IL152770A0 - Gabapentin analogues for sleep disorders - Google Patents

Gabapentin analogues for sleep disorders

Info

Publication number
IL152770A0
IL152770A0 IL15277001A IL15277001A IL152770A0 IL 152770 A0 IL152770 A0 IL 152770A0 IL 15277001 A IL15277001 A IL 15277001A IL 15277001 A IL15277001 A IL 15277001A IL 152770 A0 IL152770 A0 IL 152770A0
Authority
IL
Israel
Prior art keywords
sleep disorders
gabapentin analogues
gabapentin
analogues
compounds
Prior art date
Application number
IL15277001A
Other languages
English (en)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL152770A0 publication Critical patent/IL152770A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15277001A 2000-06-26 2001-05-18 Gabapentin analogues for sleep disorders IL152770A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21417100P 2000-06-26 2000-06-26
PCT/US2001/016343 WO2002000209A2 (en) 2000-06-26 2001-05-18 Gabapentin analogues for sleep disorders

Publications (1)

Publication Number Publication Date
IL152770A0 true IL152770A0 (en) 2003-06-24

Family

ID=22798045

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15277001A IL152770A0 (en) 2000-06-26 2001-05-18 Gabapentin analogues for sleep disorders
IL152770A IL152770A (en) 2000-06-26 2002-11-11 Use of Gabapentin analogues for the preparation of preparations for the treatment of sleep disorders

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL152770A IL152770A (en) 2000-06-26 2002-11-11 Use of Gabapentin analogues for the preparation of preparations for the treatment of sleep disorders

Country Status (24)

Country Link
US (1) US7141606B2 (de)
EP (1) EP1296671B1 (de)
JP (1) JP3909842B2 (de)
KR (1) KR100785182B1 (de)
CN (1) CN1279900C (de)
AT (1) ATE390133T1 (de)
AU (2) AU2001264736B2 (de)
BR (1) BR0111913A (de)
CA (1) CA2414008C (de)
CZ (1) CZ20024110A3 (de)
DE (1) DE60133389T2 (de)
DK (1) DK1296671T3 (de)
ES (1) ES2300332T3 (de)
HK (1) HK1056681A1 (de)
HU (1) HUP0300833A3 (de)
IL (2) IL152770A0 (de)
MX (1) MXPA02010668A (de)
NZ (1) NZ522480A (de)
PL (1) PL359872A1 (de)
PT (1) PT1296671E (de)
SK (1) SK17922002A3 (de)
TW (1) TWI298020B (de)
WO (1) WO2002000209A2 (de)
ZA (1) ZA200209418B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK12822003A3 (sk) 2001-04-19 2004-04-06 Warner - Lambert Company Llc Fúzne bicyklické alebo tricyklické aminokyseliny
ES2380287T3 (es) 2001-06-11 2012-05-10 Xenoport, Inc. Profármacos de análogos de GABA, composiciones y sus usos
AU2002345638A1 (en) 2001-06-11 2002-12-23 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
EP1485082A4 (de) 2002-02-19 2009-12-30 Xenoport Inc Syntheseverfahren für prodrugs von 1-acyl-alkyl derivaten und ihre zusammensetzungen
WO2003080588A1 (en) 2002-03-20 2003-10-02 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
AU2003243180A1 (en) 2002-05-17 2003-12-12 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
AU2003297927A1 (en) 2002-12-11 2004-06-30 Xenoport, Inc. Prodrugs of fused gaba analogs, pharmaceutical compositions and uses thereof
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
JP2006511605A (ja) * 2002-12-13 2006-04-06 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 線維筋痛及び他の関連障害のためのガバペンチン類縁体
EP1622603A4 (de) * 2003-03-25 2010-03-24 Kiel Lab Inc Phenolsäuresalze von gabapentin in festen dosierformen und anwendungsverfahren
US7700652B2 (en) 2003-09-11 2010-04-20 Xenoport, Inc. Treating urinary incontinence using prodrugs of GABA analogs
SG146643A1 (en) 2003-09-17 2008-10-30 Xenoport Inc Treating or preventing restless legs syndrome using prodrugs of gaba analogs
KR101096480B1 (ko) 2003-10-14 2011-12-20 제노포트 인코포레이티드 감마-아미노부티르산 유사체의 결정질 형태
JP4613031B2 (ja) * 2004-05-06 2011-01-12 エスエス製薬株式会社 催眠剤組成物
JP2005325070A (ja) * 2004-05-14 2005-11-24 Ss Pharmaceut Co Ltd 睡眠改善剤
MX2007005306A (es) 2004-11-04 2007-06-11 Xenoport Inc Formas de dosis oral de liberacion sostenida de la prodroga gabapentina.
JP2009505947A (ja) 2005-06-23 2009-02-12 エモリー・ユニバーシティ 画像化剤
KR20070070307A (ko) * 2005-08-24 2007-07-04 에스에스 세야쿠 가부시키 가이샤 수면 개선 의약 조성물
EP1993529A1 (de) * 2006-03-06 2008-11-26 Pfizer Products Inc. Alpha-2-delta-liganden für nicht-restorativen schlaf
EP2250148B1 (de) 2008-01-25 2016-08-17 XenoPort, Inc. Kristalline form von kalziumsalzen von (3s)-aminomethyl-5-methylhexansäuren und anwendungsverfahren
JP5291123B2 (ja) 2008-01-25 2013-09-18 ゼノポート，インコーポレイティド （３ｓ）−アミノメチル−５−ヘキサン酸プロドラッグの結晶形態及びその使用
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
JP2012505238A (ja) 2008-10-08 2012-03-01 カイフィア ファーマシューティカルズ， インコーポレイテッド Ｇａｂａコンジュゲートおよびそれらの使用方法
CA2783699C (en) 2009-12-08 2019-01-15 Case Western Reserve University Primary amine compounds for treating ocular disorders
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
EP2948139B1 (de) 2013-01-28 2019-06-12 Lopez, Hector, L. Verfahren zur verbesserung der verträglichkeit, pharmakodynamik und wirksamkeit von b-alanin und verwendung davon
KR20230047198A (ko) * 2016-05-26 2023-04-06 가부시키가이샤 아미노 압 수면 개선제
KR20210013081A (ko) 2018-05-14 2021-02-03 엑스진 파마슈티컬 인크. 나프록센 및 프레가발린의 1-(아실옥시)-알킬 카르바메이트 약물 복합체의 결정형

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US5084479A (en) * 1990-01-02 1992-01-28 Warner-Lambert Company Novel methods for treating neurodegenerative diseases
US6197819B1 (en) * 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
US5510381A (en) * 1995-05-15 1996-04-23 Warner-Lambert Company Method of treatment of mania and bipolar disorder
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
EA001214B1 (ru) * 1996-03-14 2000-12-25 Варнер-Ламберт Компани Новые мостиковые циклические аминокислоты как фармацевтически применимые вещества
US6372792B1 (en) * 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
CN1138755C (zh) 1997-10-27 2004-02-18 沃尼尔·朗伯公司 作为药物的环状氨基酸及其衍生物
US6306910B1 (en) 1998-07-09 2001-10-23 Warner-Lambert Company Use of Gaba-analogues for treating insomnia
PT1187832E (pt) * 1999-06-02 2003-03-31 Warner Lambert Co Amino heterociclos uteis como agentes farmaceuticos
HN2000000224A (es) * 1999-10-20 2001-04-11 Warner Lambert Co Aminoacidos biciclicos como agentes farmaceuticos
WO2001042190A1 (en) 1999-12-08 2001-06-14 Warner-Lambert Company Method for the stereoselective synthesis of cyclic amino acids
GB9930083D0 (en) * 1999-12-20 2000-02-09 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
CA2414008A1 (en) 2002-01-03
MXPA02010668A (es) 2003-03-10
WO2002000209A2 (en) 2002-01-03
CA2414008C (en) 2011-04-26
EP1296671A2 (de) 2003-04-02
CN1279900C (zh) 2006-10-18
IL152770A (en) 2009-12-24
TWI298020B (en) 2008-06-21
KR20030019455A (ko) 2003-03-06
US20030212133A1 (en) 2003-11-13
BR0111913A (pt) 2004-01-06
JP2004501189A (ja) 2004-01-15
AU6473601A (en) 2002-01-08
ATE390133T1 (de) 2008-04-15
SK17922002A3 (sk) 2003-11-04
NZ522480A (en) 2005-06-24
ZA200209418B (en) 2005-03-10
CN1436075A (zh) 2003-08-13
EP1296671B1 (de) 2008-03-26
HUP0300833A3 (en) 2009-08-28
DE60133389D1 (de) 2008-05-08
ES2300332T3 (es) 2008-06-16
DK1296671T3 (da) 2008-06-16
CZ20024110A3 (cs) 2003-10-15
US7141606B2 (en) 2006-11-28
JP3909842B2 (ja) 2007-04-25
KR100785182B1 (ko) 2007-12-11
PL359872A1 (en) 2004-09-06
AU2001264736B2 (en) 2006-04-27
PT1296671E (pt) 2008-05-09
HUP0300833A2 (hu) 2003-08-28
HK1056681A1 (en) 2004-02-27
WO2002000209A3 (en) 2003-01-16
DE60133389T2 (de) 2008-06-26

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