IL153097A0 - A process for selectively amplifying nucleic acid sequences - Google Patents
A process for selectively amplifying nucleic acid sequencesInfo
- Publication number
- IL153097A0 IL153097A0 IL15309701A IL15309701A IL153097A0 IL 153097 A0 IL153097 A0 IL 153097A0 IL 15309701 A IL15309701 A IL 15309701A IL 15309701 A IL15309701 A IL 15309701A IL 153097 A0 IL153097 A0 IL 153097A0
- Authority
- IL
- Israel
- Prior art keywords
- nucleic acid
- acid sequences
- amplifying nucleic
- selectively amplifying
- sequences
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/605,192 US6323009B1 (en) | 2000-06-28 | 2000-06-28 | Multiply-primed amplification of nucleic acid sequences |
PCT/US2001/020217 WO2002000934A2 (en) | 2000-06-28 | 2001-06-27 | Multiply-primed amplification of nucleic acid sequences |
Publications (1)
Publication Number | Publication Date |
---|---|
IL153097A0 true IL153097A0 (en) | 2003-06-24 |
Family
ID=24422608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15309701A IL153097A0 (en) | 2000-06-28 | 2001-06-27 | A process for selectively amplifying nucleic acid sequences |
Country Status (9)
Country | Link |
---|---|
US (2) | US6323009B1 (de) |
EP (1) | EP1315833B1 (de) |
JP (1) | JP4718756B2 (de) |
AT (1) | ATE343003T1 (de) |
AU (2) | AU6872501A (de) |
CA (1) | CA2410951A1 (de) |
DE (1) | DE60123980T2 (de) |
IL (1) | IL153097A0 (de) |
WO (1) | WO2002000934A2 (de) |
Families Citing this family (162)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003624A1 (en) * | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
US6261808B1 (en) * | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
US5854033A (en) * | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
DK0862656T3 (da) * | 1995-11-21 | 2001-04-09 | Univ Yale | Unimolekylær segmentamplifikation og -detektering |
US7195871B2 (en) * | 1996-01-24 | 2007-03-27 | Third Wave Technologies, Inc | Methods and compositions for detecting target sequences |
US20080220425A1 (en) * | 1996-01-24 | 2008-09-11 | Third Wave Technologies, Inc. | Methods and Compositions for Detecting Target Sequences |
US20080160524A1 (en) * | 1996-01-24 | 2008-07-03 | Third Wave Technologies, Inc. | Methods and Compositions for Detecting Target Sequences |
US7205129B1 (en) | 2000-02-28 | 2007-04-17 | Qiagen Gmbh | Method for reducing artifacts in nucleic acid amplification |
US20020120409A1 (en) * | 2000-05-19 | 2002-08-29 | Affymetrix, Inc. | Methods for gene expression analysis |
US6531283B1 (en) | 2000-06-20 | 2003-03-11 | Molecular Staging, Inc. | Protein expression profiling |
JP2004502431A (ja) | 2000-06-30 | 2004-01-29 | モレキュラー ステージング,インコーポレイテッド | ロリポッププローブを用いたシグナル増幅 |
WO2002061133A2 (en) | 2000-11-09 | 2002-08-08 | Yale University | Nucleic acid detection using structured probes |
US8507662B2 (en) | 2001-01-19 | 2013-08-13 | General Electric Company | Methods and kits for reducing non-specific nucleic acid amplification |
US6573051B2 (en) * | 2001-03-09 | 2003-06-03 | Molecular Staging, Inc. | Open circle probes with intramolecular stem structures |
DE10119006A1 (de) * | 2001-04-18 | 2002-10-24 | Roche Diagnostics Gmbh | Verfahren zur Verbesserung der Stabilität linearer DNA in zellfreien in vitro Transkriptions/Translations-Systemen |
US20030152942A1 (en) * | 2001-05-09 | 2003-08-14 | Lance Fors | Nucleic acid detection in pooled samples |
US7838270B2 (en) * | 2001-05-22 | 2010-11-23 | The University Of Chicago | Target-dependent transcription using deletion mutants of N4 RNA polymerase |
US6861231B2 (en) * | 2001-08-17 | 2005-03-01 | Qiagen Gmbh | Suppression of cross-reactivity and non-specific binding by antibodies using protein A |
US7297485B2 (en) * | 2001-10-15 | 2007-11-20 | Qiagen Gmbh | Method for nucleic acid amplification that results in low amplification bias |
US6617137B2 (en) * | 2001-10-15 | 2003-09-09 | Molecular Staging Inc. | Method of amplifying whole genomes without subjecting the genome to denaturing conditions |
US6977148B2 (en) * | 2001-10-15 | 2005-12-20 | Qiagen Gmbh | Multiple displacement amplification |
US6977162B2 (en) | 2002-03-01 | 2005-12-20 | Ravgen, Inc. | Rapid analysis of variations in a genome |
US7442506B2 (en) | 2002-05-08 | 2008-10-28 | Ravgen, Inc. | Methods for detection of genetic disorders |
US7727720B2 (en) | 2002-05-08 | 2010-06-01 | Ravgen, Inc. | Methods for detection of genetic disorders |
US7176002B2 (en) * | 2002-05-16 | 2007-02-13 | Applera Corporation | Universal-tagged oligonucleotide primers and methods of use |
US20050118602A1 (en) * | 2002-10-10 | 2005-06-02 | Yin-Xiong Li | Gene profiling of single or multiple cells |
