AU2001250937A1 - Loop probe hybridization assay for polynucleotide analysis - Google Patents

Loop probe hybridization assay for polynucleotide analysis

Info

Publication number
AU2001250937A1
AU2001250937A1 AU2001250937A AU5093701A AU2001250937A1 AU 2001250937 A1 AU2001250937 A1 AU 2001250937A1 AU 2001250937 A AU2001250937 A AU 2001250937A AU 5093701 A AU5093701 A AU 5093701A AU 2001250937 A1 AU2001250937 A1 AU 2001250937A1
Authority
AU
Australia
Prior art keywords
hybridization assay
probe hybridization
loop probe
polynucleotide analysis
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001250937A
Inventor
Marcel P. Bruchez
Jennifer H. Lai
Vince E. Phillips
Andrew R. Watson
Edith Y. Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Quantum Dot Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantum Dot Corp filed Critical Quantum Dot Corp
Publication of AU2001250937A1 publication Critical patent/AU2001250937A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
AU2001250937A 2000-03-22 2001-03-22 Loop probe hybridization assay for polynucleotide analysis Abandoned AU2001250937A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19122700P 2000-03-22 2000-03-22
US60191227 2000-03-22
US23700000P 2000-09-29 2000-09-29
US60237000 2000-09-29
PCT/US2001/009242 WO2001071043A1 (en) 2000-03-22 2001-03-22 Loop probe hybridization assay for polynucleotide analysis

Publications (1)

Publication Number Publication Date
AU2001250937A1 true AU2001250937A1 (en) 2001-10-03

Family

ID=26886876

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001249386A Abandoned AU2001249386A1 (en) 2000-03-22 2001-03-22 Methods of using semiconductor nanocrystals in bead-based nucleic acid assays
AU2001250937A Abandoned AU2001250937A1 (en) 2000-03-22 2001-03-22 Loop probe hybridization assay for polynucleotide analysis

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU2001249386A Abandoned AU2001249386A1 (en) 2000-03-22 2001-03-22 Methods of using semiconductor nanocrystals in bead-based nucleic acid assays

Country Status (6)

Country Link
US (4) US6500622B2 (en)
EP (2) EP1276904B1 (en)
JP (1) JP2004500109A (en)
AU (2) AU2001249386A1 (en)
CA (1) CA2403708A1 (en)
WO (2) WO2001071043A1 (en)

Families Citing this family (275)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846717A (en) * 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
WO1994003624A1 (en) * 1992-08-04 1994-02-17 Auerbach Jeffrey I Methods for the isothermal amplification of nucleic acid molecules
US6261808B1 (en) * 1992-08-04 2001-07-17 Replicon, Inc. Amplification of nucleic acid molecules via circular replicons
US7432048B2 (en) * 1996-11-29 2008-10-07 Third Wave Technologies, Inc. Reactions on a solid surface
US6607829B1 (en) 1997-11-13 2003-08-19 Massachusetts Institute Of Technology Tellurium-containing nanocrystalline materials
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
ATE440963T1 (en) * 1998-07-02 2009-09-15 Gen Probe Inc MOLECULAR TORCHES
US7079241B2 (en) * 2000-04-06 2006-07-18 Invitrogen Corp. Spatial positioning of spectrally labeled beads
US7192778B2 (en) * 1999-10-06 2007-03-20 Natan Michael J Surface enhanced spectroscopy-active composite nanoparticles
US8497131B2 (en) * 1999-10-06 2013-07-30 Becton, Dickinson And Company Surface enhanced spectroscopy-active composite nanoparticles comprising Raman-active reporter molecules
WO2001071043A1 (en) * 2000-03-22 2001-09-27 Quantum Dot Corporation Loop probe hybridization assay for polynucleotide analysis
US20020090650A1 (en) * 2000-04-06 2002-07-11 Quantum Dot Corporation Two-dimensional spectral imaging system
EP1313881A2 (en) 2000-06-06 2003-05-28 TM Bioscience Corporation Capture moieties for nucleic acids and uses thereof
US7892854B2 (en) * 2000-06-21 2011-02-22 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US6934408B2 (en) * 2000-08-25 2005-08-23 Amnis Corporation Method and apparatus for reading reporter labeled beads
WO2002018951A2 (en) * 2000-08-29 2002-03-07 The Rockefeller University Methods employing fluorescence quenching by metal surfaces
JP2004515229A (en) * 2000-11-27 2004-05-27 スローン−ケッタリング インスティテュート フォー キャンサー リサーチ Methods of using fluorescent energy conversion probes to detect nucleic acid cleavage
US20020086294A1 (en) * 2000-12-29 2002-07-04 Ellson Richard N. Device and method for tracking conditions in an assay
US6861263B2 (en) * 2001-01-26 2005-03-01 Surromed, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
US7115369B2 (en) * 2001-03-15 2006-10-03 Iowa State University Research Foundation, Inc. Functional nucleic acid probes and uses thereof
US6596489B2 (en) * 2001-03-30 2003-07-22 Applied Gene Technologies Methods and compositions for analyzing nucleotide sequence mismatches using RNase H
JP2002311027A (en) * 2001-04-09 2002-10-23 Hitachi Software Eng Co Ltd Beads, manufacturing method of beads, flow cytometer, and program
US20020164271A1 (en) * 2001-05-02 2002-11-07 Ho Winston Z. Wavelength-coded bead for bioassay and signature recogniton
US20030013109A1 (en) * 2001-06-21 2003-01-16 Ballinger Clinton T. Hairpin sensors using quenchable fluorescing agents
US7303869B2 (en) * 2001-07-17 2007-12-04 Northwestern University Solid-phase reactions
US7485443B2 (en) * 2001-07-17 2009-02-03 Northwestern University Solid-phase reactions
US7198897B2 (en) * 2001-12-19 2007-04-03 Brandeis University Late-PCR
IL147554A (en) * 2002-01-10 2005-11-20 Kiloambda Ip Ltd Optical limiter
WO2003089906A2 (en) * 2002-04-22 2003-10-30 University Of Florida Functionalized nanoparticles and methods of use
US20030215864A1 (en) * 2002-04-23 2003-11-20 U.S. Genomics, Inc. Compositions and methods related to two-arm nucleic acid probes
