JP2000189171A
(ja)
|
1998-12-25 |
2000-07-11 |
Banyu Pharmaceut Co Ltd |
新規なグアノシン三リン酸(gtp)結合タンパク質共役型のレセプタ―タンパク質
|
US20030143668A1
(en)
*
|
2001-06-18 |
2003-07-31 |
National Institute Of Advanced Industrial |
Guanosine triphosphate-binding protein coupled receptors
|
EP1448600A4
(de)
*
|
2001-09-07 |
2004-12-22 |
Bristol Myers Squibb Co |
Für einen neuen menschlichen g-protein-gekoppelten rezeptor hgprbmy39 codierendes polynukleotid
|
JP2005522999A
(ja)
*
|
2002-01-31 |
2005-08-04 |
ミレニアム・ファーマシューティカルズ・インコーポレイテッド |
癌を処置するための方法および組成物
|
AU2003211501A1
(en)
*
|
2002-02-08 |
2003-09-02 |
Nakoshi, Hideo |
Peptides
|
EP1505074A4
(de)
|
2002-04-24 |
2005-12-21 |
Banyu Pharma Co Ltd |
Konstitutiv aktive mutanten eines histamin h3 rezeptors und deren verwendungen
|
AU2003229736A1
(en)
*
|
2002-05-02 |
2003-11-17 |
Bayer Aktiengesellschaft |
Diagnostics and therapeutics for diseases associated with neurotensin receptor 1 (nt1)
|
AU2003240468A1
(en)
*
|
2002-05-02 |
2003-11-17 |
Bayer Aktiengesellschaft |
Diagnostics and therapeutics for diseases associated with neurotensin receptor 2 (nt2)
|
EP1365244A1
(de)
*
|
2002-05-23 |
2003-11-26 |
Bayer Ag |
Diagnose und Therapie von Arginin Vasopressin Rezeptor 2 assoziierten Erkrankungen
|
EP1365247A1
(de)
*
|
2002-05-23 |
2003-11-26 |
Bayer Ag |
Diagnose und Therapie von Arginin Vasopressin Rezeptor 3 assoziierten Erkrankungen
|
EP1364968A1
(de)
*
|
2002-05-23 |
2003-11-26 |
Bayer Aktiengesellschaft |
Diagnostika und Therapeutika für Krankheiten, die mit Arginin-Vasopressin-Rezeptor 1 (AVPR1) assoziiert sind
|
SE0202240D0
(sv)
*
|
2002-07-17 |
2002-07-17 |
Astrazeneca Ab |
Genes
|
WO2004071396A2
(en)
*
|
2003-02-17 |
2004-08-26 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with parathyroid hormone receptor 2 (pthr2)
|
WO2004073587A2
(en)
*
|
2003-02-19 |
2004-09-02 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with parathyroid hormone receptor 1 (pthr1)
|
US20070276024A1
(en)
*
|
2003-10-09 |
2007-11-29 |
Inverseon , Inc. |
Methods for Treating Diseases and Conditions with Inverse Agonists and for Screening for Agents Acting as Inverse Agonists
|
WO2005034871A2
(en)
*
|
2003-10-09 |
2005-04-21 |
Inverseon, Inc. |
Methods for treating diseases and conditions with inverse agonists
|
KR101438983B1
(ko)
|
2003-11-06 |
2014-09-05 |
시애틀 지네틱스, 인크. |
리간드에 접합될 수 있는 모노메틸발린 화합물
|
AU2003300239A1
(en)
*
|
2003-12-29 |
2005-07-21 |
Galapagos Genomics N.V. |
Modulators of bone homeostasis identified in a high-throughput screen
|
WO2005114206A2
(en)
*
|
2004-05-13 |
2005-12-01 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with serotonin 5-ht5a receptor (5ht5a)
|
AU2005249490B2
(en)
|
2004-06-01 |
2010-07-29 |
Genentech, Inc. |
Antibody drug conjugates and methods
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
PL1791565T3
(pl)
|
2004-09-23 |
2016-10-31 |
|
Modyfikowane cysteiną przeciwciała i koniugaty
|
US7528175B2
(en)
*
|
2004-10-08 |
2009-05-05 |
Inverseon, Inc. |
Method of treating airway diseases with beta-adrenergic inverse agonists
|
US20070218456A1
(en)
*
|
2006-02-08 |
