IL163688A0 - 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and theiruse as antibacterial agents - Google Patents
3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and theiruse as antibacterial agentsInfo
- Publication number
- IL163688A0 IL163688A0 IL16368803A IL16368803A IL163688A0 IL 163688 A0 IL163688 A0 IL 163688A0 IL 16368803 A IL16368803 A IL 16368803A IL 16368803 A IL16368803 A IL 16368803A IL 163688 A0 IL163688 A0 IL 163688A0
- Authority
- IL
- Israel
- Prior art keywords
- theiruse
- cyclyl
- methyl
- nitrogen
- membered ring
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36095702P | 2002-02-28 | 2002-02-28 | |
PCT/GB2003/000785 WO2003072575A1 (en) | 2002-02-28 | 2003-02-25 | 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents |
Publications (1)
Publication Number | Publication Date |
---|---|
IL163688A0 true IL163688A0 (en) | 2005-12-18 |
Family
ID=27766248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16368803A IL163688A0 (en) | 2002-02-28 | 2003-02-25 | 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and theiruse as antibacterial agents |
Country Status (20)
Country | Link |
---|---|
US (1) | US7473699B2 (zh) |
EP (1) | EP1497286A1 (zh) |
JP (1) | JP2005524661A (zh) |
KR (1) | KR20040087329A (zh) |
CN (1) | CN1649866A (zh) |
AR (1) | AR040399A1 (zh) |
AU (1) | AU2003207340A1 (zh) |
BR (1) | BR0308056A (zh) |
CA (1) | CA2477344A1 (zh) |
CO (1) | CO5601011A2 (zh) |
IL (1) | IL163688A0 (zh) |
IS (1) | IS7427A (zh) |
MX (1) | MXPA04008312A (zh) |
NO (1) | NO20043950L (zh) |
NZ (1) | NZ535592A (zh) |
PL (1) | PL372191A1 (zh) |
RU (1) | RU2004129276A (zh) |
TW (1) | TW200304821A (zh) |
WO (1) | WO2003072575A1 (zh) |
ZA (1) | ZA200406812B (zh) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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IL160739A0 (en) | 2001-09-11 | 2004-08-31 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline as antibacterial agents |
WO2003035073A1 (en) | 2001-10-25 | 2003-05-01 | Astrazeneca Ab | Isoxazoline derivatives useful as antimicrobials |
US7091196B2 (en) | 2002-09-26 | 2006-08-15 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using same |
CA2507628A1 (en) * | 2002-11-28 | 2004-06-10 | Astrazeneca Ab | Oxazolidinones as antibacterial agents |
GB0306357D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
GB0306358D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
WO2004099199A1 (en) * | 2003-05-06 | 2004-11-18 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
CA2528089C (en) | 2003-06-03 | 2015-11-24 | Rib-X Pharmaceuticals, Inc. | Biaryl heterocyclic compounds and methods of making and using the same |
US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
KR20060113625A (ko) | 2003-07-02 | 2006-11-02 | 머크 앤드 캄파니 인코포레이티드 | 시클로프로필기 치환된 옥사졸리디논 항생제 및 그의유도체 |
WO2005042523A1 (en) * | 2003-11-03 | 2005-05-12 | Il-Dong Pharm. Co., Ltd. | A novel oxazolidinone derivative and manufacturing process thereof |
TW200526649A (en) | 2003-12-17 | 2005-08-16 | Rib X Pharmaceuticals Inc | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
CN102816194A (zh) | 2004-02-27 | 2012-12-12 | 瑞伯-X医药品有限公司 | 大环化合物以及其制作和使用方法 |
WO2005116022A1 (en) * | 2004-05-25 | 2005-12-08 | Astrazeneca Ab | 3- `4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents |
EP1753755A1 (en) * | 2004-05-25 | 2007-02-21 | AstraZeneca AB | 3- {4- (pyridin-3-yl) phenyl} -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents |
GB0411596D0 (en) * | 2004-05-25 | 2004-06-30 | Astrazeneca Ab | Chemical process |