AU2003299478A1 (en) 2002-05-07 2004-05-25 Regents Of The University Of California Bioactivation of particles
DE10221792A1 (en) * 2002-05-15 2003-11-27 Caesar Stiftung Elasto-optical biosensor
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
US7144950B2 (en) * 2003-09-17 2006-12-05 The Regents Of The University Of California Conformationally flexible cationic conjugated polymers
AU2003243722A1 (en) 2002-06-20 2004-01-06 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
US9371559B2 (en) 2002-06-20 2016-06-21 The Regents Of The University Of California Compositions for detection and analysis of polynucleotides using light harvesting multichromophores
KR100460881B1 (en) * 2002-06-28 2004-12-09 현대자동차주식회사 System and method for controlling power conversion of fuel cell hybrid electric vehicle
WO2004007692A2 (en) * 2002-07-17 2004-01-22 U.S.Genomics, Inc. Methods and compositions for analyzing polymers using chimeric tags
US7508608B2 (en) * 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US20050227252A1 (en) * 2002-08-20 2005-10-13 Moon John A Diffraction grating-based encoded articles for multiplexed experiments
US7399643B2 (en) * 2002-09-12 2008-07-15 Cyvera Corporation Method and apparatus for aligning microbeads in order to interrogate the same
US7872804B2 (en) * 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7441703B2 (en) * 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7900836B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
WO2004092324A2 (en) 2002-08-26 2004-10-28 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
PL375252A1 (en) * 2002-09-06 2005-11-28 Chiron Corporation Methods for verifying fluid movement
CA2499037A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Method and apparatus for labelling using diffraction grating-based encoded optical identification elements
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
US7092160B2 (en) * 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
CA2498913A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Assay stick comprising coded microbeads
AU2003270726A1 (en) * 2002-09-12 2004-04-30 Cidra Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
US20040101822A1 (en) * 2002-11-26 2004-05-27 Ulrich Wiesner Fluorescent silica-based nanoparticles
US20070059693A1 (en) * 2003-01-02 2007-03-15 University Of Rochester Hybridization-based biosensor containing hairpin probes and use thereof
JP4073323B2 (en) * 2003-01-23 2008-04-09 日立ソフトウエアエンジニアリング株式会社 Functional beads, reading method and reading apparatus thereof
US20040152085A1 (en) * 2003-02-04 2004-08-05 Veridian Systems Division Surface for collection and/or purification of nucleic acids
US7223851B2 (en) * 2003-02-06 2007-05-29 General Dynamics Advanced Information Systems, Inc. Nucleic acid-binding polymers
JP4740111B2 (en) 2003-02-13 2011-08-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Methods and compositions for detecting and analyzing polynucleotide binding protein interactions using light collecting multichromophores
AU2004219707B2 (en) * 2003-03-07 2009-04-23 Rutgers, The State University Of New Jersey Optically decodable microcarriers, arrays and methods
JP4180964B2 (en) * 2003-04-18 2008-11-12 日立ソフトウエアエンジニアリング株式会社 Bead array structure, manufacturing method thereof, and bead array method of capillary bead array
US20040214176A1 (en) * 2003-04-22 2004-10-28 Osborne James C. Multiplexed DNA assays using structure-specific endonucleases
US7385043B1 (en) * 2003-04-30 2008-06-10 The Public Health Research Institute Of The City Of New York, Inc. Homogeneous multiplex screening assays and kits
WO2005016824A2 (en) * 2003-05-05 2005-02-24 The Research Foundation Of State University Of Newyork Synthesis of nanoparticles by an emulsion-gas contacting process
GB0311948D0 (en) * 2003-05-23 2003-06-25 Stockport Innovation Ltd Light emitting probes
EP1639304A1 (en) * 2003-06-18 2006-03-29 Bratya Vassilevi Ad Refrigerator and system of refrigerators
JP2007531496A (en) * 2003-07-11 2007-11-08 サロメッド,インコーポレイテッド Multiplex molecular beacon assay for detecting pathogens
US8796030B2 (en) 2003-07-12 2014-08-05 Parallel Synthesis Technologies, Inc. Methods for optically encoding an object with upconverting materials and compositions used therein
WO2005010211A1 (en) * 2003-07-28 2005-02-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Optical detection of analytes by use of semiconductor nanoparticles
CA2534402C (en) * 2003-08-04 2013-06-25 Emory University Porous materials embedded with nanospecies, methods of fabrication thereof, and methods of use thereof
WO2005022162A1 (en) * 2003-08-21 2005-03-10 U.S. Genomics, Inc. Quantum dots and methods of use thereof
US7198900B2 (en) * 2003-08-29 2007-04-03 Applera Corporation Multiplex detection compositions, methods, and kits
US20050069895A1 (en) * 2003-08-29 2005-03-31 Applera Corporation Compositions, methods, and kits for fabricating coded molecular tags
US20050048498A1 (en) * 2003-08-29 2005-03-03 Applera Corporation Compositions, methods, and kits for assembling probes
US20060057729A1 (en) * 2003-09-12 2006-03-16 Illumina, Inc. Diffraction grating-based encoded element having a substance disposed thereon
DE112004001737B4 (en) 2003-09-17 2016-08-11 The Regents Of The University Of California A process comprising soluble, conjugated polymers for forming adjacent layers on a substrate or adding a polymer layer to a substrate, a multilayer electronic device and use in electronic components
US20050123959A1 (en) * 2003-09-30 2005-06-09 Brett Williams Methods and kits for hybridizing multiple probe panels to nucleic acid samples
