IL163953A0 - Bicyclic heterocyclic compounds and pharmaceuticalcompositions containing the same - Google Patents
Bicyclic heterocyclic compounds and pharmaceuticalcompositions containing the sameInfo
- Publication number
- IL163953A0 IL163953A0 IL16395303A IL16395303A IL163953A0 IL 163953 A0 IL163953 A0 IL 163953A0 IL 16395303 A IL16395303 A IL 16395303A IL 16395303 A IL16395303 A IL 16395303A IL 163953 A0 IL163953 A0 IL 163953A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- heterocyclic compounds
- bicyclic heterocyclic
- pharmaceuticalcompositions
- pharmaceuticalcompositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36273202P | 2002-03-08 | 2002-03-08 | |
PCT/US2003/007240 WO2003075858A2 (en) | 2002-03-08 | 2003-03-07 | Bicyclic heterocycles for the treatment of diabetes and other diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
IL163953A0 true IL163953A0 (en) | 2005-12-18 |
Family
ID=27805219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16395303A IL163953A0 (en) | 2002-03-08 | 2003-03-07 | Bicyclic heterocyclic compounds and pharmaceuticalcompositions containing the same |
Country Status (9)
Country | Link |
---|---|
US (1) | US7196108B2 (ja) |
EP (1) | EP1487446A4 (ja) |
JP (1) | JP2005525371A (ja) |
AU (1) | AU2003223233A1 (ja) |
BR (1) | BR0308278A (ja) |
CA (1) | CA2478765A1 (ja) |
IL (1) | IL163953A0 (ja) |
TW (1) | TWI277415B (ja) |
WO (1) | WO2003075858A2 (ja) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA200200311A1 (ru) | 1999-08-31 | 2002-08-29 | Максиа Фармасьютикалз, Инк. | Бензилиден-тиазолидиндионы и аналоги и их применение для лечения диабета |
MXPA03008117A (es) * | 2001-03-07 | 2004-11-12 | Incyte San Diego Inc | Derivados heterociclicos para el tratamiento del cancer y otras enfermedades proliferativas. |
EP1377559A4 (en) * | 2001-03-08 | 2005-09-28 | Incyte San Diego Inc | MOLECULES ACTIVATING AN RXR RECEPTOR |
US20030083357A1 (en) * | 2001-08-17 | 2003-05-01 | Magnus Pfahl | Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia |
US7102000B2 (en) * | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
WO2004001385A2 (en) * | 2002-06-25 | 2003-12-31 | Helicon Therapeutics, Inc. | Altering memory by affecting staufen function |
US7696193B2 (en) | 2002-12-20 | 2010-04-13 | Glaxo Group Limited | Benzazepine derivatives for the treatment of neurological disorders |
AU2004232326A1 (en) * | 2003-04-18 | 2004-11-04 | Incyte San Diego Incorporated | Substituted isochroman compounds for the treatment of metabolic disorders, cancer and other diseases |
US7122700B2 (en) | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
WO2006116165A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
CN101316821A (zh) * | 2005-09-30 | 2008-12-03 | 詹森药业有限公司 | 作为rxr激动剂用于治疗异常脂肪血症、高胆固醇血症和糖尿病的二氢-[1h]-喹啉-2-酮衍生物 |
WO2010135524A1 (en) | 2009-05-22 | 2010-11-25 | Exelixis, Inc. | Benzoxazepines based p13k/mt0r inhibitors against proliferative diseases |
CN102459248A (zh) | 2009-05-26 | 2012-05-16 | 埃克塞里艾克西斯公司 | 作为PI3K/mTOR抑制剂的苯并氧杂环庚三烯以及它们使用与制造方法 |
US8952034B2 (en) | 2009-07-27 | 2015-02-10 | Gilead Sciences, Inc. | Fused heterocyclic compounds as ion channel modulators |
AU2011272787B2 (en) | 2010-07-02 | 2015-06-18 | Gilead Sciences, Inc. | Fused heterocyclic compounds as ion channel modulators |
