IL208794A0 - Oral administration of peripherally-acting opioid antagonists - Google Patents

Oral administration of peripherally-acting opioid antagonists

Info

Publication number
IL208794A0
IL208794A0 IL208794A IL20879410A IL208794A0 IL 208794 A0 IL208794 A0 IL 208794A0 IL 208794 A IL208794 A IL 208794A IL 20879410 A IL20879410 A IL 20879410A IL 208794 A0 IL208794 A0 IL 208794A0
Authority
IL
Israel
Prior art keywords
peripherally
oral administration
opioid antagonists
acting opioid
acting
Prior art date
Application number
IL208794A
Other languages
English (en)
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Publication of IL208794A0 publication Critical patent/IL208794A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL208794A 2008-05-07 2010-10-18 Oral administration of peripherally-acting opioid antagonists IL208794A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12686808P 2008-05-07 2008-05-07
PCT/US2009/002856 WO2009137086A1 (en) 2008-05-07 2009-05-07 Oral administration of peripherally-acting opioid antagonists

Publications (1)

Publication Number Publication Date
IL208794A0 true IL208794A0 (en) 2010-12-30

Family

ID=40888194

Family Applications (1)

Application Number Title Priority Date Filing Date
IL208794A IL208794A0 (en) 2008-05-07 2010-10-18 Oral administration of peripherally-acting opioid antagonists

Country Status (15)

Country Link
US (1) US20110160239A1 (enExample)
EP (1) EP2300009A1 (enExample)
JP (1) JP2011519930A (enExample)
KR (1) KR20110004425A (enExample)
CN (1) CN102014907A (enExample)
AU (1) AU2009244805B2 (enExample)
BR (1) BRPI0912219A2 (enExample)
CA (1) CA2723685C (enExample)
EA (1) EA201001643A1 (enExample)
IL (1) IL208794A0 (enExample)
MX (1) MX2010011727A (enExample)
MY (1) MY156913A (enExample)
NZ (1) NZ589733A (enExample)
WO (1) WO2009137086A1 (enExample)
ZA (1) ZA201007531B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2368554T3 (pl) 2003-04-08 2015-05-29 Progenics Pharm Inc Preparaty farmaceutyczne zawierające metylonaltrekson
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TWI605814B (zh) * 2010-03-11 2017-11-21 惠氏有限責任公司 甲基拿淬松(methylnaltrexone)之口服製劑及親脂性鹽
SI2621496T2 (sl) * 2010-09-30 2019-04-30 Astrazeneca Ab Kristalinični konjugat naloksol-PEG
WO2013096444A1 (en) * 2011-12-19 2013-06-27 Salix Pharmaceuticals, Ltd. Methods for treatment and prevention of opioid induced constipation using oral compositions of methylnaltrexone
CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
CN104546791A (zh) * 2013-10-16 2015-04-29 辽宁亿灵科创生物医药科技有限公司 一种阿片受体拮抗剂的固体制剂及其制备方法
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
AU2015253417B2 (en) 2014-04-28 2020-02-20 Dimerx, Inc. Pharmaceutically active dimers linked through phenolic hydroxyl groups
DK3169315T3 (da) 2014-07-17 2020-08-10 Pharmaceutical Manufacturing Res Services In Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
WO2017092638A1 (zh) * 2015-12-01 2017-06-08 江苏恒瑞医药股份有限公司 阿片样受体拮抗剂类衍生物、其制备方法及其在医药上的应用
CN107033154B (zh) * 2016-02-02 2020-02-04 上海瀚迈生物医药科技有限公司 阿片受体拮抗剂缀合物及其应用
CN109134479A (zh) * 2017-06-27 2019-01-04 石家庄蒎格医药科技有限公司 结晶聚乙二醇纳洛酮草酸盐及制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451806B2 (en) * 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
WO2001032180A2 (en) * 1999-11-01 2001-05-10 Rodeva Limited Composition for treatment of constipation and irritable bowel syndrome
US7056500B2 (en) * 2001-10-18 2006-06-06 Nektar Therapeutics Al, Corporation Polymer conjugates of opioid antagonists
CN1925875A (zh) * 2003-12-16 2007-03-07 尼克塔治疗亚拉巴马公司 化学改性的小分子
US20060182692A1 (en) * 2003-12-16 2006-08-17 Fishburn C S Chemically modified small molecules
ES2629766T3 (es) * 2006-04-21 2017-08-14 Nektar Therapeutics Reducción estereoselectiva de una morfinona
JP2010509227A (ja) * 2006-11-07 2010-03-25 ネクター セラピューティックス エイエル,コーポレイション オピオイド作動薬およびオピオイド拮抗薬の用量形態および同時投与

Also Published As

Publication number Publication date
KR20110004425A (ko) 2011-01-13
ZA201007531B (en) 2012-03-28
MY156913A (en) 2016-04-15
EA201001643A1 (ru) 2011-06-30
MX2010011727A (es) 2010-11-30
CA2723685C (en) 2016-09-27
WO2009137086A1 (en) 2009-11-12
NZ589733A (en) 2012-07-27
CN102014907A (zh) 2011-04-13
AU2009244805B2 (en) 2013-01-10
US20110160239A1 (en) 2011-06-30
BRPI0912219A2 (pt) 2015-10-06
AU2009244805A1 (en) 2009-11-12
JP2011519930A (ja) 2011-07-14
EP2300009A1 (en) 2011-03-30
CA2723685A1 (en) 2009-11-12

Similar Documents

Publication Publication Date Title
ZA201007531B (en) Oral administration of peripherally-acting opioid antagonists
ZA201008090B (en) Methods and compositions for oral administration of exenatide
IL218928A (en) Corticosteroids for oral administration
EP2395975A4 (en) ORAL PHARMACEUTICAL COMPOSITION OF DUTASTERIDE
ZA201101523B (en) Linaclotide-containing formulations for oral administration
IL211099A0 (en) Formulation for oral administration of proteins
IL206835A0 (en) Methods and compositions for oral administration of insulin
IL194734A0 (en) Pharmaceutical compositions containing opioid antagonists
IL211799A0 (en) Pharmaceutical compositions and related methods of delivery
IL221742A (en) Oral Pharmaceuticals Containing Debigtran Etxylate
PT2173345E (pt) Formulação oral de metadoxina
ZA201103791B (en) Oral dosage forms of bendamustine
ZA201105572B (en) Pharmaceutical composition for oral administration
PL2387389T3 (pl) Preparat do podawania przez śluzówkę jamy ustnej cząsteczek przeciwbólowych i/lub przeciwskurczowych
EP2263637A4 (en) MEDICINAL PREPARATION FOR ORAL ADMINISTRATION
IL208325A0 (en) Stabilizing lipis compositions for oral pharmaceutical agents
EP2337565A4 (en) STABLE SOLID ORAL CO DOSAGE FORMULATIONS
GB0822124D0 (en) Oral dosage form
IL202766A0 (en) Pharmaceutical combination of opioid and prostaglandin compound
HU0900482D0 (en) Pharmaceutical formulation for oral administration
ZA201102405B (en) Pharmaceutical composition for oral administration
HK1155379A (en) Oral administration of peripherally-acting opioid antagonists
EP2474294A4 (en) PREPARATION FOR ORAL ADMINISTRATION
IL219860A0 (en) Oral formulation for dexlansoprazole
PL2519261T3 (pl) Płynna kompozycja farmaceutyczna doustna nifedypiny