IL146750A0 - Ethanesulfonyl-piperidine derivatives - Google Patents

Ethanesulfonyl-piperidine derivatives

Info

Publication number
IL146750A0
IL146750A0 IL14675000A IL14675000A IL146750A0 IL 146750 A0 IL146750 A0 IL 146750A0 IL 14675000 A IL14675000 A IL 14675000A IL 14675000 A IL14675000 A IL 14675000A IL 146750 A0 IL146750 A0 IL 146750A0
Authority
IL
Israel
Prior art keywords
ethanesulfonyl
piperidine derivatives
piperidine
derivatives
Prior art date
Application number
IL14675000A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL146750A0 publication Critical patent/IL146750A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14675000A 1999-06-08 2000-05-31 Ethanesulfonyl-piperidine derivatives IL146750A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99111126 1999-06-08
PCT/EP2000/004953 WO2000075109A1 (en) 1999-06-08 2000-05-31 Ethanesulfonyl-piperidine derivatives

Publications (1)

Publication Number Publication Date
IL146750A0 true IL146750A0 (en) 2002-07-25

Family

ID=8238316

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14675000A IL146750A0 (en) 1999-06-08 2000-05-31 Ethanesulfonyl-piperidine derivatives
IL146750A IL146750A (en) 1999-06-08 2001-11-26 Derivatives of ethensulfonyl-piperidine

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL146750A IL146750A (en) 1999-06-08 2001-11-26 Derivatives of ethensulfonyl-piperidine

Country Status (38)

Country Link
US (1) US6310213B1 (de)
EP (1) EP1189886B1 (de)
JP (1) JP3645856B2 (de)
KR (1) KR100571162B1 (de)
CN (1) CN1142141C (de)
AR (1) AR024282A1 (de)
AT (1) ATE315025T1 (de)
AU (1) AU770787B2 (de)
BR (1) BR0011419A (de)
CA (1) CA2376091C (de)
CO (1) CO5160328A1 (de)
CZ (1) CZ299483B6 (de)
DE (1) DE60025348T2 (de)
DK (1) DK1189886T3 (de)
EG (1) EG26101A (de)
ES (1) ES2254183T3 (de)
GC (1) GC0000256A (de)
GT (1) GT200000089A (de)
HK (1) HK1046412B (de)
HR (1) HRP20010885B1 (de)
HU (1) HU228591B1 (de)
IL (2) IL146750A0 (de)
JO (1) JO2260B1 (de)
MA (1) MA26797A1 (de)
MX (1) MXPA01012585A (de)
MY (1) MY128818A (de)
NO (1) NO320613B1 (de)
PA (1) PA8496601A1 (de)
PE (1) PE20010218A1 (de)
PL (1) PL196053B1 (de)
RS (1) RS50033B (de)
RU (1) RU2242464C2 (de)
SI (1) SI1189886T1 (de)
TN (1) TNSN00125A1 (de)
TR (1) TR200103532T2 (de)
TW (1) TWI254043B (de)
WO (1) WO2000075109A1 (de)
ZA (1) ZA200109706B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60104923T2 (de) 2000-03-22 2005-08-25 F. Hoffmann-La Roche Ag Piperidin- und Pirazinverbindungen zur Verwendung in der Behandlung von Alzheimer
AU2001273942B2 (en) * 2000-04-20 2005-09-01 F. Hoffmann-La Roche Ag Pyrrolidine and piperidine derivatives and their use for the treament of neurodegenerative disorders
PE20020291A1 (es) * 2000-08-21 2002-04-17 Hoffmann La Roche Profarmacos para ligandos del receptor nmda
US20050260577A1 (en) * 2000-10-09 2005-11-24 Kay Double Detection of neurodegenerative disorders
US6951875B2 (en) * 2001-10-29 2005-10-04 Hoffmann-La Roche Inc. Conjugated aromatic compounds with a pyridine substituent
US7005432B2 (en) * 2002-05-16 2006-02-28 Hoffman-La Roche Inc. Substituted imidazol-pyridazine derivatives
CN101977606A (zh) * 2008-03-27 2011-02-16 伊沃泰克神经科学有限责任公司 使用nmda nr2b亚型选择性拮抗剂来治疗病症的方法
EP2734041A4 (de) * 2011-07-18 2015-03-25 Adolor Corp Verfahren zur herstellung von peripheren opioid-antagonisten-verbindungen und zwischenprodukten davon

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4410822A1 (de) * 1994-03-24 1995-09-28 Schering Ag Neue Piperidin-Derivate
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
TW498067B (en) * 1996-07-19 2002-08-11 Hoffmann La Roche 4-hydroxy-piperidine derivatives

Also Published As

Publication number Publication date
BR0011419A (pt) 2002-02-26
KR20020008850A (ko) 2002-01-31
AR024282A1 (es) 2002-09-25
DE60025348T2 (de) 2006-08-24
NO20015920D0 (no) 2001-12-04
US6310213B1 (en) 2001-10-30
CA2376091C (en) 2006-03-14
CZ20014349A3 (cs) 2002-05-15
EP1189886A1 (de) 2002-03-27
CN1142141C (zh) 2004-03-17
DE60025348D1 (de) 2006-03-30
EG26101A (en) 2013-02-17
HU228591B1 (hu) 2013-04-29
GT200000089A (es) 2001-11-29
YU86501A (sh) 2004-09-03
CA2376091A1 (en) 2000-12-14
KR100571162B1 (ko) 2006-04-17
MXPA01012585A (es) 2002-04-10
ATE315025T1 (de) 2006-02-15
IL146750A (en) 2006-12-10
MA26797A1 (fr) 2004-12-20
JO2260B1 (en) 2004-10-07
PE20010218A1 (es) 2001-02-28
RS50033B (sr) 2008-11-28
TNSN00125A1 (fr) 2005-11-10
ZA200109706B (en) 2003-02-26
SI1189886T1 (sl) 2006-04-30
JP2003501415A (ja) 2003-01-14
HRP20010885B1 (en) 2010-07-31
MY128818A (en) 2007-02-28
GC0000256A (en) 2006-11-01
PL352723A1 (en) 2003-09-08
WO2000075109A1 (en) 2000-12-14
AU770787B2 (en) 2004-03-04
NO320613B1 (no) 2005-12-27
ES2254183T3 (es) 2006-06-16
RU2242464C2 (ru) 2004-12-20
NO20015920L (no) 2001-12-04
HK1046412B (zh) 2004-07-09
HUP0201916A3 (en) 2003-05-28
JP3645856B2 (ja) 2005-05-11
CO5160328A1 (es) 2002-05-30
AU5218100A (en) 2000-12-28
PA8496601A1 (es) 2001-12-14
EP1189886B1 (de) 2006-01-04
TWI254043B (en) 2006-05-01
HRP20010885A2 (en) 2004-02-29
HUP0201916A2 (en) 2002-10-28
HK1046412A1 (en) 2003-01-10
DK1189886T3 (da) 2006-05-15
CN1354745A (zh) 2002-06-19
PL196053B1 (pl) 2007-11-30
TR200103532T2 (tr) 2002-05-21
CZ299483B6 (cs) 2008-08-13

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