WO2012031015A1 (en) * | 2010-09-01 | 2012-03-08 | The Regents Of The University Of California | Cell culture screen for agents that control adipogenesis and myofibroblast differentiation |
WO2012153775A1 (ja) | 2011-05-10 | 2012-11-15 | 国立大学法人神戸大学 | Ras機能阻害作用を有するチオキソチアゾリジン誘導体 |
NZ716420A (en) | 2011-05-10 | 2017-05-26 | Gilead Sciences Inc | Fused heterocyclic compounds as sodium channel modulators |
NO3175985T3 (ja) | 2011-07-01 | 2018-04-28 | ||
TW201837023A (zh) | 2011-07-01 | 2018-10-16 | 美商基利科學股份有限公司 | 作為離子通道調節劑之稠合雜環化合物 |
US10494402B2 (en) | 2012-11-25 | 2019-12-03 | The Regents Of The University Of California | Peptides that stimulate subcutaneous adipogenesis |
US10844102B2 (en) | 2014-05-28 | 2020-11-24 | The Regents Of The University Of California | Peptides, compositions, and methods for stimulating subcutaneous adipogenesis |
SG11202009438UA (en) | 2018-04-18 | 2020-11-27 | Constellation Pharmaceuticals Inc | Modulators of methyl modifying enzymes, compositions and uses thereof |
CA3100977A1 (en) | 2018-05-21 | 2019-11-28 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
Family Cites Families (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4051842A (en) | 1975-09-15 | 1977-10-04 | International Medical Corporation | Electrode and interfacing pad for electrical physiological systems |
DE2626348C3 (de) | 1976-06-11 | 1980-01-31 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Implantierbare Dosiereinrichtung |
JPS5538359A (en) | 1978-09-12 | 1980-03-17 | Hamari Yakuhin Kogyo Kk | Preparation of 2-(3-benzoylphenyl)-propionic acid |
US4383529A (en) | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
IL72684A (en) | 1984-08-14 | 1989-02-28 | Israel State | Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs |
US4668506A (en) | 1985-08-16 | 1987-05-26 | Bausch & Lomb Incorporated | Sustained-release formulation containing and amino acid polymer |
US4713244A (en) | 1985-08-16 | 1987-12-15 | Bausch & Lomb Incorporated | Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1 -C4) polar solvent |
US4931279A (en) | 1985-08-16 | 1990-06-05 | Bausch & Lomb Incorporated | Sustained release formulation containing an ion-exchange resin |
CA1325222C (en) | 1985-08-23 | 1993-12-14 | Lederle (Japan), Ltd. | Process for producing 4-biphenylylacetic acid |
EP0304493B1 (en) | 1987-03-11 | 1992-09-02 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Hydroxystyrene derivatives |
US5330998A (en) | 1988-03-08 | 1994-07-19 | Pfizer Inc. | Thiazolidinedione derivatives as hypoglycemic agents |
US5223522A (en) | 1988-03-08 | 1993-06-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
IE940525L (en) | 1988-05-25 | 1989-11-25 | Warner Lambert Co | Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents |
AU660701B2 (en) | 1991-07-22 | 1995-07-06 | Pfizer Inc. | Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives |
DE69329278T2 (de) | 1992-04-22 | 2001-08-09 | Ligand Pharmaceuticals, Inc. | Retinoid-x rezeptor selektive verbindungen |
US5780676A (en) | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
EP0915090A1 (en) | 1992-09-10 | 1999-05-12 | Eli Lilly And Company | Compounds useful as hypoglycemic agents and for treating Alzheimer's disease |
AU700706B2 (en) | 1992-11-25 | 1999-01-14 | Ligand Pharmaceuticals, Inc. | RXR homodimer formation and bridged bicyclic aromatic compounds and their use in modulating gene expression |
