IL153676A0 - Liposomal pharmaceutical compositions - Google Patents
Liposomal pharmaceutical compositionsInfo
- Publication number
- IL153676A0 IL153676A0 IL15367601A IL15367601A IL153676A0 IL 153676 A0 IL153676 A0 IL 153676A0 IL 15367601 A IL15367601 A IL 15367601A IL 15367601 A IL15367601 A IL 15367601A IL 153676 A0 IL153676 A0 IL 153676A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- liposomal pharmaceutical
- compositions
- liposomal
- manufacturing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21555600P | 2000-06-30 | 2000-06-30 | |
US26461601P | 2001-01-26 | 2001-01-26 | |
PCT/CA2001/000925 WO2002002077A2 (en) | 2000-06-30 | 2001-06-29 | Liposomal antineoplastic drugs and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL153676A0 true IL153676A0 (en) | 2003-07-06 |
Family
ID=26910152
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15367601A IL153676A0 (en) | 2000-06-30 | 2001-06-29 | Liposomal pharmaceutical compositions |
IL153676A IL153676A (en) | 2000-06-30 | 2002-12-26 | Liposomal pharmaceutical compositions |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL153676A IL153676A (en) | 2000-06-30 | 2002-12-26 | Liposomal pharmaceutical compositions |
Country Status (12)
Country | Link |
---|---|
US (7) | US7060828B2 (es) |
EP (2) | EP1299085B1 (es) |
JP (3) | JP2004501955A (es) |
CN (1) | CN1245977C (es) |
AT (2) | ATE309787T1 (es) |
AU (3) | AU7038501A (es) |
CA (2) | CA2412790C (es) |
DE (2) | DE60115044T2 (es) |
ES (1) | ES2253398T3 (es) |
IL (2) | IL153676A0 (es) |
MX (1) | MXPA02012817A (es) |
WO (2) | WO2002002077A2 (es) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
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US20040247662A1 (en) * | 1998-06-25 | 2004-12-09 | Dow Steven W. | Systemic immune activation method using nucleic acid-lipid complexes |
US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
US6723338B1 (en) * | 1999-04-01 | 2004-04-20 | Inex Pharmaceuticals Corporation | Compositions and methods for treating lymphoma |
DE60115044T2 (de) * | 2000-06-30 | 2006-08-03 | Inex Pharmaceuticals Corp., Burnaby | Liposomale antineoplastische arzneimittel und deren verwendungen |
US7452550B2 (en) * | 2000-06-30 | 2008-11-18 | Hana Biosciences, Inc. | Liposomal antineoplastic drugs and uses thereof |
EP1424889A4 (en) * | 2001-08-20 | 2008-04-02 | Transave Inc | PROCESS FOR TREATING LUNG CANCERS |
US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
CA2494673A1 (en) * | 2002-08-02 | 2004-07-01 | Transave, Inc. | Platinum aggregates and process for producing the same |
US20060030578A1 (en) * | 2002-08-20 | 2006-02-09 | Neopharm, Inc. | Pharmaceutically active lipid based formulation of irinotecan |
AU2003287526A1 (en) * | 2002-11-06 | 2004-06-03 | Protein-stabilized liposomal formulations of pharmaceutical agents | |
EP1643972A4 (en) * | 2003-06-27 | 2010-01-20 | Smithkline Beecham Corp | STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD |
DE602004021713D1 (de) * | 2003-11-14 | 2009-08-06 | Het Nl Kanker I The Netherland | Pharmazeutische formulierungen mit kurzketten-sphingolipiden und ihre verwendung |
WO2005072776A2 (en) * | 2004-01-30 | 2005-08-11 | Instytut Farmaceutyczny | Liposomal formulations of the antineoplastic agents |
US20050181035A1 (en) * | 2004-02-17 | 2005-08-18 | Dow Steven W. | Systemic immune activation method using non CpG nucleic acids |