US20040115643A1 (en) * | 2002-12-12 | 2004-06-17 | Lizardi Paul M. | Thermodynamic equilibrium extension of primers |
US7955795B2 (en) * | 2003-06-06 | 2011-06-07 | Qiagen Gmbh | Method of whole genome amplification with reduced artifact production |
JP4886298B2 (ja) * | 2002-12-20 | 2012-02-29 | キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング | 核酸増幅 |
US9487823B2 (en) * | 2002-12-20 | 2016-11-08 | Qiagen Gmbh | Nucleic acid amplification |
US6977153B2 (en) * | 2002-12-31 | 2005-12-20 | Qiagen Gmbh | Rolling circle amplification of RNA |
EP1590470A4 (de) * | 2003-02-03 | 2006-09-27 | Ge Healthcare Bio Sciences | Cdna-amplifikation für expression-profiling |
US7192703B2 (en) | 2003-02-14 | 2007-03-20 | Intel Corporation, Inc. | Biomolecule analysis by rolling circle amplification and SERS detection |
US8043834B2 (en) | 2003-03-31 | 2011-10-25 | Qiagen Gmbh | Universal reagents for rolling circle amplification and methods of use |
CA2521520A1 (en) * | 2003-04-29 | 2004-11-11 | Amersham Biosciences Corp | Multiply-primed amplification of nucleic acid sequences |
US20050202453A1 (en) * | 2003-05-28 | 2005-09-15 | Wen-Yuan Song | Nucleic acid amplification in yeast |
WO2005010159A2 (en) * | 2003-07-17 | 2005-02-03 | Children's Hospital Medical Center | Rolling circle amplification of micro-rna samples |
US20050069926A1 (en) * | 2003-08-01 | 2005-03-31 | Affymetrix, Inc. | Helicase-amplified reverse transcription |
WO2005030995A1 (en) * | 2003-09-23 | 2005-04-07 | University Of Missouri | Methods of synthesizing polynucleotides using thermostable enzymes |
WO2005108608A1 (en) * | 2004-05-10 | 2005-11-17 | Kabushiki Kaisha Dnaform | Method for isolating nucleic acid isoforms |
US20080318217A1 (en) * | 2004-09-14 | 2008-12-25 | Yale University | Identification of Gene Associated with Reading Disability and Uses Therefor |
US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
JP2008513782A (ja) * | 2004-09-17 | 2008-05-01 | パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド | 分子解析のための装置及び方法 |
US20080305142A1 (en) * | 2004-12-11 | 2008-12-11 | Cytogenix, Inc. | Cell Free Biosynthesis of High-Quality Nucleic Acid and Uses Thereof |
US20060252032A1 (en) * | 2005-01-28 | 2006-11-09 | Third Wave Technologies, Inc. | Detection of human herpesviruses |
EP1863908B1 (de) | 2005-04-01 | 2010-11-17 | Qiagen GmbH | Reverse transkription und amplifikation von rna bei simultaner degradierung von dna |
US20070020667A1 (en) * | 2005-06-30 | 2007-01-25 | Ruff David W | Methods and compositions for amplifying nucleic acids |
EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
US7482127B2 (en) * | 2005-11-03 | 2009-01-27 | Third Wave Technologies, Inc. | Nucleic acid detection assays employing blocker oligonucleotides |
US20080057499A1 (en) * | 2006-02-06 | 2008-03-06 | Affymetrix, Inc. | Methods for high specificity whole genome amplification and hybridization |
US20080131875A1 (en) * | 2006-06-07 | 2008-06-05 | Third Wave Technologies, Inc. | Multiplex assays |
US7759062B2 (en) * | 2006-06-09 | 2010-07-20 | Third Wave Technologies, Inc. | T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection |
WO2008021290A2 (en) | 2006-08-09 | 2008-02-21 | Homestead Clinical Corporation | Organ-specific proteins and methods of their use |
ATE522627T1 (de) * | 2006-09-01 | 2011-09-15 | Ventana Med Syst Inc | Verfahren zur herstellung von nukleinsäuresonden |
AU2007307171B2 (en) | 2006-10-04 | 2012-01-19 | Third Wave Technologies, Inc. | Snap-back primers and detectable hairpin structures |
WO2008051928A2 (en) * | 2006-10-23 | 2008-05-02 | The Salk Institute For Biological Studies | Target-oriented whole genome amplification of nucliec acids |
US20080096258A1 (en) * | 2006-10-24 | 2008-04-24 | Christian Korfhage | Rolling circle amplification of circular genomes |
CA2858359C (en) | 2006-11-01 | 2018-04-03 | Ventana Medical Systems, Inc. | Haptens, hapten conjugates, compositions thereof and method for their preparation and use |
US8551704B2 (en) | 2007-02-16 | 2013-10-08 | Pacific Biosciences Of California, Inc. | Controllable strand scission of mini circle DNA |
WO2008118679A1 (en) * | 2007-03-23 | 2008-10-02 | Ge Healthcare Bio-Sciences Corp. | Multiply-primed amplification of circular nucleic acid sequences |
US7682789B2 (en) | 2007-05-04 | 2010-03-23 | Ventana Medical Systems, Inc. | Method for quantifying biomolecules conjugated to a nanoparticle |
WO2008153744A2 (en) | 2007-05-23 | 2008-12-18 | Ventana Medical Systems, Inc. | Polymeric carriers for immunohistochemistry and in situ hybridization |
