IL149100A0 - Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase - Google Patents

Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase

Info

Publication number
IL149100A0
IL149100A0 IL14910000A IL14910000A IL149100A0 IL 149100 A0 IL149100 A0 IL 149100A0 IL 14910000 A IL14910000 A IL 14910000A IL 14910000 A IL14910000 A IL 14910000A IL 149100 A0 IL149100 A0 IL 149100A0
Authority
IL
Israel
Prior art keywords
heteroalkylamino
inhibitors
protein kinase
substituted bicyclic
nitrogen heterocycles
Prior art date
Application number
IL14910000A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL149100A0 publication Critical patent/IL149100A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
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IL14910000A 1999-10-21 2000-10-13 Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase IL149100A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16080399P 1999-10-21 1999-10-21
US21374300P 2000-06-22 2000-06-22
PCT/EP2000/010088 WO2001029042A1 (en) 1999-10-21 2000-10-13 Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase

Publications (1)

Publication Number Publication Date
IL149100A0 true IL149100A0 (en) 2002-11-10

Family

ID=26857240

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14910000A IL149100A0 (en) 1999-10-21 2000-10-13 Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase

Country Status (27)

Country Link
US (1) US6451804B1 (ko)
EP (1) EP1228070B1 (ko)
JP (1) JP3961830B2 (ko)
KR (1) KR100523120B1 (ko)
CN (1) CN1171889C (ko)
AR (1) AR026084A1 (ko)
AT (1) ATE353329T1 (ko)
AU (1) AU776250B2 (ko)
BR (1) BR0015243A (ko)
CA (1) CA2388142C (ko)
CZ (1) CZ20021744A3 (ko)
DE (1) DE60033307T2 (ko)
ES (1) ES2280247T3 (ko)
HK (1) HK1051039A1 (ko)
HR (1) HRP20020328A2 (ko)
HU (1) HUP0203564A3 (ko)
IL (1) IL149100A0 (ko)
MA (1) MA26837A1 (ko)
MX (1) MXPA02003950A (ko)
NO (1) NO20021781L (ko)
NZ (1) NZ518119A (ko)
PE (1) PE20010758A1 (ko)
PL (1) PL357502A1 (ko)
RU (1) RU2265606C2 (ko)
TR (1) TR200201057T2 (ko)
WO (1) WO2001029042A1 (ko)
YU (1) YU29102A (ko)

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AU2003225072A1 (en) * 2002-04-19 2003-11-03 Smithkline Beecham Corporation Novel compounds
CA2492033A1 (en) 2002-07-09 2004-01-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
US7196090B2 (en) 2002-07-25 2007-03-27 Warner-Lambert Company Kinase inhibitors
EP1539755B1 (en) * 2002-08-06 2007-09-26 F. Hoffmann-La Roche Ag 6-alkoxy-pyrido-pyrimidines as p-38 map kinase inhibitors
US7084270B2 (en) * 2002-08-14 2006-08-01 Hoffman-La Roche Inc. Pyrimido compounds having antiproliferative activity
TW200413381A (en) 2002-11-04 2004-08-01 Hoffmann La Roche Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
US7129351B2 (en) 2002-11-04 2006-10-31 Hoffmann-La Roche Inc. Pyrimido compounds having antiproliferative activity
JP2006514624A (ja) * 2002-11-18 2006-05-11 エフ．ホフマン−ラ　ロシュ　アーゲー ジアジノピリミジン類
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US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
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WO2006038112A1 (en) * 2004-10-01 2006-04-13 Warner-Lambert Company Llc Use of kinase inhibitors to promote neochondrogenesis
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ES2329639B1 (es) 2007-04-26 2010-09-23 Laboratorios Almirall S.A. Nuevos derivados de 4,8-difenilpoliazanaftaleno.
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
GB2452696B (en) * 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
EP2108641A1 (en) * 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
HUE032947T2 (en) 2009-09-30 2017-11-28 Toray Industries 2,3-dihydro-1H-inden-2-yl urea and its pharmaceutical use
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
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