2007-09-20 |
Invitrogen Corporation |
Cellular assays for signaling receptors
|
WO2007113388A2
(en)
*
|
2006-03-31 |
2007-10-11 |
Licentia Oy |
Method and microarray for detecting herpesviruses
|
US8354273B2
(en)
*
|
2007-10-17 |
2013-01-15 |
Universidad De Cordoba |
Isoforms of human somatostatin receptor type 5
|
WO2009059021A2
(en)
*
|
2007-10-30 |
2009-05-07 |
Intermune, Inc. |
Hcv genotyping and phenotyping
|
GB0724860D0
(en)
*
|
2007-12-20 |
2008-01-30 |
Heptares Therapeutics Ltd |
Screening
|
US8470980B2
(en)
|
2009-09-09 |
2013-06-25 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
WO2011130598A1
(en)
|
2010-04-15 |
2011-10-20 |
Spirogen Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
MX336540B
(es)
|
2010-06-08 |
2016-01-22 |
Genentech Inc |
Conjugados y anticuerpos manipulados geneticamente con cisteina.
|
CA2816426A1
(en)
|
2010-11-17 |
2012-06-07 |
Genentech, Inc. |
Alaninyl maytansinol antibody conjugates
|
CA2833212C
(en)
|
2011-05-12 |
2020-06-09 |
Genentech, Inc. |
Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides
|
CN102276731B
(zh)
*
|
2011-08-16 |
2013-03-27 |
北京大学 |
抑制可卡因诱发的高运动活性的多肽及其应用
|
US11135303B2
(en)
|
2011-10-14 |
2021-10-05 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
EP2839860B1
(de)
|
2012-10-12 |
2019-05-01 |
MedImmune Limited |
Pyrrolobenzodiazepine und Konjugate davon
|
EP2906297B1
(de)
|
2012-10-12 |
2017-12-06 |
ADC Therapeutics SA |
Pyrrolobenzodiazepin-antikörper-konjugate
|
CA2887895C
(en)
|
2012-10-12 |
2019-10-29 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine-anti-cd19 antibody conjugates
|
WO2014057114A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
JP6392765B2
(ja)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa |
ピロロベンゾジアゼピン−抗体結合体
|
CN105102003B
(zh)
|
2012-10-12 |
2019-03-05 |
Adc疗法责任有限公司 |
吡咯并苯并二氮杂卓-抗psma抗体结合物
|
MX364328B
(es)
|
2012-10-12 |
2019-04-23 |
Medimmune Ltd |
Conjugados del anticuerpo pirrolobenzodiazepina.
|
WO2014096365A1
(en)
|
2012-12-21 |
2014-06-26 |
Spirogen Sàrl |
Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
|
AU2013366493B2
(en)
|
2012-12-21 |
2017-08-24 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
JP6444902B2
(ja)
|
2013-03-13 |
2018-12-26 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン及びその結合体
|
BR112015021965B1
(pt)
|
2013-03-13 |
2022-05-03 |
Medimmune Limited |
Conjugados e compostos de pirrolobenzodiazepinas, composição farmacêutica, uso dos mesmos para o tratamento de uma doença proliferativa e método de síntese dos ditos compostos
|
KR102057755B1
(ko)
|
2013-03-13 |
2019-12-19 |
메디뮨 리미티드 |
피롤로벤조디아제핀 및 그의 컨쥬게이트
|
EA201690195A1
(ru)
|
2013-08-12 |
2016-05-31 |
Дженентек, Инк. |
Конъюгатные соединения антитело-лекарство на основе димера 1-(хлорметил)-2,3-дигидро-1h-бензо[e]индола и способы применения и лечения
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3054985B1
(de)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
EP3054983B1
(de)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
RU2689388C1
(ru)
|
2013-12-16 |
2019-05-28 |
Дженентек, Инк. |
Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами
|
CA2933557A1
(en)
|
2013-12-16 |
2015-06-25 |
Genentech, Inc. |
Peptidomimetic compounds and antibody-drug conjugates thereof
|
CN105828840B
(zh)
|
2013-12-16 |
2020-08-04 |
基因泰克公司 |
1-(氯甲基)-2,3-二氢-1H-苯并[e]吲哚二聚体抗体-药物缀合物化合物及使用和治疗方法
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3191521A2
(de)
|
2014-09-12 |
2017-07-19 |
F. Hoffmann-La Roche AG |
Cystein-manipulierte antikörper und konjugate
|
CN106714844B
(zh)
|
2014-09-12 |
2022-08-05 |
基因泰克公司 |
蒽环类二硫化物中间体、抗体-药物缀合物和方法
|
PE20170905A1
(es)
|
2014-09-17 |
2017-07-12 |
Genentech Inc |
Pirrolobenzodiazepinas y conjugados de anticuerpo-disulfuro de las mismas
|
CA2968447A1
(en)
|
2014-11-25 |
2016-06-02 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates and their use to treat neoplasms
|
CN107206101B
(zh)
|
2014-12-03 |
2021-06-25 |
基因泰克公司 |
季铵化合物及其抗体-药物缀合物
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
EP3416640A1
(de)
|
2016-02-16 |
2018-12-26 |
Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts |
Modulatoren der tumorimmunresistenz zur behandlung von krebs
|
US20190054110A1
(en)
|
2016-02-16 |
2019-02-21 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Modulators of ccr9 for treating tumor resistance to immune responses
|
JP6943872B2
(ja)
|
2016-03-25 |
2021-10-06 |
ジェネンテック, インコーポレイテッド |
多重全抗体及び抗体複合体化薬物定量化アッセイ
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
PL3458101T3
(pl)
|
2016-05-20 |
2021-05-31 |
F. Hoffmann-La Roche Ag |
Koniugaty PROTAC-przeciwciało i sposoby ich stosowania
|
CN109313200B
(zh)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
用于表征位点特异性抗体-药物缀合物的生物分析性方法
|
JP7043425B2
(ja)
|
2016-06-06 |
2022-03-29 |
ジェネンテック, インコーポレイテッド |
シルベストロール抗体-薬物コンジュゲート及び使用方法
|
JP7093767B2
(ja)
|
2016-08-11 |
2022-06-30 |
ジェネンテック, インコーポレイテッド |
ピロロベンゾジアゼピンプロドラッグ及びその抗体コンジュゲート
|
CN110139674B
(zh)
|
2016-10-05 |
2023-05-16 |
豪夫迈·罗氏有限公司 |
制备抗体药物缀合物的方法
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
JP6671555B2
(ja)
|
2017-02-08 |
2020-03-25 |
アーデーセー セラピューティクス ソシエテ アノニム |
ピロロベンゾジアゼピン抗体複合体
|
JP2020517609A
(ja)
|
2017-04-18 |
2020-06-18 |
メディミューン リミテッド |
ピロロベンゾジアゼピン複合体
|
CA3057748A1
(en)
|
2017-04-20 |
2018-10-25 |
Adc Therapeutics Sa |
Combination therapy with an anti-axl antibody-drug conjugate
|
WO2018229222A1
(en)
|
2017-06-14 |
2018-12-20 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-cd19 adc
|
WO2019034764A1
(en)
|
2017-08-18 |
2019-02-21 |
Medimmune Limited |
CONJUGATES OF PYRROLOBENZODIAZEPINE
|
JP2020534300A
(ja)
|
2017-09-20 |
2020-11-26 |
ピーエイチ・ファーマ・カンパニー・リミテッドPh Pharma Co., Ltd. |
タイランスタチン類似体
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
WO2020086858A1
(en)
|
2018-10-24 |
2020-04-30 |
Genentech, Inc. |
Conjugated chemical inducers of degradation and methods of use
|
WO2020123275A1
(en)
|
2018-12-10 |
2020-06-18 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
WO2021011799A1
(en)
*
|
2019-07-16 |
2021-01-21 |
Fundación Ciencia Para La Vida (Fcv) |
Inflammatory bowel diseases therapy involving disrupting ccr9:drd5 heteromer assembly
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|