WO2008151023A2 (en) * | 2007-06-01 | 2008-12-11 | Ibis Biosciences, Inc. | Methods and compositions for multiple displacement amplification of nucleic acids |
CN101802220B (zh) * | 2007-07-26 | 2013-07-31 | 加利福尼亚太平洋生物科学股份有限公司 | 分子冗余测序法 |
US20090227463A1 (en) * | 2008-03-04 | 2009-09-10 | Reif John H | Autonomous in vitro evolution |
KR101419980B1 (ko) | 2008-03-15 | 2014-07-15 | 홀로직, 인크. | 증폭 반응 도중에 핵산 분자를 분석하기 위한 조성물 및 방법 |
JP2011515102A (ja) | 2008-03-28 | 2011-05-19 | パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド | 核酸シーケンシング用組成物及び方法 |
US20090247426A1 (en) * | 2008-03-31 | 2009-10-01 | Pacific Biosciences Of California, Inc. | Focused library generation |
JP2011520460A (ja) * | 2008-05-22 | 2011-07-21 | ジーイー・ヘルスケア・バイオサイエンス・コーポレイション | 一本鎖dna結合タンパク質を用いる向上した核酸増幅 |
CA2720728C (en) | 2008-06-05 | 2018-04-03 | Ventana Medical Systems, Inc. | Compositions comprising nanomaterials and method for using such compositions for histochemical processes |
US20100008939A1 (en) * | 2008-07-09 | 2010-01-14 | General Electric Company | Unprocessed rolling circle amplification product |
KR20100019220A (ko) * | 2008-08-08 | 2010-02-18 | 삼성전자주식회사 | 열순환을 포함하는 다중 치환 증폭에 의하여 표적 핵산 서열을 증폭하는 방법 |
US20100055680A1 (en) * | 2008-08-28 | 2010-03-04 | Perkinelmer Las, Inc. | Genomic dna labeling and amplification |
WO2010027497A2 (en) * | 2008-09-05 | 2010-03-11 | Pacific Biosciences Of California, Inc | Preparations, compositions, and methods for nucleic acid sequencing |
ES2359058B1 (es) | 2009-07-02 | 2012-03-27 | Consejo Superior De Investigaciones Cient�?Ficas (Csic) | Quimera de adn polimerasa del fago ph1 29. |
ES2351294B8 (es) | 2009-07-02 | 2012-06-06 | Consejo Superior De Investigaciones Científicas (Csic) | Metodo para la replicación, amplificación, o secuenciación de un adn molde. |
ES2628739T3 (es) * | 2009-10-15 | 2017-08-03 | Ibis Biosciences, Inc. | Amplificación por desplazamiento múltiple |
US20110195457A1 (en) * | 2010-02-09 | 2011-08-11 | General Electric Company | Isothermal amplification of nucleic acid using primers comprising a randomized sequence and specific primers and uses thereof |
USPP22463P3 (en) * | 2010-02-16 | 2012-01-17 | Menachem Bornstein | Gypsophila plant named ‘Pearl Blossom’ |
US8774488B2 (en) | 2010-03-11 | 2014-07-08 | Cellscape Corporation | Method and device for identification of nucleated red blood cells from a maternal blood sample |
US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
WO2012024658A2 (en) | 2010-08-20 | 2012-02-23 | IntegenX, Inc. | Integrated analysis system |
US20120100549A1 (en) * | 2010-10-01 | 2012-04-26 | Ibis Biosciences, Inc. | Targeted genome amplification methods |
GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
WO2013024173A1 (en) | 2011-08-17 | 2013-02-21 | Technische Universität München | Computer implemented method for identifying regulatory regions or regulatory variations |
US9133509B2 (en) | 2012-03-22 | 2015-09-15 | Lgc Genomics Limited | Polymerase chain reaction detection system |
US9777319B2 (en) | 2012-06-29 | 2017-10-03 | General Electric Company | Method for isothermal DNA amplification starting from an RNA template |
CN104797718B (zh) | 2012-09-12 | 2020-05-08 | 加利福尼亚大学董事会 | 通过单链扩增和测序对单个细胞进行精确基因组测序 |
WO2014074755A1 (en) | 2012-11-07 | 2014-05-15 | Yale University | Assessing risk of reading and language impairment |
AU2014248759B2 (en) | 2013-03-13 | 2020-02-27 | Meso Scale Technologies, Llc. | Improved assay methods |
US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
CN105209532B (zh) | 2013-03-15 | 2017-11-28 | 路博润先进材料公司 | 不含重金属的cpvc组合物 |
US9879313B2 (en) | 2013-06-25 | 2018-01-30 | Prognosys Biosciences, Inc. | Methods and systems for determining spatial patterns of biological targets in a sample |
JP6769869B2 (ja) * | 2013-10-16 | 2020-10-14 | ニユー・イングランド・バイオレイブス・インコーポレイテツド | 強化された特性を有する逆転写酵素 |
KR102497054B1 (ko) | 2014-05-15 | 2023-02-06 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
US10227624B2 (en) | 2014-07-18 | 2019-03-12 | Fluidigm Corporation | Reagents and kit compositions for single-cell whole genome amplification |
CN113186256A (zh) | 2015-04-10 | 2021-07-30 | 空间转录公司 | 生物样本的空间区别、多重核酸分析 |
CN105695571A (zh) * | 2016-01-29 | 2016-06-22 | 苏州金唯智生物科技有限公司 | 一种基于滚环扩增的dna定量方法 |
EP4015647B1 (de) | 2016-02-26 | 2023-08-30 | The Board of Trustees of the Leland Stanford Junior University | Multiplexierte einzelmolekül-rna-visualisierung mit einem zwei-sonden-proximitätsligationssystem |
CN105907752A (zh) * | 2016-05-09 | 2016-08-31 | 湖南农业大学 | 基于体外滚环复制的pcv2毒株感染性克隆构建试剂盒及方法 |
