IL155213A0 - Ketone compounds and compositions for cholesterol management and related uses - Google Patents
Ketone compounds and compositions for cholesterol management and related usesInfo
- Publication number
- IL155213A0 IL155213A0 IL15521301A IL15521301A IL155213A0 IL 155213 A0 IL155213 A0 IL 155213A0 IL 15521301 A IL15521301 A IL 15521301A IL 15521301 A IL15521301 A IL 15521301A IL 155213 A0 IL155213 A0 IL 155213A0
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- ketone compounds
- related uses
- cholesterol management
- cholesterol
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
- -1 Ketone compounds Chemical class 0.000 title 1
- 235000012000 cholesterol Nutrition 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2425—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic containing the structure (RX)(RR'N)P(=Y)-Z-(C)n-Z'-P(=Y)(XR)2 (X = O, S, NR; Y = O, S, electron pair; Z = O, S; Z' = O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/44—Amides thereof
- C07F9/4403—Amides thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4423—Amides of poly (thio)phosphonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
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- Diabetes (AREA)
- Hematology (AREA)
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- Crystallography & Structural Chemistry (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
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- Hospice & Palliative Care (AREA)
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- Urology & Nephrology (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23923200P | 2000-10-11 | 2000-10-11 | |
PCT/US2001/031872 WO2002030860A2 (en) | 2000-10-11 | 2001-10-11 | Ketone compounds and compositions for cholesterol management and related uses |
Publications (1)
Publication Number | Publication Date |
---|---|
IL155213A0 true IL155213A0 (en) | 2003-11-23 |
Family
ID=22901210
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15521301A IL155213A0 (en) | 2000-10-11 | 2001-10-11 | Ketone compounds and compositions for cholesterol management and related uses |
IL155213A IL155213A (en) | 2000-10-11 | 2003-04-03 | Ketones and their use in the preparation of pharmaceuticals |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL155213A IL155213A (en) | 2000-10-11 | 2003-04-03 | Ketones and their use in the preparation of pharmaceuticals |
Country Status (11)
Country | Link |
---|---|
US (1) | US6699910B2 (de) |
EP (1) | EP1326822A2 (de) |
JP (1) | JP2004511453A (de) |
CN (2) | CN1962596A (de) |
AU (2) | AU1313602A (de) |
BR (1) | BRPI0114622B8 (de) |
CA (1) | CA2425311C (de) |
HK (1) | HK1063461A1 (de) |
IL (2) | IL155213A0 (de) |
MX (1) | MXPA03003020A (de) |
WO (1) | WO2002030860A2 (de) |
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US8568766B2 (en) | 2000-08-24 | 2013-10-29 | Gattadahalli M. Anantharamaiah | Peptides and peptide mimetics to treat pathologies associated with eye disease |
US7304093B2 (en) | 2000-10-11 | 2007-12-04 | Esperion Therapeutics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
US20040122091A1 (en) * | 2000-10-11 | 2004-06-24 | Esperion Therapeutics, Inc. | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
US20050003041A1 (en) * | 2001-05-01 | 2005-01-06 | Gerhard Kamil | Application of fluid bed technology in brewing |
CA2480415A1 (en) * | 2002-04-10 | 2003-10-23 | Esperion Therapeutics, Inc. | Mimics of acyl coenzyme-a, compositions thereof, and methods of cholesterol management and related uses |
US20040148013A1 (en) * | 2002-04-18 | 2004-07-29 | Epstein Stephen E | Stent-based delivery statins to prevent restenosis |
US20040048910A1 (en) * | 2002-08-22 | 2004-03-11 | Bove Susan Elizabeth | Method of treating osteoarthritis |
ES2594340T3 (es) | 2003-01-23 | 2016-12-19 | Esperion Therapeutics Inc. | Compuestos de hidroxilo y composiciones para el control del colesterol y utilizaciones correspondientes |
