compounds |
| GBGB1001204.5A GB201001204D0 (en) | 2010-01-26 | 2010-01-26 | Novel antiviral compounds |
| PCT/EP2010/070306 WO2011076765A1 (en) | 2009-12-23 | 2010-12-20 | Novel antiviral compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL219965A0 true IL219965A0 (en) | 2012-07-31 |
Family
ID=44246874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL219965A IL219965A0 (en) | 2009-12-23 | 2012-05-23 | Novel antiviral compounds |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20120316161A1 (https=) |
| EP (1) | EP2516008B1 (https=) |
| JP (1) | JP2013515692A (https=) |
| KR (1) | KR101483834B1 (https=) |
| CN (1) | CN102770181B (https=) |
| AU (1) | AU2010334958B2 (https=) |
| CA (1) | CA2781780C (https=) |
| ES (1) | ES2475970T3 (https=) |
| IL (1) | IL219965A0 (https=) |
| MX (1) | MX2012007410A (https=) |
| PT (1) | PT2516008E (https=) |
| SG (2) | SG10201408512RA (https=) |
| WO (1) | WO2011076765A1 (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0908394D0 (en) | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
| GB0913636D0 (en) | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
| KR20130124291A (ko) | 2010-07-02 | 2013-11-13 | 길리애드 사이언시즈, 인코포레이티드 | Ｈｉｖ 항바이러스 화합물로서의 2-퀴놀리닐-아세트산 유도체 |
| AP2013006706A0 (en) | 2010-07-02 | 2013-02-28 | Gilead Sciences Inc | Napht-2-ylacetic acid derivatives to treat AIDS |
| US8633200B2 (en) | 2010-09-08 | 2014-01-21 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| WO2012066442A1 (en) | 2010-11-15 | 2012-05-24 | Pfizer Limited | Inhibitors of hiv replication |
| JP2013542243A (ja) | 2010-11-15 | 2013-11-21 | カトリーケ ウニヴェルシテイト ルーヴェン | 新規な抗ウイルス性化合物 |
| ES2742261T3 (es) | 2011-04-15 | 2020-02-13 | Hivih | Inhibidores de la replicación viral, su proceso de preparación y sus usos terapéuticos |
| BR112013027096A2 (pt) | 2011-04-21 | 2016-12-27 | Gilead Sciences Inc | compostos de benzotiazol e seu uso farmacêutico |
| US8791108B2 (en) | 2011-08-18 | 2014-07-29 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| EP2772480B2 (en) | 2011-10-25 | 2020-12-09 | Shionogi & Co., Ltd. | Hiv replication inhibitor |
| CA2858096C (en) * | 2011-12-22 | 2020-06-23 | Gilead Sciences, Inc. | Pyrazolo[1,5-a]pyrimidines as antiviral agents |
| US9284323B2 (en) | 2012-01-04 | 2016-03-15 | Gilead Sciences, Inc. | Naphthalene acetic acid derivatives against HIV infection |
| WO2013103724A1 (en) | 2012-01-04 | 2013-07-11 | Gilead Sciences, Inc. | 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids |
| US8629276B2 (en) | 2012-02-15 | 2014-01-14 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| US9034882B2 (en) * | 2012-03-05 | 2015-05-19 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| US9006235B2 (en) | 2012-03-06 | 2015-04-14 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| ES2571479T3 (es) | 2012-04-20 | 2016-05-25 | Gilead Sciences Inc | Derivados del ácido benzotiazol-6-il acético y su uso para tratar una infección por VIH |
