IL166307A0 - Preparation of 1h-imidazoÄ4,5-cÜquinolin-4-amines via novel 1h-imidazoÄ4,5-cÜquinolin-4-cyano and 1h-imidazo Ä4,5-cÜquinolin-4-cyano and 1h-imidazoÄ4,5-cÜquinolin-4-carboxamide intermediates - Google Patents
Preparation of 1h-imidazoÄ4,5-cÜquinolin-4-amines via novel 1h-imidazoÄ4,5-cÜquinolin-4-cyano and 1h-imidazo Ä4,5-cÜquinolin-4-cyano and 1h-imidazoÄ4,5-cÜquinolin-4-carboxamide intermediatesInfo
- Publication number
- IL166307A0 IL166307A0 IL16630703A IL16630703A IL166307A0 IL 166307 A0 IL166307 A0 IL 166307A0 IL 16630703 A IL16630703 A IL 16630703A IL 16630703 A IL16630703 A IL 16630703A IL 166307 A0 IL166307 A0 IL 166307A0
- Authority
- IL
- Israel
- Prior art keywords
- cüquinolin
- imidazoä4
- cyano
- imidazo
- quinoline
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 6
- 238000002360 preparation method Methods 0.000 title abstract 2
- UQUPJGMZYBOGDJ-UHFFFAOYSA-N 3h-imidazo[4,5-c]quinoline-4-carboxamide Chemical compound NC(=O)C1=NC2=CC=CC=C2C2=C1N=CN2 UQUPJGMZYBOGDJ-UHFFFAOYSA-N 0.000 abstract 2
- DOUYETYNHWVLEO-UHFFFAOYSA-N imiquimod Chemical compound C1=CC=CC2=C3N(CC(C)C)C=NC3=C(N)N=C21 DOUYETYNHWVLEO-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- ZDKGVDBUWDUSTO-UHFFFAOYSA-N 1-(2-methylpropyl)imidazo[4,5-c]quinoline-4-carboxamide Chemical compound C1=CC=CC2=C3N(CC(C)C)C=NC3=C(C(N)=O)N=C21 ZDKGVDBUWDUSTO-UHFFFAOYSA-N 0.000 abstract 1
- ITIRVXDSMXFTPW-UHFFFAOYSA-N 1H-imidazo[4,5-c]quinoline Chemical compound C1=CC=CC2=C(NC=N3)C3=CN=C21 ITIRVXDSMXFTPW-UHFFFAOYSA-N 0.000 abstract 1
- HQBUPOAKJGJGCD-UHFFFAOYSA-N 3h-imidazo[4,5-c]quinolin-4-amine Chemical class NC1=NC2=CC=CC=C2C2=C1N=CN2 HQBUPOAKJGJGCD-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229960002751 imiquimod Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39859202P | 2002-07-26 | 2002-07-26 | |
| PCT/US2003/023543 WO2004011462A1 (en) | 2002-07-26 | 2003-07-28 | Preparation of 1h-imidazo [4,5-c] quinolin-4-amines via novel 1h-imidazo [4,5-c] quinolin-4-cyano and 1h-imidazo [4,5-c] quinolin-4-carboxamide intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL166307A0 true IL166307A0 (en) | 2006-01-15 |
Family
ID=31188428
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16630703A IL166307A0 (en) | 2002-07-26 | 2003-07-28 | Preparation of 1h-imidazoÄ4,5-cÜquinolin-4-amines via novel 1h-imidazoÄ4,5-cÜquinolin-4-cyano and 1h-imidazo Ä4,5-cÜquinolin-4-cyano and 1h-imidazoÄ4,5-cÜquinolin-4-carboxamide intermediates |
| IL166307A IL166307A (en) | 2002-07-26 | 2005-01-16 | Preparation of 1h-imidazo[4,5-c]quinolin-4-amines via 1h-imidazo [4,5-c]quinolin-4-cyano and 1h-imidazo [4,5-c]quinolin-4-carboxamide intermediates |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL166307A IL166307A (en) | 2002-07-26 | 2005-01-16 | Preparation of 1h-imidazo[4,5-c]quinolin-4-amines via 1h-imidazo [4,5-c]quinolin-4-cyano and 1h-imidazo [4,5-c]quinolin-4-carboxamide intermediates |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US6841678B2 (de) |
| EP (1) | EP1539752B1 (de) |
| JP (1) | JP2005537287A (de) |
| KR (1) | KR20050030958A (de) |
| CN (1) | CN100372847C (de) |
| AT (1) | ATE357445T1 (de) |
| AU (1) | AU2003254221A1 (de) |
| CA (1) | CA2493158A1 (de) |