US10350307B2 (en) | 2017-09-18 | 2019-07-16 | General Electric Company | In vivo RNA or protein expression using double-stranded concatemeric DNA including phosphorothioated nucleotides |
CN109971833B (zh) * | 2017-12-28 | 2020-11-20 | 南京金斯瑞生物科技有限公司 | 快速均一化环状dna样本的方法 |
WO2019222708A2 (en) | 2018-05-17 | 2019-11-21 | Meso Scale Technologies, Llc. | Methods for isolating surface marker displaying agents |
US20210382043A1 (en) | 2018-10-23 | 2021-12-09 | Meso Scale Technologies, Llc. | Methods for isolating surface marker displaying agents |
EP3894590A2 (de) | 2018-12-10 | 2021-10-20 | 10X Genomics, Inc. | Verfahren zur verwendung von master/kopie-anordnungen zur räumlichen detektion |
US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
WO2020180645A1 (en) | 2019-03-01 | 2020-09-10 | Meso Scale Technologies, Llc. | Electrochemiluminescent labeled probes for use in immunoassay methods, methods using such and kits comprising same |
WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
EP4025711A2 (de) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Erhöhung der spezifität einer analytbindung |
FI3891300T3 (fi) | 2019-12-23 | 2023-05-10 | 10X Genomics Inc | Menetelmät spatiaalista analyysiä varten rna-templatoitua ligaatiota käyttäen |
US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
WO2021167986A1 (en) | 2020-02-17 | 2021-08-26 | 10X Genomics, Inc. | In situ analysis of chromatin interaction |
JP2023514749A (ja) | 2020-02-21 | 2023-04-07 | 10エックス ジェノミクス インコーポレイテッド | 統合型インサイチュ空間的アッセイのための方法および組成物 |
US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
EP4114966A1 (de) | 2020-03-03 | 2023-01-11 | Pacific Biosciences Of California, Inc. | Verfahren und zusammensetzungen zur sequenzierung von doppelsträngigen nukleinsäuren |
ES2965354T3 (es) | 2020-04-22 | 2024-04-12 | 10X Genomics Inc | Métodos para análisis espacial que usan eliminación de ARN elegido como diana |
WO2021236584A1 (en) | 2020-05-19 | 2021-11-25 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
AU2021275906A1 (en) | 2020-05-22 | 2022-12-22 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
WO2021236929A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
AU2021294334A1 (en) | 2020-06-25 | 2023-02-02 | 10X Genomics, Inc. | Spatial analysis of DNA methylation |
US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
JP2023539360A (ja) | 2020-09-02 | 2023-09-13 | メソ スケール テクノロジーズ エルエルシー | サンプル中の1つ以上の標的分析物を検出するためのキット並びにそれを作製及び使用する方法 |
US20230349920A1 (en) | 2020-09-04 | 2023-11-02 | Meso Scale Technologies, Llc. | Methods for isolating central nervous system surface marker displaying agents |
US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
EP4012046A1 (de) | 2020-12-11 | 2022-06-15 | 10X Genomics, Inc. | Verfahren und zusammensetzungen zur multimodalen in-situ-analyse |
WO2022140028A1 (en) | 2020-12-21 | 2022-06-30 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
CN116848263A (zh) | 2020-12-23 | 2023-10-03 | 10X基因组学有限公司 | 用于分析物检测的方法和组合物 |
US20220228200A1 (en) | 2021-01-19 | 2022-07-21 | 10X Genomics, Inc. | Methods and compositions for internally controlled in situ assays |
US20220235403A1 (en) | 2021-01-26 | 2022-07-28 | 10X Genomics, Inc. | Nucleic acid analog probes for in situ analysis |
US20220282319A1 (en) | 2021-03-03 | 2022-09-08 | 10X Genomics, Inc. | Analyte detection in situ using nucleic acid origami |
EP4323546A1 (de) | 2021-04-16 | 2024-02-21 | Meso Scale Technologies, LLC | Verfahren, zusammensetzungen und kits zum nachweis der hydrolaseenzymaktivität |
EP4330672A1 (de) | 2021-04-26 | 2024-03-06 | Meso Scale Technologies, LLC. | Verfahren zur isolierung und analyse eines zielanalyts, das von einem oberflächenmarker-anzeigemittel eingekapselt ist |
US20220364160A1 (en) | 2021-05-14 | 2022-11-17 | Akoya Biosciences, Inc. | Amplification of RNA Detection Signals in Biological Samples |
EP4347877A1 (de) | 2021-06-01 | 2024-04-10 | 10X Genomics, Inc. | Verfahren und zusammensetzungen zum nachweis von analyten und zur sondenauflösung |
CN117751197A (zh) | 2021-06-02 | 2024-03-22 | 10X基因组学有限公司 | 使用不对称可环化探针的样品分析 |
US20230012607A1 (en) | 2021-07-09 | 2023-01-19 | 10X Genomics, Inc. | Methods for detecting analytes using sparse labelling |
CN117651855A (zh) | 2021-07-13 | 2024-03-05 | 10X基因组学有限公司 | 用于制备具有可控厚度的聚合基质的方法 |
GB202110485D0 (en) | 2021-07-21 | 2021-09-01 | Dnae Diagnostics Ltd | Compositions, kits and methods for sequencing target polynucleotides |
GB202110479D0 (en) | 2021-07-21 | 2021-09-01 | Dnae Diagnostics Ltd | Compositions, kits and methods for sequencing target polynucleotides |