| US8906929B2 (en) | 2012-08-16 | 2014-12-09 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| EP2719685A1 (en) | 2012-10-11 | 2014-04-16 | Laboratoire Biodim | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
| TW201441197A (zh) | 2013-01-31 | 2014-11-01 | Shionogi & Co | Ｈｉｖ複製抑制劑 |
| CN105008358B (zh) | 2013-03-13 | 2017-12-29 | 百时美施贵宝公司 | 人免疫缺陷病毒复制的抑制剂 |
| WO2014164467A1 (en) | 2013-03-13 | 2014-10-09 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| JP2016516692A (ja) | 2013-03-13 | 2016-06-09 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ヒト免疫不全ウイルス複製の阻害剤 |
| JP6268656B2 (ja) | 2013-03-14 | 2018-01-31 | ビーブ・ヘルスケア・ユーケイ・（ナンバー５）・リミテッドＶｉｉＶ Ｈｅａｌｔｈｃａｒｅ ＵＫ （Ｎｏ．５） Ｌｉｍｉｔｅｄ | ヒト免疫不全ウイルス複製の阻害剤 |
| US9527842B2 (en) | 2013-03-14 | 2016-12-27 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| EP2821082A1 (en) | 2013-07-05 | 2015-01-07 | Laboratoire Biodim | Method of producing an inactivated lentivirus, especially HIV, vaccine, kit and method of use |
| JP6616190B2 (ja) * | 2014-02-07 | 2019-12-04 | 国立大学法人 東京医科歯科大学 | 筋形成促進剤、筋萎縮抑制剤、医薬組成物及びｔａｚ活性化剤 |
| WO2015123230A1 (en) | 2014-02-12 | 2015-08-20 | Bristol-Myers Squibb Company | Benzothiazole macrocycles as inhibitors of human immunodeficiency virus replication |
| EP3152211A1 (en) | 2014-02-12 | 2017-04-12 | ViiV Healthcare UK (No.5) Limited | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9932353B2 (en) | 2014-02-18 | 2018-04-03 | Viiv Healthcare Uk (No. 5) Limited | Imidazopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9409922B2 (en) | 2014-02-18 | 2016-08-09 | Bristol-Myers Squibb Company | Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9834566B2 (en) | 2014-02-18 | 2017-12-05 | VIIV Healthcare UK (No.5) Limited | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9273067B2 (en) | 2014-02-19 | 2016-03-01 | Bristol-Myers Squibb Company | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| ES2687322T3 (es) | 2014-02-19 | 2018-10-24 | VIIV Healthcare UK (No.5) Limited | Inhibidores de la replicación del virus de inmunodeficiencia humana |
| PT3116880T (pt) | 2014-02-20 | 2018-05-10 | Viiv Healthcare Uk No 5 Ltd | Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humana |
| US9193720B2 (en) | 2014-02-20 | 2015-11-24 | Bristol-Myers Squibb Company | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| EP3144311A4 (en) | 2014-05-16 | 2018-01-03 | Shionogi & Co., Ltd. | Tricyclic heterocyclic derivative having hiv replication-inhibiting effect |
| KR101692478B1 (ko) | 2014-07-10 | 2017-01-05 | 계명대학교 산학협력단 | Ｓｙ０２９를 유효성분으로 함유하는 항바이러스 조성물 |
| MX2017015256A (es) | 2015-05-29 | 2018-02-19 | Shionogi & Co | Derivados triciclicos que contienen nitrogeno que tienen actividad inhibidora de la replicacion del virus de inmunodeficiencia adquirida (vih). |
| WO2017006261A1 (en) | 2015-07-06 | 2017-01-12 | VIIV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| US10221156B2 (en) | 2015-07-08 | 2019-03-05 | VIIV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| AU2016290205A1 (en) | 2015-07-09 | 2018-01-18 | VIIV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| CN107820492A (zh) | 2015-07-09 | 2018-03-20 | Viiv保健英国第五有限公司 | 作为人类免疫缺陷病毒复制抑制剂的吡啶‑3‑基乙酸衍生物 |