AU2004282188B2 (en) 2003-10-15 2009-12-24 Board Of Regents, The University Of Texas System Multifunctional biomaterials as scaffolds for electronic, optical, magnetic, semiconducting, and biotechnological applications
WO2005046722A2 (en) * 2003-11-05 2005-05-26 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Carbohydrate antigen-nanoparticle conjugates and uses thereof as antimetastatic agents in treating cancer
US7413868B2 (en) * 2003-11-05 2008-08-19 Trellis Bioscience, Inc. Use of particulate labels in bioanalyte detection methods
WO2005053649A1 (en) * 2003-11-05 2005-06-16 The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services Biofunctionalized quantum dots for biological imaging
US7329391B2 (en) * 2003-12-08 2008-02-12 Applera Corporation Microfluidic device and material manipulating method using same
US20050147976A1 (en) * 2003-12-29 2005-07-07 Xing Su Methods for determining nucleotide sequence information
DE102004004882A1 (en) * 2004-01-30 2005-08-18 Dade Behring Marburg Gmbh Test system and method for detection of analytes
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US20080032420A1 (en) * 2004-03-30 2008-02-07 Lambert James L Surface Enhanced Raman Scattering and Multiplexed Diagnostic Assays
US20050250141A1 (en) * 2004-03-30 2005-11-10 Lambert James L Diagnostic assays including multiplexed lateral flow immunoassays with quantum dots
WO2006093516A2 (en) 2004-06-22 2006-09-08 The Regents Of The University Of California Peptide-coated nanoparticles with graded shell compositions
WO2006020363A2 (en) 2004-07-21 2006-02-23 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
JP2006055081A (en) * 2004-08-20 2006-03-02 Dnaform:Kk Method for typing gene polymorphism
DE112005002103T5 (en) * 2004-09-03 2007-07-26 The Regents Of The University Of California, Oakland Soluble conjugated polymers using methods and devices
US8309672B2 (en) * 2004-09-03 2012-11-13 The Regents Of The University Of California Soluble conjugated polymers
EP1812884A4 (en) * 2004-10-22 2009-09-02 Parallel Synthesis Technologie Rare earth downconverting phosphor compositions for optically encoding objects and methods and apparatus relating to same
US7682782B2 (en) * 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
US20060240590A1 (en) * 2004-11-09 2006-10-26 The Research Foundation Of State University Of New York Controlled synthesis of nanowires, nanodiscs, and nanostructured materials using liquid crystalline templates
EP2194485B1 (en) 2004-11-16 2012-10-17 Illumina, Inc. Method and apparatus for reading coded microbeads
US7604173B2 (en) * 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
WO2006055735A2 (en) * 2004-11-16 2006-05-26 Illumina, Inc Scanner having spatial light modulator
EP1836497B1 (en) 2004-12-16 2013-04-03 Life Technologies Corporation Quantum dot-encoded bead set for calibration and quantification of multiplexed assays, and methods for their use
US20060148103A1 (en) * 2004-12-30 2006-07-06 Yin-Peng Chen Highly sensitive biological assays
EP1838752B1 (en) * 2005-01-10 2017-10-04 The Regents of The University of California Cationic conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
WO2006074482A2 (en) * 2005-01-10 2006-07-13 The Regents Of The University Of California Methods and kits for strand-specific polynucleotide detection with cationic multichromophores
WO2006083932A2 (en) 2005-01-31 2006-08-10 The Regents Of The University Methods and compositions for aggregant detection
KR100704011B1 (en) * 2005-02-16 2007-04-04 한국과학기술원 Detection method for specific biomolecular interactions using FRET between metal nanoparticle and quantum dot
DE112006000495B4 (en) * 2005-03-01 2017-11-09 The Regents Of The University Of California Multilayer light emitting polymer diode for solid state lighting applications
WO2006096835A2 (en) * 2005-03-08 2006-09-14 Molecular Probes, Inc. Monitoring and manipulating cellular transmembrane potentials using nanostructures
WO2006105102A2 (en) * 2005-03-28 2006-10-05 The Research Foundation Of State University Of New York Synthesis of nanostructured materials using liquid crystalline templates
EP1869219A4 (en) * 2005-03-31 2010-06-23 Perkinelmer Las Inc Multiplex assay systems
US8084001B2 (en) * 2005-05-02 2011-12-27 Cornell Research Foundation, Inc. Photoluminescent silica-based sensors and methods of use
US20070228606A1 (en) * 2005-07-07 2007-10-04 Specialty Coating Systems, Inc. Nanoscale structures and methods of preparation
US7387813B2 (en) * 2005-07-07 2008-06-17 Specialty Coating Systems, Inc. Methods of preparation of hollow microstructures and nanostructures
US20070134815A1 (en) * 2005-07-11 2007-06-14 Danielle Chamberlin Sensitivity enhancement of POCT devices using gold and silver nanoparticles on substrates containing nanostructures or nanoparticles that interact with labeling particles
WO2007011660A2 (en) * 2005-07-14 2007-01-25 William Marsh Rice University Quantum dot probes
US20070128620A1 (en) * 2005-07-15 2007-06-07 Applera Corporation Hot start reverse transcription by primer design
WO2007014267A2 (en) * 2005-07-26 2007-02-01 Oregon Health & Science University Nanoparticle probes for capture, sorting and placement of targets
US7642086B2 (en) * 2005-08-09 2010-01-05 Canon Kabushiki Kaisha Labeled probe bound object, method for producing the same and method for using the same
JP2009523406A (en) * 2005-11-15 2009-06-25 オクソニカ・インコーポレーテッド SERS-based method for detection of bioagents
US7623624B2 (en) * 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
US8409863B2 (en) 2005-12-14 2013-04-02 Becton, Dickinson And Company Nanoparticulate chemical sensors using SERS
ES2374788T3 (en) 2005-12-23 2012-02-22 Nanostring Technologies, Inc. NANOINFORMERS AND METHODS FOR PRODUCTION AND USE.