EP0745063B1 (en) | 1994-02-17 | 1999-03-24 | American Home Products Corporation | Substituted biphenyl derivatives as phosphodiesterase inhibitors |
US5691376A (en) | 1994-02-17 | 1997-11-25 | American Home Products Corporation | Substituted biphenyl derivatives |
US5520752A (en) * | 1994-06-20 | 1996-05-28 | The United States Of America As Represented By The Secretary Of The Army | Composite solders |
JPH09136877A (ja) | 1995-06-16 | 1997-05-27 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及び用途 |
EP0850067A4 (en) | 1995-07-17 | 1999-12-15 | Cird Galderma | METHOD FOR CANCER TREATMENT USING 6- (3- (1-ADAMANTYL) -4-HYDROXYPHENYL) 2 NAPHTALINE CARBONIC ACID |
EP0844997A1 (en) | 1996-06-19 | 1998-06-03 | Dr. Reddy's Research Foundation | Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation |
CN1279902C (zh) | 1996-07-08 | 2006-10-18 | 盖尔德马研究及发展公司 | 引起程序性细胞死亡的金刚烷基衍生物及其在制备抗癌药物中的应用 |
CA2300813A1 (en) | 1997-08-21 | 1999-03-04 | Hiroyuki Odaka | Anti-inflammatory agent |
WO1999024415A1 (fr) | 1997-11-12 | 1999-05-20 | Institute Of Medicinal Molecular Design, Inc. | Agonistes du recepteur du retinoide |
US6235996B1 (en) * | 1998-01-28 | 2001-05-22 | International Business Machines Corporation | Interconnection structure and process module assembly and rework |
US6262044B1 (en) | 1998-03-12 | 2001-07-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPASES) |
US6331633B1 (en) | 1998-05-08 | 2001-12-18 | Calyx Therapeutics Inc. | Heterocyclic analogs of diphenylethylene compounds |
EP1128832A4 (en) | 1998-08-21 | 2003-03-05 | Viropharma Inc | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS AND RELATED DISEASES |
WO2000018748A1 (en) | 1998-09-30 | 2000-04-06 | Roche Diagnostics Gmbh | Rhodanine derivatives for the treatment and prevention of metabolic bone disorders |
WO2000032598A1 (en) | 1998-12-04 | 2000-06-08 | Structural Bioinformatics Inc. | Methods and compositions for treating inflammatory diseases utilizing inhibitors of tumor necrosis factor activity |
AU3958200A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
EA200200311A1 (ru) | 1999-08-31 | 2002-08-29 | Максиа Фармасьютикалз, Инк. | Бензилиден-тиазолидиндионы и аналоги и их применение для лечения диабета |
IL144229A (en) | 1999-11-12 | 2006-10-05 | Fujimoto Brothers Co Ltd | New history of N) –2– cyanoimino) thiazolidine – 4 – on |
FR2812876B1 (fr) | 2000-08-08 | 2002-09-27 | Galderma Res & Dev | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar-gamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
MXPA03008117A (es) | 2001-03-07 | 2004-11-12 | Incyte San Diego Inc | Derivados heterociclicos para el tratamiento del cancer y otras enfermedades proliferativas. |
EP1377559A4 (en) | 2001-03-08 | 2005-09-28 | Incyte San Diego Inc | MOLECULES ACTIVATING AN RXR RECEPTOR |
US7348359B2 (en) | 2001-03-14 | 2008-03-25 | Eli Lilly And Company | Retinoid X receptor modulators |
US6838442B2 (en) | 2001-04-04 | 2005-01-04 | Ortho-Mcneil Pharmaceutical, Inc. | Combination therapy comprising glucose reabsorption inhibitors and retinoid-X receptor modulators |
US20030083357A1 (en) | 2001-08-17 | 2003-05-01 | Magnus Pfahl | Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia |
WO2003043998A1 (en) * | 2001-11-15 | 2003-05-30 | Incyte San Diego Incorporated | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases |
TW200304375A (en) | 2001-12-06 | 2003-10-01 | Maxia Pharmaceuticals Inc | 2-Substituted thiazolidinone and oxazolidinone derivatives for the inhibition of phosphatases and the treatment of cancer |
US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
US7102000B2 (en) | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
US20050014767A1 (en) | 2003-01-29 | 2005-01-20 | Magnus Pfahl | Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases |
AU2004232326A1 (en) | 2003-04-18 | 2004-11-04 | Incyte San Diego Incorporated | Substituted isochroman compounds for the treatment of metabolic disorders, cancer and other diseases |
-
2003
- 2003-03-06 US US10/384,391 patent/US7196108B2/en not_active Expired - Fee Related
- 2003-03-07 AU AU2003223233A patent/AU2003223233A1/en not_active Abandoned
- 2003-03-07 WO PCT/US2003/007240 patent/WO2003075858A2/en not_active Application Discontinuation
- 2003-03-07 IL IL16395303A patent/IL163953A0/xx unknown
- 2003-03-07 EP EP03719363A patent/EP1487446A4/en not_active Withdrawn
- 2003-03-07 TW TW092105026A patent/TWI277415B/zh not_active IP Right Cessation
- 2003-03-07 JP JP2003574134A patent/JP2005525371A/ja active Pending
- 2003-03-07 BR BR0308278-4A patent/BR0308278A/pt not_active IP Right Cessation
- 2003-03-07 CA CA002478765A patent/CA2478765A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7196108B2 (en) | 2007-03-27 |
EP1487446A2 (en) | 2004-12-22 |
JP2005525371A (ja) | 2005-08-25 |
WO2003075858A2 (en) | 2003-09-18 |
WO2003075858A3 (en) | 2004-03-18 |
EP1487446A4 (en) | 2006-04-19 |
TWI277415B (en) | 2007-04-01 |
TW200304814A (en) | 2003-10-16 |
AU2003223233A2 (en) | 2003-09-22 |
US20040034004A1 (en) | 2004-02-19 |
CA2478765A1 (en) | 2003-09-18 |
BR0308278A (pt) | 2005-02-09 |
AU2003223233A1 (en) | 2003-09-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL163953A0 (en) | Bicyclic heterocyclic compounds and pharmaceuticalcompositions containing the same | |
IL166802A0 (en) | Heterocyclic aromatic compounds and pharmaceuticalcompositions containing the same | |
AU2003291310A8 (en) | Fused heterocyclic compounds and use thereof | |
IL164455A0 (en) | Heterocyclic compounds and pharmaceutical compositions containing the same | |
PL377087A1 (pl) | Związki heterocykliczne | |
EP1499306A4 (en) | BICYCLIC AMIDE | |
IL174128A0 (en) | Heterocyclic compounds and pharmaceutical compositions containing the same | |
IL163940A0 (en) | Aryl substituted pyrimidines and the use thereof | |
GB0229742D0 (en) | Novel compounds and uses thereof | |
IL174249A0 (en) | Heterocyclic compounds and pharmaceutical compositions containing the same | |
EP1575495A4 (en) | COMPOUNDS AND METHODS | |
GB0221513D0 (en) | Novel compounds and processes | |
GB0220214D0 (en) | Compounds and their use | |
EP1476425A4 (en) | Heterocyclic Aryl Sulphonamidocyclic Compounds | |
GB0120818D0 (en) | Heterocyclic compounds | |
PL376659A1 (pl) | Skondensowane związki heterocykliczne | |
GB0221438D0 (en) | Processes and compounds | |
GB0227906D0 (en) | Compounds and their use | |
GB0230134D0 (en) | Compounds and their use | |
GB0230281D0 (en) | Compounds and their use | |
GB0218031D0 (en) | Compounds and their use | |
GB0220215D0 (en) | Compounds and their use | |
IL165445A0 (en) | Heterocyclic compounds and pharmaceutical compositions containing the same | |
EP1576092A4 (en) | COMPOUNDS AND METHODS | |
AU2002357594A1 (en) | Nitrogen-containing heterocyclic compounds and use thereof |