EP1701931B1 (de) | 2003-12-24 | 2018-10-10 | Esperion Therapeutics, Inc. | Ketonverbindungen und zusammensetzungen zur behandlung von cholesterol und deren verwendung |
MX2007013430A (es) | 2005-04-29 | 2008-03-19 | Univ California | Peptidos y peptidos mimeticos para tratar patologias caracterizadas por una respuesta inflamatoria. |
EP2049137A4 (de) | 2006-08-08 | 2013-05-01 | Univ California | Salicylanilide als verstärker der oralen freisetzung therapeutischer peptide |
IL181577A0 (en) * | 2007-02-26 | 2007-07-04 | Jacob Bar Tana | Combination therapy composition and methods for the treatment of cardiovascular disorders and immune-related disorders |
US8557767B2 (en) | 2007-08-28 | 2013-10-15 | Uab Research Foundation | Synthetic apolipoprotein E mimicking polypeptides and methods of use |
AU2008296478B9 (en) | 2007-08-28 | 2015-03-19 | The Uab Research Foundation | Synthetic apolipoprotein E mimicking polypeptides and methods of use |
EP2324126B1 (de) | 2008-08-12 | 2014-04-23 | Zinfandel Pharmaceuticals, Inc. | VERFAHREN ZUR ERKENNUNG VON Alzheimer's KRANKHEITSRISIKOFAKTOREN |
US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
EP2334188A4 (de) * | 2008-08-15 | 2012-08-08 | Burnham Inst Medical Research | Zusammensetzung und verfahren für den entwurf und die entwicklung von metalloenzymhemmern |
WO2011143362A1 (en) | 2010-05-11 | 2011-11-17 | Esperion Therapeutics, Inc. | Dimeric oxidation-resistant apolipoprotein a1 variants |
CN103327974A (zh) | 2010-09-20 | 2013-09-25 | 卡留斯治疗公司 | 用于治疗糖尿病和血脂异常的方法和组合物 |
MX355479B (es) | 2011-01-10 | 2018-04-19 | Zinfandel Pharmaceuticals Inc | Metodos y productos de farmaco para tratar enfermedad de alzheimer. |
DE102011078416A1 (de) * | 2011-06-30 | 2013-01-03 | Henkel Ag & Co. Kgaa | Photolabile Duftspeicherstoffe |
SG11201609084QA (en) | 2014-05-02 | 2016-11-29 | Cerenis Therapeutics Holding Sa | Hdl therapy markers |
CN107074923B (zh) | 2014-07-31 | 2021-08-03 | Uab研究基金会 | Apoe模拟肽及对清除血浆胆固醇的较高效力 |
CN107530307A (zh) | 2015-03-13 | 2018-01-02 | 艾斯柏伦治疗公司 | 包含etc1002和依泽替米贝的固定剂量组合和制剂以及治疗心血管疾病或降低心血管疾病风险的方法 |
MA41793A (fr) | 2015-03-16 | 2018-01-23 | Esperion Therapeutics Inc | Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire |
KR101772440B1 (ko) | 2015-08-31 | 2017-08-30 | 한국식품연구원 | 4-(4-하이드록시-4-메틸펜틸)-3-사이클로-헥센-1-카복스알데하이드를 포함하는 신생혈관형성 촉진용 조성물 |
GB201522302D0 (en) * | 2015-12-17 | 2016-02-03 | Mars Inc | Food product for regulating lipid metabolites |
CN107118098B (zh) * | 2016-02-25 | 2020-07-14 | 中国科学院上海药物研究所 | 一类脂肪酸类化合物、其制备方法及其用途 |
BR112021013045A2 (pt) * | 2018-12-31 | 2021-09-21 | Lupin Limited | Novos sais e forma polimórfica de ácido bempedóico |
CN112437765A (zh) | 2019-06-21 | 2021-03-02 | 艾斯柏伦治疗公司 | 贝派地酸的盐形式及其使用方法 |
CA3143294A1 (en) | 2019-07-26 | 2021-02-04 | Espervita Therapeutics, Inc. | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids useful for the prevention or treatment of disease |
WO2021252607A1 (en) * | 2020-06-12 | 2021-12-16 | Novomer, Inc. | Beta-propiolactone compounds and ring opened beta-propiolactone compounds and uses for same |
TW202245804A (zh) | 2021-01-25 | 2022-12-01 | 美商艾斯佩維他治療學公司 | 官能化長鏈烴單羧酸及二羧酸及其衍生物以及其於預防或治療疾病之用途 |
TW202237073A (zh) * | 2021-01-25 | 2022-10-01 | 美商艾斯佩維他治療學公司 | 官能化長鏈烴單羧酸及二羧酸及其衍生物以及其於預防或治療疾病之用途 |
AU2022381258A1 (en) * | 2021-11-03 | 2024-05-02 | Tuojie Biotech (Shanghai) Co., Ltd. | Substituted phenylpropionic acid derivative and use thereof |
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US3441605A (en) * | 1965-02-17 | 1969-04-29 | Wallace & Tiernan Inc | Diketo-dicarboxylic acids and salts and preparation thereof by alkaline oxidation |
US3930024A (en) | 1969-09-02 | 1975-12-30 | Parke Davis & Co | Pharmaceutical compositions and methods |
US3773946A (en) | 1969-09-02 | 1973-11-20 | Parke Davis & Co | Triglyceride-lowering compositions and methods |
JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
JPS5639033A (en) | 1979-09-04 | 1981-04-14 | Kao Corp | Alpha-mono(methyl-branched alkyl glyceryl ether and skin cosmetic containing the same |