| BR112018002403A2 (pt) | 2015-08-07 | 2018-09-18 | Viiv Healthcare Uk No 5 Ltd | composto, e, composição útil e método para tratar infecção de hiv |
| AU2016305338A1 (en) | 2015-08-10 | 2018-03-01 | VIIV Healthcare UK (No.5) Limited | Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication |
| AR105653A1 (es) | 2015-08-11 | 2017-10-25 | VIIV HEALTHCARE UK (Nº 5) LTD | Derivados del ácido 5-(n-bencil-tetrahidroisoquinolin-6-il)-piridin-3-il acético como inhibidores de la replicación del virus de la inmunodeficiencia humana |
| PT3334723T (pt) | 2015-08-12 | 2019-12-19 | Viiv Healthcare Uk No 5 Ltd | Composto, composição, e, método para tratar infecção por hiv |
| TW201718537A (zh) | 2015-08-12 | 2017-06-01 | Ｖｉｉｖ醫療保健英國（Ｎｏ．５）有限公司 | 做為人類免疫缺陷病毒複製抑制劑之吡啶－３－基乙酸衍生物 |
| EP3334722A1 (en) | 2015-08-12 | 2018-06-20 | VIIV Healthcare UK (No.5) Limited | 5-(n-fused tricyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3- yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| AU2016307987B2 (en) | 2015-08-20 | 2018-08-30 | VIIV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| JP2019515000A (ja) | 2016-05-11 | 2019-06-06 | ヴィーブ ヘルスケア ユーケー（ナンバー５）リミテッド | ヒト免疫不全ウイルス複製の阻害剤としてのピリジン−３−イル酢酸誘導体 |
| JP2019515939A (ja) | 2016-05-11 | 2019-06-13 | ヴィーブ ヘルスケア ユーケー（ナンバー５）リミテッド | ヒト免疫不全ウイルス複製の阻害剤としてのピリジン−３−イル酢酸誘導体 |
| US10407410B2 (en) | 2016-05-11 | 2019-09-10 | VIIV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| JP2020503352A (ja) | 2017-01-03 | 2020-01-30 | ヴィーブ ヘルスケア ユーケー（ナンバー５）リミテッド | ヒト免疫不全ウイルス複製の阻害剤としてのピリジン−３−イル酢酸誘導体 |
| EP3565809A1 (en) | 2017-01-03 | 2019-11-13 | ViiV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| WO2019244066A2 (en) | 2018-06-19 | 2019-12-26 | VIIV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| WO2020003093A1 (en) | 2018-06-25 | 2020-01-02 | VIIV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100191774B1 (ko) * | 1991-04-22 | 1999-06-15 | 오스카 아끼히꼬 | 피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제 |
| US5543523A (en) | 1994-11-15 | 1996-08-06 | Regents Of The University Of Minnesota | Method and intermediates for the synthesis of korupensamines |
| JP3616628B2 (ja) * | 2001-03-01 | 2005-02-02 | 塩野義製薬株式会社 | Ｈｉｖインテグラーゼ阻害活性を有する含窒素芳香族複素環化合物 |
| JP2003171381A (ja) | 2001-09-25 | 2003-06-20 | Takeda Chem Ind Ltd | エントリー阻害剤 |
| JP2003119137A (ja) | 2001-10-10 | 2003-04-23 | Japan Tobacco Inc | Ｈｉｖ阻害剤 |
| EP1441734B1 (en) | 2001-10-26 | 2007-02-28 | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. | Dihydroxypyrimidine carboxamide inhibitors of hiv integrase |
| JP4497347B2 (ja) | 2001-12-05 | 2010-07-07 | 塩野義製薬株式会社 | Ｈｉｖインテグラーゼ阻害活性を有する誘導体 |
| JP2005515206A (ja) | 2001-12-12 | 2005-05-26 | ブリストル−マイヤーズ スクイブ カンパニー | Ｈｉｖインテグラーゼ・インヒビター |
| JP4578101B2 (ja) | 2001-12-21 | 2010-11-10 | テイボテク・フアーマシユーチカルズ・リミテツド | 幅広いスペクトルのｈｉｖプロテアーゼ阻害剤である複素環置換フェニル含有スルホンアミド |
| EP1467970B1 (en) | 2002-01-17 | 2007-08-22 | Merck & Co., Inc. | Hydroxynaphthyridinone carboxamides useful as hiv integrase inhibitors |