CA2559722A1 (en) * | 2004-03-18 | 2005-09-29 | Transave, Inc. | Administration of cisplatin by inhalation |
US20070065522A1 (en) * | 2004-03-18 | 2007-03-22 | Transave, Inc. | Administration of high potency platinum compound formulations by inhalation |
EP1746976B1 (en) | 2004-05-03 | 2017-01-11 | Merrimack Pharmaceuticals, Inc. | Liposomes useful for drug delivery |
ATE450251T1 (de) * | 2004-05-17 | 2009-12-15 | Tekmira Pharmaceuticals Corp | Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung |
AU2005245018A1 (en) * | 2004-05-21 | 2005-12-01 | Transave, Inc. | Treatment of lung diseases and pre-lung disease conditions |
UA85099C2 (en) * | 2004-06-01 | 2008-12-25 | Кабусики Кайся Якулт Хонса | Liposomal irinotecan preparation |
EP1773298A1 (en) * | 2004-08-06 | 2007-04-18 | Biospectrum, Inc. | Multiple layered liposome and preparation method thereof |
CA2582949A1 (en) * | 2004-10-06 | 2006-04-13 | Bc Cancer Agency | Liposomes with improved drug retention for treatment of cancer |
EP1807051A2 (en) * | 2004-11-05 | 2007-07-18 | Inex Pharmaceuticals Corporation | Compositions and methods for stabilizing liposomal camptothecin formulations |
US20060246124A1 (en) * | 2004-11-08 | 2006-11-02 | Pilkiewicz Frank G | Methods of treating cancer with lipid-based platinum compound formulations administered intraperitoneally |
CN100348194C (zh) * | 2005-07-26 | 2007-11-14 | 康辰医药发展有限公司 | 盐酸洛拉曲克的脂质体制剂及其制备方法 |
CN100375621C (zh) * | 2005-11-04 | 2008-03-19 | 唐星 | 长春瑞滨脂质微球注射液及其制备方法 |
US20070190182A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
US9107824B2 (en) * | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
FR2895258B1 (fr) | 2005-12-22 | 2008-03-21 | Aventis Pharma Sa | Combinaison comprenant de la combretastatine et des agents anticancereux |
JP2009535360A (ja) * | 2006-04-26 | 2009-10-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 高分子量神経治療薬の対流増加送達のための組成物および方法 |
WO2008070009A2 (en) * | 2006-12-01 | 2008-06-12 | Alza Corporation | Treating solid tumors and monocytic leukemia using topoisomerase inhibitors in liposomes |
US8067432B2 (en) | 2008-03-31 | 2011-11-29 | University Of Kentucky Research Foundation | Liposomal, ring-opened camptothecins with prolonged, site-specific delivery of active drug to solid tumors |
US20100093873A1 (en) * | 2008-10-02 | 2010-04-15 | Goldfischer Sidney L | Methods of improving therapy of perfluorocarbons (PFC) |
JPWO2010058840A1 (ja) * | 2008-11-20 | 2012-04-19 | テルモ株式会社 | リポソームからの薬物放出手段および放出性評価法 |
EP2642371A1 (en) | 2010-01-14 | 2013-09-25 | BrainLAB AG | Controlling a surgical navigation system |
WO2012058666A2 (en) * | 2010-10-29 | 2012-05-03 | Health Research, Inc. | Novel formulations of water-insoluble chemical compounds and methods of using a formulation of compound fl118 for cancer therapy |
PL226015B1 (pl) | 2011-03-03 | 2017-06-30 | Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną | Liposomowy preparat zawierajacy przeciwnowotworowa substancje aktywna, sposob jego wytwarzania i zawierajaca go kompozycja farmaceutyczna |
US10449193B2 (en) * | 2011-06-03 | 2019-10-22 | Signpath Pharma Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies |
US10117881B2 (en) | 2011-06-03 | 2018-11-06 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies |
US10238602B2 (en) | 2011-06-03 | 2019-03-26 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies |
US10349884B2 (en) * | 2011-06-03 | 2019-07-16 | Sighpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel |
US10532045B2 (en) | 2013-12-18 | 2020-01-14 | Signpath Pharma, Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
US12004868B2 (en) * | 2011-06-03 | 2024-06-11 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
CA2836904C (en) * | 2011-06-03 | 2019-09-24 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current |
US9717724B2 (en) | 2012-06-13 | 2017-08-01 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies |
AU2013202947B2 (en) | 2012-06-13 | 2016-06-02 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
US11291644B2 (en) | 2012-09-04 | 2022-04-05 | Eleison Pharmaceuticals, Llc | Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin |
CA2891656C (en) | 2012-11-20 | 2021-05-04 | Spectrum Pharmaceuticals | Method for the preparation of liposome encapsulated vincristine |
KR102245421B1 (ko) * | 2013-05-30 | 2021-04-29 | 큐라디즘 | 약학적 조성물, 이의 제조방법 및 이의 용도 |
EP3151837B1 (en) | 2014-06-03 | 2023-03-15 | Signpath Pharma, Inc. | Protective effect of dmpc, dmpg, dmpc/dmpg, egpg, lysopg and lysopc against drugs that cause channelopathies |
FI3229776T3 (fi) * | 2014-11-25 | 2023-08-15 | Curadigm Sas | Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt |
US11318131B2 (en) | 2015-05-18 | 2022-05-03 | Ipsen Biopharm Ltd. | Nanoliposomal irinotecan for use in treating small cell lung cancer |
TWI678213B (zh) | 2015-07-22 | 2019-12-01 | 美商史倍壯製藥公司 | 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物 |
WO2017031442A1 (en) | 2015-08-20 | 2017-02-23 | Merrimack Pharmaceuticals, Inc. | Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment |
CN108495629A (zh) | 2015-08-21 | 2018-09-04 | 益普生生物制药有限公司 | 使用包含脂质体伊立替康和奥沙利铂的组合疗法治疗转移性胰腺癌的方法 |
CA2940470C (en) * | 2015-09-18 | 2019-08-20 | Signpath Pharma Inc. | Treatment for glioblastoma |
WO2017066726A1 (en) | 2015-10-16 | 2017-04-20 | Merrimack Pharmaceuticals, Inc. | Stabilizing camptothecin pharmaceutical compositions |
US11433136B2 (en) | 2015-12-18 | 2022-09-06 | The General Hospital Corporation | Polyacetal polymers, conjugates, particles and uses thereof |
WO2017189424A2 (en) | 2016-04-27 | 2017-11-02 | Signpath Pharma, Inc. | Prevention of drug-induced atrio-ventricular block |
JP6978099B2 (ja) | 2016-09-02 | 2021-12-08 | ディセルナ ファーマシューティカルズ インコーポレイテッド | 4’−リン酸アナログ及びそれを含むオリゴヌクレオチド |
MA46709A (fr) | 2016-11-02 | 2019-09-11 | Ipsen Biopharm Ltd | Traitement du cancer gastrique au moyen de polythérapies comprenant de l'oxaliplatine, du 5-fluoruracile (et de la leucovorine) et de l'irinotécan sous forme liposomale |
CN114224840A (zh) | 2017-03-31 | 2022-03-25 | 富士胶片株式会社 | 脂质体组合物及医药组合物 |
EP3752158A4 (en) * | 2018-02-14 | 2022-03-09 | L.E.A.F Holdings Group LLC | GAMMA-POLYGLUTAMATED AMINOPTERINE AND USES THEREOF |
TWI737974B (zh) * | 2018-04-09 | 2021-09-01 | 美商標徑製藥公司 | 用於治療增生性失調的劑量方案 |
EP3773734A4 (en) * | 2018-04-11 | 2022-05-11 | New Mexico Tech University Research Park Corporation | LIPID PRODRUGS FOR USE IN DRUG DELIVERY |
TW202015658A (zh) | 2018-06-20 | 2020-05-01 | 日商富士軟片股份有限公司 | 包含內含藥物之脂質體組成物及免疫檢查點抑制劑之組合醫藥 |
WO2020071349A1 (ja) | 2018-10-01 | 2020-04-09 | 富士フイルム株式会社 | 薬物を内包するリポソーム組成物およびプラチナ製剤を含む組合せ医薬 |
WO2020205473A1 (en) | 2019-03-29 | 2020-10-08 | Decerna Pharmaceuticals, Inc. | Compositions and methods for the treatment of kras associated diseases or disorders |
KR20220004675A (ko) | 2019-05-03 | 2022-01-11 | 다이서나 파마수이티컬, 인크. | 단축 센스 가닥을 갖는 이중 가닥 핵산 억제제 분자 |
CN115461042A (zh) * | 2019-12-20 | 2022-12-09 | 翻译生物公司 | 制备负载mrna的脂质纳米颗粒的改进方法 |