CN101384732B (en) * 2005-12-23 2015-11-25 珀金埃尔默Las公司 The comparative genome hybridization of the multiplex particles of coding
US20070148390A1 (en) * 2005-12-27 2007-06-28 Specialty Coating Systems, Inc. Fluorinated coatings
US7723100B2 (en) 2006-01-13 2010-05-25 Becton, Dickinson And Company Polymer coated SERS nanotag
US7226752B1 (en) 2006-01-19 2007-06-05 Avago Technologies General Ip (Singapore) Pte. Ltd. Methods for detecting an analyte in a sample
WO2007090058A2 (en) * 2006-01-27 2007-08-09 Oxonica, Inc. Lateral flow immunoassay with encapsulated detection modality
WO2008057127A2 (en) * 2006-02-06 2008-05-15 Massachusetts Institute Of Technology Self-assembly of macromolecules on multilayered polymer surfaces
CA2571904A1 (en) * 2006-02-15 2007-08-15 Fio Corporation System and method of detecting pathogens
US20070228023A1 (en) * 2006-03-30 2007-10-04 Klaus Kleine Pulsed Synchronized Laser Cutting of Stents
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
WO2007125812A1 (en) * 2006-04-28 2007-11-08 Konica Minolta Medical & Graphic, Inc. Inorganic nanoparticle, process for producing the same, and biosubstance labeling agent having inorganic nanoparticle linked thereto
WO2008008349A2 (en) * 2006-07-11 2008-01-17 Drexel University Methods of quantitatively assessing inflammation with biosensing nanoparticles
US20080241071A1 (en) * 2006-07-14 2008-10-02 West Jennifer L Quantum Dot Probes
WO2008014223A2 (en) * 2006-07-24 2008-01-31 Becton, Dickinson And Company Assay particle concentration and imaging apparatus and method
US7764361B2 (en) * 2006-07-27 2010-07-27 Northwestern University Systems and methods to analyze multiplexed bead-based assays using backscattered light
WO2008039998A2 (en) * 2006-09-28 2008-04-03 President And Fellows Of Harvard College Methods for sequencing dna
CA2580589C (en) 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
WO2008085933A1 (en) * 2007-01-08 2008-07-17 Plextronics, Inc. Quantum dot photovoltaic device
WO2008103848A1 (en) * 2007-02-21 2008-08-28 Invitrogen Corporation Materials and methods for single molecule nucleic acid sequencing
WO2008109176A2 (en) 2007-03-07 2008-09-12 President And Fellows Of Harvard College Assays and other reactions involving droplets
US8360321B2 (en) 2007-04-02 2013-01-29 Fio Corporation System and method of deconvolving multiplexed fluorescence spectral signals generated by quantum dot optical coding technology
WO2009000084A1 (en) 2007-06-22 2008-12-31 Fio Corporation Systems and methods for manufacturing quantum dot-doped polymer microbeads
WO2009006739A1 (en) 2007-07-09 2009-01-15 Fio Corporation Systems and methods for enhancing fluorescent detection of target molecules in a test sample
US8790877B2 (en) * 2007-07-12 2014-07-29 The United States Of America As Represented By The Secretary Of The Air Force Using DNA aptamers and quantum dots for the detection of proteins or other targets
US20110212491A1 (en) * 2007-08-03 2011-09-01 Enigma Diagnostics Limited Reaction vessel
GB0715170D0 (en) * 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Reaction vessel
US8551763B2 (en) 2007-10-12 2013-10-08 Fio Corporation Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto
US8031924B2 (en) * 2007-11-30 2011-10-04 General Electric Company Methods and systems for removing autofluorescence from images
US9797010B2 (en) 2007-12-21 2017-10-24 President And Fellows Of Harvard College Systems and methods for nucleic acid sequencing
KR100970584B1 (en) 2008-02-28 2010-07-16 한국과학기술원 Nanoparticle-based biochip set for detecting glycoproteins
CN102119331A (en) 2008-06-05 2011-07-06 生命科技公司 Activation and monitoring of cellular transmembrane potentials
EP2307796A4 (en) * 2008-06-24 2012-08-08 Kilolambda Tech Ltd Light limiting window
WO2009155704A1 (en) 2008-06-25 2009-12-30 Fio Corporation Bio-threat alert system
EP2303771B1 (en) * 2008-06-30 2018-05-30 Life Technologies Corporation Methods for isolating and purifying nanoparticles from a complex medium
US8679543B2 (en) 2008-07-02 2014-03-25 Joseph Bartel Stable indium-containing semiconductor nanocrystals
WO2010022519A1 (en) 2008-08-29 2010-03-04 Fio Corporation A single-use handheld diagnostic test device, and an associated system and method for testing biological and environmental test samples
US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
DE102008062372B3 (en) * 2008-12-17 2010-06-17 Medizinische Hochschule Hannover Detecting conjugate and method of analysis
US8748094B2 (en) * 2008-12-19 2014-06-10 President And Fellows Of Harvard College Particle-assisted nucleic acid sequencing
EP2387721A4 (en) 2009-01-13 2014-05-14 Fio Corp A handheld diagnostic test device and method for use with an electronic device and a test cartridge in a rapid diagnostic test
US20110130297A1 (en) * 2009-01-23 2011-06-02 Bae Systems Information And Electronic Systems Integration Inc. Quantum dot-sensory array for biological recognition
GB2480792B (en) * 2009-03-02 2018-11-14 Co Diagnostics Inc Energy transfer hairpin oligonucleotide probes
WO2011011782A1 (en) * 2009-07-24 2011-01-27 Duke University Functionalized metal-coated energy converting nanoparticles, methods for production thereof and methods for use
