IL139617A0 - Biodegradable sustained release alginate gels - Google Patents

Biodegradable sustained release alginate gels

Info

Publication number
IL139617A0
IL139617A0 IL13961799A IL13961799A IL139617A0 IL 139617 A0 IL139617 A0 IL 139617A0 IL 13961799 A IL13961799 A IL 13961799A IL 13961799 A IL13961799 A IL 13961799A IL 139617 A0 IL139617 A0 IL 139617A0
Authority
IL
Israel
Prior art keywords
sustained release
alginate gels
biodegradable sustained
release alginate
biodegradable
Prior art date
Application number
IL13961799A
Other languages
English (en)
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL139617A0 publication Critical patent/IL139617A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fats And Perfumes (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13961799A 1998-05-18 1999-05-14 Biodegradable sustained release alginate gels IL139617A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/080,832 US6432449B1 (en) 1998-05-18 1998-05-18 Biodegradable sustained-release alginate gels
PCT/US1999/010737 WO1999059549A1 (en) 1998-05-18 1999-05-14 Biodegradable sustained-release alginate gels

Publications (1)

Publication Number Publication Date
IL139617A0 true IL139617A0 (en) 2002-02-10

Family

ID=22159900

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13961799A IL139617A0 (en) 1998-05-18 1999-05-14 Biodegradable sustained release alginate gels

Country Status (25)