IL64542A0 (en) | 1981-12-15 | 1982-03-31 | Yissum Res Dev Co | Long-chain alpha,omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them |
IT1164254B (it) | 1983-05-30 | 1987-04-08 | Luso Farmaco Inst | 3-(3-idrossibutossi)-1-butanolo e suo metodo di preparazione |
JPS60136512A (ja) | 1983-12-26 | 1985-07-20 | Eisai Co Ltd | 脂質代謝改善剤 |
DE3423166A1 (de) | 1984-06-22 | 1986-01-02 | Epis S.A., Zug | Alpha-, omega-dicarbonsaeuren, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
JP2999579B2 (ja) | 1990-07-18 | 2000-01-17 | 武田薬品工業株式会社 | Dnaおよびその用途 |
US5254589A (en) | 1991-10-15 | 1993-10-19 | Warner-Lambert Company | Sulfonyl urea and carbamate ACAT inhibitors |
IL109431A (en) | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
US5420339A (en) | 1993-11-22 | 1995-05-30 | Warner-Lambert Company | Alpha-aryl or heteroaryl-substituted amide ester ACAT inhibitors |
US5504073A (en) | 1994-07-01 | 1996-04-02 | Warner-Lambert Company | PLA2 inhibitors and their use for inhibition of intestinal cholesterol absorption |
US5578639A (en) | 1994-07-01 | 1996-11-26 | Warner-Lambert Company | PLA2 inhibitors and their use for inhibition of intestinal cholesterol absorption |
US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
GEP20001898B (en) | 1995-11-02 | 2000-01-05 | Warner Lambert Co | Method and Pharmaceutical Composition for Regulating Lipid Concentration with Mam |
US5807846A (en) | 1996-11-14 | 1998-09-15 | Warner-Lambert Company | Phosphonamide ACAT inhibitors |
IL119971A (en) | 1997-01-07 | 2003-02-12 | Yissum Res Dev Co | Pharmaceutical compositions containing dicarboxylic acids and derivatives thereof and some novel dicarboxylic acids |
US6093744A (en) | 1997-04-21 | 2000-07-25 | Warner-Lambert Company | N-acyl sulfamic acid esters useful as hypocholesterolemic agents |
IL121165A0 (en) | 1997-06-26 | 1997-11-20 | Yissum Res Dev Co | Pharmaceutical compositions containing carboxylic acids and derivatives thereof |
DE60020962T2 (de) | 1999-04-28 | 2006-05-24 | Georgetown University | Liganden für metabotropische Glutamat-Rezeptoren |
AU2291001A (en) | 1999-12-23 | 2001-07-03 | Emory University | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states |
-
2001
- 2001-10-11 EP EP01981499A patent/EP1326822A2/de not_active Withdrawn
- 2001-10-11 IL IL15521301A patent/IL155213A0/xx unknown
- 2001-10-11 JP JP2002534250A patent/JP2004511453A/ja not_active Withdrawn
- 2001-10-11 AU AU1313602A patent/AU1313602A/xx active Pending
- 2001-10-11 WO PCT/US2001/031872 patent/WO2002030860A2/en active Application Filing
- 2001-10-11 BR BRPI0114622A patent/BRPI0114622B8/pt not_active IP Right Cessation
- 2001-10-11 MX MXPA03003020A patent/MXPA03003020A/es active IP Right Grant
- 2001-10-11 CN CNA2006101540229A patent/CN1962596A/zh active Pending
- 2001-10-11 AU AU2002213136A patent/AU2002213136B2/en not_active Expired
- 2001-10-11 US US09/976,938 patent/US6699910B2/en not_active Expired - Lifetime
- 2001-10-11 CN CNB018202470A patent/CN1283610C/zh not_active Expired - Lifetime
- 2001-10-11 CA CA2425311A patent/CA2425311C/en not_active Expired - Lifetime
-
2003
- 2003-04-03 IL IL155213A patent/IL155213A/en active IP Right Grant
-
2004
- 2004-08-20 HK HK04106257A patent/HK1063461A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2002213136B2 (en) | 2007-01-04 |
WO2002030860A2 (en) | 2002-04-18 |
WO2002030860A9 (en) | 2003-02-20 |
AU1313602A (en) | 2002-04-22 |
BRPI0114622B1 (pt) | 2016-07-05 |
US20030078239A1 (en) | 2003-04-24 |
CN1962596A (zh) | 2007-05-16 |
CA2425311A1 (en) | 2002-04-18 |
CN1283610C (zh) | 2006-11-08 |
MXPA03003020A (es) | 2003-07-14 |
EP1326822A2 (de) | 2003-07-16 |
US6699910B2 (en) | 2004-03-02 |
BR0114622A (pt) | 2004-06-29 |
CN1479712A (zh) | 2004-03-03 |
CA2425311C (en) | 2011-06-14 |
JP2004511453A (ja) | 2004-04-15 |
IL155213A (en) | 2011-12-29 |
HK1063461A1 (en) | 2004-12-31 |
WO2002030860A3 (en) | 2002-08-15 |
BRPI0114622B8 (pt) | 2021-05-25 |
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