DE10806564T1 (en) 2009-08-07 2013-05-08 Nec Soft, Ltd. NUCLEIC ACID ELEMENT FOR USE IN ANALYSIS AND ANALYSIS METHOD, ANALYSIS AGENT AND ANALYZING INSTRUMENT THEREWITH
CA2773798A1 (en) * 2009-09-09 2011-03-17 Absolute Software Corporation Alert for real-time risk of theft or loss
WO2011037802A2 (en) * 2009-09-28 2011-03-31 Igor Kutyavin Methods and compositions for detection of nucleic acids based on stabilized oligonucleotide probe complexes
US8378075B2 (en) 2009-10-27 2013-02-19 The United States Of America, As Represented By The Secretary Of The Navy Covalent attachment of peptides and biological molecules to luminescent semiconductor nanocrystals
TWI572389B (en) * 2009-11-10 2017-03-01 伊穆諾萊特公司 Instrument set and system for producing change in medium, system for generating light or curing, radiation-cured or curable article, microwave or rf receptor, and system for treatment or diagnosis
WO2011082293A1 (en) 2009-12-31 2011-07-07 Ventana Medical Systems, Inc. Methods for producing uniquely specific nucleic acid probes
CA2786853A1 (en) 2010-02-26 2011-09-01 Ventana Medical Systems, Inc. Cytogenic analysis of metaphase chromosomes
JP5726917B2 (en) 2010-02-26 2015-06-03 ヴェンタナ メディカル システムズ, インク. Poly tag probe
WO2012068511A2 (en) * 2010-11-19 2012-05-24 The Regents Of The University Of Califorina Method for amplification-free nucleic acid detection on optofluidic chips
CA2825453C (en) 2011-03-14 2016-05-10 Ventana Medical Systems, Inc. A method of analyzing chromosomal translocations and a system therefore
CN103649335B (en) 2011-05-04 2015-11-25 Htg分子诊断有限公司 Quantitative nucleic acid enzyme protection measures the improvement of (QNPA) and order-checking (QNPS)
WO2013057586A1 (en) 2011-10-19 2013-04-25 Oslo Universitetssykehus Hf Compositions and methods for producing soluble t - cell receptors
WO2013108126A2 (en) 2012-01-16 2013-07-25 University Of Oslo Methyltransferases and uses thereof
WO2013119793A1 (en) * 2012-02-07 2013-08-15 University Of Kansas Chemiluminescent nanoparticles and uses thereof
WO2013167387A1 (en) 2012-05-10 2013-11-14 Ventana Medical Systems, Inc. Uniquely specific probes for pten, pik3ca, met, top2a, and mdm2
DK2872646T3 (en) 2012-07-12 2017-12-04 Université Paris Descartes PROCEDURES FOR PREDICTING SURVIVAL TIME AND TREATMENT RESPONSE OF A PATIENT, SUFFERING A FAST CANCER WITH A SIGNATURE OF AT LEAST 7 GENES
WO2014048942A1 (en) 2012-09-25 2014-04-03 Ventana Medical Systems, Inc. Probes for pten, pik3ca, met, and top2a, and method for using the probes
KR102310098B1 (en) * 2013-02-19 2021-10-06 삼성전자주식회사 Conjugates of a metal nanoparticle and a light emitting material
WO2015036405A1 (en) 2013-09-10 2015-03-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosing and treating basal cell carcinoma
US20160265036A1 (en) 2013-11-05 2016-09-15 Htg Molecular Diagnostics, Inc. Methods for detecting nucleic acids
WO2015069634A1 (en) 2013-11-08 2015-05-14 President And Fellows Of Harvard College Microparticles, methods for their preparation and use
AU2015220784B2 (en) 2014-02-24 2021-02-04 Ventana Medical Systems, Inc. Automated RNA detection using labeled 2'-O-methyl RNA oligonucleotide probes and signal amplification systems
JP6289951B2 (en) * 2014-03-19 2018-03-07 株式会社東芝 Thin film biomolecule detection element, biomolecule detection method, and biomolecule detection apparatus
US10557855B2 (en) 2014-08-19 2020-02-11 Board Of Regents, The University Of Texas System Silicon quantum dot optical probes
EP3009147A1 (en) 2014-10-16 2016-04-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for treating resistant glioblastoma
US20180010194A1 (en) 2015-01-12 2018-01-11 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for the Diagnosis of Pancreatic Cancer
WO2017029391A1 (en) 2015-08-20 2017-02-23 INSERM (Institut National de la Santé et de la Recherche Médicale) New method for treating cancer
JP6507969B2 (en) * 2015-09-25 2019-05-08 コニカミノルタ株式会社 Gas detection method and gas detection apparatus
WO2017055322A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of neutrophils in a tissue sample
WO2017055325A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of nk cells in a tissue sample
WO2017055324A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of cells of monocytic origin in a tissue sample
WO2017055321A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of fibroblasts in a tissue sample
WO2017055327A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of endothelial cells in a tissue sample
WO2017055319A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of b cells in a tissue sample
WO2017055320A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of cytotoxic lymphocytes in a tissue sample
WO2017055326A1 (en) 2015-09-29 2017-04-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of myeloid dendritic cells in a tissue sample
WO2017060397A1 (en) 2015-10-09 2017-04-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of subjects suffering from melanoma metastases
EP3362032A4 (en) 2015-10-13 2019-05-01 President and Fellows of Harvard College Systems and methods for making and using gel microspheres