CA3226451A1 (en) | 2021-07-21 | 2023-01-26 | Sam Reed | Method and system comprising a cartridge for sequencing target polynucleotides |
WO2023015192A1 (en) | 2021-08-03 | 2023-02-09 | 10X Genomics, Inc. | Nucleic acid concatemers and methods for stabilizing and/or compacting the same |
EP4326898A1 (de) | 2021-08-16 | 2024-02-28 | 10X Genomics, Inc. | Sonden mit einem geteilten strichcodebereich und verfahren zur verwendung |
WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
WO2023102118A2 (en) | 2021-12-01 | 2023-06-08 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
WO2023108139A2 (en) | 2021-12-10 | 2023-06-15 | 10X Genomics, Inc. | Multi-resolution in situ decoding |
WO2023129898A2 (en) | 2021-12-27 | 2023-07-06 | 10X Genomics, Inc. | Methods and compositions for rolling circle amplification |
WO2023141588A1 (en) | 2022-01-21 | 2023-07-27 | 10X Genomics, Inc. | Multiple readout signals for analyzing a sample |
WO2023164570A1 (en) | 2022-02-23 | 2023-08-31 | Insitro, Inc. | Pooled optical screening and transcriptional measurements of cells comprising barcoded genetic perturbations |
WO2023172915A1 (en) | 2022-03-08 | 2023-09-14 | 10X Genomics, Inc. | In situ code design methods for minimizing optical crowding |
WO2023192302A1 (en) | 2022-03-29 | 2023-10-05 | 10X Genomics, Inc. | Spectral unmixing combined with decoding for super-multiplexed in situ analysis |
WO2023196526A1 (en) | 2022-04-06 | 2023-10-12 | 10X Genomics, Inc. | Methods for multiplex cell analysis |
US20240002902A1 (en) | 2022-05-06 | 2024-01-04 | 10X Genomics, Inc. | Analysis of antigen and antigen receptor interactions |
WO2023220300A1 (en) | 2022-05-11 | 2023-11-16 | 10X Genomics, Inc. | Compositions and methods for in situ sequencing |
WO2023245190A1 (en) | 2022-06-17 | 2023-12-21 | 10X Genomics, Inc. | Catalytic de-crosslinking of samples for in situ analysis |
WO2024081869A1 (en) | 2022-10-14 | 2024-04-18 | 10X Genomics, Inc. | Methods for analysis of biological samples |
Family Cites Families (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US541306A (en) * | 1895-06-18 | Sectional die | ||
US677183A (en) * | 1900-11-30 | 1901-06-25 | Howard W Denham | Wheel-repairing device. |
US5023243A (en) * | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
US4994373A (en) * | 1983-01-27 | 1991-02-19 | Enzo Biochem, Inc. | Method and structures employing chemically-labelled polynucleotide probes |
US5118800A (en) * | 1983-12-20 | 1992-06-02 | California Institute Of Technology | Oligonucleotides possessing a primary amino group in the terminal nucleotide |
US4748111A (en) * | 1984-03-12 | 1988-05-31 | Molecular Diagnostics, Inc. | Nucleic acid-protein conjugate used in immunoassay |
FR2567892B1 (fr) * | 1984-07-19 | 1989-02-17 | Centre Nat Rech Scient | Nouveaux oligonucleotides, leur procede de preparation et leurs applications comme mediateurs dans le developpement des effets des interferons |
US5242794A (en) * | 1984-12-13 | 1993-09-07 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
US5185444A (en) * | 1985-03-15 | 1993-02-09 | Anti-Gene Deveopment Group | Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US5276019A (en) * | 1987-03-25 | 1994-01-04 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors for replication of retroviruses and for the expression of oncogene products |
US4924624A (en) * | 1987-10-22 | 1990-05-15 | Temple University-Of The Commonwealth System Of Higher Education | 2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof |
US5188897A (en) * | 1987-10-22 | 1993-02-23 | Temple University Of The Commonwealth System Of Higher Education | Encapsulated 2',5'-phosphorothioate oligoadenylates |
CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
JPH03503894A (ja) * | 1988-03-25 | 1991-08-29 | ユニバーシィティ オブ バージニア アランミ パテンツ ファウンデイション | オリゴヌクレオチド n‐アルキルホスホラミデート |
US5278302A (en) * | 1988-05-26 | 1994-01-11 | University Patents, Inc. | Polynucleotide phosphorodithioates |
US5216141A (en) * | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
US5198543A (en) | 1989-03-24 | 1993-03-30 | Consejo Superior Investigaciones Cientificas | PHI29 DNA polymerase |
US5001050A (en) | 1989-03-24 | 1991-03-19 | Consejo Superior Investigaciones Cientificas | PHφ29 DNA polymerase |
US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5591722A (en) * | 1989-09-15 | 1997-01-07 | Southern Research Institute | 2'-deoxy-4'-thioribonucleosides and their antiviral activity |
US5399676A (en) * | 1989-10-23 | 1995-03-21 | Gilead Sciences | Oligonucleotides with inverted polarity |
US5516663A (en) * | 1990-01-26 | 1996-05-14 | Abbott Laboratories | Ligase chain reaction with endonuclease IV correction and contamination control |
