IL161686A0 - Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents - Google Patents

Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents

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Publication number
IL161686A0
IL161686A0 IL16168602A IL16168602A IL161686A0 IL 161686 A0 IL161686 A0 IL 161686A0 IL 16168602 A IL16168602 A IL 16168602A IL 16168602 A IL16168602 A IL 16168602A IL 161686 A0 IL161686 A0 IL 161686A0
Authority
IL
Israel
Prior art keywords
therapeutic agents
combinations
necrosis factor
tumor necrosis
ligand receptor
Prior art date
Application number
IL16168602A
Other languages
English (en)
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of IL161686A0 publication Critical patent/IL161686A0/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
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  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
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  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
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IL16168602A 2001-11-01 2002-10-25 Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents IL161686A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34640201P 2001-11-01 2001-11-01
US39147802P 2002-06-24 2002-06-24
PCT/US2002/034420 WO2003038043A2 (en) 2001-11-01 2002-10-25 Combinations of dr5 antibody and other therapeutic agents

Publications (1)

Publication Number Publication Date
IL161686A0 true IL161686A0 (en) 2004-09-27

Family

ID=26994839

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16168602A IL161686A0 (en) 2001-11-01 2002-10-25 Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents
IL161686A IL161686A (en) 2001-11-01 2004-04-29 Use of a soluble monoclonal antibody that specifically binds trail receptor dr5 in the manufacture of pharmaceutical compositions targeting cells expressing dr5

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL161686A IL161686A (en) 2001-11-01 2004-04-29 Use of a soluble monoclonal antibody that specifically binds trail receptor dr5 in the manufacture of pharmaceutical compositions targeting cells expressing dr5

Country Status (21)

Country Link
EP (1) EP1506285B1 (hu)
JP (1) JP4663232B2 (hu)
KR (1) KR20040081422A (hu)
CN (1) CN100506277C (hu)
AT (1) ATE491019T1 (hu)
AU (1) AU2002360307B2 (hu)
BR (1) BRPI0213846B8 (hu)
CA (1) CA2465314C (hu)
CO (1) CO5650175A2 (hu)
DE (1) DE60238560D1 (hu)
HK (1) HK1068914A1 (hu)
HU (1) HU230378B1 (hu)
IL (2) IL161686A0 (hu)
MX (1) MXPA04004184A (hu)
NO (1) NO333828B1 (hu)
NZ (2) NZ533164A (hu)
PL (1) PL216750B1 (hu)
RO (1) RO123525B1 (hu)
RU (1) RU2313368C2 (hu)
WO (1) WO2003038043A2 (hu)
ZA (1) ZA200403573B (hu)

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TWI318983B (en) 2000-05-02 2010-01-01 Uab Research Foundation An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
US8071740B2 (en) * 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
WO2002094880A1 (en) 2001-05-18 2002-11-28 Kirin Beer Kabushiki Kaisha Anti-trail-r antibodies
US7252994B2 (en) 2001-07-03 2007-08-07 Genentech, Inc. Human DR4 antibodies and uses thereof
EP2277887A3 (en) 2001-10-19 2011-02-16 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
AU2008201431B2 (en) * 2002-11-27 2011-11-24 Irm, Llc Methods and compositions for inducing Apoptosis in cancer cells
BR0316737A (pt) * 2002-11-27 2005-12-13 Irm Llc Métodos e composições para induzir apoptose em células cancerosas
US20060228331A1 (en) 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
WO2005037306A1 (en) * 2003-10-17 2005-04-28 Novo Nordisk A/S Combination therapy
KR20070010046A (ko) * 2004-04-06 2007-01-19 제넨테크, 인크. Ｄｒ5 항체 및 그의 용도
CN101035912A (zh) 2004-08-06 2007-09-12 健泰科生物技术公司 使用生物标志的测定法和方法
CA2575755C (en) 2004-08-06 2014-04-08 Genentech, Inc. Assays and methods using biomarkers
NZ553174A (en) * 2004-09-08 2010-03-26 Genentech Inc Methods of using death receptor ligands Apo2L/Trail and CD20 antibodies
EP1802660A2 (en) * 2004-09-08 2007-07-04 Genentech, Inc. Methods of using death receptor ligands and cd20 antibodies
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
AU2011259844B2 (en) * 2005-02-02 2012-11-01 The Uab Research Foundation Agents and Methods Related to Reducing Resistance to Apoptosis- inducing Death Receptor Agonists
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