WO2006043121A1 (en) * | 2004-10-20 | 2006-04-27 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
PT1877415E (pt) * | 2005-05-02 | 2010-12-09 | Baseclick Gmbh | Novas estratégias de marcação para a detecção sensível de analitos |
ATE496914T1 (de) | 2005-06-08 | 2011-02-15 | Rib X Pharmaceuticals Inc | Verfahren zur synthese von triazolen |
WO2007000644A1 (en) | 2005-06-29 | 2007-01-04 | Pharmacia & Upjohn Company Llc | Homomorpholine oxazolidinones as antibacterial agents |
DK2034839T3 (en) | 2006-06-30 | 2017-12-04 | Sloan-Kettering Institute For Cancer Res | TREATMENT OF NEURODEGENERATIVE DISEASES BY INHIBITION OF HSP90 |
JPWO2009044777A1 (ja) | 2007-10-02 | 2011-02-10 | 財団法人乙卯研究所 | 7員ヘテロ環を有するオキサゾリジノン誘導体 |
ES2744907T3 (es) | 2008-10-10 | 2020-02-26 | Merck Sharp & Dohme | Compuestos usados en la síntesis de oxazolidinonas |
EP2393808B1 (en) * | 2009-02-03 | 2019-05-08 | Merck Sharp & Dohme Corp. | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
BR112012008019A2 (pt) | 2009-10-07 | 2016-03-01 | Sloan Kettering Inst Cancer | derivados de purina úteis como inibidores de hsp90 |
EP2508530A1 (en) | 2011-03-28 | 2012-10-10 | Rheinische Friedrich-Wilhelms-Universität Bonn | Purification of triphosphorylated oligonucleotides using capture tags |
BR112013025634A2 (pt) | 2011-04-05 | 2016-07-19 | Sloan Kettering Inst Cancer | inibidores de hsp90 |
EP2694506B1 (en) | 2011-04-05 | 2017-09-20 | Sloan-kettering Institute For Cancer Research | Hsp90 inhibitors |
WO2012137225A1 (en) * | 2011-04-08 | 2012-10-11 | Sphaera Pharma Pvt. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
CN103086973A (zh) * | 2013-01-23 | 2013-05-08 | 大连理工大学 | 一种基于端炔的吡唑类化合物的制备方法 |
KR102511898B1 (ko) | 2015-07-17 | 2023-03-20 | 더 글로벌 얼라이언스 포 티비 드러그 디벨롭먼트, 잉크. | 항미생물 요법을 위한 치환된 페닐옥사졸리디논 |
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GB1222708A (en) * | 1968-10-22 | 1971-02-17 | Delalande Sa | Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation |
CA1260948A (en) | 1984-12-05 | 1989-09-26 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents |
MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
GB9521508D0 (en) | 1995-10-20 | 1995-12-20 | Zeneca Ltd | Chemical compounds |
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GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
GB9604301D0 (en) | 1996-02-29 | 1996-05-01 | Zeneca Ltd | Chemical compounds |
GB9609919D0 (en) | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
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CA2395648A1 (en) | 2000-02-10 | 2001-08-16 | Pharmacia & Upjohn Company | Oxazolidinone thioamides with piperazine amide substituents |
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US6277868B1 (en) * | 2000-08-31 | 2001-08-21 | Abbott Laboratories | Oxazolidinone chemotherapeutic agents |
GB0108793D0 (en) | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
GB0108764D0 (en) | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
GB0108794D0 (en) | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compound |
ATE332299T1 (de) | 2001-04-07 | 2006-07-15 | Astrazeneca Ab | Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika |
GB0113300D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Purification process |
GB0113299D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Chemical process & intermediates |
GB0113298D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Purification process and intermediates |
GB0113297D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Chemical Process |
GB0121490D0 (en) | 2001-09-05 | 2001-10-24 | Smithkline Beecham Plc | Ciompounds |