US5427930A (en) * | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
US5321131A (en) * | 1990-03-08 | 1994-06-14 | Hybridon, Inc. | Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling |
EP0455905B1 (de) * | 1990-05-11 | 1998-06-17 | Microprobe Corporation | Teststreifen zum Eintauchen für Nukleinsäure-Hybridisierungsassays und Verfahren zur kovalenten Immobilisierung von Oligonucleotiden |
WO1992001813A1 (en) | 1990-07-25 | 1992-02-06 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
US5623070A (en) * | 1990-07-27 | 1997-04-22 | Isis Pharmaceuticals, Inc. | Heteroatomic oligonucleoside linkages |
US5618704A (en) * | 1990-07-27 | 1997-04-08 | Isis Pharmacueticals, Inc. | Backbone-modified oligonucleotide analogs and preparation thereof through radical coupling |
US5608046A (en) * | 1990-07-27 | 1997-03-04 | Isis Pharmaceuticals, Inc. | Conjugated 4'-desmethyl nucleoside analog compounds |
US5489677A (en) * | 1990-07-27 | 1996-02-06 | Isis Pharmaceuticals, Inc. | Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms |
US5602240A (en) * | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
BR9106702A (pt) * | 1990-07-27 | 1993-06-08 | Isis Pharmaceuticals Inc | Analogo de oligonucleotideos e processos para modular a producao de uma proteina por um organismo e para tratar um organismo |
US5610289A (en) * | 1990-07-27 | 1997-03-11 | Isis Pharmaceuticals, Inc. | Backbone modified oligonucleotide analogues |
US5177196A (en) * | 1990-08-16 | 1993-01-05 | Microprobe Corporation | Oligo (α-arabinofuranosyl nucleotides) and α-arabinofuranosyl precursors thereof |
US5214134A (en) * | 1990-09-12 | 1993-05-25 | Sterling Winthrop Inc. | Process of linking nucleosides with a siloxane bridge |
JPH06505704A (ja) * | 1990-09-20 | 1994-06-30 | ギリアド サイエンシズ,インコーポレイテッド | 改変ヌクレオシド間結合 |
US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
US5599921A (en) * | 1991-05-08 | 1997-02-04 | Stratagene | Oligonucleotide families useful for producing primers |
US5714331A (en) * | 1991-05-24 | 1998-02-03 | Buchardt, Deceased; Ole | Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility |
US5719262A (en) * | 1993-11-22 | 1998-02-17 | Buchardt, Deceased; Ole | Peptide nucleic acids having amino acid side chains |
DE59208572D1 (de) * | 1991-10-17 | 1997-07-10 | Ciba Geigy Ag | Bicyclische Nukleoside, Oligonukleotide, Verfahren zu deren Herstellung und Zwischenprodukte |
US5594121A (en) * | 1991-11-07 | 1997-01-14 | Gilead Sciences, Inc. | Enhanced triple-helix and double-helix formation with oligomers containing modified purines |
US5412087A (en) * | 1992-04-24 | 1995-05-02 | Affymax Technologies N.V. | Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces |
US5484908A (en) * | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
FR2687679B1 (fr) * | 1992-02-05 | 1994-10-28 | Centre Nat Rech Scient | Oligothionucleotides. |
US5633360A (en) * | 1992-04-14 | 1997-05-27 | Gilead Sciences, Inc. | Oligonucleotide analogs capable of passive cell membrane permeation |
EP0577558A2 (de) * | 1992-07-01 | 1994-01-05 | Ciba-Geigy Ag | Carbocyclische Nukleoside mit bicyclischen Ringen, Oligonukleotide daraus, Verfahren zu deren Herstellung, deren Verwendung und Zwischenproduckte |
US5710028A (en) * | 1992-07-02 | 1998-01-20 | Eyal; Nurit | Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor |
US5614389A (en) * | 1992-08-04 | 1997-03-25 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
WO1994003624A1 (en) * | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
US5733733A (en) * | 1992-08-04 | 1998-03-31 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
US5714320A (en) | 1993-04-15 | 1998-02-03 | University Of Rochester | Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides |
US6096880A (en) | 1993-04-15 | 2000-08-01 | University Of Rochester | Circular DNA vectors for synthesis of RNA and DNA |
US6077668A (en) | 1993-04-15 | 2000-06-20 | University Of Rochester | Highly sensitive multimeric nucleic acid probes |
US5502177A (en) * | 1993-09-17 | 1996-03-26 | Gilead Sciences, Inc. | Pyrimidine derivatives for labeled binding partners |
US5523204A (en) * | 1993-12-10 | 1996-06-04 | Becton Dickinson And Company | Detection of nucleic acids in cells by strand displacement amplification |
US5519134A (en) * | 1994-01-11 | 1996-05-21 | Isis Pharmaceuticals, Inc. | Pyrrolidine-containing monomers and oligomers |
SE9400522D0 (sv) | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
CA2185239C (en) * | 1994-03-16 | 2002-12-17 | Nanibhushan Dattagupta | Isothermal strand displacement nucleic acid amplification |
