IL156268A0 - Heterocyclic sulfonamide inhibitors of beta amyloid production - Google Patents
Heterocyclic sulfonamide inhibitors of beta amyloid productionInfo
- Publication number
- IL156268A0 IL156268A0 IL15626801A IL15626801A IL156268A0 IL 156268 A0 IL156268 A0 IL 156268A0 IL 15626801 A IL15626801 A IL 15626801A IL 15626801 A IL15626801 A IL 15626801A IL 156268 A0 IL156268 A0 IL 156268A0
- Authority
- IL
- Israel
- Prior art keywords
- beta amyloid
- amyloid production
- heterocyclic sulfonamide
- sulfonamide inhibitors
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25510500P | 2000-12-13 | 2000-12-13 | |
PCT/US2001/048375 WO2002057252A2 (en) | 2000-12-13 | 2001-12-11 | Heterocyclic sulfonamide inhibitors of beta amyloid production |
Publications (1)
Publication Number | Publication Date |
---|---|
IL156268A0 true IL156268A0 (en) | 2004-01-04 |
Family
ID=22966854
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15626801A IL156268A0 (en) | 2000-12-13 | 2001-12-11 | Heterocyclic sulfonamide inhibitors of beta amyloid production |
IL156268A IL156268A (en) | 2000-12-13 | 2003-06-02 | The heterocyclic sequelae of sulfonamide-based beta-amyloid formation |
IL188853A IL188853A0 (en) | 2000-12-13 | 2008-01-17 | Heterocyclic sulfonamide inhibitors of beta amyloid production |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL156268A IL156268A (en) | 2000-12-13 | 2003-06-02 | The heterocyclic sequelae of sulfonamide-based beta-amyloid formation |
IL188853A IL188853A0 (en) | 2000-12-13 | 2008-01-17 | Heterocyclic sulfonamide inhibitors of beta amyloid production |
Country Status (28)
Country | Link |
---|---|
US (5) | US6610734B2 (es) |
EP (1) | EP1341779B1 (es) |
JP (2) | JP2004517892A (es) |
KR (1) | KR100869061B1 (es) |
CN (2) | CN1800176A (es) |
AR (1) | AR035516A1 (es) |
AT (1) | ATE330950T1 (es) |
AU (1) | AU2002245123B2 (es) |
BR (1) | BR0116063A (es) |
CA (1) | CA2436526C (es) |
CY (1) | CY1105441T1 (es) |
DE (1) | DE60121032T2 (es) |
DK (1) | DK1341779T3 (es) |
EA (1) | EA009035B1 (es) |
ES (1) | ES2267853T3 (es) |
HK (1) | HK1059619A1 (es) |
HU (1) | HUP0303857A3 (es) |
IL (3) | IL156268A0 (es) |
MX (1) | MXPA03005255A (es) |
NO (1) | NO328885B1 (es) |
NZ (2) | NZ538100A (es) |
PL (1) | PL365950A1 (es) |
PT (1) | PT1341779E (es) |
SG (1) | SG128491A1 (es) |
SI (1) | SI1341779T1 (es) |
TW (1) | TWI235155B (es) |
WO (1) | WO2002057252A2 (es) |
ZA (1) | ZA200304135B (es) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001240861B2 (en) * | 2000-03-20 | 2006-03-30 | Merck Frosst Canada Ltd | Sulphonamido-substituted bridged bicycloalkyl derivatives |
MXPA03005255A (es) | 2000-12-13 | 2004-10-14 | Wyeth Corp | Inhibidores de produccion de beta-amiloide de sulfonamida heterociclica. |
US6657070B2 (en) | 2000-12-13 | 2003-12-02 | Wyeth | Production of chirally pure α-amino acids and N-sulfonyl α-amino acids |
KR100921641B1 (ko) * | 2001-12-11 | 2009-10-14 | 와이어쓰 | 순수한 키랄성 β-아미노 알콜의 합성방법 |
BR0311767A (pt) * | 2002-06-11 | 2005-03-08 | Wyeth Corp | Compostos inibidores de sulfonamida substituìda da produção de beta amilóide, suas composições e usos |
CA2505098A1 (en) | 2002-11-12 | 2004-05-27 | Merck & Co., Inc. | Phenylcarboxamide beta-secretase inhibitors for the treatment of alzheimer's disease |
NZ542468A (en) * | 2003-03-31 | 2009-01-31 | Wyeth Corp | Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof |
KR20060066057A (ko) * | 2003-06-30 | 2006-06-15 | 다이이찌 세이야꾸 가부시기가이샤 | 복소환 메틸 설폰 유도체 |
WO2005073198A1 (en) | 2004-01-16 | 2005-08-11 | Wyeth | Heterocyclic sulfonamide inhibitors of beta amyloid production containing an azole |
