IL160527A0 - Enzymatic process for the preparation of substituted 2-amino-3 (2-aminophenylsulfanyl)-propionic acid - Google Patents

Enzymatic process for the preparation of substituted 2-amino-3 (2-aminophenylsulfanyl)-propionic acid

Info

Publication number
IL160527A0
IL160527A0 IL16052702A IL16052702A IL160527A0 IL 160527 A0 IL160527 A0 IL 160527A0 IL 16052702 A IL16052702 A IL 16052702A IL 16052702 A IL16052702 A IL 16052702A IL 160527 A0 IL160527 A0 IL 160527A0
Authority
IL
Israel
Prior art keywords
sup
preparation
aminophenylsulfanyl
amino
substituted
Prior art date
Application number
IL16052702A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL160527A0 publication Critical patent/IL160527A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/36—Seven-membered rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Peptides Or Proteins (AREA)
IL16052702A 2001-09-25 2002-09-19 Enzymatic process for the preparation of substituted 2-amino-3 (2-aminophenylsulfanyl)-propionic acid IL160527A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01122906 2001-09-25
PCT/EP2002/010511 WO2003029477A1 (en) 2001-09-25 2002-09-19 Enzymatic process for the preparation of substituted 2-amino-3-(2-amino-phenylsulfanyl)-propionic acid

Publications (1)

Publication Number Publication Date
IL160527A0 true IL160527A0 (en) 2004-07-25

Family

ID=8178714

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16052702A IL160527A0 (en) 2001-09-25 2002-09-19 Enzymatic process for the preparation of substituted 2-amino-3 (2-aminophenylsulfanyl)-propionic acid
IL160527A IL160527A (en) 2001-09-25 2004-02-23 Enzymatic process for the preparation of substituted 2 - amino - 3 (2 - aminophenylsulfanyl) -propionic acid and intermediates therefor and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL160527A IL160527A (en) 2001-09-25 2004-02-23 Enzymatic process for the preparation of substituted 2 - amino - 3 (2 - aminophenylsulfanyl) -propionic acid and intermediates therefor and uses thereof

Country Status (15)

Country Link
US (1) US7011960B2 (xx)
EP (1) EP1434870B1 (xx)
JP (1) JP4359142B2 (xx)
KR (1) KR100882972B1 (xx)
CN (1) CN100413972C (xx)
AT (1) ATE349545T1 (xx)
CA (1) CA2461296C (xx)
DE (1) DE60217145T2 (xx)
DK (1) DK1434870T3 (xx)
ES (1) ES2278061T3 (xx)
HU (1) HU228360B1 (xx)
IL (2) IL160527A0 (xx)
JO (1) JO2426B1 (xx)
MX (1) MXPA04002694A (xx)
WO (1) WO2003029477A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8765817B1 (en) 2008-12-03 2014-07-01 Arrowhead Center, Inc. Selective inhibitors of EG5 motors and methods of use
US8349899B1 (en) 2008-12-03 2013-01-08 Arrowhead Center, Inc. Selective inhibitors of EG5 motors and methods of use
EP3067430B1 (en) * 2013-11-01 2020-08-12 Glytech, Inc. Method for producing d-form or l-form amino acid derivative having thiol group
CN104404098A (zh) * 2014-12-15 2015-03-11 苏州汉酶生物技术有限公司 一种硫辛酸的生物制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2804892A1 (de) * 1977-02-09 1978-08-10 Procter & Gamble Verfahren zur herstellung von l-threonin und dessen n-acylderivat
DE3438189A1 (de) * 1984-10-18 1986-04-24 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung aromatisch substituierter l-aminosaeuren
CN87108140A (zh) * 1987-12-17 1988-10-19 山西省生物研究所 D-α氨基酸类物质的制造方法
US5106750A (en) * 1988-08-30 1992-04-21 G. D. Searle & Co. Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents
US5108916A (en) * 1989-06-05 1992-04-28 Rhone-Poulenc Rorer, S.A. Process for stereoselectively hydrolyzing, transesterifying or esterifying with immobilized isozyme of lipase from candida rugosa
DE4009891A1 (de) * 1990-03-28 1991-10-02 Guenter Erich Prof Dr Jeromin Verfahren zur herstellung von optisch aktiven alkoholen und optisch aktiven kohlensaeurediestern mit hilfe von lipasen
CN1071434A (zh) * 1991-07-17 1993-04-28 史密丝克莱恩比彻姆公司 逆转录病毒蛋白酶抑制剂
US5215918A (en) * 1992-06-19 1993-06-01 Bend Research, Inc. Enantiomeric enrichment of (R,S)-3-quinuclidinol
DE4445954A1 (de) * 1994-12-22 1996-06-27 Abb Management Ag Verfahren zur Verbrennung von Abfällen
CZ298144B6 (cs) * 1997-11-27 2007-07-04 Lonza Ag Zpusob výroby (1S,4R)- nebo (1R,4S)-4-(2-amino-6-chlor-9-H-purin-9-yl)-2-cyklopenten-1-methanolu
DK1148140T3 (da) * 2000-04-19 2007-01-08 Basilea Pharmaceutica Ag Fremgangsmåde til fremstilling af D-asparaginderivater

Also Published As

Publication number Publication date
ES2278061T3 (es) 2007-08-01
DE60217145T2 (de) 2007-10-25
JP4359142B2 (ja) 2009-11-04
EP1434870A1 (en) 2004-07-07
CA2461296C (en) 2011-07-05
IL160527A (en) 2010-05-31
DE60217145D1 (de) 2007-02-08
ATE349545T1 (de) 2007-01-15
WO2003029477A1 (en) 2003-04-10
KR20040044979A (ko) 2004-05-31
HUP0401500A2 (hu) 2005-02-28
HUP0401500A3 (en) 2005-11-28
CN100413972C (zh) 2008-08-27
DK1434870T3 (da) 2007-04-30
US7011960B2 (en) 2006-03-14
US20030119152A1 (en) 2003-06-26
CN1553959A (zh) 2004-12-08
EP1434870B1 (en) 2006-12-27
MXPA04002694A (es) 2004-06-18
HU228360B1 (en) 2013-03-28
JO2426B1 (en) 2008-04-17
CA2461296A1 (en) 2003-04-10
KR100882972B1 (ko) 2009-02-12
JP2005503830A (ja) 2005-02-10

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