IL194312A0 - Insulin derivative - Google Patents
Insulin derivativeInfo
- Publication number
- IL194312A0 IL194312A0 IL194312A IL19431208A IL194312A0 IL 194312 A0 IL194312 A0 IL 194312A0 IL 194312 A IL194312 A IL 194312A IL 19431208 A IL19431208 A IL 19431208A IL 194312 A0 IL194312 A0 IL 194312A0
- Authority
- IL
- Israel
- Prior art keywords
- insulin derivative
- insulin
- derivative
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 1
- 239000004026 insulin derivative Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06113709 | 2006-05-09 | ||
| EP06118260 | 2006-08-01 | ||
| PCT/EP2007/054444 WO2007128817A2 (en) | 2006-05-09 | 2007-05-08 | Insulin derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL194312A0 true IL194312A0 (en) | 2011-08-01 |
Family
ID=38668119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL194312A IL194312A0 (en) | 2006-05-09 | 2008-09-24 | Insulin derivative |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8933021B2 (enExample) |
| EP (2) | EP2386572B1 (enExample) |
| JP (1) | JP5269767B2 (enExample) |
| KR (1) | KR101441444B1 (enExample) |
| AU (1) | AU2007247109B2 (enExample) |
| BR (1) | BRPI0712041A2 (enExample) |
| CA (1) | CA2649235A1 (enExample) |
| ES (2) | ES2395738T3 (enExample) |
| IL (1) | IL194312A0 (enExample) |
| MX (1) | MX2008014061A (enExample) |
| NO (1) | NO20085056L (enExample) |
| RU (1) | RU2451029C2 (enExample) |
| WO (1) | WO2007128817A2 (enExample) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2107069B1 (en) * | 2003-08-05 | 2013-01-16 | Novo Nordisk A/S | Novel insulin derivatives |
| EP1846447B1 (en) * | 2005-02-02 | 2013-08-21 | Novo Nordisk A/S | Insulin derivatives |
| EP2256130B1 (en) | 2005-02-02 | 2013-09-25 | Novo Nordisk A/S | Novel insulin derivatives |
| EP2505593A1 (en) * | 2005-12-28 | 2012-10-03 | Novo Nordisk A/S | Compositions comprising an acylated insulin and zinc and method of making the said compositions |
| DE602007009496D1 (de) | 2006-02-27 | 2010-11-11 | Novo Nordisk As | Insulinderivate |
| EP2024390B1 (en) | 2006-05-09 | 2015-08-19 | Novo Nordisk A/S | Insulin derivative |
| EP2074141B1 (en) | 2006-09-22 | 2016-08-10 | Novo Nordisk A/S | Protease resistant insulin analogues |
| US20120214963A1 (en) * | 2011-02-23 | 2012-08-23 | Elona Biotechnologies | Aspart proinsulin compositions and methods of producing aspart insulin analogs therefrom |
| US10100098B2 (en) | 2006-12-13 | 2018-10-16 | Stelis Biopharma Private Limited | Insulin production methods and proinsulin constructs |
| WO2008132224A2 (en) | 2007-04-30 | 2008-11-06 | Novo Nordisk A/S | Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein |
| CN101677947B (zh) | 2007-06-13 | 2013-07-17 | 诺沃-诺迪斯克有限公司 | 包含胰岛素衍生物的药物制剂 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| CN101932601B (zh) * | 2007-11-08 | 2016-08-03 | 诺沃-诺迪斯克有限公司 | 胰岛素衍生物 |
| CA2705821A1 (en) | 2007-11-16 | 2009-05-22 | Novo Nordisk A/S | Pharmaceutical compositions containing insulin and an insulinotropic peptide |
| CN101970477B (zh) | 2008-03-14 | 2014-12-31 | 诺沃-诺迪斯克有限公司 | 蛋白酶稳定的胰岛素类似物 |
| PT2910570T (pt) | 2008-03-18 | 2017-01-24 | Novo Nordisk As | Análogos de insulina acilados, estabilizados contra proteases |
| AU2009309623B9 (en) * | 2008-10-30 | 2014-10-02 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections with less than daily injection frequency |
| JP2013514322A (ja) | 2009-12-16 | 2013-04-25 | ノヴォ ノルディスク アー/エス | 修飾されたn末端を有するglp−1受容体アゴニスト化合物 |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| DE102010015123A1 (de) | 2010-04-16 | 2011-10-20 | Sanofi-Aventis Deutschland Gmbh | Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| RU2013123515A (ru) | 2010-10-27 | 2014-12-10 | Ново Нордиск А/С | Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами |
| EP2632478B1 (en) * | 2010-10-27 | 2019-07-24 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections administered with varying injection intervals |
| PL3326620T3 (pl) | 2010-12-16 | 2020-08-24 | Novo Nordisk A/S | Kompozycje stałe zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino)kaprylowego |
| MX342922B (es) * | 2011-02-01 | 2016-10-19 | Novo Nordisk As | Purificacion de insulina. |
| US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| ES2712945T3 (es) * | 2011-04-12 | 2019-05-16 | Novo Nordisk As | Derivados de GLP-1 doblemente acilados |
| BR112013026195A2 (pt) | 2011-04-12 | 2016-11-29 | Novo Nordisk As | derivados de glp-1 duplamente acilados |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| HUE062740T2 (hu) | 2012-03-22 | 2023-12-28 | Novo Nordisk As | GLP-1 peptidek készítményei és elõállításuk |
| DK2827845T3 (en) | 2012-03-22 | 2019-04-01 | Novo Nordisk As | COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF |
| BR112014025132A2 (pt) | 2012-04-11 | 2017-07-11 | Novo Nordisk As | formulações de insulina |
| US9884094B2 (en) | 2012-05-01 | 2018-02-06 | Novo Nordisk A/S | Method of treating diabetes mellitus |
| US9993430B2 (en) | 2012-06-20 | 2018-06-12 | Novo Nordisk A/S | Tablet formulation comprising semaglutide and a delivery agent |
| US9457096B2 (en) | 2012-07-06 | 2016-10-04 | Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Concet) | Protozoan variant-specific surface proteins (VSP) as carriers for oral drug delivery |
| TWI641381B (zh) * | 2013-02-04 | 2018-11-21 | 法商賽諾菲公司 | 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物 |
| WO2014177623A1 (en) | 2013-04-30 | 2014-11-06 | Novo Nordisk A/S | Novel administration regime |
| PT2991671T (pt) | 2013-05-02 | 2018-11-05 | Novo Nordisk As | Dosagem oral de compostos de glp-1 |
| PT3055325T (pt) | 2013-10-07 | 2018-04-06 | Novo Nordisk As | Novo derivado de um análogo de insulina |
| AU2015205624A1 (en) | 2014-01-09 | 2016-07-14 | Sanofi | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives |
| AR099569A1 (es) | 2014-02-28 | 2016-08-03 | Novo Nordisk As | Derivados de insulina y los usos médicos de estos |
| PT3554534T (pt) | 2016-12-16 | 2021-11-05 | Novo Nordisk As | Composições farmacêuticas contendo insulina |
| SG11202006595RA (en) | 2018-02-02 | 2020-08-28 | Novo Nordisk As | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
| US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
| BR112021011050A2 (pt) | 2018-12-11 | 2021-08-31 | Sanofi | Ligante peptídico |
| US12343383B2 (en) | 2019-07-12 | 2025-07-01 | Novo Nordisk A/S | High concentration insulin formulation |
| US20240239862A1 (en) * | 2019-12-30 | 2024-07-18 | Gan & Lee Pharmaceuticals Co., Ltd. | Insulin Derivative |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3528960A (en) * | 1968-10-07 | 1970-09-15 | Lilly Co Eli | N-carboxyaroyl insulins |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
| NZ222907A (en) | 1986-12-16 | 1990-08-28 | Novo Industri As | Preparation for intranasal administration containing a phospholipid absorption enhancing system |
| JPH01254699A (ja) | 1988-04-05 | 1989-10-11 | Kodama Kk | インスリン誘導体及びその用途 |
| WO1990007522A1 (en) | 1988-12-23 | 1990-07-12 | Novo Nordisk A/S | Human insulin analogues |
| IL93282A (en) | 1989-02-09 | 1995-08-31 | Lilly Co Eli | Insulin analogues |
| JP3018463B2 (ja) * | 1989-10-19 | 2000-03-13 | 日本油脂株式会社 | グルコース応答性薬物放出複合体 |
| DK10191D0 (da) * | 1991-01-22 | 1991-01-22 | Novo Nordisk As | Hidtil ukendte peptider |