CA2595173A1 (en) | 2005-01-18 | 2006-07-27 | Elan Pharmaceuticals, Inc. | N-substituted heterocyclic sulfonamides |
EP2457901A1 (en) * | 2005-03-14 | 2012-05-30 | High Point Pharmaceuticals, LLC | Benzazole derivatives, compositions, and methods of use as B-secretase inhibitors |
TW200800959A (en) * | 2005-06-10 | 2008-01-01 | Wyeth Corp | Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor |
GB0602951D0 (en) * | 2006-02-14 | 2006-03-29 | Novartis Ag | Organic Compounds |
EP1984347A1 (en) * | 2006-02-17 | 2008-10-29 | Wyeth a Corporation of the State of Delaware | Selective n-sulfonylation of 2-amino trifluoroalkyl substituted alcohols |
AR059518A1 (es) * | 2006-02-17 | 2008-04-09 | Wyeth Corp | Metodos para preparar alcoholes sustituidos con sulfonamidas y sus compuestos intermedios |
US7476762B2 (en) * | 2006-04-21 | 2009-01-13 | Wyeth | Methods for preparing sulfonamide compounds |
US7550629B2 (en) * | 2006-04-21 | 2009-06-23 | Wyeth | Trifluoromethyl-containing phenylsulfonamide beta amyloid inhibitors |
JP2009534385A (ja) * | 2006-04-21 | 2009-09-24 | ワイス | キラル的に純粋なアミノアルコール中間体、それらの誘導体の製造、及びそれらの使用 |
TW200811144A (en) * | 2006-06-09 | 2008-03-01 | Wyeth Corp | Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline |
TW200808740A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof |
TW200808741A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts |
WO2008059238A1 (en) * | 2006-11-17 | 2008-05-22 | Astrazeneca Ab | Benzenesulfonamide compounds as edg-1 antagonists useful in the treatment of cancer |
WO2008064320A2 (en) * | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity |
US20080262228A1 (en) * | 2006-11-28 | 2008-10-23 | Wyeth | Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof |
TW200901974A (en) | 2007-01-16 | 2009-01-16 | Wyeth Corp | Compounds, compositions, and methods of making and using them |
AU2008215948A1 (en) | 2007-02-12 | 2008-08-21 | Merck & Co., Inc. | Piperazine derivatives for treatment of AD and related conditions |
PE20090445A1 (es) * | 2007-07-16 | 2009-05-18 | Wyeth Corp | Inhibidores de produccion de beta amiloide |
PA8789801A1 (es) * | 2007-07-16 | 2009-02-09 | Wyeth Corp | Procesos e intermadiarios para la preparacion de compuestos de silfonamida heterocíclica |
PE20090824A1 (es) * | 2007-07-16 | 2009-07-24 | Wyeth Corp | Proceso para la preparacion de trifluoralquil-fenil sulfonamidas y de sulfonamidas heterociclicas |
US8354446B2 (en) | 2007-12-21 | 2013-01-15 | Ligand Pharmaceuticals Incorporated | Selective androgen receptor modulators (SARMs) and uses thereof |
US20090181932A1 (en) * | 2008-01-11 | 2009-07-16 | Wyeth | COMPOSITIONS CONTAINING O-SULFATE AND O-PHOSPHATE CONTAINING ARYL SULFONAMIDE DERIVATIVES USEFUL AS beta-AMYLOID INHIBITORS |
US8461389B2 (en) | 2008-04-18 | 2013-06-11 | University College Dublin, National University Of Ireland, Dublin | Psycho-pharmaceuticals |
EP3586839A1 (en) | 2008-07-28 | 2020-01-01 | Blanchette Rockefeller Neurosciences, Institute | Pkc-activating compounds for the treatment of neurodegenerative diseases |
KR20120096076A (ko) | 2009-12-17 | 2012-08-29 | 메르크 파텐트 게엠베하 | 스핑고신 키나아제 저해제 |
US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
TWI686193B (zh) | 2013-01-18 | 2020-03-01 | 美商卡爾迪奧克斯爾製藥公司 | 具有增進之治療指數的硝醯基予體 |
CN104370769B (zh) * | 2013-08-14 | 2017-05-31 | 重庆博腾制药科技股份有限公司 | 一种制备羟基金刚烷甘氨酸衍生物的方法 |
EP3613418A1 (en) | 2014-01-17 | 2020-02-26 | Ligand Pharmaceuticals, Inc. | Methods and compositions for modulating hormone levels |