US5596091A (en) * | 1994-03-18 | 1997-01-21 | The Regents Of The University Of California | Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides |
US5627053A (en) * | 1994-03-29 | 1997-05-06 | Ribozyme Pharmaceuticals, Inc. | 2'deoxy-2'-alkylnucleotide containing nucleic acid |
US5625050A (en) * | 1994-03-31 | 1997-04-29 | Amgen Inc. | Modified oligonucleotides and intermediates useful in nucleic acid therapeutics |
US5525711A (en) * | 1994-05-18 | 1996-06-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Pteridine nucleotide analogs as fluorescent DNA probes |
US5942391A (en) | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
US5876924A (en) | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
US5597909A (en) * | 1994-08-25 | 1997-01-28 | Chiron Corporation | Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use |
US5516134A (en) * | 1994-09-20 | 1996-05-14 | Perfect Season, Inc. | Seat for a wheeled vehicle |
FR2726277B1 (fr) * | 1994-10-28 | 1996-12-27 | Bio Merieux | Oligonucleotide utilisable comme amorce dans une methode d'amplification basee sur une replication avec deplacement de brin |
US5766891A (en) * | 1994-12-19 | 1998-06-16 | Sloan-Kettering Institute For Cancer Research | Method for molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase |
US5629179A (en) * | 1995-03-17 | 1997-05-13 | Novagen, Inc. | Method and kit for making CDNA library |
EP1505159B1 (de) * | 1995-03-17 | 2008-05-28 | John Wayne Cancer Institute | Nachweis von Brustmetastasen unter Verwendung eines Mehrfachmarker-Tests |
US5728526A (en) * | 1995-06-07 | 1998-03-17 | Oncor, Inc. | Method for analyzing a nucleotide sequence |
AT402203B (de) * | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
US5854033A (en) * | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
DK0862656T3 (da) * | 1995-11-21 | 2001-04-09 | Univ Yale | Unimolekylær segmentamplifikation og -detektering |
US5877637A (en) * | 1996-02-05 | 1999-03-02 | Trofimenkoff; Frederick N. | Resistance bridge and its use in conversion systems |
GB9609213D0 (en) | 1996-05-02 | 1996-07-03 | Tepnel Medical Ltd | Amplification of nucleic acids |
US5614390A (en) * | 1996-06-14 | 1997-03-25 | Becton, Dickinson And Company | Species-specific detection of Mycobacterium kansasii |
US5866336A (en) * | 1996-07-16 | 1999-02-02 | Oncor, Inc. | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
US6017703A (en) * | 1997-03-06 | 2000-01-25 | Bard Diagnostic Sciences, Inc. | Methods and compositions for screening for or modulating a tumor associated antigen |
US6124120A (en) * | 1997-10-08 | 2000-09-26 | Yale University | Multiple displacement amplification |
US6054274A (en) * | 1997-11-12 | 2000-04-25 | Hewlett-Packard Company | Method of amplifying the signal of target nucleic acid sequence analyte |
US6203984B1 (en) * | 1998-07-02 | 2001-03-20 | Pacron, Inc. | Proportional amplification of mRNA from a linear template in vitro |
US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
US6235502B1 (en) * | 1998-09-18 | 2001-05-22 | Molecular Staging Inc. | Methods for selectively isolating DNA using rolling circle amplification |
US6703228B1 (en) * | 1998-09-25 | 2004-03-09 | Massachusetts Institute Of Technology | Methods and products related to genotyping and DNA analysis |
US6830884B1 (en) * | 1998-12-15 | 2004-12-14 | Molecular Staging Inc. | Method of amplification |
US6355431B1 (en) * | 1999-04-20 | 2002-03-12 | Illumina, Inc. | Detection of nucleic acid amplification reactions using bead arrays |
US6277607B1 (en) * | 1999-05-24 | 2001-08-21 | Sanjay Tyagi | High specificity primers, amplification methods and kits |
JP2003532380A (ja) * | 1999-12-02 | 2003-11-05 | モレキュラー ステージング,インコーポレイテッド | 線状自己アニーリングセグメントからの一本鎖環状dnaの産出 |
US6221603B1 (en) * | 2000-02-04 | 2001-04-24 | Molecular Dynamics, Inc. | Rolling circle amplification assay for nucleic acid analysis |
CA2405687A1 (en) * | 2000-04-05 | 2001-10-18 | Molecular Staging, Inc. | Process for allele discrimation utilizing primer extension |
US6368801B1 (en) * | 2000-04-12 | 2002-04-09 | Molecular Staging, Inc. | Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase |
US6531283B1 (en) * | 2000-06-20 | 2003-03-11 | Molecular Staging, Inc. | Protein expression profiling |
JP2004502431A (ja) * | 2000-06-30 | 2004-01-29 | モレキュラー ステージング,インコーポレイテッド | ロリポッププローブを用いたシグナル増幅 |
US6713257B2 (en) * | 2000-08-25 | 2004-03-30 | Rosetta Inpharmatics Llc | Gene discovery using microarrays |
WO2002061133A2 (en) * | 2000-11-09 | 2002-08-08 | Yale University | Nucleic acid detection using structured probes |