| US5359030A (en) * | 1993-05-10 | 1994-10-25 | Protein Delivery, Inc. | Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same |
| US6869930B1 (en) | 1993-09-17 | 2005-03-22 | Novo Nordisk A/S | Acylated insulin |
| US6011007A (en) | 1993-09-17 | 2000-01-04 | Novo Nordisk A/S | Acylated insulin |
| DE122004000035I2 (de) | 1993-09-17 | 2009-08-06 | Novo Nordisk As | Acyliertes insulin |
| US5693609A (en) * | 1994-11-17 | 1997-12-02 | Eli Lilly And Company | Acylated insulin analogs |
| AU720966B2 (en) * | 1995-03-17 | 2000-06-22 | Novo Nordisk A/S | Insulin derivatives |
| US6451970B1 (en) | 1996-02-21 | 2002-09-17 | Novo Nordisk A/S | Peptide derivatives |
| JP3300368B2 (ja) * | 1996-07-11 | 2002-07-08 | ノボ ノルディスク アクティーゼルスカブ | 選択的アシル化方法 |
| US5905140A (en) | 1996-07-11 | 1999-05-18 | Novo Nordisk A/S, Novo Alle | Selective acylation method |
| US5898067A (en) | 1997-02-07 | 1999-04-27 | Novo Nordisk A/S | Crystallization of proteins |
| ZA989744B (en) | 1997-10-31 | 2000-04-26 | Lilly Co Eli | Method for administering acylated insulin. |
| DE69924232D1 (de) | 1998-01-09 | 2005-04-21 | Novo Nordisk As | Stabilisierte insulin-zubereitungen |
| JP2004537580A (ja) | 2001-08-10 | 2004-12-16 | エピックス メディカル, インコーポレイテッド | 延長された循環半減期を有するポリペプチド結合体 |
| WO2003075950A1 (en) | 2002-03-13 | 2003-09-18 | Novo Nordisk A/S | Minimising body weight gain in insulin treatment |
| US20040138099A1 (en) | 2002-11-29 | 2004-07-15 | Draeger Eberhard Kurt | Insulin administration regimens for the treatment of subjects with diabetes |
| WO2005005477A2 (en) * | 2003-07-11 | 2005-01-20 | Novo Nordisk A/S | Stabilised insulin compositions |
| AU2004261319B2 (en) * | 2003-07-25 | 2010-12-23 | Conjuchem Biotechnologies Inc. | Long lasting insulin derivatives and methods thereof |
| EP2107069B1 (en) | 2003-08-05 | 2013-01-16 | Novo Nordisk A/S | Novel insulin derivatives |
| CA2546243A1 (en) | 2003-11-14 | 2005-05-26 | University Of Tennessee Research Corporation | The mycolactone locus : an assembly line for producing novel polyketides, with therapeutic and prophylatic uses |
| EP1687428A1 (en) | 2003-11-14 | 2006-08-09 | Novo Nordisk A/S | Processes for making acylated insulin |
| US20070221884A1 (en) | 2004-07-16 | 2007-09-27 | Holger Hoppe | Liminescent Silicon Oxide Flakes |
| WO2006008238A1 (en) | 2004-07-16 | 2006-01-26 | Novo Nordisk A/S | Method for selective acylation |
| EP2256130B1 (en) | 2005-02-02 | 2013-09-25 | Novo Nordisk A/S | Novel insulin derivatives |
| EP1846447B1 (en) | 2005-02-02 | 2013-08-21 | Novo Nordisk A/S | Insulin derivatives |
| DE102005062618B4 (de) | 2005-12-23 | 2008-05-08 | Carl Zeiss Smt Ag | Optische Abbildungseinrichtung und Abbildungsverfahren mit Bestimmung von Abbildungsfehlern |
| EP2505593A1 (en) * | 2005-12-28 | 2012-10-03 | Novo Nordisk A/S | Compositions comprising an acylated insulin and zinc and method of making the said compositions |
| DE602007009496D1 (de) * | 2006-02-27 | 2010-11-11 | Novo Nordisk As | Insulinderivate |
| EP1996223A1 (en) * | 2006-03-13 | 2008-12-03 | Novo Nordisk A/S | Acylated single chain insulin |
| EP2024390B1 (en) * | 2006-05-09 | 2015-08-19 | Novo Nordisk A/S | Insulin derivative |
| CN101677947B (zh) | 2007-06-13 | 2013-07-17 | 诺沃-诺迪斯克有限公司 | 包含胰岛素衍生物的药物制剂 |
| CN101932601B (zh) | 2007-11-08 | 2016-08-03 | 诺沃-诺迪斯克有限公司 | 胰岛素衍生物 |
| WO2009060072A1 (de) | 2007-11-09 | 2009-05-14 | Mann+Hummel Gmbh | Filterelement für flüssigkeitsfilter und flüssigkeitsfilter |
| AU2009309623B9 (en) | 2008-10-30 | 2014-10-02 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections with less than daily injection frequency |