WO2017155890A1 (en) * | 2016-03-11 | 2017-09-14 | Ohio State Innovation Foundation | Novel small molecule antimicrobials |
DE202022106287U1 (de) | 2022-11-09 | 2022-11-21 | Ahmad Salawi | Eine Methode zur Synthese und biologischen Bewertung von neuen Sulfonamid-Analoga |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US656536A (en) * | 1899-12-28 | 1900-08-21 | David Fitzgibbons | Boiler. |
US3376523A (en) * | 1966-12-27 | 1968-04-02 | Univ California | Transient-suppressing magnetic transmission line |
US5594021A (en) | 1993-05-20 | 1997-01-14 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl sulfonamides and derivatives thereof that modulate the activity of endothelin |
US5571821A (en) | 1993-05-20 | 1996-11-05 | Texas Biotechnology Corporation | Sulfonamides and derivatives thereof that modulate the activity of endothelin |
US5514691A (en) | 1993-05-20 | 1996-05-07 | Immunopharmaceutics, Inc. | N-(4-halo-isoxazolyl)-sulfonamides and derivatives thereof that modulate the activity of endothelin |
US5464853A (en) | 1993-05-20 | 1995-11-07 | Immunopharmaceutics, Inc. | N-(5-isoxazolyl)biphenylsulfonamides, N-(3-isoxazolyl)biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin |
US5591761A (en) | 1993-05-20 | 1997-01-07 | Texas Biotechnology Corporation | Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
EP0510700A3 (en) | 1991-04-26 | 1992-12-16 | Takeda Chemical Industries, Ltd. | Azole compounds, their production and use |
GB9110722D0 (en) | 1991-05-17 | 1991-07-10 | Fujisawa Pharmaceutical Co | Amine derivatives |
US5766846A (en) | 1992-07-10 | 1998-06-16 | Athena Neurosciences | Methods of screening for compounds which inhibit soluble β-amyloid peptide production |
US5968942A (en) | 1992-08-25 | 1999-10-19 | G. D. Searle & Co. | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
JP3599287B2 (ja) * | 1993-04-28 | 2004-12-08 | 三菱化学株式会社 | スルホンアミド誘導体 |
US6342610B2 (en) * | 1993-05-20 | 2002-01-29 | Texas Biotechnology Corp. | N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
US6376523B1 (en) | 1994-05-20 | 2002-04-23 | Texas Biotechnology Corporation | Benzenesulfonamides and the use thereof to modulate the activity of endothelin |
CZ184194A3 (en) | 1993-08-09 | 1995-03-15 | Lilly Co Eli | Aspartylprotease inhibitor and method of identifying thereof |
US5519040A (en) | 1994-04-29 | 1996-05-21 | Allergan | Substituted thiazole sulfonamides as antiglaucoma agents |
US5561146A (en) * | 1994-06-10 | 1996-10-01 | Bristol-Myers Squibb Company | Modified guanidino and amidino thrombin inhibitors |
US5624937A (en) | 1995-03-02 | 1997-04-29 | Eli Lilly And Company | Chemical compounds as inhibitors of amyloid beta protein production |
EP0761680A3 (en) * | 1995-09-12 | 1999-05-06 | Ono Pharmaceutical Co., Ltd. | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity |
JPH09136878A (ja) * | 1995-09-12 | 1997-05-27 | Ono Pharmaceut Co Ltd | テトラゾール誘導体 |
ATE377006T1 (de) * | 1995-11-28 | 2007-11-15 | Cephalon Inc | Aus d-aminosäuren abgeleitete cystein- und serinproteasehemmer |
AU1209497A (en) | 1995-12-27 | 1997-07-28 | Takeda Chemical Industries Ltd. | Oxazole derivatives, their production and use |
JPH09235276A (ja) * | 1995-12-27 | 1997-09-09 | Takeda Chem Ind Ltd | オキサゾール誘導体、その製造法および用途 |
US5877193A (en) * | 1996-07-19 | 1999-03-02 | Hoffmann-La Roche Inc. | Use of N-(4-aryl-thiazol-2-yl)-sulfonamides |
CZ16899A3 (cs) | 1996-07-22 | 1999-08-11 | Monsanto Company | Thiolsulfonamidové inhibitory metaloproteázy |
US5703129A (en) | 1996-09-30 | 1997-12-30 | Bristol-Myers Squibb Company | 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of β-amyloid protein production |