| TW200306192A (en) | 2002-01-18 | 2003-11-16 | Bristol Myers Squibb Co | Tricyclic 2-pyrimidone compounds useful as HIV reverse transcriptase inhibitors |
| US7449488B2 (en) | 2002-06-04 | 2008-11-11 | Schering Corporation | Pyrazolopyrimidines as protein kinase inhibitors |
| PA8586801A1 (es) * | 2002-10-31 | 2005-02-04 | Pfizer | Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso |
| JP5269087B2 (ja) * | 2007-11-16 | 2013-08-21 | ギリアード サイエンシス インコーポレーテッド | ヒト免疫不全ウイルス複製のインヒビター |
-
2010
- 2010-12-20 SG SG10201408512RA patent/SG10201408512RA/en unknown
- 2010-12-20 WO PCT/EP2010/070306 patent/WO2011076765A1/en not_active Ceased
- 2010-12-20 KR KR1020127019420A patent/KR101483834B1/ko not_active Expired - Fee Related
- 2010-12-20 MX MX2012007410A patent/MX2012007410A/es active IP Right Grant
- 2010-12-20 EP EP10801407.7A patent/EP2516008B1/en not_active Not-in-force
- 2010-12-20 SG SG2012035002A patent/SG181423A1/en unknown
- 2010-12-20 CN CN201080064636.2A patent/CN102770181B/zh not_active Expired - Fee Related
- 2010-12-20 AU AU2010334958A patent/AU2010334958B2/en not_active Ceased
- 2010-12-20 CA CA2781780A patent/CA2781780C/en not_active Expired - Fee Related
- 2010-12-20 PT PT108014077T patent/PT2516008E/pt unknown
- 2010-12-20 ES ES10801407.7T patent/ES2475970T3/es active Active
- 2010-12-20 US US13/518,434 patent/US20120316161A1/en not_active Abandoned
- 2010-12-20 JP JP2012545282A patent/JP2013515692A/ja not_active Ceased
-
2012
- 2012-05-23 IL IL219965A patent/IL219965A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN102770181A (zh) | 2012-11-07 |
| ES2475970T3 (es) | 2014-07-11 |
| SG181423A1 (en) | 2012-07-30 |
| WO2011076765A1 (en) | 2011-06-30 |
| JP2013515692A (ja) | 2013-05-09 |
| KR101483834B1 (ko) | 2015-01-16 |
| AU2010334958A1 (en) | 2012-06-07 |
| MX2012007410A (es) | 2012-07-17 |
| KR20120106869A (ko) | 2012-09-26 |
| AU2010334958B2 (en) | 2015-02-05 |
| US20120316161A1 (en) | 2012-12-13 |
| PT2516008E (pt) | 2014-07-16 |
| CA2781780A1 (en) | 2011-06-30 |
| CN102770181B (zh) | 2015-08-12 |
| SG10201408512RA (en) | 2015-02-27 |
| CA2781780C (en) | 2015-02-17 |
| EP2516008A1 (en) | 2012-10-31 |
| EP2516008B1 (en) | 2014-04-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20171759T8 (hr) | Antiviralni spojevi | |
| IL219965A0 (en) | Novel antiviral compounds | |
| IL226004A0 (en) | New antiviral compounds | |
| IL216026A0 (en) | Heterocyckic antiviral compounds | |
| EP2512242A4 (en) | NEW COMPOUNDS | |
| GB0919433D0 (en) | Novel compounds | |
| ZA201203613B (en) | Novel antiviral compounds | |
| GB0922520D0 (en) | Novel antiviral compounds | |
| GB0908677D0 (en) | Antiviral compounds | |
| GB0914473D0 (en) | Antiviral compounds | |
| GB0906209D0 (en) | Antiviral compounds | |
| GB201001204D0 (en) | Novel antiviral compounds | |
| GB0816600D0 (en) | Antiviral compounds | |
| IL192335A0 (en) | Antiviral compounds | |
| GB0819528D0 (en) | Antiviral compounds | |
| GB0907112D0 (en) | Novel compounds | |
| GB0907117D0 (en) | Novel compounds | |
| GB0910680D0 (en) | Novel compounds |