IL166527A0 - Macrolide compounds endowed with antiinflammatory activity - Google Patents

Macrolide compounds endowed with antiinflammatory activity

Info

Publication number
IL166527A0
IL166527A0 IL16652705A IL16652705A IL166527A0 IL 166527 A0 IL166527 A0 IL 166527A0 IL 16652705 A IL16652705 A IL 16652705A IL 16652705 A IL16652705 A IL 16652705A IL 166527 A0 IL166527 A0 IL 166527A0
Authority
IL
Israel
Prior art keywords
antiinflammatory activity
macrolide compounds
compounds endowed
macrolide
endowed
Prior art date
Application number
IL16652705A
Other languages
English (en)
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of IL166527A0 publication Critical patent/IL166527A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL16652705A 2002-08-01 2005-01-27 Macrolide compounds endowed with antiinflammatory activity IL166527A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001726A ITMI20021726A1 (it) 2002-08-01 2002-08-01 Macrolidi ad attivita' antiinfiammatoria.
PCT/EP2003/008448 WO2004013153A2 (en) 2002-08-01 2003-07-29 Macrolide compounds endowed with antiinflammatory activity

Publications (1)

Publication Number Publication Date
IL166527A0 true IL166527A0 (en) 2006-01-15

Family

ID=31198615

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16652705A IL166527A0 (en) 2002-08-01 2005-01-27 Macrolide compounds endowed with antiinflammatory activity

Country Status (18)

Country Link
US (2) US7488811B2 (de)
EP (2) EP1529053B1 (de)
JP (1) JP4589110B2 (de)
KR (1) KR101051369B1 (de)
CN (1) CN100335491C (de)
AT (1) ATE509938T1 (de)
AU (1) AU2003269861B2 (de)
BR (1) BR0313162A (de)
CA (1) CA2493995C (de)
CO (1) CO5720000A2 (de)
ES (1) ES2364647T3 (de)
HR (1) HRP20050195B1 (de)
IL (1) IL166527A0 (de)
IT (1) ITMI20021726A1 (de)
NZ (1) NZ537992A (de)
PT (1) PT1529053E (de)
RU (1) RU2330856C2 (de)
WO (1) WO2004013153A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
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ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ES2316805T3 (es) * 2002-08-29 2009-04-16 Pfizer Inc. Compuestos motilidos.
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
US7407941B2 (en) 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
ITMI20040124A1 (it) * 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
CN1950388A (zh) * 2004-02-27 2007-04-18 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
EP2716647A3 (de) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Makrocyclische Verbindungen Und Verfahren Zu Deren Herstellung Und Anwendung
ES2317527T3 (es) * 2005-01-13 2009-04-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Decladinosil-macrolidos que presentan actividad anti-inflamatoria.
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
CN101291947B (zh) * 2005-07-06 2012-08-22 萨宝公司 具有抗炎活性的大环内酯化合物的晶形
US8470985B2 (en) 2005-08-24 2013-06-25 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
US8278281B2 (en) * 2005-08-24 2012-10-02 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
NZ567088A (en) 2005-10-19 2012-06-29 Teva Pharma Crystals of laquinimod sodium, and process for the manufacture thereof
NZ568763A (en) * 2005-12-08 2010-04-30 Pfizer Method for demethylating the 3'-dimethylamino group of erythromycin compounds
US8124744B2 (en) 2006-05-01 2012-02-28 Taisho Pharmaceutical Co., Ltd. Macrolide derivatives
WO2008106226A2 (en) * 2007-02-28 2008-09-04 Rib-X Pharmaceuticals, Inc. Macrolide compounds and methods of making and using the same
US8410065B2 (en) 2008-02-08 2013-04-02 Basilea Pharmaceutica Ag Macrolides and their use
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides
WO2010086350A1 (en) 2009-01-30 2010-08-05 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. 9-deoxo- 9a-methyl- 9a- aza- 9a-h0m0erythr0mycin a derivatives for the treatment of neutrophil dominated inflammatory diseases
TW201038277A (en) 2009-01-30 2010-11-01 Glaxosmithkline Zagreb Anti-inflammatory macrolide
WO2011018510A1 (en) 2009-08-13 2011-02-17 Basilea Pharmaceutica Ag New macrolides and their use
WO2011131749A1 (en) 2010-04-23 2011-10-27 Glaxo Group Limited New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases
MX2015005632A (es) 2012-11-07 2016-02-05 Teva Pharma Sales de amina de laquinimod.
NZ630427A (en) 2013-03-14 2017-06-30 Teva Pharma Crystals of laquinimod sodium and improved process for the manufacture thereof
WO2014166503A1 (en) * 2013-04-10 2014-10-16 Probiotic Pharmaceuticals Aps Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
EP4051687A4 (de) * 2020-01-08 2022-12-21 Beijing Continent Pharmaceuticals Co., Ltd. Makrolidverbindung und ihre verwendung zur behandlung von chronischer atemwegserkrankung