KR20000049050A (ko) * | 1996-10-11 | 2000-07-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 술폰아미드 치환된 아스파르트산 인터루킨-1β 전환 효소 억제제 |
US5985930A (en) | 1996-11-21 | 1999-11-16 | Pasinetti; Giulio M. | Treatment of neurodegenerative conditions with nimesulide |
HUP0001383A3 (en) | 1996-11-22 | 2001-11-28 | Lilly Co Eli | N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same and their use |
DE19650196A1 (de) * | 1996-12-04 | 1998-06-10 | Bayer Ag | Thienylsulfonylamino(thio)carbonylverbindungen |
GB9725138D0 (en) * | 1997-11-27 | 1998-01-28 | Pharmacia & Upjohn Spa | Thiophenesulfonamide compounds |
JPH11343279A (ja) | 1998-03-16 | 1999-12-14 | Shionogi & Co Ltd | スルホンアミド誘導体およびそれらを含有するTNF―α産生抑制剤 |
US5981168A (en) | 1998-05-15 | 1999-11-09 | The University Of British Columbia | Method and composition for modulating amyloidosis |
AU1708099A (en) * | 1998-06-03 | 1999-12-20 | Amgen, Inc. | N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres |
US7410995B1 (en) | 1998-08-14 | 2008-08-12 | Gpi Nil Holdings Inc. | N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders |
MXPA01008606A (es) | 1999-02-26 | 2003-05-05 | Merck & Co Inc | Compuestos de sulfonamida novedosos y uso de los mismos. |
US6495578B1 (en) | 1999-04-19 | 2002-12-17 | Shionogi & Co., Ltd. | Sulfonamide derivatives having oxadiazole rings |
EP1088815A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonyl amino acid derivatives |
EP1088821A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives |
AU7997700A (en) * | 1999-10-08 | 2001-04-23 | Du Pont Pharmaceuticals Company | Amino lactam sulfonamides as inhibitors of abeta protein production |
MXPA03005255A (es) | 2000-12-13 | 2004-10-14 | Wyeth Corp | Inhibidores de produccion de beta-amiloide de sulfonamida heterociclica. |
US6657070B2 (en) | 2000-12-13 | 2003-12-02 | Wyeth | Production of chirally pure α-amino acids and N-sulfonyl α-amino acids |
EP1461332A4 (en) | 2001-12-11 | 2009-10-21 | Wyeth Corp | PRODUCTION OF ALPHA-AMINO ACIDS AND CHIRALLY PURE ALPHA-AMINO N-SULFONYL ACIDS |
KR100921641B1 (ko) | 2001-12-11 | 2009-10-14 | 와이어쓰 | 순수한 키랄성 β-아미노 알콜의 합성방법 |
BR0311767A (pt) | 2002-06-11 | 2005-03-08 | Wyeth Corp | Compostos inibidores de sulfonamida substituìda da produção de beta amilóide, suas composições e usos |
NZ542468A (en) * | 2003-03-31 | 2009-01-31 | Wyeth Corp | Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof |
-
2001
- 2001-12-11 MX MXPA03005255A patent/MXPA03005255A/es active IP Right Grant
- 2001-12-11 EP EP01993277A patent/EP1341779B1/en not_active Expired - Lifetime
- 2001-12-11 BR BR0116063-0A patent/BR0116063A/pt not_active Application Discontinuation
- 2001-12-11 CN CNA2005100035919A patent/CN1800176A/zh active Pending
- 2001-12-11 NZ NZ538100A patent/NZ538100A/en unknown
- 2001-12-11 KR KR1020037007928A patent/KR100869061B1/ko not_active IP Right Cessation
- 2001-12-11 DK DK01993277T patent/DK1341779T3/da active
- 2001-12-11 PT PT01993277T patent/PT1341779E/pt unknown
- 2001-12-11 IL IL15626801A patent/IL156268A0/xx active IP Right Review Request
- 2001-12-11 ES ES01993277T patent/ES2267853T3/es not_active Expired - Lifetime
- 2001-12-11 DE DE60121032T patent/DE60121032T2/de not_active Expired - Lifetime
- 2001-12-11 WO PCT/US2001/048375 patent/WO2002057252A2/en active Application Filing
- 2001-12-11 NZ NZ526213A patent/NZ526213A/en unknown
- 2001-12-11 US US10/014,304 patent/US6610734B2/en not_active Expired - Fee Related
- 2001-12-11 EA EA200300674A patent/EA009035B1/ru not_active IP Right Cessation
