IL160018A0 - Isoxazolopyridinones and use thereof in the treatment of parkinson's disease - Google Patents
Isoxazolopyridinones and use thereof in the treatment of parkinson's diseaseInfo
- Publication number
- IL160018A0 IL160018A0 IL16001802A IL16001802A IL160018A0 IL 160018 A0 IL160018 A0 IL 160018A0 IL 16001802 A IL16001802 A IL 16001802A IL 16001802 A IL16001802 A IL 16001802A IL 160018 A0 IL160018 A0 IL 160018A0
- Authority
- IL
- Israel
- Prior art keywords
- isoxazolopyridinones
- parkinson
- disease
- treatment
- Prior art date
Links
- WJLKGZPFGUBCPD-UHFFFAOYSA-N 1h-[1,2]oxazolo[4,3-b]pyridin-3-one Chemical class C1=CN=C2C(=O)ONC2=C1 WJLKGZPFGUBCPD-UHFFFAOYSA-N 0.000 title 1
- 208000018737 Parkinson disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0119911.6A GB0119911D0 (en) | 2001-08-15 | 2001-08-15 | Organic Compounds |
| PCT/EP2002/009134 WO2003015780A2 (en) | 2001-08-15 | 2002-08-14 | Isoxazolopyridinones and use thereof in the treatment of parkinson's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL160018A0 true IL160018A0 (en) | 2004-06-20 |
Family
ID=9920454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16001802A IL160018A0 (en) | 2001-08-15 | 2002-08-14 | Isoxazolopyridinones and use thereof in the treatment of parkinson's disease |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7087756B2 (https=) |
| EP (1) | EP1418912B1 (https=) |
| JP (1) | JP2005501847A (https=) |
| KR (1) | KR20040029429A (https=) |
| CN (1) | CN100384418C (https=) |
| AR (1) | AR036351A1 (https=) |
| AT (1) | ATE355059T1 (https=) |
| BR (1) | BR0211903A (https=) |
| CA (1) | CA2454762A1 (https=) |
| CO (1) | CO5560566A2 (https=) |
| DE (1) | DE60218484T2 (https=) |
| EC (1) | ECSP044971A (https=) |
| ES (1) | ES2282467T3 (https=) |
| GB (1) | GB0119911D0 (https=) |
| HU (1) | HUP0401325A3 (https=) |
| IL (1) | IL160018A0 (https=) |
| MX (1) | MXPA04001419A (https=) |
| NO (1) | NO20040659L (https=) |
| PE (1) | PE20030356A1 (https=) |
| PL (1) | PL366848A1 (https=) |
| PT (1) | PT1418912E (https=) |
| RU (1) | RU2004107847A (https=) |
| WO (1) | WO2003015780A2 (https=) |
| ZA (1) | ZA200400525B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2451057A1 (en) * | 2001-06-14 | 2002-12-27 | Banyu Pharmaceutical Co., Ltd. | Novel isoxazolopyridone derivatives and use thereof |
| BRPI0511099A (pt) * | 2004-05-14 | 2007-12-26 | Irm Llc | compostos e composições como moduladores de ppar |
| RU2008135762A (ru) * | 2006-02-16 | 2010-03-27 | Де МакЛин Хоспитал Корпорейшн (US) | Способы и композиции для лечения болезни паркинсона |
| US7666888B2 (en) | 2006-07-20 | 2010-02-23 | Amgen Inc. | Substituted azole aromatic heterocycles as inhibitors of 11β-HSD-1 |
| FR2906250B1 (fr) * | 2006-09-22 | 2008-10-31 | Sanofi Aventis Sa | Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique |
| FR2933609B1 (fr) * | 2008-07-10 | 2010-08-27 | Fournier Lab Sa | Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson. |
| CA2749585A1 (en) | 2009-01-13 | 2010-07-22 | Van Andel Research Institute | Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids |
| FR2950053B1 (fr) | 2009-09-11 | 2014-08-01 | Fournier Lab Sa | Utilisation de derives d'indole benzoique comme activateurs de nurr-1, pour le traitement de la maladie de parkinson |
| FR2955110A1 (fr) | 2010-01-08 | 2011-07-15 | Fournier Lab Sa | Nouveaux derives de type pyrrolopyridine benzoique |
| DE102011085038A1 (de) | 2011-10-21 | 2013-04-25 | Tesa Se | Verfahren zur Kapselung einer elektronischen Anordnung |
| JP2016531852A (ja) | 2013-09-25 | 2016-10-13 | ヴァン アンデル リサーチ インスティテュート | 非常に強力なグルココルチコイド |
| KR20170033630A (ko) | 2015-09-17 | 2017-03-27 | (주)다올 | 도로용 경계블럭 |
| CN110382033B (zh) | 2016-10-14 | 2022-04-15 | 范安德尔研究所 | 用于设计高效力糖皮质激素的结构与机制 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7602542L (sv) | 1975-03-14 | 1976-09-15 | Sandoz Ag | 3-(alfa-iminobensyl)-4-hydroxi-2(lh)-pyridoner |
