IL216954A - Protein folding by using oxidation-chemically controlled courtship mode - Google Patents

Protein folding by using oxidation-chemically controlled courtship mode

Info

Publication number
IL216954A
IL216954A IL216954A IL21695411A IL216954A IL 216954 A IL216954 A IL 216954A IL 216954 A IL216954 A IL 216954A IL 21695411 A IL21695411 A IL 21695411A IL 216954 A IL216954 A IL 216954A
Authority
IL
Israel
Prior art keywords
redox state
refolding proteins
chemically controlled
controlled redox
chemically
Prior art date
Application number
IL216954A
Other languages
English (en)
Hebrew (he)
Other versions
IL216954A0 (en
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42710673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL216954(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL216954A0 publication Critical patent/IL216954A0/en
Publication of IL216954A publication Critical patent/IL216954A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL216954A 2009-06-22 2011-12-13 Protein folding by using oxidation-chemically controlled courtship mode IL216954A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21925709P 2009-06-22 2009-06-22
PCT/US2010/039390 WO2011005488A1 (en) 2009-06-22 2010-06-21 Refolding proteins using a chemically controlled redox state

Publications (2)

Publication Number Publication Date
IL216954A0 IL216954A0 (en) 2012-02-29
IL216954A true IL216954A (en) 2016-09-29

Family

ID=42710673

Family Applications (1)

Application Number Title Priority Date Filing Date
IL216954A IL216954A (en) 2009-06-22 2011-12-13 Protein folding by using oxidation-chemically controlled courtship mode

Country Status (15)

Country Link
US (5) US8952138B2 (enExample)
EP (2) EP3366692A1 (enExample)
JP (2) JP5808323B2 (enExample)
KR (1) KR101741859B1 (enExample)
CN (1) CN102482321B (enExample)
AU (1) AU2010270986B2 (enExample)
BR (1) BRPI1011940B8 (enExample)
CA (1) CA2765881C (enExample)
CL (1) CL2011003278A1 (enExample)
EA (1) EA020621B1 (enExample)
IL (1) IL216954A (enExample)
MX (1) MX2011013898A (enExample)
SG (1) SG176963A1 (enExample)
WO (1) WO2011005488A1 (enExample)
ZA (1) ZA201200512B (enExample)

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EP3660032B1 (en) 2009-06-25 2025-10-22 Amgen Inc. Capture purification processes for proteins expressed in a non-mammalian system
EP2417982A1 (en) * 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
US20150376228A1 (en) * 2013-02-22 2015-12-31 Biogenomics Limited Process for high efficiency refolding of recombinant proteins
WO2017019776A1 (en) * 2015-07-27 2017-02-02 Purdue Research Foundation Tandem folding methods to improve protein folding yield
EP3344651B1 (en) 2015-09-02 2022-03-02 Merck Sharp & Dohme Corp. A process for obtaining insulin with correctly formed disulfide bonds
IL285146B (en) * 2016-07-22 2022-09-01 Amgen Inc Methods for purifying proteins involving fc
CN108276470A (zh) * 2017-01-06 2018-07-13 深圳市新产业生物医学工程股份有限公司 细胞裂解液、提取胞内蛋白的方法、制备弓形虫抗原的方法和试剂盒
US11406576B2 (en) * 2017-04-10 2022-08-09 Kao Corporation Method for removing keratotic plugs
CN119881293A (zh) 2018-03-21 2025-04-25 沃特世科技公司 基于非抗体高亲和力的样品制备、吸附剂、装置和方法
KR20210110294A (ko) * 2018-11-07 2021-09-07 어플라이드 몰레큘라 트랜스포트 인크. 통과세포외배출용 전달 구조체 및 관련 방법
AU2021399935A1 (en) 2020-12-18 2023-06-29 Richter Gedeon Nyrt. Methods for the purification of refolded fc-peptide fusion protein
CN115894604B (zh) * 2022-12-16 2024-01-23 康日百奥生物科技(苏州)有限公司 重组蛋白澄清纯化方法

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Also Published As

Publication number Publication date
KR101741859B1 (ko) 2017-06-15
BRPI1011940B8 (pt) 2021-08-03
CA2765881A1 (en) 2011-01-13
AU2010270986B2 (en) 2014-05-22
CN102482321B (zh) 2015-06-17
US8952138B2 (en) 2015-02-10
JP2016028065A (ja) 2016-02-25
MX2011013898A (es) 2012-05-22
EP3366692A1 (en) 2018-08-29
JP6026608B2 (ja) 2016-11-16
EA020621B1 (ru) 2014-12-30
JP2012530782A (ja) 2012-12-06
CL2011003278A1 (es) 2012-11-09
BRPI1011940B1 (pt) 2021-07-20
CN102482321A (zh) 2012-05-30
EP2445923A1 (en) 2012-05-02
CA2765881C (en) 2016-08-02
IL216954A0 (en) 2012-02-29
SG176963A1 (en) 2012-02-28
WO2011005488A1 (en) 2011-01-13
JP5808323B2 (ja) 2015-11-10
BRPI1011940A2 (pt) 2016-11-22
AU2010270986A1 (en) 2012-01-19
EA201270015A1 (ru) 2012-05-30
US12269843B2 (en) 2025-04-08
US20190055281A1 (en) 2019-02-21
US20150315232A1 (en) 2015-11-05
KR20120052939A (ko) 2012-05-24
US20170145049A1 (en) 2017-05-25
US20150329586A1 (en) 2015-11-19
US9856287B2 (en) 2018-01-02
ZA201200512B (en) 2012-11-28
EP2445923B1 (en) 2018-09-05
US20100324269A1 (en) 2010-12-23

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