| DE (1) | DE60312701T8 (de) |
| DK (1) | DK1539752T3 (de) |
| ES (1) | ES2282691T3 (de) |
| HR (1) | HRP20050183A2 (de) |
| IL (2) | IL166307A0 (de) |
| MX (1) | MXPA05000997A (de) |
| PL (1) | PL374866A1 (de) |
| PT (1) | PT1539752E (de) |
| SI (1) | SI1539752T1 (de) |
| WO (1) | WO2004011462A1 (de) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6677347B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamido ether substituted imidazoquinolines |
| CA2466752C (en) * | 2001-11-13 | 2011-05-24 | John C. Barton | Touchless automatic fiber optic beverage/ice dispenser |
| JP2005538057A (ja) | 2002-06-07 | 2005-12-15 | スリーエム イノベイティブ プロパティズ カンパニー | エーテル置換イミダゾピリジン |
| PT1539752E (pt) * | 2002-07-26 | 2007-05-31 | Teva Gyogyszergyar Zartkoeruen | Preparação de 1h-imidazo [4,5-c] quinolina-4-aminas via novos intermediários imidazo [4,5-c] quinolina-4-ciano e 1h-imidazo [4,5-c] quinolina-4-carboxamida |
| US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
| WO2004096144A2 (en) * | 2003-04-28 | 2004-11-11 | 3M Innovative Properties Company | Compositions and methods for induction of opioid receptors |
| BRPI0413558A (pt) * | 2003-08-12 | 2006-10-17 | 3M Innovative Properties Co | compostos contendo imidazo substituìdo por hidroxilamina |
| US7799800B2 (en) * | 2003-08-14 | 2010-09-21 | 3M Innovative Properties Company | Lipid-modified immune response modifiers |
| AU2004268625B2 (en) * | 2003-08-27 | 2011-03-31 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
| AU2004270201A1 (en) * | 2003-09-05 | 2005-03-17 | 3M Innovative Properties Company | Treatment for CD5+ B cell lymphoma |
| US7544697B2 (en) * | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| AR046046A1 (es) | 2003-10-03 | 2005-11-23 | 3M Innovative Properties Co | Imidazoquinolinas alcoxi sustituidas. composiciones farmaceuticas. |
| US20090075980A1 (en) * | 2003-10-03 | 2009-03-19 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and Analogs Thereof |
| KR20060120069A (ko) | 2003-10-03 | 2006-11-24 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 피라졸로피리딘 및 그의 유사체 |
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| CA2545825A1 (en) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Hydroxylamine substituted imidazo ring compounds |
| EP1686992A4 (de) * | 2003-11-25 | 2009-11-04 | 3M Innovative Properties Co | Hydroxylamin- und oxim-substituierte imidazochinoline, imidazopyridine und imidazonaphthyridine |
| CA2547020C (en) * | 2003-11-25 | 2014-03-25 | 3M Innovative Properties Company | 1h-imidazo[4,5-c]pyridine-4-amine derivatives as immune response modifier |
| JP2007513170A (ja) * | 2003-12-04 | 2007-05-24 | スリーエム イノベイティブ プロパティズ カンパニー | スルホン置換イミダゾ環エーテル |
| JP2007517035A (ja) * | 2003-12-29 | 2007-06-28 | スリーエム イノベイティブ プロパティズ カンパニー | アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン |
| JP2007530450A (ja) * | 2003-12-29 | 2007-11-01 | スリーエム イノベイティブ プロパティズ カンパニー | ピペラジン、[1,4]ジアゼパン、[1,4]ジアゾカン、および[1,5]ジアゾカン縮合イミダゾ環化合物 |
| EP1699788A2 (de) * | 2003-12-30 | 2006-09-13 | 3M Innovative Properties Company | Imidazochinolinyl-, imidazopyridinyl- und imidazonaphthyridinylsulfonamide |
| WO2005094531A2 (en) * | 2004-03-24 | 2005-10-13 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