CN115298192A (zh) | 2020-01-15 | 2022-11-04 | 迪克纳制药公司 | 4′-o-亚甲基膦酸酯核酸及其类似物 |
EP4192505A1 (en) | 2020-08-04 | 2023-06-14 | Dicerna Pharmaceuticals, Inc. | Systemic delivery of oligonucleotides |
EP4349337A1 (en) | 2021-05-24 | 2024-04-10 | FUJIFILM Corporation | Anti-tumor agent |
TW202313032A (zh) | 2021-05-24 | 2023-04-01 | 日商富士軟片股份有限公司 | 處置劑 |
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US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
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US5552154A (en) * | 1989-11-06 | 1996-09-03 | The Stehlin Foundation For Cancer Research | Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof |
US5552156A (en) | 1992-10-23 | 1996-09-03 | Ohio State University | Liposomal and micellular stabilization of camptothecin drugs |
EP0721328A4 (en) * | 1993-09-27 | 1997-09-17 | Smithkline Beecham Corp | CAMPTOTHECIN FORMULATIONS |
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DE60115044T2 (de) * | 2000-06-30 | 2006-08-03 | Inex Pharmaceuticals Corp., Burnaby | Liposomale antineoplastische arzneimittel und deren verwendungen |
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-
2001
- 2001-06-29 DE DE60115044T patent/DE60115044T2/de not_active Expired - Lifetime
- 2001-06-29 AU AU7038501A patent/AU7038501A/xx active Pending
- 2001-06-29 US US09/896,811 patent/US7060828B2/en not_active Expired - Lifetime
- 2001-06-29 CN CNB018138187A patent/CN1245977C/zh not_active Expired - Lifetime
- 2001-06-29 EP EP01949169A patent/EP1299085B1/en not_active Expired - Lifetime
- 2001-06-29 AU AU2001270385A patent/AU2001270385B2/en not_active Expired
- 2001-06-29 IL IL15367601A patent/IL153676A0/xx active IP Right Grant
- 2001-06-29 DE DE60115045T patent/DE60115045T2/de not_active Expired - Lifetime
- 2001-06-29 AT AT01949169T patent/ATE309787T1/de not_active IP Right Cessation
- 2001-06-29 US US09/896,812 patent/US7244448B2/en not_active Expired - Lifetime
- 2001-06-29 JP JP2002506699A patent/JP2004501955A/ja not_active Withdrawn
- 2001-06-29 ES ES01949169T patent/ES2253398T3/es not_active Expired - Lifetime
- 2001-06-29 AU AU2001270413A patent/AU2001270413A1/en not_active Abandoned
- 2001-06-29 MX MXPA02012817A patent/MXPA02012817A/es active IP Right Grant
- 2001-06-29 AT AT01949141T patent/ATE309786T1/de not_active IP Right Cessation
- 2001-06-29 CA CA2412790A patent/CA2412790C/en not_active Expired - Lifetime
- 2001-06-29 EP EP01949141A patent/EP1299084B1/en not_active Expired - Lifetime
- 2001-06-29 WO PCT/CA2001/000925 patent/WO2002002077A2/en active IP Right Grant
- 2001-06-29 WO PCT/CA2001/000981 patent/WO2002002078A2/en active IP Right Grant
- 2001-06-29 CA CA2412795A patent/CA2412795C/en not_active Expired - Lifetime
-
2002
- 2002-12-26 IL IL153676A patent/IL153676A/en unknown
-
2004
- 2004-02-27 US US10/788,649 patent/US20040170678A1/en not_active Abandoned
-
2005
- 2005-12-06 US US11/294,826 patent/US20060093662A1/en not_active Abandoned
-
2006
- 2006-05-08 US US11/429,911 patent/US20060269594A1/en not_active Abandoned
-
2010
- 2010-12-09 US US12/963,888 patent/US20110086826A1/en not_active Abandoned
-
2012
- 2012-02-09 JP JP2012025785A patent/JP2012092148A/ja active Pending
- 2012-06-28 US US13/536,325 patent/US20130136787A1/en not_active Abandoned
-
2014
- 2014-02-17 JP JP2014027576A patent/JP2014088444A/ja active Pending
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