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GB1100504A (en) * 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US3623784A (en) * 1969-11-05 1971-11-30 Massey Ferguson Ind Ltd Cabinet joint structure
US3725385A (en) 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US3923784A (en) * 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
EP0184921A3 (de) * 1984-12-08 1986-10-29 Beecham Group Plc Erythromycinderivate
EP0254534A3 (de) 1986-07-24 1991-04-17 William S. Robinson Erythromycin-Derivate und Zusammensetzungen und ihre Verwendung, um Virusreplikation und Krankheiten zu Inhibieren
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
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US6096715A (en) * 1993-05-07 2000-08-01 City Of Hope Chimeric DNA-RNA catalytic sequences
WO1996004919A1 (fr) 1994-08-12 1996-02-22 Taisho Pharmaceutical Co., Ltd. Inhibiteur de production de l'interleukine-5
CN1159756A (zh) 1994-08-12 1997-09-17 大正制药株式会社 抑制白细胞介素5的产生的抑制剂
IT1276901B1 (it) 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
FR2735694B1 (fr) * 1995-06-20 1997-08-08 Roussel Uclaf Le cladinose a titre de medicament et les compositions pharmaceutiques les renfermant
FR2738571B1 (fr) * 1995-09-11 1997-10-17 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
WO1997017357A1 (en) * 1995-11-08 1997-05-15 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins a and b
FR2745290B1 (fr) * 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
ZA987689B (en) * 1997-09-02 1999-02-24 Abbott Lab 3-descladinose 6-O substituted erythromycin derivatives
AU737310B2 (en) 1997-09-30 2001-08-16 Abbott Laboratories 3'-n-modified 6-o-substituted erythromycin ketolide derivatives having antibacterial activity
JPH11236395A (ja) * 1997-12-11 1999-08-31 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
US5892008A (en) * 1997-12-16 1999-04-06 Abbott Laboratories Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives
DK0941998T3 (da) * 1998-03-03 2004-09-20 Pfizer Prod Inc 3,6-ketalmakrolidantibiotika
IT1306205B1 (it) 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
DE19910159A1 (de) 1999-02-26 2000-09-14 Rosemarie Heis Spezifische lgY-Eidotterantikörper, ihre Gewinnung und ihre Verwendung
JP2000351793A (ja) * 1999-06-09 2000-12-19 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
JP2001181294A (ja) * 1999-12-27 2001-07-03 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US20060043226A1 (en) * 2004-08-24 2006-03-02 Keith Roozeboom Apparatus and method for grinding with staggered cutters
US7096915B2 (en) * 2004-11-05 2006-08-29 Hsiu-Man Yu Chen Tape-roll supporting device

Also Published As

Publication number Publication date
EP1529053A2 (de) 2005-05-11
ES2364647T3 (es) 2011-09-08
KR101051369B1 (ko) 2011-07-22
CN1678620A (zh) 2005-10-05
NZ537992A (en) 2007-11-30
JP2005538998A (ja) 2005-12-22
US7488811B2 (en) 2009-02-10
RU2005105592A (ru) 2005-08-27
PT1529053E (pt) 2011-07-05
WO2004013153A3 (en) 2004-04-08
HRP20050195B1 (hr) 2013-10-25
US7704960B2 (en) 2010-04-27
WO2004013153A2 (en) 2004-02-12
ITMI20021726A1 (it) 2004-02-02
US20090054357A1 (en) 2009-02-26
RU2330856C2 (ru) 2008-08-10
US20060058246A1 (en) 2006-03-16
EP1529053B1 (de) 2011-05-18
AU2003269861B2 (en) 2010-01-21
EP2258708A1 (de) 2010-12-08
BR0313162A (pt) 2005-07-05
JP4589110B2 (ja) 2010-12-01
CO5720000A2 (es) 2007-01-31
ATE509938T1 (de) 2011-06-15
CN100335491C (zh) 2007-09-05
CA2493995A1 (en) 2004-02-12
AU2003269861A1 (en) 2004-02-23
KR20050037567A (ko) 2005-04-22
HRP20050195A2 (en) 2005-12-31
CA2493995C (en) 2011-01-04

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees