IL145549A - Thienopyrimidine compounds, their production and use - Google Patents

Thienopyrimidine compounds, their production and use

Info

Publication number
IL145549A
IL145549A IL14554900A IL14554900A IL145549A IL 145549 A IL145549 A IL 145549A IL 14554900 A IL14554900 A IL 14554900A IL 14554900 A IL14554900 A IL 14554900A IL 145549 A IL145549 A IL 145549A
Authority
IL
Israel
Prior art keywords
production
thienopyrimidine compounds
thienopyrimidine
compounds
Prior art date
Application number
IL14554900A
Other languages
English (en)
Other versions
IL145549A0 (en
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of IL145549A0 publication Critical patent/IL145549A0/xx
Publication of IL145549A publication Critical patent/IL145549A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
IL14554900A 1999-03-24 2000-03-23 Thienopyrimidine compounds, their production and use IL145549A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7937199 1999-03-24
JP2000018019 2000-01-25
PCT/JP2000/001777 WO2000056739A1 (en) 1999-03-24 2000-03-23 Thienopyrimidine compounds, their production and use

Publications (2)

Publication Number Publication Date
IL145549A0 IL145549A0 (en) 2002-06-30
IL145549A true IL145549A (en) 2005-11-20

Family

ID=26420391

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14554900A IL145549A (en) 1999-03-24 2000-03-23 Thienopyrimidine compounds, their production and use

Country Status (28)

Country Link
US (1) US6340686B1 (no)
EP (1) EP1163244B1 (no)
JP (1) JP3240293B2 (no)
KR (2) KR100533483B1 (no)
CN (1) CN1349536A (no)
AR (1) AR023152A1 (no)
AT (1) ATE261449T1 (no)
AU (1) AU764019B2 (no)
BR (1) BR0009297A (no)
CA (1) CA2368108C (no)
CZ (1) CZ294747B6 (no)
DE (1) DE60008862T2 (no)
DK (1) DK1163244T3 (no)
ES (1) ES2212992T3 (no)
HK (1) HK1042495B (no)
HU (1) HUP0200550A3 (no)
ID (1) ID30393A (no)
IL (1) IL145549A (no)
MX (1) MXPA01009566A (no)
MY (1) MY124726A (no)
NO (1) NO20014603L (no)
NZ (1) NZ514737A (no)
OA (1) OA11920A (no)
PL (1) PL351202A1 (no)
PT (1) PT1163244E (no)
SK (1) SK13552001A3 (no)
TW (1) TWI225863B (no)
WO (1) WO2000056739A1 (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
CA2401379A1 (en) * 2000-02-29 2001-09-07 Junichi Kawakami Processes for the production of thienopyrimidine derivatives
US20030134863A1 (en) * 2000-04-13 2003-07-17 Shuichi Furuya Preventives/remedies for alzheimer's disease
WO2001095940A1 (fr) * 2000-06-14 2001-12-20 Takeda Chemical Industries, Ltd. Compositions a liberation continue
WO2002024230A1 (fr) * 2000-09-22 2002-03-28 Takeda Chemical Industries, Ltd. Preparations solides
WO2002043766A1 (fr) * 2000-11-29 2002-06-06 Takeda Chemical Industries, Ltd. Compositions medicinales et leur procede de preparation
AU2002221139A1 (en) * 2000-12-15 2002-06-24 Takeda Chemical Industries Ltd. Medicinal compositions of nonpeptidyl gonadotropin-releasing hormone agonist or antagonist, process for producing the same and use thereof
EP1374855A1 (en) * 2001-03-30 2004-01-02 Takeda Chemical Industries, Ltd. Medicinal solutions
US6740656B2 (en) 2001-08-02 2004-05-25 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
JP2005504034A (ja) 2001-08-02 2005-02-10 ニューロクライン バイオサイエンシーズ， インコーポレイテッド ゴナドトロピン放出性ホルモンレセプターアンタゴニストとしてのピリジノン誘導体およびピリダジノン誘導体
EP1414808A1 (en) 2001-08-02 2004-05-06 Neurocrine Biosciences, Inc. 1,2,4-triazin-3,5-diones as gonadotropin-releasing hormone receptor (gnrh) antagonists
US6939883B2 (en) 2001-08-02 2005-09-06 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
AU2002324586B2 (en) 2001-08-02 2008-04-24 Neurocrine Biosciences, Inc. 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists
WO2003064429A1 (fr) 2002-01-30 2003-08-07 Takeda Chemical Industries, Ltd. Thienopyrimidines, procedes de fabrication et d'utilisation correspondants
CA2481391A1 (en) 2002-04-12 2003-10-23 Takeda Pharmaceutical Company Limited Preventives/remedies for hotflash
JP2006508050A (ja) * 2002-08-21 2006-03-09 アストラゼネカ アクチボラグ ゴナドトロピン放出ホルモンのアンタゴニストとしてのチエノピロール化合物
KR101074462B1 (ko) 2003-01-29 2011-10-18 다케다 야쿠힌 고교 가부시키가이샤 티에노피리미딘 화합물 및 그 용도
GB0307777D0 (en) 2003-04-04 2003-05-07 Medical Res Council Conjugate compounds
WO2006044902A2 (en) * 2004-10-18 2006-04-27 Bwt Property, Inc. A solid-state lighting apparatus for navigational aids
US20090048273A1 (en) 2005-07-22 2009-02-19 Takeda Pharmaceutical Company Limited Premature ovulation preventive agent
US20110172249A1 (en) 2008-09-03 2011-07-14 Takeda Pharmaceutical Company Limted Method for improving absorbability of preparation, and preparation having improved absorbability
AU2013226661B2 (en) * 2012-02-28 2017-08-31 Tiumbio Co., Ltd Gonadotropin releasing hormone receptor antagonists, method for the preparation thereof and pharmaceutical composition comprising the same
EP2900675B1 (en) 2012-09-28 2019-03-06 Takeda Pharmaceutical Company Limited Production method of thienopyrimidine derivative
MX2017010945A (es) 2015-02-26 2018-07-06 Takeda Pharmaceuticals Co Preparacion solida.
HUE059101T2 (hu) 2016-09-30 2022-10-28 Myovant Sciences Gmbh Eljárások uterinális fibroidok és endometriózis kezelésére
AU2017334035B2 (en) 2016-09-30 2022-11-24 Myovant Sciences Gmbh Treatment of prostate cancer
KR101973074B1 (ko) * 2018-11-30 2019-04-26 주식회사 티움바이오 퓨로피리미딘 화합물의 염 및 결정형, 및 이를 포함하는 약학적 조성물
CN111943960B (zh) * 2019-07-29 2022-02-15 广东东阳光药业有限公司 取代的嘧啶二酮类化合物及其用途
CN111574534B (zh) * 2020-05-25 2021-06-04 东莞市东阳光新药研发有限公司 苯基取代的噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮类化合物及其用途
CN111909168B (zh) * 2020-07-31 2022-02-01 广东东阳光药业有限公司 含氮杂环基取代的嘧啶二酮类化合物及其用途
CN111925379B (zh) * 2020-07-31 2022-02-15 广东东阳光药业有限公司 含氮杂芳基取代的嘧啶二酮类化合物及其用途
CN112047957B (zh) * 2020-09-09 2022-02-01 广东东阳光药业有限公司 取代的嘧啶二酮类化合物及其用途
CN113754679B (zh) * 2020-09-09 2023-04-07 广东东阳光药业有限公司 取代的嘧啶二酮类化合物及其用途
CN113563304B (zh) * 2020-12-30 2022-06-28 上海博志研新药物技术有限公司 瑞卢戈利中间体及其制备方法
CN115260211B (zh) * 2021-04-29 2024-02-06 长春金赛药业有限责任公司 含噻吩稠环类衍生物、药物组合物及其制备方法和应用
CN113717149A (zh) * 2021-09-29 2021-11-30 成都伊诺达博医药科技有限公司 一种瑞卢戈利关键中间体及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW449600B (en) * 1994-04-19 2001-08-11 Takeda Chemical Industries Ltd Condensed-ring thiophene derivatives, their production and use
UY23948A1 (es) * 1995-02-08 2001-10-25 Takeda Chemical Industries Ltd Derivados de anillos condensados de tiofeno su producción y uso.
US5627786A (en) * 1995-02-10 1997-05-06 Micron Quantum Devices, Inc. Parallel processing redundancy scheme for faster access times and lower die area
WO1996028405A1 (fr) * 1995-03-10 1996-09-19 Nitto Chemical Industry Co., Ltd. Procede de production de derives de 1,2-ethanediol

Also Published As

Publication number Publication date
EP1163244B1 (en) 2004-03-10
KR20010090430A (ko) 2001-10-18
DE60008862T2 (de) 2005-01-27
CA2368108C (en) 2009-12-22
SK13552001A3 (sk) 2002-03-05
MY124726A (en) 2006-06-30
CA2368108A1 (en) 2000-09-28
KR20010015920A (ko) 2001-02-26
DK1163244T3 (da) 2004-07-12
CZ20013419A3 (cs) 2002-02-13
CN1349536A (zh) 2002-05-15
EP1163244A1 (en) 2001-12-19
PL351202A1 (en) 2003-03-24
KR100370981B1 (ko) 2003-02-06
AU764019B2 (en) 2003-08-07
WO2000056739A1 (en) 2000-09-28
OA11920A (en) 2006-04-12
NZ514737A (en) 2003-10-31
CZ294747B6 (cs) 2005-03-16
JP3240293B2 (ja) 2001-12-17
HK1042495B (zh) 2004-10-08
AU3326200A (en) 2000-10-09
US6340686B1 (en) 2002-01-22
PT1163244E (pt) 2004-07-30
ES2212992T3 (es) 2004-08-16
HUP0200550A2 (en) 2002-06-29
MXPA01009566A (es) 2002-05-14
BR0009297A (pt) 2001-12-18
KR100533483B1 (ko) 2005-12-05
NO20014603L (no) 2001-11-26
NO20014603D0 (no) 2001-09-21
DE60008862D1 (de) 2004-04-15
IL145549A0 (en) 2002-06-30
JP2001278884A (ja) 2001-10-10
AR023152A1 (es) 2002-09-04
HUP0200550A3 (en) 2004-07-28
ID30393A (id) 2001-11-29
HK1042495A1 (en) 2002-08-16
TWI225863B (en) 2005-01-01
ATE261449T1 (de) 2004-03-15

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees