ZA201007531B - Oral administration of peripherally-acting opioid antagonists - Google Patents
Oral administration of peripherally-acting opioid antagonistsInfo
- Publication number
- ZA201007531B ZA201007531B ZA2010/07531A ZA201007531A ZA201007531B ZA 201007531 B ZA201007531 B ZA 201007531B ZA 2010/07531 A ZA2010/07531 A ZA 2010/07531A ZA 201007531 A ZA201007531 A ZA 201007531A ZA 201007531 B ZA201007531 B ZA 201007531B
- Authority
- ZA
- South Africa
- Prior art keywords
- peripherally
- oral administration
- opioid antagonists
- acting opioid
- acting
- Prior art date
Links
- 239000003887 narcotic antagonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12686808P | 2008-05-07 | 2008-05-07 | |
| PCT/US2009/002856 WO2009137086A1 (en) | 2008-05-07 | 2009-05-07 | Oral administration of peripherally-acting opioid antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201007531B true ZA201007531B (en) | 2012-03-28 |
Family
ID=40888194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/07531A ZA201007531B (en) | 2008-05-07 | 2010-10-21 | Oral administration of peripherally-acting opioid antagonists |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20110160239A1 (enExample) |
| EP (1) | EP2300009A1 (enExample) |
| JP (1) | JP2011519930A (enExample) |
| KR (1) | KR20110004425A (enExample) |
| CN (1) | CN102014907A (enExample) |
| AU (1) | AU2009244805B2 (enExample) |
| BR (1) | BRPI0912219A2 (enExample) |
| CA (1) | CA2723685C (enExample) |
| EA (1) | EA201001643A1 (enExample) |
| IL (1) | IL208794A0 (enExample) |
| MX (1) | MX2010011727A (enExample) |
| MY (1) | MY156913A (enExample) |
| NZ (1) | NZ589733A (enExample) |
| WO (1) | WO2009137086A1 (enExample) |
| ZA (1) | ZA201007531B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20150037T4 (hr) | 2003-04-08 | 2022-09-02 | Progenics Pharmaceuticals, Inc. | Farmaceutske formulacije koje sadrže metilnaltrekson |
| TWI489984B (zh) | 2006-08-04 | 2015-07-01 | Wyeth Corp | 用於非經腸道傳輸化合物之配方及其用途 |
| EA029096B1 (ru) * | 2010-03-11 | 2018-02-28 | Вайет Ллк | Твердая лекарственная форма для перорального введения, содержащая метилналтрексон |
| PE20140636A1 (es) | 2010-09-30 | 2014-06-18 | Astrazeneca Ab | Conjugado de naloxol-peg cristalino |
| AU2012359013A1 (en) * | 2011-12-19 | 2014-06-26 | Salix Pharmaceuticals, Ltd. | Methods for treatment and prevention of opioid induced constipation using oral compositions of methylnaltrexone |
| AU2014306759B2 (en) | 2013-08-12 | 2018-04-26 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| CN104546791A (zh) * | 2013-10-16 | 2015-04-29 | 辽宁亿灵科创生物医药科技有限公司 | 一种阿片受体拮抗剂的固体制剂及其制备方法 |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| HUE036084T2 (hu) | 2014-04-28 | 2018-06-28 | Orphomed Inc | Buprenorfin dimer és alkalmazása gasztrointesztinális rendellenességek kezelésénél |
| EP3169315B1 (en) | 2014-07-17 | 2020-06-24 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
| CN107406456B (zh) * | 2015-12-01 | 2019-08-30 | 江苏恒瑞医药股份有限公司 | 阿片样受体拮抗剂类衍生物、其制备方法及其在医药上的应用 |
| CN107033154B (zh) * | 2016-02-02 | 2020-02-04 | 上海瀚迈生物医药科技有限公司 | 阿片受体拮抗剂缀合物及其应用 |
| CN109134479A (zh) * | 2017-06-27 | 2019-01-04 | 石家庄蒎格医药科技有限公司 | 结晶聚乙二醇纳洛酮草酸盐及制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451806B2 (en) * | 1999-09-29 | 2002-09-17 | Adolor Corporation | Methods and compositions involving opioids and antagonists thereof |
| PT1225897E (pt) * | 1999-11-01 | 2005-01-31 | John Rhodes | Composicao para o tratamento da obstipacao e do sindroma do intestino irritavel |
| EP2236161A1 (en) * | 2001-10-18 | 2010-10-06 | Nektar Therapeutics | Polymer conjugates of opioid antagonists |
| US20060182692A1 (en) * | 2003-12-16 | 2006-08-17 | Fishburn C S | Chemically modified small molecules |
| HRP20140361T1 (hr) * | 2003-12-16 | 2014-05-23 | Nektar Therapeutics | Monodisperzne smjese pegiliranog naloksola |
| MX2008013594A (es) * | 2006-04-21 | 2009-01-16 | Nektar Therapeutics Al Corp | Reduccion estereoselectiva de una morfinona. |
| JP2010509227A (ja) * | 2006-11-07 | 2010-03-25 | ネクター セラピューティックス エイエル，コーポレイション | オピオイド作動薬およびオピオイド拮抗薬の用量形態および同時投与 |
-
2009
- 2009-05-07 KR KR1020107024868A patent/KR20110004425A/ko not_active Ceased
- 2009-05-07 CN CN2009801164862A patent/CN102014907A/zh active Pending
- 2009-05-07 MX MX2010011727A patent/MX2010011727A/es not_active Application Discontinuation
- 2009-05-07 NZ NZ589733A patent/NZ589733A/xx unknown
- 2009-05-07 WO PCT/US2009/002856 patent/WO2009137086A1/en not_active Ceased
- 2009-05-07 EP EP09743073A patent/EP2300009A1/en not_active Withdrawn
- 2009-05-07 BR BRPI0912219A patent/BRPI0912219A2/pt not_active Application Discontinuation
- 2009-05-07 US US12/991,229 patent/US20110160239A1/en not_active Abandoned
- 2009-05-07 JP JP2011508513A patent/JP2011519930A/ja active Pending
- 2009-05-07 AU AU2009244805A patent/AU2009244805B2/en active Active
- 2009-05-07 CA CA2723685A patent/CA2723685C/en active Active
- 2009-05-07 MY MYPI2010005212A patent/MY156913A/en unknown
- 2009-05-07 EA EA201001643A patent/EA201001643A1/ru unknown
-
2010
- 2010-10-18 IL IL208794A patent/IL208794A0/en unknown
- 2010-10-21 ZA ZA2010/07531A patent/ZA201007531B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009244805B2 (en) | 2013-01-10 |
| CA2723685A1 (en) | 2009-11-12 |
| US20110160239A1 (en) | 2011-06-30 |
| KR20110004425A (ko) | 2011-01-13 |
| EA201001643A1 (ru) | 2011-06-30 |
| CA2723685C (en) | 2016-09-27 |
| AU2009244805A1 (en) | 2009-11-12 |
| WO2009137086A1 (en) | 2009-11-12 |
| NZ589733A (en) | 2012-07-27 |
| MX2010011727A (es) | 2010-11-30 |
| BRPI0912219A2 (pt) | 2015-10-06 |
| MY156913A (en) | 2016-04-15 |
| EP2300009A1 (en) | 2011-03-30 |
| JP2011519930A (ja) | 2011-07-14 |
| IL208794A0 (en) | 2010-12-30 |
| CN102014907A (zh) | 2011-04-13 |
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