WO2017067944A1 (en) 2015-10-19 2017-04-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of subjects suffering from triple negative breast cancer
AU2016349644B2 (en) 2015-11-06 2022-11-24 Ventana Medical Systems, Inc. Representative diagnostics
US10793909B2 (en) 2015-11-10 2020-10-06 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for predicting the survival time of patients with decompensated alcoholic cirrhosis
US10760135B2 (en) 2016-01-13 2020-09-01 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for predicting pancreatic cancer treatment response
WO2017182834A1 (en) 2016-04-19 2017-10-26 INSERM (Institut National de la Santé et de la Recherche Médicale) New method for treating resistant glioblastoma
WO2017202962A1 (en) 2016-05-24 2017-11-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
US11060147B2 (en) 2016-06-14 2021-07-13 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for predicting acute severe colitis treatment response
WO2018011107A1 (en) 2016-07-11 2018-01-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of er-alpha 46 in methods and kits for assessing the status of breast cancer
WO2018011166A2 (en) 2016-07-12 2018-01-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for quantifying the population of myeloid dendritic cells in a tissue sample
WO2018046736A1 (en) 2016-09-12 2018-03-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of patients suffering from cancer
WO2018046738A1 (en) 2016-09-12 2018-03-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of patients suffering from cancer
WO2018054960A1 (en) 2016-09-21 2018-03-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting and treating resistance to chemotherapy in npm-alk(+) alcl
EP3515453A1 (en) 2016-09-22 2019-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for reprograming immune environment in a subject in need thereof
WO2018122245A1 (en) 2016-12-28 2018-07-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting the survival time of patients suffering from cms3 colorectal cancer
WO2018122249A1 (en) 2016-12-28 2018-07-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of patients suffering from a microsatellite stable colorectal cancer
WO2018146239A1 (en) 2017-02-10 2018-08-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Biomarker for outcome in aml patients
WO2018162404A1 (en) 2017-03-06 2018-09-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Biomarker for outcome in aml patients
CN106868158B (en) * 2017-03-17 2019-08-27 广东省生态环境技术研究所 A kind of detection method and detection kit of salmonella
CN106868157B (en) * 2017-03-17 2019-08-27 广东省生态环境技术研究所 A kind of detection method and detection kit of staphylococcus aureus
WO2018172540A1 (en) 2017-03-24 2018-09-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Method to predict the progression of alzheimer's disease
WO2018178171A1 (en) 2017-03-29 2018-10-04 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for assessing pregnancy outcome
WO2018189215A1 (en) 2017-04-12 2018-10-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the survival time of a patient suffering from hepatocellular carcinoma
CN108982430B (en) * 2017-05-31 2020-09-29 北京大学 Kit and method for marking bacterial flora sample and application
CN107340279B (en) * 2017-06-30 2019-11-08 中国农业科学院农业质量标准与检测技术研究所 A kind of aptamer, kit and method that can detect mercury and silver ion simultaneously
WO2019038219A1 (en) 2017-08-21 2019-02-28 INSERM (Institut National de la Santé et de la Recherche Médicale) New prognostic method of pancreatic cancer
WO2019043138A1 (en) 2017-09-01 2019-03-07 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the outcome of a cancer
CN111683897A (en) * 2017-11-03 2020-09-18 华盛顿大学 Digital nucleic acid amplification using encoded particles
WO2019092269A1 (en) 2017-11-13 2019-05-16 F. Hoffmann-La Roche Ag Devices for sample analysis using epitachophoresis
CN107988335B (en) * 2017-12-22 2021-08-24 嘉兴雅康博生物技术有限公司 Loop-shaped LNA probe for point mutation detection and application thereof
WO2019207030A1 (en) 2018-04-26 2019-10-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
WO2019229489A1 (en) 2018-05-31 2019-12-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of mir-146a-5p and mir-186 as biomarkers of osteoarthritis
CN108872173B (en) * 2018-06-29 2020-12-15 郑州轻工业学院 Fluorescence-enhanced aptamer sensor and preparation method and application thereof
US20200102556A1 (en) * 2018-09-28 2020-04-02 California Institute Of Technology Efficient combinatorial bead barcoding
WO2020089432A1 (en) 2018-11-02 2020-05-07 INSERM (Institut National de la Santé et de la Recherche Médicale) New prognostic method of pancreatic cancer
WO2020089428A1 (en) 2018-11-02 2020-05-07 INSERM (Institut National de la Santé et de la Recherche Médicale) New prognostic method of pancreatic cancer
CN113574386A (en) 2019-01-03 2021-10-29 国家医疗保健研究所 Methods and pharmaceutical compositions for enhancing CD8+ T cell dependent immune responses in cancer patients
US20220119516A1 (en) 2019-01-16 2022-04-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Variants of erythroferrone and their use