- 2001-12-11 JP JP2002557933A patent/JP2004517892A/ja not_active Withdrawn
- 2001-12-11 SI SI200130604T patent/SI1341779T1/sl unknown
- 2001-12-11 CN CNB018205186A patent/CN1263750C/zh not_active Expired - Fee Related
- 2001-12-11 CA CA2436526A patent/CA2436526C/en not_active Expired - Fee Related
- 2001-12-11 SG SG200503628A patent/SG128491A1/en unknown
- 2001-12-11 HU HU0303857A patent/HUP0303857A3/hu unknown
- 2001-12-11 PL PL01365950A patent/PL365950A1/xx not_active IP Right Cessation
- 2001-12-11 AT AT01993277T patent/ATE330950T1/de active
- 2001-12-11 AU AU2002245123A patent/AU2002245123B2/en not_active Ceased
- 2001-12-12 TW TW090130721A patent/TWI235155B/zh active
- 2001-12-12 AR ARP010105782A patent/AR035516A1/es not_active Application Discontinuation
-
2003
- 2003-05-28 ZA ZA200304135A patent/ZA200304135B/en unknown
- 2003-06-02 IL IL156268A patent/IL156268A/en not_active IP Right Cessation
- 2003-06-05 US US10/455,674 patent/US6878742B2/en not_active Expired - Fee Related
- 2003-06-11 NO NO20032645A patent/NO328885B1/no not_active IP Right Cessation
-
2004
- 2004-03-02 HK HK04101538A patent/HK1059619A1/xx not_active IP Right Cessation
-
2005
- 2005-03-16 US US11/081,784 patent/US7691884B2/en not_active Expired - Fee Related
-
2006
- 2006-09-14 CY CY20061101305T patent/CY1105441T1/el unknown
-
2008
- 2008-01-17 IL IL188853A patent/IL188853A0/en unknown
-
2009
- 2009-10-09 US US12/576,513 patent/US7842718B2/en not_active Expired - Fee Related
-
2010
- 2010-06-24 JP JP2010144307A patent/JP2010265280A/ja not_active Withdrawn
- 2010-10-19 US US12/907,123 patent/US20110034513A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL188853A0 (en) | Heterocyclic sulfonamide inhibitors of beta amyloid production | |
IL195009A0 (en) | Substituted phenylsulfonamide inhibitors of beta amyloid production | |
NO20022864L (no) | Aminotiazol inhibitorer av syklin uavhengig kinase | |
AR028567A1 (es) | Nuevos derivados de fenil-propargileter | |
EP1537102A4 (en) | INHIBITORS OF PHOSPHOINOSITIDE-3-KINASE BETA | |
NO20022095D0 (no) | Heterocyklisk substituerte pyrazoloner | |
IL142816A0 (en) | SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF Aβ PROTEIN PRODUCTION | |
CY2009001I1 (el) | Νεα μορφη κρυσταλλου του παραγωγου πυρρολιδυλοθειοκαρβαπενεμης | |
ATE355836T1 (de) | Inhibitoren der mucin-synthese | |
DE69902990T2 (de) | Hemmung für Zeitmesser | |
IL150806A0 (en) | Piperidine-and piperazine substituted n-hydroxyformamides as inhibitors of metalloproteinases | |
HK1081185A1 (en) | Acyl derivatives of ziprasidone having neurolepticactivity | |
NO20025659L (no) | Heterocykliske forbindelser | |
PT1206462E (pt) | Compostos heterociclicos para inibicao da angiogenese | |
PT1311424E (pt) | Seccao de linha de producao | |
EE200200389A (et) | Imidasooli uued derivaadid | |
NO20024887D0 (no) | Fremgangsmåte for fremstilling av benzokondenserte heterosykliske forbindelser | |
HUP0302675A3 (en) | New crystalline modifications of lopinavir | |
AU2002220822A1 (en) | For amyloid formation inhibitors | |
EP1430302A4 (en) | Glycosaminoglycan INHIBITORS | |
ATE328506T1 (de) | Schmuckstück | |
TW461265U (en) | Improved structure of pivotal box for spectacles case | |
GB0204088D0 (en) | Novel substituted heterocyclic inhibitors of catechol-o-methyl transperase | |
TW529403U (en) | Improved structure of toothpowder box | |
GB0009043D0 (en) | New autitumoural derivatives of ET-743 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
NP | Permission for amending the patent specification granted (section 66, patents law 1967) |