IL165877A0 - Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores - Google Patents
Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophoresInfo
- Publication number
- IL165877A0 IL165877A0 IL16587704A IL16587704A IL165877A0 IL 165877 A0 IL165877 A0 IL 165877A0 IL 16587704 A IL16587704 A IL 16587704A IL 16587704 A IL16587704 A IL 16587704A IL 165877 A0 IL165877 A0 IL 165877A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- compositions
- polynucleotides
- target polynucleotide
- analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
- B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/107—Modifications characterised by incorporating a peptide nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/125—Specific component of sample, medium or buffer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/107—Alteration in the property of hybridised versus free label oligonucleotides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39052402P | 2002-06-20 | 2002-06-20 | |
US40626602P | 2002-08-26 | 2002-08-26 | |
PCT/US2003/019678 WO2004001379A2 (en) | 2002-06-20 | 2003-06-20 | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
Publications (1)
Publication Number | Publication Date |
---|---|
IL165877A0 true IL165877A0 (en) | 2006-01-15 |
Family
ID=30003161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16587704A IL165877A0 (en) | 2002-06-20 | 2004-12-20 | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
Country Status (12)
Country | Link |
---|---|
US (2) | US7214489B2 (de) |
EP (2) | EP1534857B1 (de) |
JP (1) | JP4528115B2 (de) |
KR (1) | KR20050010956A (de) |
CN (2) | CN1675377B (de) |
AT (1) | ATE476521T1 (de) |
AU (1) | AU2003243722A1 (de) |
CA (1) | CA2489922C (de) |
DE (1) | DE60333646D1 (de) |
EA (1) | EA007652B1 (de) |
IL (1) | IL165877A0 (de) |
WO (1) | WO2004001379A2 (de) |
Families Citing this family (57)
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GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
EP1468116A2 (de) | 2002-01-16 | 2004-10-20 | Dynal Biotech ASA | Verfahren zur isolierung von nukleinsäuren und proteinen aus einer einzigen probe |
US10001475B2 (en) | 2002-06-20 | 2018-06-19 | The Regents Of The University Of California | Light harvesting multichromophore compositions and methods of using the same |
US9371559B2 (en) | 2002-06-20 | 2016-06-21 | The Regents Of The University Of California | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
US7144950B2 (en) | 2003-09-17 | 2006-12-05 | The Regents Of The University Of California | Conformationally flexible cationic conjugated polymers |
CA2489922C (en) | 2002-06-20 | 2016-08-16 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
US7270956B2 (en) | 2002-08-26 | 2007-09-18 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
GB0229287D0 (en) * | 2002-12-16 | 2003-01-22 | Dna Res Innovations Ltd | Polyfunctional reagents |
WO2004077014A2 (en) * | 2003-02-13 | 2004-09-10 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotide-binding protein interactions using light harvesting multichromophores |
WO2005056628A2 (en) | 2003-09-17 | 2005-06-23 | The Regents Of The University Of California | Methods and devices comprising soluble conjugated polymers |
US8309672B2 (en) | 2004-09-03 | 2012-11-13 | The Regents Of The University Of California | Soluble conjugated polymers |
WO2006029226A1 (en) | 2004-09-03 | 2006-03-16 | The Regents Of The University Of California | Methods and devices utilizing soluble conjugated polymers |
EP1838752B1 (de) * | 2005-01-10 | 2017-10-04 | The Regents of The University of California | Kationische konjugierte polymere zur strangspezifischen polynukleotid-erkennung in homogenen festkörper-testanordnungen |
