IL165511A0 - A process for preparing sulfoxide compounds compounds prepared thereby and pharmaceutical compositions containing the same - Google Patents
A process for preparing sulfoxide compounds compounds prepared thereby and pharmaceutical compositions containing the sameInfo
- Publication number
- IL165511A0 IL165511A0 IL16551104A IL16551104A IL165511A0 IL 165511 A0 IL165511 A0 IL 165511A0 IL 16551104 A IL16551104 A IL 16551104A IL 16551104 A IL16551104 A IL 16551104A IL 165511 A0 IL165511 A0 IL 165511A0
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- pharmaceutical compositions
- same
- compositions containing
- preparing sulfoxide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN489CH2002 | 2002-06-27 | ||
IN493CH2002 | 2002-06-28 | ||
PCT/US2003/020250 WO2004002982A2 (fr) | 2002-06-27 | 2003-06-27 | Procede de preparation de composes sulfoxyde optiquement purs ou optiquement enrichis, notamment de l'esomeprazole amorphe et ses sels |
Publications (1)
Publication Number | Publication Date |
---|---|
IL165511A0 true IL165511A0 (en) | 2006-01-15 |
Family
ID=34196283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16551104A IL165511A0 (en) | 2002-06-27 | 2004-12-02 | A process for preparing sulfoxide compounds compounds prepared thereby and pharmaceutical compositions containing the same |
Country Status (4)
Country | Link |
---|---|
US (1) | US7169793B2 (fr) |
EP (1) | EP1515963B1 (fr) |
IL (1) | IL165511A0 (fr) |
WO (1) | WO2004002982A2 (fr) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5158574A (en) * | 1987-07-20 | 1992-10-27 | Regen Corporation | Prosthetic meniscus |
US5007934A (en) * | 1987-07-20 | 1991-04-16 | Regen Corporation | Prosthetic meniscus |
EA200500673A1 (ru) * | 2002-10-22 | 2005-12-29 | Рэнбакси Лабораториз Лимитед | Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе |
ATE508124T1 (de) * | 2003-03-24 | 2011-05-15 | Eisai R&D Man Co Ltd | Verfahren zur herstellung von amorphem rabeprazole-natrium-salz |
DE602004022337D1 (de) | 2004-04-28 | 2009-09-10 | Hetero Drugs Ltd | Verfahren zur herstellung von pyridinylmethyl-1h-benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere |
ES2338556T3 (es) | 2004-05-28 | 2010-05-10 | Hetero Drugs Limited | Sintesis estereoselectiva novedosa de sulfoxidos de benzimidazol. |
US20050267159A1 (en) * | 2004-05-28 | 2005-12-01 | Aaipharma, Inc. | Magnesium complexes of S-omeprazole |
MXPA06015031A (es) * | 2004-06-24 | 2007-02-08 | Astrazeneca Ab | Nuevo proceso para la preparacion de modificaciones cristalinas para usarse en la preparacion de sal de sodio de esomeprazol. |
WO2006024890A1 (fr) * | 2004-08-30 | 2006-03-09 | Apollo International Limited | Procede ameliore de preparation de rabeprazole sodique sous forme amorphe |
CN101111233A (zh) | 2004-12-23 | 2008-01-23 | 兰贝克赛实验室有限公司 | 稳定的口服苯并咪唑组合物及其制备方法 |
ES2259269B1 (es) | 2005-03-03 | 2007-11-01 | Esteve Quimica, S.A. | Procedimiento para la preparacion de derivados de 2-(2-piridilmetilsulfinil)-bencimidazol opticamente activos. |
US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
US7563812B2 (en) | 2005-06-15 | 2009-07-21 | Hetero Drugs Limited | Amorphous esomeprazole hydrate |
KR100641534B1 (ko) | 2005-07-28 | 2006-11-01 | 한미약품 주식회사 | 에스오메프라졸 및 그의 염의 제조방법 |
US20070043085A1 (en) * | 2005-08-19 | 2007-02-22 | Glenmark Pharmaceuticals Limited | Process for the preparation of amorphous form of neutral esomeprazole |
EP1948637A4 (fr) * | 2005-11-14 | 2010-09-08 | Hetero Drugs Ltd | Procédé d'obtention d'ésoméprazole amorphe |
DE102005061720B3 (de) * | 2005-12-22 | 2006-10-19 | Ratiopharm Gmbh | Enantioselektive Herstellung von Benzimidazolderivaten und ihren Salzen |
EP1801110A1 (fr) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Sel d'arginine d'ésoméprazole |
US7553857B2 (en) * | 2005-12-23 | 2009-06-30 | Lek Pharmaceuticals D.D. | S-omeprazole magnesium |
CH698658B1 (de) * | 2006-04-24 | 2009-09-30 | Mepha Ag | Orale pharmazeutische Formulierung mit schneller Freisetzung für Pyridylmethylsulfinyl-Benzimidazole. |
