IL195201A - Composition for use in the treatment of a disease or condition caused or associated with hyperactive cholinergic nerve of the patient or exocrine glands in the patient and a method of reducing facial lines or wrinkles or removing asymmetry of the face - Google Patents

Composition for use in the treatment of a disease or condition caused or associated with hyperactive cholinergic nerve of the patient or exocrine glands in the patient and a method of reducing facial lines or wrinkles or removing asymmetry of the face

Info

Publication number
IL195201A
IL195201A IL195201A IL19520108A IL195201A IL 195201 A IL195201 A IL 195201A IL 195201 A IL195201 A IL 195201A IL 19520108 A IL19520108 A IL 19520108A IL 195201 A IL195201 A IL 195201A
Authority
IL
Israel
Prior art keywords
wrinkles
muscles
disease
skin
patient
Prior art date
Application number
IL195201A
Other languages
English (en)
Hebrew (he)
Other versions
IL195201A0 (en
Inventor
Matthias Marx
Susanne Grafe
Reiner Benecke
Dirk Dressler
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Matthias Marx
Susanne Grafe
Reiner Benecke
Dirk Dressler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38462381&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL195201(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merz Pharma Gmbh & Co Kgaa, Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of IL195201A0 publication Critical patent/IL195201A0/en
Publication of IL195201A publication Critical patent/IL195201A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893Botulinum neurotoxin (3.4.24.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/606Nucleosides; Nucleotides; Nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL195201A 2006-06-29 2008-11-10 Composition for use in the treatment of a disease or condition caused or associated with hyperactive cholinergic nerve of the patient or exocrine glands in the patient and a method of reducing facial lines or wrinkles or removing asymmetry of the face IL195201A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81775606P 2006-06-29 2006-06-29
PCT/EP2007/005754 WO2008000490A1 (en) 2006-06-29 2007-06-28 High frequency application of neurotoxic component of botulinum toxin

Publications (2)

Publication Number Publication Date
IL195201A0 IL195201A0 (en) 2009-08-03
IL195201A true IL195201A (en) 2015-11-30

Family

ID=38462381

Family Applications (1)

Application Number Title Priority Date Filing Date
IL195201A IL195201A (en) 2006-06-29 2008-11-10 Composition for use in the treatment of a disease or condition caused or associated with hyperactive cholinergic nerve of the patient or exocrine glands in the patient and a method of reducing facial lines or wrinkles or removing asymmetry of the face

Country Status (17)

Country Link
US (3) US8557255B2 (enExample)
EP (2) EP2032157A1 (enExample)
JP (2) JP5897784B2 (enExample)
KR (3) KR20140142377A (enExample)
CN (1) CN101460190A (enExample)
AR (1) AR061669A1 (enExample)
AU (1) AU2007264008B2 (enExample)
BR (1) BRPI0713061A2 (enExample)
CA (1) CA2654214C (enExample)
CL (1) CL2007001911A1 (enExample)
IL (1) IL195201A (enExample)
MX (1) MX2009000253A (enExample)
RU (1) RU2453333C2 (enExample)
TW (1) TWI519310B (enExample)
UY (1) UY30450A1 (enExample)
WO (1) WO2008000490A1 (enExample)
ZA (1) ZA200808491B (enExample)

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US20090204101A1 (en) * 2007-08-20 2009-08-13 Wortzman Mitchell S Method of applying an injectable filler
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US9161970B2 (en) * 2007-12-12 2015-10-20 Allergan, Inc. Dermal filler
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JP5746624B2 (ja) 2008-08-29 2015-07-08 メルツ・ファルマ・ゲーエムベーハー・ウント・コ・カーゲーアーアー 変化した持続性を有するクロストリジウム性神経毒
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EP2248518B1 (en) * 2009-04-17 2013-01-16 Merz Pharma GmbH & Co. KGaA Formulation for stabilizing proteins, peptides or mixtures thereof.
EP2246065A1 (en) 2009-04-29 2010-11-03 Merz Pharma GmbH & Co. KGaA Intrastriatal botulinum toxin therapy
WO2011023213A1 (en) * 2009-08-28 2011-03-03 Merz Pharma Gmbh & Co. Kgaa Modified chemodenervating agents
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KR101134146B1 (ko) 2010-05-31 2012-04-19 메덱스젠 주식회사 국소 근마비 효과를 갖는 비확산형 보툴리눔 독소와 그의 정제방법
EP2399601A1 (en) 2010-06-24 2011-12-28 Merz Pharma GmbH & Co. KGaA Botulinum toxin therapy
EP2627318B1 (en) 2010-10-12 2017-08-16 Merz Pharma GmbH & Co. KGaA Formulation suitable for stabilizing proteins, which is free of mammalian excipients
RU2454170C1 (ru) * 2011-02-21 2012-06-27 Федеральное государственное учреждение "Нижегородский научно-исследовательский институт травматологии и ортопедии" Министерства здравоохранения и социального развития Российской Федерации Способ лечения спастичности мышц у больных с позвоночно-спинномозговой травмой
MX370929B (es) 2012-10-28 2020-01-08 Revance Therapeutics Inc Composiciones y usos de las mismas para el tratamiento seguro de la rinitis.
RU2535115C1 (ru) 2013-05-15 2014-12-10 Бости Трейдинг Лтд Фармацевтический состав, содержащий нейротоксин ботулина
CN105658662B (zh) * 2013-07-30 2022-05-27 莫茨制药有限及两合公司 制备高纯度的肉毒杆菌毒素神经毒性组分的方法及其应用
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US10987411B1 (en) 2019-10-18 2021-04-27 Penland Foundation Treatment of chronic obstructive pulmonary disease using botulinum toxin
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US11925677B2 (en) 2021-07-12 2024-03-12 Penland Foundation Treatment of diabetes and chronic pancreatitis using botulinum toxin
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CA2654214C (en) 2023-07-04
US20080003241A1 (en) 2008-01-03
CA2654214A1 (en) 2008-01-03
CL2007001911A1 (es) 2008-03-14
UY30450A1 (es) 2009-04-30
CN101460190A (zh) 2009-06-17
WO2008000490A1 (en) 2008-01-03
RU2453333C2 (ru) 2012-06-20
US9095523B2 (en) 2015-08-04
KR20090027732A (ko) 2009-03-17
IL195201A0 (en) 2009-08-03
TWI519310B (zh) 2016-02-01
MX2009000253A (es) 2009-01-22
ZA200808491B (en) 2009-11-25
JP5897784B2 (ja) 2016-03-30
RU2009102848A (ru) 2010-08-10
US20140010803A1 (en) 2014-01-09
US20150290303A1 (en) 2015-10-15
US8557255B2 (en) 2013-10-15
KR20150126979A (ko) 2015-11-13
US9572871B2 (en) 2017-02-21
JP2009541396A (ja) 2009-11-26
BRPI0713061A2 (pt) 2012-04-10
TW200819140A (en) 2008-05-01
KR20140142377A (ko) 2014-12-11
AR061669A1 (es) 2008-09-10
EP2484373A1 (en) 2012-08-08
EP2032157A1 (en) 2009-03-11
AU2007264008A1 (en) 2008-01-03
AU2007264008B2 (en) 2012-06-28

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