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| EP1804583A4 (de) * | 2004-10-08 | 2009-05-20 | 3M Innovative Properties Co | Adjuvans für dna-impfstoffe |
| EP1819364A4 (de) * | 2004-12-08 | 2010-12-29 | 3M Innovative Properties Co | Immunmodulatorische zusammensetzungen, kombinationen und verfahren |
| JP5543068B2 (ja) * | 2004-12-30 | 2014-07-09 | スリーエム イノベイティブ プロパティズ カンパニー | キラル縮合[1,2]イミダゾ[4,5−c]環状化合物 |
| EP1831221B1 (de) | 2004-12-30 | 2012-08-08 | 3M Innovative Properties Company | Substituierte, chirale, fusionierte 1,2 imidazo-4,5-c-ringverbindungen |
| US8436176B2 (en) * | 2004-12-30 | 2013-05-07 | Medicis Pharmaceutical Corporation | Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine |
| CA2592897A1 (en) * | 2004-12-30 | 2006-07-13 | Takeda Pharmaceutical Company Limited | 1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine ethanesulfonate and 1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine methanesulfonate |
| PL1830876T3 (pl) * | 2004-12-30 | 2015-09-30 | Meda Ab | Zastosowanie imikwimodu do leczenia przerzutów do skóry wywodzących się od guza stanowiącego raka piersi |
| AU2006210392A1 (en) * | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Aqueous gel formulations containing immune response modifiers |
| AU2006212765B2 (en) * | 2005-02-09 | 2012-02-02 | 3M Innovative Properties Company | Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines |
| US8378102B2 (en) | 2005-02-09 | 2013-02-19 | 3M Innovative Properties Company | Oxime and hydroxylamine substituted thiazolo[4,5-c] ring compounds and methods |
| AU2006213746A1 (en) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods |
| EP1845988A2 (de) * | 2005-02-11 | 2007-10-24 | 3M Innovative Properties Company | Substituierte imidazochinoline und imidazonaphthyridine |
| EP1851220A2 (de) | 2005-02-23 | 2007-11-07 | 3M Innovative Properties Company | Hydroxyalkylsubstituierte imidazonaphthyridine |
| AU2006216686A1 (en) * | 2005-02-23 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Method of preferentially inducing the biosynthesis of interferon |
| JP2008531567A (ja) * | 2005-02-23 | 2008-08-14 | コーリー ファーマシューティカル グループ,インコーポレイテッド | ヒドロキシアルキル置換イミダゾキノリン化合物および方法 |
| EP1851224A2 (de) * | 2005-02-23 | 2007-11-07 | 3M Innovative Properties Company | Hydroxyalkyl-substituierte imidazochinoline |
| AU2006232375A1 (en) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases |
| EP1869043A2 (de) | 2005-04-01 | 2007-12-26 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridin-1,4-diamine und analoge davon |
| CA2605808A1 (en) * | 2005-04-25 | 2006-11-02 | 3M Innovative Properties Company | Immunostimulatory compositions |
| EA200800782A1 (ru) * | 2005-09-09 | 2008-08-29 | Коли Фармасьютикал Груп, Инк. | ПРОИЗВОДНЫЕ АМИДА И КАРБАМАТА N-{2-[4-АМИНО-2-(ЭТОКСИМЕТИЛ)-1Н-ИМИДАЗОЛО[4,5-c]ХИНОЛИН-1-IL]-1,1-ДИМЕТИЛЭТИЛ}МЕТАНСУЛЬФОНАМИДА И СПОСОБЫ |
| ZA200803029B (en) * | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
| KR20080083270A (ko) | 2005-11-04 | 2008-09-17 | 콜레이 파마시티컬 그룹, 인코포레이티드 | 하이드록시 및 알콕시 치환된 1에이치 이미다조퀴놀린 및방법 |
| EP1988896A4 (de) | 2006-02-22 | 2011-07-27 | 3M Innovative Properties Co | Konjugate zur modifizierung von immunreaktionen |