IL160739A0 (en) | 2001-09-11 | 2004-08-31 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline as antibacterial agents |
WO2003035073A1 (en) | 2001-10-25 | 2003-05-01 | Astrazeneca Ab | Isoxazoline derivatives useful as antimicrobials |
DE60210654T2 (de) | 2001-10-25 | 2007-01-25 | Astrazeneca Ab | Aryl substituierte oxazolidinone mit antibacterieller activität |
WO2003072576A2 (en) * | 2002-02-28 | 2003-09-04 | Astrazeneca Ab | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them |
GB0227701D0 (en) | 2002-11-28 | 2003-01-08 | Astrazeneca Ab | Chemical compounds |
MXPA05005651A (es) | 2002-11-28 | 2005-07-27 | Astrazeneca Ab | Derivados de oxazolidinona y/o isoxazolina como agentes antibacterianos. |
CA2507628A1 (en) | 2002-11-28 | 2004-06-10 | Astrazeneca Ab | Oxazolidinones as antibacterial agents |
GB0229521D0 (en) | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
GB0229522D0 (en) | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
GB0229526D0 (en) | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
GB0229518D0 (en) | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
TW200500360A (en) | 2003-03-01 | 2005-01-01 | Astrazeneca Ab | Hydroxymethyl compounds |
GB0306357D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
GB0306358D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
-
2003
- 2003-02-25 AU AU2003207340A patent/AU2003207340A1/en not_active Abandoned
- 2003-02-25 RU RU2004129276/04A patent/RU2004129276A/ru not_active Application Discontinuation
- 2003-02-25 WO PCT/GB2003/000785 patent/WO2003072575A1/en active Application Filing
- 2003-02-25 CA CA002477344A patent/CA2477344A1/en not_active Abandoned
- 2003-02-25 MX MXPA04008312A patent/MXPA04008312A/es unknown
- 2003-02-25 IL IL16368803A patent/IL163688A0/xx unknown
- 2003-02-25 NZ NZ535592A patent/NZ535592A/en unknown
- 2003-02-25 JP JP2003571281A patent/JP2005524661A/ja active Pending
- 2003-02-25 PL PL03372191A patent/PL372191A1/xx not_active Application Discontinuation
- 2003-02-25 KR KR10-2004-7013454A patent/KR20040087329A/ko not_active Application Discontinuation
- 2003-02-25 US US10/506,020 patent/US7473699B2/en not_active Expired - Fee Related
- 2003-02-25 CN CNA038091712A patent/CN1649866A/zh active Pending
- 2003-02-25 BR BR0308056-0A patent/BR0308056A/pt not_active IP Right Cessation
- 2003-02-25 EP EP03704812A patent/EP1497286A1/en not_active Withdrawn
- 2003-02-27 TW TW092104245A patent/TW200304821A/zh unknown
- 2003-02-28 AR AR20030100689A patent/AR040399A1/es unknown
-
2004
- 2004-08-25 CO CO04083221A patent/CO5601011A2/es not_active Application Discontinuation
- 2004-08-26 ZA ZA200406812A patent/ZA200406812B/en unknown
- 2004-08-27 IS IS7427A patent/IS7427A/is unknown
- 2004-09-21 NO NO20043950A patent/NO20043950L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MXPA04008312A (es) | 2004-11-26 |
NO20043950L (no) | 2004-10-13 |
KR20040087329A (ko) | 2004-10-13 |
CN1649866A (zh) | 2005-08-03 |
AU2003207340A1 (en) | 2003-09-09 |
ZA200406812B (en) | 2005-09-12 |
AR040399A1 (es) | 2005-04-06 |
CO5601011A2 (es) | 2006-01-31 |
US20050119292A1 (en) | 2005-06-02 |
RU2004129276A (ru) | 2005-06-10 |
US7473699B2 (en) | 2009-01-06 |
JP2005524661A (ja) | 2005-08-18 |
BR0308056A (pt) | 2004-12-07 |
TW200304821A (en) | 2003-10-16 |
EP1497286A1 (en) | 2005-01-19 |
IS7427A (is) | 2004-08-27 |
WO2003072575A1 (en) | 2003-09-04 |
PL372191A1 (en) | 2005-07-11 |
NZ535592A (en) | 2006-07-28 |
CA2477344A1 (en) | 2003-09-04 |
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