US6635425B2 (en) * | 2001-01-05 | 2003-10-21 | Molecular Staging, Inc. | 5′-thio phosphate directed ligation of oligonucleotides and use in detection of single nucleotide polymorphisms |
US6573051B2 (en) * | 2001-03-09 | 2003-06-03 | Molecular Staging, Inc. | Open circle probes with intramolecular stem structures |
WO2002103058A2 (en) * | 2001-06-19 | 2002-12-27 | Molecular Staging, Inc. | Process for enhanced molecular target detection using layered rolling circle amplification |
US20040091857A1 (en) * | 2001-07-20 | 2004-05-13 | Nallur Girish N. | Gene expression profiling |
US6703885B1 (en) * | 2002-09-18 | 2004-03-09 | Richtek Technology Corp. | Trimmer method and device for circuits |
-
2000
- 2000-06-28 US US09/605,192 patent/US6323009B1/en not_active Expired - Lifetime
-
2001
- 2001-06-27 IL IL15309701A patent/IL153097A0/xx unknown
- 2001-06-27 WO PCT/US2001/020217 patent/WO2002000934A2/en active IP Right Grant
- 2001-06-27 EP EP01946712A patent/EP1315833B1/de not_active Expired - Lifetime
- 2001-06-27 JP JP2002506247A patent/JP4718756B2/ja not_active Expired - Lifetime
- 2001-06-27 CA CA002410951A patent/CA2410951A1/en not_active Abandoned
- 2001-06-27 AU AU6872501A patent/AU6872501A/xx active Pending
- 2001-06-27 AT AT01946712T patent/ATE343003T1/de not_active IP Right Cessation
- 2001-06-27 AU AU2001268725A patent/AU2001268725B2/en not_active Ceased
- 2001-06-27 DE DE60123980T patent/DE60123980T2/de not_active Expired - Lifetime
- 2001-07-31 US US09/920,571 patent/US20030207267A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030207267A1 (en) | 2003-11-06 |
AU6872501A (en) | 2002-01-08 |
CA2410951A1 (en) | 2002-01-03 |
DE60123980D1 (de) | 2006-11-30 |
EP1315833A2 (de) | 2003-06-04 |
JP2004512823A (ja) | 2004-04-30 |
DE60123980T2 (de) | 2007-06-21 |
WO2002000934A3 (en) | 2003-04-03 |
JP4718756B2 (ja) | 2011-07-06 |
AU2001268725B2 (en) | 2006-08-03 |
EP1315833B1 (de) | 2006-10-18 |
WO2002000934A2 (en) | 2002-01-03 |
ATE343003T1 (de) | 2006-11-15 |
US6323009B1 (en) | 2001-11-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL153097A0 (en) | A process for selectively amplifying nucleic acid sequences | |
WO2002052031A3 (en) | Nucleic acid amplification | |
NO20021223L (no) | Fremgangsmater og sammensetninger for lineaer, isoterm amplifisering av polynukleotidsekvenser | |
AU6846698A (en) | Method of nucleic acid amplification | |
WO1997018334A3 (en) | Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits | |
WO1997004126B1 (fr) | Procede d'amplification de sequences d'acide nucleique par deplacement, a l'aide d'amorces chimeres | |
EP1026262A3 (de) | Oligonukleotidprimer zur effizienten Detektion von Hepatitis C Virus (HCV) sowie Verwendungsverfahren | |
WO2003004614A3 (en) | Identification and use of conserved noncoding sequences | |
WO2001012853A8 (en) | Method for identification of the indicators of contamination in samples | |
WO2003087390A3 (en) | Methods for detecting abnormally methylated nucleic acid in heterogeneous biological samples | |
WO2001077335A3 (fr) | Genome de listeria monocytogenes, polypeptides et utilisations | |
DK1815013T3 (da) | Sammensætning til at amplificere nucleinsyrer | |
IL132292A0 (en) | Process for the preparation of pantothenic acid by amplification of nucleotide sequences which code for ketopantoate reductase | |
EP1212449A4 (de) | Verfahren zur amplifikation von signal-flankierenden sequenzen aus unbekannten, genomischen daten | |
NZ505062A (en) | Detection of fungal pathogens in grape plants using oligonucleotide primers | |
EP1422298A3 (de) | HIV-1 Detektion mittels Nukleinsäureamplifizierung | |
WO2003040397A3 (en) | Asymmetric pcr with nuclease-free polymerase or nuclease-resistant molecular beacons | |
IL149791A0 (en) | Oligonucleotides and assemblies thereof useful in the detection of the presence or absence of target nucleic acid sequences in a sample | |
WO1996015264A3 (en) | Method for identifying nucleic acid sequences from different biological sources through amplification of the same | |
WO2001044510A3 (en) | Nucleic acid amplification and detection of mycobacterium species | |
WO2004097003A3 (en) | Multiply-primed amplification of nucleic acid sequences | |
AU2003211947A1 (en) | PRIMERS FOR NUCLEIC ACID AMPLIFICATION IN DETECTING HOUSEKEEPING GENE mRNA AND TEST METHOD USING THESE PRIMERS | |
WO1990009457A3 (en) | Oligonucleotide primer pairs for sequence independent gene amplification and methods which employ them | |
BRPI0001536B8 (de) | ||
ATE312204T1 (de) | Methoden und zusammensetzungen zur detektion von spezies des mycobacterium avium-komplexes |