WO2020165370A1 (en) 2019-02-13 2020-08-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
WO2020182932A1 (en) 2019-03-13 2020-09-17 INSERM (Institut National de la Santé et de la Recherche Médicale) New gene signatures for predicting survival time in patients suffering from renal cell carcinoma
WO2020193740A1 (en) 2019-03-28 2020-10-01 INSERM (Institut National de la Santé et de la Recherche Médicale) New strategy for treating pancreatic cancer
US20220177978A1 (en) 2019-04-02 2022-06-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting and preventing cancer in patients having premalignant lesions
EP3956474A1 (en) 2019-04-18 2022-02-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the treatment and prognosis of cancer
WO2020216832A1 (en) 2019-04-24 2020-10-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the response of antipsychotic drugs
US20220325268A1 (en) 2019-05-14 2022-10-13 Roche Sequencing Solutions, Inc Devices and methods for sample analysis
WO2020229521A1 (en) 2019-05-14 2020-11-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for inhibiting or reducing bacterial biofilms on a surface
WO2021001539A1 (en) 2019-07-04 2021-01-07 INSERM (Institut National de la Santé et de la Recherche Médicale) New strategy to detect and treat eosinophilic fasciitis
WO2021044012A1 (en) 2019-09-05 2021-03-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Method of treatment and pronostic of acute myeloid leukemia
WO2021063968A1 (en) 2019-09-30 2021-04-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Method and composition for diagnosing chronic obstructive pulmonary disease
CA3157889A1 (en) 2019-10-17 2021-04-22 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for diagnosing nasal intestinal type adenocarcinomas
WO2021170777A1 (en) 2020-02-28 2021-09-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosing, prognosing and managing treatment of breast cancer
EP4121768A1 (en) 2020-03-20 2023-01-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the survival time of a patient suffering from a cancer
JP2023528978A (en) 2020-06-10 2023-07-06 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Methods for treating and preventing cancers such as malignant glioblastoma
WO2021255204A1 (en) 2020-06-18 2021-12-23 INSERM (Institut National de la Santé et de la Recherche Médicale) New strategy for treating pancreatic cancer
WO2022018163A1 (en) 2020-07-22 2022-01-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting survival time in patients suffering from cancer
WO2022064049A1 (en) 2020-09-28 2022-03-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for diagnosing brucella infection
EP4232603A1 (en) 2020-10-20 2023-08-30 Institut National de la Santé et de la Recherche Médicale (INSERM) Method for predicting the response to tnf inhibitors
JP2023548421A (en) 2020-11-06 2023-11-16 インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) Methods for diagnosing and treating polycystic ovarian syndrome (PCOS)
WO2022135753A1 (en) 2020-12-21 2022-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for prognosis the humoral response of a subject prior to vaccination
WO2022136252A1 (en) 2020-12-21 2022-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for prognosis the humoral response of a subject prior to vaccination
WO2022152698A1 (en) 2021-01-12 2022-07-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of npdk-d to evaluate cancer prognosis
EP4291897A1 (en) 2021-02-09 2023-12-20 Institut National de la Santé et de la Recherche Médicale (INSERM) New method to pronostic lung cancer
EP4308934A1 (en) 2021-03-17 2024-01-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for diagnosing pancreatic cancer
WO2022207566A1 (en) 2021-03-29 2022-10-06 INSERM (Institut National de la Santé et de la Recherche Médicale) New method to evaluate pancreatic cancer prognosis
WO2022223791A1 (en) 2021-04-23 2022-10-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating cell senescence accumulation related disease
WO2023280790A1 (en) 2021-07-05 2023-01-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
WO2023089159A1 (en) 2021-11-22 2023-05-25 INSERM (Institut National de la Santé et de la Recherche Médicale) New strategy targeting stroma/tumor cell crosstalk to treat a cancer
WO2023144303A1 (en) 2022-01-31 2023-08-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Cd38 as a biomarker and biotarget in t-cell lymphomas
WO2023152133A1 (en) 2022-02-08 2023-08-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for diagnosing colorectal cancer
WO2024061930A1 (en) 2022-09-22 2024-03-28 Institut National de la Santé et de la Recherche Médicale New method to treat and diagnose peripheral t-cell lymphoma (ptcl)

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
DE69128350T2 (en) 1990-06-11 1998-03-26 Nexstar Pharmaceuticals Inc NUCLEIC ACID LIGANDS
GB2276169A (en) 1990-07-05 1994-09-21 Celltech Ltd Antibodies specific for carcinoembryonic antigen
EP0549692A4 (en) 1990-09-21 1993-08-25 Fred Hutchinson Cancer Research Center Protein sequence-specific oligonucleotide sequences
ES2155822T3 (en) 1990-12-06 2001-06-01 Affymetrix Inc COMPOUNDS AND ITS USE IN A BINARY SYNTHESIS STRATEGY.