US7786309B2 (en) * | 2006-06-09 | 2010-08-31 | Apotex Pharmachem Inc. | Process for the preparation of esomeprazole and salts thereof |
WO2008004245A1 (fr) | 2006-07-05 | 2008-01-10 | Lupin Limited | Procédé pour la préparation d'énantiomères optiquement purs ou optiquement enrichis de composés sulfoxydes |
JP2010519284A (ja) | 2007-02-21 | 2010-06-03 | シプラ・リミテッド | エソメプラゾールマグネシウム二水和物の調製方法 |
KR101303813B1 (ko) * | 2007-04-16 | 2013-09-04 | 에스케이케미칼주식회사 | 라세믹 오메프라졸로부터 에스오메프라졸의 개선된제조방법 |
EP2152691B1 (fr) * | 2007-06-07 | 2011-11-23 | Aurobindo Pharma Limited | Procédé amélioré pour préparer un inhibiteur de la pompe à protons optiquement actif |
EP2106397B1 (fr) | 2007-09-25 | 2011-11-16 | Hetero Drugs Limited | Procédé de préparation d'ésoméprazole pur sur le plan énantiomère |
US8106210B2 (en) | 2007-10-08 | 2012-01-31 | Hetero Drugs Limited | Polymorphs of esomeprazole salts |
US8911787B2 (en) | 2008-02-26 | 2014-12-16 | Ranbaxy Laboratories Limited | Stable oral benzimidazole compositions and process of preparation thereof |
WO2009145368A1 (fr) * | 2008-05-27 | 2009-12-03 | Sk Chemicals Co., Ltd. | Procédé amélioré de préparation de (s)-oméprazole à partir d'un racémate d'oméprazole à l’aide d'un agent de résolution optique |
WO2010058409A2 (fr) | 2008-11-18 | 2010-05-27 | Hetero Research Foundation | Purification optique d'esoméprazole |
CZ2009172A3 (cs) * | 2009-03-17 | 2010-09-29 | Zentiva, K.S. | Zpusob výroby (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolu |
US20120107248A1 (en) * | 2009-07-08 | 2012-05-03 | Mayo Foundation For Medical Education And Research | Imaging gastrointestinal volumes and motility |
EP2499125B1 (fr) | 2009-11-12 | 2016-01-27 | Hetero Research Foundation | Procédé de dédoublement de l'oméprazole |
KR20120114356A (ko) | 2010-02-12 | 2012-10-16 | 에스티브 퀴미카 에스.에이. | 에스오메프라졸 나트륨염의 제조공정 |
FR2959509B1 (fr) | 2010-05-03 | 2012-07-13 | Prod Chim Auxiliaires Et De Synthese | Phase precurseur et son utilisation pour preparer le sel de magnesium tetrahydrate d'un enantiomere d'omeprazole |
CA2824063C (fr) | 2011-01-09 | 2020-02-18 | Anp Technologies, Inc. | Agregats polymeres ramifies induits par des molecules hydrophobes et leur utilisation |
CN102321071B (zh) * | 2011-07-20 | 2013-01-23 | 江苏奥赛康药业股份有限公司 | 一种高纯度埃索美拉唑钠的工业化生产方法 |
CN102321072B (zh) * | 2011-08-08 | 2013-07-03 | 天津市汉康医药生物技术有限公司 | 埃索美拉唑钠半水化合物 |
CN102964337A (zh) * | 2012-12-20 | 2013-03-13 | 南京洵安医药科技有限公司 | 高光学纯度埃索美拉唑生产方法 |
EP2929885A1 (fr) | 2014-04-11 | 2015-10-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Combinaisons pharmaceutiques de rivaroxaban et d'inhibiteurs de la pompe à protons |
EP2933002A1 (fr) | 2014-04-11 | 2015-10-21 | Sanovel Ilac Sanayi ve Ticaret A.S. | Compositions pharmaceutiques comprenants de dabigratan et des inhibiteurs de la pompe à protons |
CN104447737A (zh) * | 2014-11-05 | 2015-03-25 | 沈阳化工大学 | 一种泰妥拉唑的手性拆分分离方法 |
CN111635393A (zh) * | 2020-06-28 | 2020-09-08 | 江苏吴中医药集团有限公司 | 一种艾司奥美拉唑钠的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
SE510666C2 (sv) | 1996-12-20 | 1999-06-14 | Astra Ab | Nya Kristallmodifikationer |
SE510650C2 (sv) | 1997-05-30 | 1999-06-14 | Astra Ab | Ny förening |
US6369087B1 (en) * | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6262085B1 (en) * | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
-
2003
- 2003-06-27 EP EP03762106A patent/EP1515963B1/fr not_active Expired - Lifetime
- 2003-06-27 WO PCT/US2003/020250 patent/WO2004002982A2/fr active IP Right Grant
- 2003-06-27 US US10/608,781 patent/US7169793B2/en not_active Expired - Fee Related
-
2004
- 2004-12-02 IL IL16551104A patent/IL165511A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2004002982A3 (fr) | 2004-06-10 |
WO2004002982A2 (fr) | 2004-01-08 |
EP1515963A2 (fr) | 2005-03-23 |
US7169793B2 (en) | 2007-01-30 |
EP1515963B1 (fr) | 2007-02-14 |
US20040077869A1 (en) | 2004-04-22 |
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