| US20130143803A1 (en) | 2010-05-10 | 2013-06-06 | Novo Nordisk A/S | Process for the Preparation of Insulin-Zinc Complexes |
| WO2011141408A2 (de) | 2010-05-10 | 2011-11-17 | Basf Se | Thermoplastisches polyurethan enthaltend glycerin, das mit mindestens einer aliphatischen carbonsäure verestert ist als weichmacher |
-
2007
- 2007-05-08 MX MX2008014061A patent/MX2008014061A/es active IP Right Grant
- 2007-05-08 ES ES07728897T patent/ES2395738T3/es active Active
- 2007-05-08 EP EP11160404.7A patent/EP2386572B1/en not_active Not-in-force
- 2007-05-08 KR KR1020087027649A patent/KR101441444B1/ko not_active Expired - Fee Related
- 2007-05-08 ES ES11160404.7T patent/ES2548393T3/es active Active
- 2007-05-08 AU AU2007247109A patent/AU2007247109B2/en not_active Ceased
- 2007-05-08 US US12/297,911 patent/US8933021B2/en not_active Expired - Fee Related
- 2007-05-08 JP JP2009508373A patent/JP5269767B2/ja not_active Expired - Fee Related
- 2007-05-08 WO PCT/EP2007/054444 patent/WO2007128817A2/en not_active Ceased
- 2007-05-08 BR BRPI0712041-9A patent/BRPI0712041A2/pt not_active IP Right Cessation
- 2007-05-08 CA CA002649235A patent/CA2649235A1/en not_active Withdrawn
- 2007-05-08 RU RU2008143668/04A patent/RU2451029C2/ru not_active IP Right Cessation
- 2007-05-08 EP EP07728897A patent/EP2015770B1/en not_active Not-in-force
-
2008
- 2008-09-24 IL IL194312A patent/IL194312A0/en unknown
- 2008-12-03 NO NO20085056A patent/NO20085056L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2008014061A (es) | 2008-11-14 |
| BRPI0712041A2 (pt) | 2011-12-27 |
| WO2007128817A2 (en) | 2007-11-15 |
| JP2009536179A (ja) | 2009-10-08 |
| EP2386572B1 (en) | 2015-07-08 |
| WO2007128817A3 (en) | 2008-03-06 |
| EP2386572A1 (en) | 2011-11-16 |
| NO20085056L (no) | 2008-12-03 |
| RU2008143668A (ru) | 2010-06-20 |
| CA2649235A1 (en) | 2007-11-15 |
| KR20090018906A (ko) | 2009-02-24 |
| US8933021B2 (en) | 2015-01-13 |
| KR101441444B1 (ko) | 2014-09-18 |
| US20090239785A1 (en) | 2009-09-24 |
| EP2015770B1 (en) | 2012-09-26 |
| AU2007247109B2 (en) | 2012-03-15 |
| ES2395738T3 (es) | 2013-02-14 |
| RU2451029C2 (ru) | 2012-05-20 |
| AU2007247109A1 (en) | 2007-11-15 |
| ES2548393T3 (es) | 2015-10-16 |
| JP5269767B2 (ja) | 2013-08-21 |
| EP2015770A2 (en) | 2009-01-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL194312A0 (en) | Insulin derivative | |
| GB2445090B (en) | Improved autoinjector | |
| GB2434317B (en) | Improved autoinjector | |
| LT2017278T (lt) | Dihidropirazolopirimidinono darinys | |
| EP2009005A4 (en) | AZOLECARBOXAMIDE DERIVATIVE | |
| IL196543A0 (en) | Pyridizinone derivatives | |
| IL193641A0 (en) | Spiroindolinone derivatives | |
| IL195013A0 (en) | Pyridopyrimidinone derivatives | |
| IL198319A0 (en) | Spiroindolinone derivatives | |
| IL195422A0 (en) | 2-pyrazinecarboxamide derivatives | |
| IL192401A0 (en) | Indol-3-yl-carbonyl-spiro-piperidine derivatives | |
| IL196364A0 (en) | Aminoindazolylurea derivatives | |
| IL198059A0 (en) | 2-aminocarbonyl-pyridine derivatives | |
| GB2436526B (en) | Syringe | |
| IL193211A0 (en) | Indazole-heteroaryl derivatives | |
| IL198645A0 (en) | 5-hydroxymethyl-oxazolidin-2-one derivatives | |
| IL197152A0 (en) | 5-phenyl-nicotinamide derivatives | |
| GB0603926D0 (en) | Syringes | |
| EP2015810A4 (en) | IMPROVED SYRINGE | |
| EP2035031A4 (en) | INSULIN COMPOSITION | |
| EP2060563A4 (en) | CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE | |
| GB0608046D0 (en) | Syringe | |
| ZA200807460B (en) | Spiroindolinone derivatives | |
| IL197239A0 (en) | Phenyloxyaniline derivatives | |
| ZA200808100B (en) | Insulin derivative |