IL141445A - Extended release buccal bioadhesive tablet - Google Patents
Extended release buccal bioadhesive tabletInfo
- Publication number
- IL141445A IL141445A IL14144599A IL14144599A IL141445A IL 141445 A IL141445 A IL 141445A IL 14144599 A IL14144599 A IL 14144599A IL 14144599 A IL14144599 A IL 14144599A IL 141445 A IL141445 A IL 141445A
- Authority
- IL
- Israel
- Prior art keywords
- extended release
- bioadhesive tablet
- buccal bioadhesive
- release buccal
- tablet
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9784398P | 1998-08-25 | 1998-08-25 | |
US09/379,310 US6248358B1 (en) | 1998-08-25 | 1999-08-23 | Bioadhesive progressive hydration tablets and methods of making and using the same |
PCT/US1999/019260 WO2000010536A1 (fr) | 1998-08-25 | 1999-08-24 | Comprime bioadhesif a liberation prolongee destine a etre administre par voie orale |
Publications (2)
Publication Number | Publication Date |
---|---|
IL141445A0 IL141445A0 (en) | 2002-03-10 |
IL141445A true IL141445A (en) | 2005-12-18 |
Family
ID=22265404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14144599A IL141445A (en) | 1998-08-25 | 1999-08-24 | Extended release buccal bioadhesive tablet |
Country Status (26)
Country | Link |
---|---|
US (1) | US6248358B1 (fr) |
EP (1) | EP1105104B1 (fr) |
JP (2) | JP5411398B2 (fr) |
KR (1) | KR100716702B1 (fr) |
CN (2) | CN1259903C (fr) |
AR (1) | AR036972A1 (fr) |
AT (1) | ATE306253T1 (fr) |
AU (1) | AU754880B2 (fr) |
BR (1) | BR9913239B1 (fr) |
CA (1) | CA2341375C (fr) |
DE (1) | DE69927694T2 (fr) |
DK (1) | DK1105104T3 (fr) |
ES (1) | ES2251220T3 (fr) |
HK (1) | HK1034895A1 (fr) |
HU (1) | HU226591B1 (fr) |
IL (1) | IL141445A (fr) |
MA (1) | MA24964A1 (fr) |
MX (1) | MXPA01002007A (fr) |
MY (2) | MY125919A (fr) |
NO (1) | NO331255B1 (fr) |
NZ (1) | NZ509963A (fr) |
PE (1) | PE20001036A1 (fr) |
RU (1) | RU2227022C2 (fr) |
UA (1) | UA78967C2 (fr) |
WO (1) | WO2000010536A1 (fr) |
ZA (1) | ZA995445B (fr) |
Families Citing this family (46)
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US6624200B2 (en) * | 1998-08-25 | 2003-09-23 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
AU2005203703B2 (en) * | 1998-08-25 | 2007-05-24 | Columbia Laboratories (Bermuda) Limited | Bioadhesive progressive hydration tablets |
US7803392B2 (en) * | 2000-12-27 | 2010-09-28 | University Of Kentucky Research Foundation | pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules |
AU2002257430A1 (en) * | 2001-05-01 | 2002-11-11 | Mcgill University | Androgen-mediated neuroprotection and uses thereof |
US8425892B2 (en) * | 2001-10-29 | 2013-04-23 | Columbia Laboratories, Inc. | Extended, controlled-release pharmaceutical compositions using charged polymers |
CN101327326A (zh) * | 2001-10-29 | 2008-12-24 | 哥伦比亚实验室(百慕大群岛)有限公司 | 阴道给药治疗骨盆痛和不孕症的抗节律障碍剂 |
US7709026B2 (en) | 2001-10-29 | 2010-05-04 | Columbia Laboratories, Inc. | Low concentration of peroxide for treating or preventing vaginal infections |
US20030114394A1 (en) * | 2001-10-29 | 2003-06-19 | Levine Howard L. | Vaginally administered anti-dysrhythmic agents for treating pelvic pain |
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US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
MY142204A (en) * | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
CN1684667A (zh) * | 2002-08-02 | 2005-10-19 | 兰贝克赛实验室有限公司 | 贮藏稳定的福辛普利钠片剂 |
EP1562548A1 (fr) * | 2002-11-14 | 2005-08-17 | Shear/Kershman Laboratories, Inc. | Systeme d'administration de testosterone par voie orale a liberation prolongee amelioree |
SE0302947D0 (sv) | 2003-01-24 | 2003-11-07 | Magle Ab | A composition material for transmucosal delivery |
WO2004064811A1 (fr) * | 2003-01-24 | 2004-08-05 | Magle Holding Ab | Matiere de composition pour administration a travers la muqueuse |
DE602005025755D1 (de) | 2004-06-04 | 2011-02-17 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
CA2576386A1 (fr) * | 2004-08-13 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Preparation d'une pastille a autorisation de sortie elargie, contenant du pramipexole ou un sel de pramipexole pharmaceutiquement acceptable, procede de fabrication et d'utilisation de cette pastille |
PL1789021T3 (pl) * | 2004-08-13 | 2012-04-30 | Boehringer Ingelheim Int | Preparat tabletkowy o przedłużonym uwalnianiu zawierający pramipeksol lub jego farmaceutycznie dopuszczalną sól |
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US20070048369A1 (en) * | 2005-08-26 | 2007-03-01 | National Starch And Chemical Investment Holding Corporation | Mucosal delivery tablet |
CN101330903B (zh) | 2005-12-13 | 2015-07-08 | 生物递送科学国际公司 | 防滥用的经黏膜给药装置 |
US20090041844A1 (en) * | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
US20090098202A1 (en) * | 2006-02-10 | 2009-04-16 | Boehringer Ingelheim International Gmbh | Extended Release Formulation |
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EP1837020A1 (fr) | 2006-03-24 | 2007-09-26 | Bioalliance Pharma | Vehicule bioadhesif pour les muqueuses pour delivrer lentement des principes actifs |
US20070248655A1 (en) * | 2006-04-21 | 2007-10-25 | Haley Jeffrey T | Lenticular shaped protective mouth sore discs |
EP1872775A1 (fr) * | 2006-06-29 | 2008-01-02 | Polichem S.A. | Emploi d'une matrice hydrophile contenant un dérivé polyacrylique, un éther de cellulose et un désintégrant, pour la production d'un médicament pour le traitement des troubles génitales d'une femme |
DK2054031T3 (en) | 2006-07-21 | 2016-05-17 | Biodelivery Sciences Int Inc | Transmucosal delivery devices with improved uptake |
US20100028447A1 (en) | 2007-01-22 | 2010-02-04 | Targacept, Inc. | Intranasal, Buccal, And Sublingual Administration Of Metanicotine Analogs |
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US8828981B2 (en) | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
WO2008121767A2 (fr) | 2007-03-28 | 2008-10-09 | President And Fellows Of Harvard College | Polypeptides cousus |
EP1987820A1 (fr) * | 2007-05-04 | 2008-11-05 | Christian Fiala, Ph. D. | Misoprostole à libération lente pour applications obstétriques et/ou gynécologiques |
EP2293779A1 (fr) * | 2008-04-24 | 2011-03-16 | Evestra, Inc. | Formes galéniques contraceptives orales renfermant un progestogène dispersé dans un polymère gastrorésistant et renfermant en outre un strogène |
EP2163240A1 (fr) * | 2008-09-12 | 2010-03-17 | Universita' Degli Studi Di Genova | Méthode pour la production des matrices compactes bioadhésives |
MX343193B (es) | 2009-06-18 | 2016-10-26 | Allergan Inc | Administracion segura de desmopresina. |
WO2012021876A2 (fr) | 2010-08-13 | 2012-02-16 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques |
KR101944367B1 (ko) | 2011-08-18 | 2019-01-31 | 바이오딜리버리 사이언시스 인터내셔널 인코포레이티드 | 부프레노르핀 운반용 약물남용 억제 점막 부착 장치 |
AU2012326026B2 (en) | 2011-10-18 | 2017-04-13 | Aileron Therapeutics, Inc. | Peptidomimetic macrocyles |
US9901539B2 (en) | 2011-12-21 | 2018-02-27 | Biodelivery Sciences International, Inc. | Transmucosal drug delivery devices for use in chronic pain relief |
US8987414B2 (en) | 2012-02-15 | 2015-03-24 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
KR102112373B1 (ko) | 2012-02-15 | 2020-05-18 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방체 마크로사이클 |
SG11201503052RA (en) | 2012-11-01 | 2015-05-28 | Aileron Therapeutics Inc | Disubstituted amino acids and methods of preparation and use thereof |
WO2016049359A1 (fr) | 2014-09-24 | 2016-03-31 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques et leurs utilisations |
AU2016235424A1 (en) | 2015-03-20 | 2017-10-05 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
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1999
- 1999-08-23 US US09/379,310 patent/US6248358B1/en not_active Expired - Lifetime
- 1999-08-24 DK DK99942454T patent/DK1105104T3/da active
- 1999-08-24 BR BRPI9913239-7A patent/BR9913239B1/pt not_active IP Right Cessation
- 1999-08-24 IL IL14144599A patent/IL141445A/xx not_active IP Right Cessation
- 1999-08-24 ES ES99942454T patent/ES2251220T3/es not_active Expired - Lifetime
- 1999-08-24 RU RU2001107846/15A patent/RU2227022C2/ru not_active IP Right Cessation
- 1999-08-24 JP JP2000565858A patent/JP5411398B2/ja not_active Expired - Fee Related
- 1999-08-24 CN CNB998122009A patent/CN1259903C/zh not_active Expired - Fee Related
- 1999-08-24 UA UA2001031967A patent/UA78967C2/uk unknown
- 1999-08-24 CA CA002341375A patent/CA2341375C/fr not_active Expired - Fee Related
- 1999-08-24 MX MXPA01002007A patent/MXPA01002007A/es not_active IP Right Cessation
- 1999-08-24 WO PCT/US1999/019260 patent/WO2000010536A1/fr active IP Right Grant
- 1999-08-24 DE DE69927694T patent/DE69927694T2/de not_active Expired - Lifetime
- 1999-08-24 NZ NZ509963A patent/NZ509963A/en not_active IP Right Cessation
- 1999-08-24 HU HU0103218A patent/HU226591B1/hu not_active IP Right Cessation
- 1999-08-24 AT AT99942454T patent/ATE306253T1/de active
- 1999-08-24 AU AU55826/99A patent/AU754880B2/en not_active Ceased
- 1999-08-24 KR KR1020017002347A patent/KR100716702B1/ko not_active IP Right Cessation
- 1999-08-24 CN CNA2005101375941A patent/CN1879608A/zh active Pending
- 1999-08-24 EP EP99942454A patent/EP1105104B1/fr not_active Expired - Lifetime
- 1999-08-25 MA MA25744A patent/MA24964A1/fr unknown
- 1999-08-25 MY MYPI99003649A patent/MY125919A/en unknown
- 1999-08-25 ZA ZA9905445A patent/ZA995445B/xx unknown
- 1999-08-25 AR ARP990104253A patent/AR036972A1/es active IP Right Grant
- 1999-08-25 PE PE1999000855A patent/PE20001036A1/es not_active Application Discontinuation
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2000
- 2000-06-20 MY MYPI20002772A patent/MY133365A/en unknown
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2001
- 2001-02-23 NO NO20010919A patent/NO331255B1/no not_active IP Right Cessation
- 2001-07-13 HK HK01104891A patent/HK1034895A1/xx not_active IP Right Cessation
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2010
- 2010-07-02 JP JP2010151682A patent/JP2010248231A/ja active Pending
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