| US8329721B2 (en) * | 2006-03-15 | 2012-12-11 | 3M Innovative Properties Company | Hydroxy and alkoxy substituted 1H-imidazonaphthyridines and methods |
| US7906506B2 (en) * | 2006-07-12 | 2011-03-15 | 3M Innovative Properties Company | Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods |
| US8178539B2 (en) * | 2006-09-06 | 2012-05-15 | 3M Innovative Properties Company | Substituted 3,4,6,7-tetrahydro-5H-1,2a,4a,8-tetraazacyclopenta[cd]phenalenes and methods |
| US20080149123A1 (en) | 2006-12-22 | 2008-06-26 | Mckay William D | Particulate material dispensing hairbrush with combination bristles |
| US9242980B2 (en) | 2010-08-17 | 2016-01-26 | 3M Innovative Properties Company | Lipidated immune response modifier compound compositions, formulations, and methods |
| JP6460789B2 (ja) | 2011-06-03 | 2019-01-30 | スリーエム イノベイティブ プロパティズ カンパニー | ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体 |
| BR112013031039B1 (pt) | 2011-06-03 | 2020-04-28 | 3M Innovative Properties Co | compostos de hidrazino 1h-imidazoquinolina-4-aminas, conjugados feitos destes compostos, composição e composição farmacêutica compreendendo ditos compostos e conjugados, usos dos mesmos e método de fabricação do conjugado |
| CN104725304B (zh) * | 2013-12-18 | 2017-08-18 | 上海医药工业研究院 | 一种3‑取代‑2‑氰基吡啶类化合物的制备方法 |
| WO2019123178A1 (en) | 2017-12-20 | 2019-06-27 | 3M Innovative Properties Company | Amide substitued imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier |
| FR3113287B1 (fr) | 2020-08-07 | 2023-06-23 | Phv Pharma | Procédé industriel de synthèse de l’imiquimod à partir de la quinolèine-2,4-diol applicable à son utilisation pharmaceutique |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1271477A (en) | 1983-11-18 | 1990-07-10 | John F. Gerster | 1h-imidazo[4,5-c]quinolin-4-amines |
| IL73534A (en) | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| ZA848968B (en) | 1983-11-18 | 1986-06-25 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines |
| US4689388A (en) | 1985-01-24 | 1987-08-25 | Ajinomoto Co., Inc. | One pack type alicyclic epoxy resin compositions |
| US5238944A (en) | 1988-12-15 | 1993-08-24 | Riker Laboratories, Inc. | Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine |
| US5756747A (en) | 1989-02-27 | 1998-05-26 | Riker Laboratories, Inc. | 1H-imidazo 4,5-c!quinolin-4-amines |
| EP0385630B1 (de) | 1989-02-27 | 1996-11-27 | Riker Laboratories, Inc. | 4-Amino-1H-Imidazo(4,5-c)chinoline als antivirale Mittel |
| US4988815A (en) | 1989-10-26 | 1991-01-29 | Riker Laboratories, Inc. | 3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines |
| DK0553202T3 (da) * | 1990-10-05 | 1995-07-03 | Minnesota Mining & Mfg | Fremgangsmåde til fremstilling af imidazo(4,5-c)quinolin-4-aminer |
| JP2941413B2 (ja) | 1990-11-28 | 1999-08-25 | ライカー ラボラトリース インコーポレーテッド | 1H―イミダゾ[4,5―c]キノリン類の製造方法 |
| US5175296A (en) | 1991-03-01 | 1992-12-29 | Minnesota Mining And Manufacturing Company | Imidazo[4,5-c]quinolin-4-amines and processes for their preparation |
| US5395937A (en) | 1993-01-29 | 1995-03-07 | Minnesota Mining And Manufacturing Company | Process for preparing quinoline amines |