US7811755B2 (en) | 2005-01-10 | 2010-10-12 | The Regents Of The University Of California | Methods and articles for strand-specific polynucleotide detection with cationic multichromophores |
WO2006083932A2 (en) | 2005-01-31 | 2006-08-10 | The Regents Of The University | Methods and compositions for aggregant detection |
DE112006000495B4 (de) | 2005-03-01 | 2017-11-09 | The Regents Of The University Of California | Mehrschichtige Licht emittierende Polymer-Diode für Festkörper Beleuchtungs-Anwendungen |
WO2006092063A1 (en) * | 2005-03-03 | 2006-09-08 | National Research Council Canada | Methods and compositions for the detection and analysis of nucleic acids by signal amplification |
US8309304B2 (en) | 2006-02-10 | 2012-11-13 | The University Of Hong Kong | Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes |
US8057989B2 (en) * | 2006-02-10 | 2011-11-15 | The University Of Hong Kong | Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes |
US8158444B2 (en) | 2006-10-06 | 2012-04-17 | Sirigen, Inc. | Fluorescent methods and materials for directed biomarker signal amplification |
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KR20080060744A (ko) * | 2006-12-27 | 2008-07-02 | 한국조폐공사 | 피엔에이 함유 잉크 및 이의 확인방법 |
WO2009009889A1 (en) * | 2007-07-13 | 2009-01-22 | National Research Council Of Canada | Ultrasensitive detection of target using target-ready particles |
US20090137925A1 (en) * | 2007-11-23 | 2009-05-28 | Divya Cantor | Impedance Spectroscopy Cervix Scanning Apparatus and Method |
US20090230362A1 (en) * | 2008-01-25 | 2009-09-17 | Bazan Guillermo C | Conjugated oligoelectrolyte electron transporting layers |
US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
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US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
US8969509B2 (en) | 2009-06-26 | 2015-03-03 | Sirigen, Inc. | Signal amplified biological detection with conjugated polymers |
EP4322238A3 (de) | 2010-01-19 | 2024-05-15 | Sirigen II Limited | Neuartige reagenzien für ausgerichtete biomarkersignalverstärkung |
WO2015050869A1 (en) | 2013-10-02 | 2015-04-09 | Becton Dickinson And Company | Polymersome encapsulation of hydrophobic fluorescent polymers |
JP2018505414A (ja) * | 2015-02-02 | 2018-02-22 | ツー ポア ガイズ インコーポレイテッド | サンプルバックグラウンドからの標的ポリヌクレオチドのナノ細孔検出方法 |
CN107428918B (zh) | 2015-03-12 | 2021-07-30 | 贝克顿·迪金森公司 | 紫外线吸收聚合物染料及其使用方法 |
US10408759B2 (en) | 2015-05-26 | 2019-09-10 | Becton, Dickinson And Company | Methods and systems for high resolution fluorescence microscopy of polymeric dye-labeled samples using polarized light |
US10472521B2 (en) | 2015-12-16 | 2019-11-12 | Becton, Dickinson And Company | Photostable fluorescent polymeric tandem dyes including luminescent metal complexes |
CN108473505B (zh) | 2016-03-28 | 2019-11-05 | 阿特生物探索公司 | 聚芴并[4,5-cde]氧杂环庚三烯偶联物及其在分析物检测方法中的用途 |
US11208527B2 (en) | 2016-04-15 | 2021-12-28 | Beckman Coulter, Inc. | Photoactive macromolecules and uses thereof |
EP3446118B1 (de) | 2016-04-22 | 2024-01-24 | Becton, Dickinson and Company | Multiplex-polymerfarbvorrichtungen und verfahren zur verwendung davon |
CN109562379A (zh) | 2016-06-20 | 2019-04-02 | 拜克门寇尔特公司 | 用于染料共轭试剂的干燥过程 |
CN109661439A (zh) | 2016-07-07 | 2019-04-19 | 贝克顿·迪金森公司 | 发荧光的水溶剂化共轭聚合物 |
WO2018009861A1 (en) | 2016-07-08 | 2018-01-11 | Biolegend | Substituted polyfluorene compounds |
EP3481900A4 (de) | 2016-07-11 | 2020-03-18 | Becton, Dickinson and Company | Mittels blaulicht erregbare wassersolvatisierte polymerfarbstoffe |
CN106770088B (zh) * | 2016-11-24 | 2019-06-11 | 北京科技大学 | 用于dna检测的荧光复合纳米粒子的制备及检测方法 |