JPH06508022A (en) 1991-02-21 1994-09-14 ギリアド サイエンシズ,インコーポレイテッド Biomolecule-specific aptamers and production methods
US5663318A (en) * 1991-03-01 1997-09-02 Pegg; Randall Kevin Assay preparation containing capture and detection polynucleotides covalently bound to substrates with a heterobifunctional crosslinking agent
US5994069A (en) * 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
DE69233331T3 (en) 1991-11-22 2007-08-30 Affymetrix, Inc., Santa Clara Combinatorial Polymersynthesis Strategies
US5505928A (en) 1991-11-22 1996-04-09 The Regents Of University Of California Preparation of III-V semiconductor nanocrystals
US5262357A (en) 1991-11-22 1993-11-16 The Regents Of The University Of California Low temperature thin films formed from nanocrystal precursors
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US6077668A (en) * 1993-04-15 2000-06-20 University Of Rochester Highly sensitive multimeric nucleic acid probes
US6048616A (en) 1993-04-21 2000-04-11 Philips Electronics N.A. Corp. Encapsulated quantum sized doped semiconductor particles and method of manufacturing same
WO1995001365A1 (en) * 1993-07-02 1995-01-12 Lynx Therapeutics, Inc. Synthesis of branched nucleic acids
CA2105364A1 (en) * 1993-09-01 1995-03-02 Eric T. Kool Stem-loop oligonucleotides containing parallel and antiparallel binding domains
CA2170264A1 (en) 1993-09-10 1995-03-16 Michael W. Konrad Optical detection of position of oligonucleotides on large dna molecules
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US6071726A (en) * 1994-07-08 2000-06-06 Visible Genetics Inc. Method, reagents and kit for diagnosis and targeted screening for p53 mutations
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US5750341A (en) * 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
AU5665196A (en) * 1995-04-18 1996-11-07 Igen, Inc. Electrochemiluminescence of rare earth metal chelates
US5545531A (en) * 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
US5690807A (en) 1995-08-03 1997-11-25 Massachusetts Institute Of Technology Method for producing semiconductor particles
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US6236144B1 (en) * 1995-12-13 2001-05-22 Gec-Marconi Limited Acoustic imaging arrays
US6562611B1 (en) * 1996-11-29 2003-05-13 Third Wave Technologies, Ins. FEN-1 endonucleases, mixtures and cleavage methods
US5780278A (en) 1996-05-20 1998-07-14 Vanderbilt University IceA gene and related methods
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US5691153A (en) * 1996-09-06 1997-11-25 Creighton University Genetic markers to detect high bone mass
WO1998020143A1 (en) * 1996-11-05 1998-05-14 Abbott Laboratories Reagents and methods useful for detecting diseases of the lung
US6083761A (en) 1996-12-02 2000-07-04 Glaxo Wellcome Inc. Method and apparatus for transferring and combining reagents
US6023540A (en) * 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US6465175B2 (en) 1997-09-04 2002-10-15 Bayer Corporation Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof
US6322901B1 (en) * 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
US5990479A (en) 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US5989823A (en) * 1998-09-18 1999-11-23 Nexstar Pharmaceuticals, Inc. Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
ES2228107T3 (en) 1998-09-18 2005-04-01 Massachusetts Institute Of Technology FLUORESCENT SEMI-CONDUCTING NANOCRISTALS WATER SOLUBLE.
US6617583B1 (en) * 1998-09-18 2003-09-09 Massachusetts Institute Of Technology Inventory control
US6326144B1 (en) * 1998-09-18 2001-12-04 Massachusetts Institute Of Technology Biological applications of quantum dots
CA2345376C (en) * 1998-09-24 2010-03-16 Advanced Research And Technology Institute, Inc. Water-soluble luminescent quantum dots and bioconjugates thereof
US6500650B1 (en) * 1998-10-01 2002-12-31 Variagenics, Inc. Method for identifying polymorphisms
US6114038A (en) * 1998-11-10 2000-09-05 Biocrystal Ltd. Functionalized nanocrystals and their use in detection systems
US5998479A (en) * 1999-02-09 1999-12-07 Bionumerik Pharmaceuticals, Inc. Method of treating adult respiratory syndrome
US6544732B1 (en) * 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
WO2001071043A1 (en) * 2000-03-22 2001-09-27 Quantum Dot Corporation Loop probe hybridization assay for polynucleotide analysis
US6380377B1 (en) * 2000-07-14 2002-04-30 Applied Gene Technologies, Inc. Nucleic acid hairpin probes and uses thereof
JP2016031772A (en) 2014-07-30 2016-03-07 株式会社日立ハイテクファインシステムズ Inspection method and apparatus of heat-assisted magnetic head element

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