| JP3257893B2 (ja) * | 1993-10-18 | 2002-02-18 | 三菱電機株式会社 | 位相シフトマスク、その位相シフトマスクの製造方法およびその位相シフトマスクを用いた露光方法 |
| US5741908A (en) | 1996-06-21 | 1998-04-21 | Minnesota Mining And Manufacturing Company | Process for reparing imidazoquinolinamines |
| CA2399136A1 (en) | 2000-02-09 | 2001-08-16 | Hideo Kato | 1h-imidazopyridine derivatives |
| GB0211649D0 (en) * | 2002-05-21 | 2002-07-03 | Novartis Ag | Organic compounds |
| PT1539752E (pt) * | 2002-07-26 | 2007-05-31 | Teva Gyogyszergyar Zartkoeruen | Preparação de 1h-imidazo [4,5-c] quinolina-4-aminas via novos intermediários imidazo [4,5-c] quinolina-4-ciano e 1h-imidazo [4,5-c] quinolina-4-carboxamida |
-
2003
- 2003-07-28 PT PT03771977T patent/PT1539752E/pt unknown
- 2003-07-28 DK DK03771977T patent/DK1539752T3/da active
- 2003-07-28 CN CNB038225409A patent/CN100372847C/zh not_active Expired - Fee Related
- 2003-07-28 DE DE60312701T patent/DE60312701T8/de not_active Expired - Fee Related
- 2003-07-28 MX MXPA05000997A patent/MXPA05000997A/es unknown
- 2003-07-28 KR KR1020057001402A patent/KR20050030958A/ko not_active Ceased
- 2003-07-28 HR HR20050183A patent/HRP20050183A2/xx not_active Application Discontinuation
- 2003-07-28 ES ES03771977T patent/ES2282691T3/es not_active Expired - Lifetime
- 2003-07-28 PL PL03374866A patent/PL374866A1/xx unknown
- 2003-07-28 EP EP03771977A patent/EP1539752B1/de not_active Expired - Lifetime
- 2003-07-28 US US10/628,927 patent/US6841678B2/en not_active Expired - Fee Related
- 2003-07-28 SI SI200330819T patent/SI1539752T1/sl unknown
- 2003-07-28 IL IL16630703A patent/IL166307A0/xx unknown
- 2003-07-28 CA CA002493158A patent/CA2493158A1/en not_active Abandoned
- 2003-07-28 WO PCT/US2003/023543 patent/WO2004011462A1/en not_active Ceased
- 2003-07-28 JP JP2004524952A patent/JP2005537287A/ja active Pending
- 2003-07-28 AT AT03771977T patent/ATE357445T1/de not_active IP Right Cessation
- 2003-07-28 AU AU2003254221A patent/AU2003254221A1/en not_active Abandoned
-
2004
- 2004-12-09 US US11/009,259 patent/US7166721B2/en not_active Expired - Fee Related
- 2004-12-09 US US11/008,846 patent/US7335772B2/en not_active Expired - Fee Related
-
2005
- 2005-01-16 IL IL166307A patent/IL166307A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050030958A (ko) | 2005-03-31 |
| PL374866A1 (en) | 2005-11-14 |
| HRP20050183A2 (en) | 2005-06-30 |
| DE60312701D1 (de) | 2007-05-03 |
| WO2004011462A1 (en) | 2004-02-05 |
| US20050101627A1 (en) | 2005-05-12 |
| DE60312701T8 (de) | 2008-08-21 |
| AU2003254221A1 (en) | 2004-02-16 |
| MXPA05000997A (es) | 2005-05-16 |
| ES2282691T3 (es) | 2007-10-16 |
| DE60312701T2 (de) | 2007-12-06 |
| US6841678B2 (en) | 2005-01-11 |
| CN1684963A (zh) | 2005-10-19 |
| PT1539752E (pt) | 2007-05-31 |
| US7166721B2 (en) | 2007-01-23 |
| US20050119294A1 (en) | 2005-06-02 |
| SI1539752T1 (sl) | 2007-08-31 |
| EP1539752B1 (de) | 2007-03-21 |
| JP2005537287A (ja) | 2005-12-08 |
| CN100372847C (zh) | 2008-03-05 |
| DK1539752T3 (da) | 2007-07-16 |
| US20040063743A1 (en) | 2004-04-01 |
| ATE357445T1 (de) | 2007-04-15 |
| US7335772B2 (en) | 2008-02-26 |
| IL166307A (en) | 2010-04-15 |
| EP1539752A1 (de) | 2005-06-15 |
| CA2493158A1 (en) | 2004-02-05 |
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