AU2017375751B2 (en) | 2016-12-12 | 2021-05-20 | Becton, Dickinson And Company | Water-soluble polymeric dyes |
JP7058662B2 (ja) | 2017-02-08 | 2022-04-22 | ベクトン・ディキンソン・アンド・カンパニー | 乾燥色素試薬装置、ならびにその製造及び使用方法 |
CN106857504B (zh) * | 2017-02-10 | 2020-03-10 | 中国科学院化学研究所 | 一种抑制和/或破坏生物膜的方法 |
KR20230147735A (ko) | 2017-06-16 | 2023-10-23 | 듀크 유니버시티 | 개선된 라벨 검출, 계산, 분석물 감지, 및 조정 가능한 난수 생성을 위한 공진기 네트워크 |
WO2019023463A1 (en) | 2017-07-28 | 2019-01-31 | Biolegend | CONJUGATED POLYMERS AND METHODS OF USE |
US11492493B2 (en) | 2017-12-26 | 2022-11-08 | Becton, Dickinson And Company | Deep ultraviolet-excitable water-solvated polymeric dyes |
CN117180836A (zh) | 2018-11-13 | 2023-12-08 | 贝克顿·迪金森公司 | 干燥试剂滤网及其制造和使用方法 |
CN111850103B (zh) * | 2020-08-20 | 2022-12-02 | 清华大学深圳国际研究生院 | 一种基于阳离子共轭聚合物和核酸酶辅助循环扩增的检测目的核酸的方法 |
JP2023550721A (ja) | 2020-11-13 | 2023-12-05 | ベックマン コールター, インコーポレイテッド | 蛍光性ポリマーコンジュゲートと生物学的試料中の細胞との間の非特異的相互作用を低下させるための添加剤 |
AU2022216619A1 (en) | 2021-02-05 | 2023-09-07 | Beckman Coulter, Inc. | Compositions and methods for preventing non-specific interactions between polymer dyes-antibody conjugates |
EP4334395A1 (de) | 2021-05-04 | 2024-03-13 | Beckman Coulter, Inc. | Uv-absorbierende polymere, zusammensetzungen und verwendungen davon |
WO2023086103A1 (en) | 2021-11-12 | 2023-05-19 | Beckman Coulter, Inc. | Novel formulation for drying of polymer dye conjugated antibodies |
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CA2489922C (en) | 2002-06-20 | 2016-08-16 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
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-
2003
- 2003-06-20 CA CA2489922A patent/CA2489922C/en not_active Expired - Lifetime
- 2003-06-20 CN CN038198363A patent/CN1675377B/zh not_active Expired - Lifetime
- 2003-06-20 KR KR10-2004-7020729A patent/KR20050010956A/ko not_active Application Discontinuation
- 2003-06-20 WO PCT/US2003/019678 patent/WO2004001379A2/en active Application Filing
- 2003-06-20 US US10/600,286 patent/US7214489B2/en active Active
- 2003-06-20 EP EP03761235A patent/EP1534857B1/de not_active Expired - Lifetime
- 2003-06-20 CN CN2012102827293A patent/CN102766695A/zh active Pending
- 2003-06-20 JP JP2004516105A patent/JP4528115B2/ja not_active Expired - Lifetime
- 2003-06-20 AU AU2003243722A patent/AU2003243722A1/en not_active Abandoned
- 2003-06-20 AT AT03761235T patent/ATE476521T1/de not_active IP Right Cessation
- 2003-06-20 EA EA200500041A patent/EA007652B1/ru unknown
- 2003-06-20 DE DE60333646T patent/DE60333646D1/de not_active Expired - Lifetime
- 2003-06-20 EP EP10008095A patent/EP2278027A3/de not_active Ceased
-
2004
- 2004-12-20 IL IL16587704A patent/IL165877A0/xx unknown
-
2007
- 2007-05-08 US US11/746,055 patent/US8101416B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2278027A2 (de) | 2011-01-26 |
WO2004001379A3 (en) | 2004-06-03 |
CN102766695A (zh) | 2012-11-07 |
AU2003243722A1 (en) | 2004-01-06 |
EP1534857A4 (de) | 2007-10-31 |
WO2004001379A2 (en) | 2003-12-31 |
CA2489922C (en) | 2016-08-16 |
EA200500041A1 (ru) | 2005-08-25 |
US8101416B2 (en) | 2012-01-24 |
JP2005530182A (ja) | 2005-10-06 |
CN1675377B (zh) | 2012-10-03 |
CN1675377A (zh) | 2005-09-28 |
EP1534857A2 (de) | 2005-06-01 |
EP1534857B1 (de) | 2010-08-04 |
KR20050010956A (ko) | 2005-01-28 |
US20040219556A1 (en) | 2004-11-04 |
US7214489B2 (en) | 2007-05-08 |
US20080280369A1 (en) | 2008-11-13 |
EP2278027A3 (de) | 2011-02-16 |
CA2489922A1 (en) | 2003-12-31 |
ATE476521T1 (de) | 2010-08-15 |
EA007652B1 (ru) | 2006-12-29 |
JP4528115B2 (ja) | 2010-08-18 |
DE60333646D1 (de) | 2010-09-16 |
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