| US4064251A (en) | 1976-06-25 | 1977-12-20 | Sandoz, Inc. | Substituted hydroxy pyridones |
| US4049813A (en) * | 1976-07-15 | 1977-09-20 | Sandoz, Inc. | Substituted isoxazolo pyridinones |
| DE2801190A1 (de) | 1977-01-19 | 1978-07-20 | Sandoz Ag | 3-(alpha-iminobenzyl)-4-hydroxy-2(1h)- pyridon-derivat |
| US4238616A (en) | 1977-01-19 | 1980-12-09 | Sandoz, Inc. | 3-(Substituted)phenyl-5-(β-hydroxyphenethyl)-N-(alkyl)-isoxazole-4-carboxamides |
| US4113727A (en) * | 1977-04-26 | 1978-09-12 | Sandoz, Inc. | Process for the preparation of substituted isoxazolo[4,5-c]pyridin-4-(5H)-ones |
| CA2451057A1 (en) * | 2001-06-14 | 2002-12-27 | Banyu Pharmaceutical Co., Ltd. | Novel isoxazolopyridone derivatives and use thereof |
-
2001
- 2001-08-15 GB GBGB0119911.6A patent/GB0119911D0/en not_active Ceased
-
2002
- 2002-08-13 AR ARP020103046A patent/AR036351A1/es unknown
- 2002-08-14 JP JP2003520739A patent/JP2005501847A/ja not_active Withdrawn
- 2002-08-14 EP EP02772157A patent/EP1418912B1/en not_active Expired - Lifetime
- 2002-08-14 RU RU2004107847/15A patent/RU2004107847A/ru not_active Application Discontinuation
- 2002-08-14 IL IL16001802A patent/IL160018A0/xx unknown
- 2002-08-14 DE DE60218484T patent/DE60218484T2/de not_active Expired - Lifetime
- 2002-08-14 ES ES02772157T patent/ES2282467T3/es not_active Expired - Lifetime
- 2002-08-14 HU HU0401325A patent/HUP0401325A3/hu unknown
- 2002-08-14 KR KR10-2004-7002124A patent/KR20040029429A/ko not_active Ceased
- 2002-08-14 AT AT02772157T patent/ATE355059T1/de not_active IP Right Cessation
- 2002-08-14 PT PT02772157T patent/PT1418912E/pt unknown
- 2002-08-14 BR BR0211903-0A patent/BR0211903A/pt not_active IP Right Cessation
- 2002-08-14 MX MXPA04001419A patent/MXPA04001419A/es unknown
- 2002-08-14 CA CA002454762A patent/CA2454762A1/en not_active Abandoned
- 2002-08-14 PL PL02366848A patent/PL366848A1/xx not_active Application Discontinuation
- 2002-08-14 PE PE2002000734A patent/PE20030356A1/es not_active Application Discontinuation
- 2002-08-14 CN CNB028159268A patent/CN100384418C/zh not_active Expired - Fee Related
- 2002-08-14 WO PCT/EP2002/009134 patent/WO2003015780A2/en not_active Ceased
- 2002-08-14 US US10/486,569 patent/US7087756B2/en not_active Expired - Fee Related
-
2004
- 2004-01-23 ZA ZA200400525A patent/ZA200400525B/en unknown
- 2004-02-03 EC EC2004004971A patent/ECSP044971A/es unknown
- 2004-02-13 NO NO20040659A patent/NO20040659L/no not_active Application Discontinuation
- 2004-03-12 CO CO04023011A patent/CO5560566A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2454762A1 (en) | 2003-02-27 |
| WO2003015780A8 (en) | 2004-05-21 |
| MXPA04001419A (es) | 2004-05-27 |
| US20040248893A1 (en) | 2004-12-09 |
| CO5560566A2 (es) | 2005-09-30 |
| JP2005501847A (ja) | 2005-01-20 |
| WO2003015780A2 (en) | 2003-02-27 |
| ATE355059T1 (de) | 2006-03-15 |
| CN1635889A (zh) | 2005-07-06 |
| RU2004107847A (ru) | 2005-05-10 |
| ECSP044971A (es) | 2004-03-23 |
| DE60218484D1 (de) | 2007-04-12 |
| ES2282467T3 (es) | 2007-10-16 |
| PE20030356A1 (es) | 2003-05-14 |
| EP1418912B1 (en) | 2007-02-28 |
| US7087756B2 (en) | 2006-08-08 |
| BR0211903A (pt) | 2004-09-21 |
| HUP0401325A3 (en) | 2005-09-28 |
| HUP0401325A2 (hu) | 2004-10-28 |
| NO20040659D0 (no) | 2004-02-13 |
| DE60218484T2 (de) | 2007-11-15 |
| WO2003015780A3 (en) | 2003-11-13 |
| EP1418912A2 (en) | 2004-05-19 |
| KR20040029429A (ko) | 2004-04-06 |
| NO20040659L (no) | 2004-02-13 |
| CN100384418C (zh) | 2008-04-30 |
| PL366848A1 (en) | 2005-02-07 |
| ZA200400525B (en) | 2005-04-01 |
| AR036351A1 (es) | 2004-09-01 |
| PT1418912E (pt) | 2007-05-31 |
| GB0119911D0 (en) | 2001-10-10 |
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