Country Link
US (2) US6432449B1 (xx)
EP (1) EP1079811B1 (xx)
JP (1) JP2002515419A (xx)
KR (1) KR20010025023A (xx)
CN (1) CN1309556A (xx)
AT (1) ATE343378T1 (xx)
AU (1) AU3993999A (xx)
BG (1) BG65397B1 (xx)
BR (1) BR9910553A (xx)
CA (1) CA2331446C (xx)
CY (1) CY1105944T1 (xx)
DE (1) DE69933763T2 (xx)
DK (1) DK1079811T3 (xx)
EA (1) EA003670B1 (xx)
ES (1) ES2275341T3 (xx)
HU (1) HUP0101895A3 (xx)
IL (1) IL139617A0 (xx)
NO (1) NO20005564L (xx)
NZ (1) NZ507943A (xx)
PL (1) PL199499B1 (xx)
PT (1) PT1079811E (xx)
RS (1) RS49841B (xx)
SK (1) SK16752000A3 (xx)
WO (1) WO1999059549A1 (xx)
ZA (1) ZA200006299B (xx)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010007673A1 (en) * 1999-11-12 2001-07-12 Merrill Seymour Goldenberg Sustained-release delayed gels
KR100426636B1 (ko) * 2001-05-18 2004-04-08 한국과학기술연구원 주사 가능한 젤 상의 조성물 및 그의 제조방법
WO2002100425A1 (en) * 2001-06-11 2002-12-19 Ltt Institute Co., Ltd. Aggregate composition for sustained-release preparation, process for producing the same, and sustained-release preparation containing the same
WO2003062199A2 (en) * 2002-01-16 2003-07-31 Agency For Disease Diagnosis And Prevention Pace-a microspheres for delivery of antigens
US6592852B1 (en) * 2002-04-25 2003-07-15 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Zinc citrate beads in oral compositions
KR100523953B1 (ko) * 2002-08-27 2005-10-25 주식회사 엘지생명과학 천연다당류와 히알루론산의 마이크로비드 및 이의 제조 방법
KR100507545B1 (ko) * 2002-09-03 2005-08-09 주식회사 엘지생명과학 히알루론산 유도체 및 그의 제조방법
JP4459543B2 (ja) 2003-03-17 2010-04-28 株式会社メドジェル 徐放性ハイドロゲル製剤
SI1682184T1 (sl) * 2003-11-04 2014-02-28 Lek Pharmaceuticals D.D. Stabilen farmacevtski sestavek, obsegajoč faktor za stimulacijo kolonije granulocitov
CN1319525C (zh) * 2004-09-16 2007-06-06 北京圣医耀科技发展有限责任公司 紫杉醇－海藻酸钠微球血管栓塞剂及其制备
EP1803464A4 (en) * 2004-09-17 2009-09-09 Cellgentech Inc TOPICAL PREPARATION FOR THE TREATMENT OF SKIN DISEASES
JP5367266B2 (ja) * 2004-10-12 2013-12-11 エフエムシー バイオポリマー エイエス 自己ゲル化性アルギネート系及びその使用
US8318210B2 (en) * 2005-02-28 2012-11-27 Neos Therapeutics, Lp Compositions and methods of making sustained release liquid formulations
US9119901B2 (en) 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
US8414907B2 (en) 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US8663686B2 (en) * 2005-05-09 2014-03-04 University Of Washington Biodegradable chitosan-PEG compositions and methods of use
US9012605B2 (en) 2006-01-23 2015-04-21 Amgen Inc. Crystalline polypeptides
JP5248492B2 (ja) * 2006-07-14 2013-07-31 エフエムシー バイオポリマー エイエス 低分子量アルギネートを含むヒドロゲルおよびそれから製造されたバイオ構造物
DE102007039871A1 (de) * 2007-08-21 2009-02-26 Friedrich-Baur-Gmbh Weichgewebe-Implantat mit antibakterieller Wirkung
KR20100063744A (ko) * 2007-08-28 2010-06-11 에프엠씨 코포레이션 지연된 자가-겔화 알기네이트 시스템 및 이의 용도
ES2327375B1 (es) 2007-11-14 2010-08-05 Universidad Del Pais Vasco Empleo de microparticulas para su uso como vacunas y la liberacion de moleculas biologicamente activas.
US20090183503A1 (en) * 2008-01-18 2009-07-23 Alberto Verdesi Exhaust apparatus
US20100015240A1 (en) * 2008-07-16 2010-01-21 Danielle Biggs Process for preparing microparticles containing bioactive peptides
WO2010032242A1 (en) * 2008-09-17 2010-03-25 Beta O2 Technologies Ltd. Optimization of alginate encapsulation of islets for transplantation
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
WO2011057133A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Fragmented hydrogels
US20130149349A1 (en) 2010-06-03 2013-06-13 Indiana University Research And Technology Corporation Use of compounds with thrombopoietic activity to promote bone growth and healing
WO2011154941A2 (en) 2010-06-07 2011-12-15 Beta-O2 Technologies Ltd. Multiple-layer immune barrier for donor cells
CA2804842A1 (en) 2010-07-09 2012-01-12 Board Of Regents Of The University Of Texas System Biodegradable scaffolds
KR20140018315A (ko) 2011-03-25 2014-02-12 암젠 인크 항스클러로스틴 항체 결정 및 이의 제제
CN102489027B (zh) * 2011-12-12 2014-06-04 山东凯翔生物化工有限公司 一种葡萄糖酸内酯节能浓缩方法及装置
CN103830266A (zh) * 2013-04-24 2014-06-04 杨亚勤 部分氧化海藻酸钠羧甲基化衍生物的制备方法和应用
RU2548777C2 (ru) * 2013-07-09 2015-04-20 Александр Александрович Кролевец Способ получения частиц инкапсулированных жирорастворимой полимерной оболочкой солей металлов, обладающих супрамолекулярными свойствами
MX2017000526A (es) 2014-07-14 2017-08-02 Amgen Inc Formulaciones de anticuerpos cristalinos.
AU2015289874A1 (en) 2014-07-14 2017-02-02 Amgen Inc. Crystalline antibody formulations
US10835604B2 (en) * 2015-08-13 2020-11-17 Northeastern University Biomaterials for combined radiotherapy and immunotherapy of cancer
EP3501553A1 (en) * 2017-12-21 2019-06-26 Association for the Advancement of Tissue Engineering and Cell based Technologies & Therapies (A4TEC) - Associação Hydrogel comprising manganese, methods and uses thereof
CN109293138A (zh) * 2018-10-08 2019-02-01 曹布道 一种养殖污水净化处理方法
EP3986378A1 (en) 2019-06-21 2022-04-27 Alfasigma S.p.A. Pharmaceutical compositions in the form of gel containing xyloglucan and alcohols for the controlled release of active ingredients
CN112426981B (zh) * 2020-11-30 2021-12-28 西安交通大学 一种金属离子交联水凝胶及制备方法和应用
CN114685778B (zh) * 2020-12-30 2023-10-17 苏州艾博生物科技有限公司 长循环阳离子脂质体的合成方法
CN112843328B (zh) * 2021-02-25 2022-05-13 山东大学 一种具有抑菌作用的鲍鱼壳粉/ZnO复合材料掺杂的智能水凝胶伤口敷料的制备方法
CN114539442A (zh) * 2022-04-02 2022-05-27 青岛海之林生物科技开发有限公司 一种脂溶性藻酸乙酯及其制备方法与应用
CN115850533B (zh) * 2022-09-28 2023-07-21 青岛格诚经纬生物科技有限公司 一种海藻酸材料及其制备方法、应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640741A (en) * 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
JPS5416979B2 (xx) * 1972-01-08 1979-06-26
US4401456A (en) * 1980-01-09 1983-08-30 The United States Of America As Represented By The Secretary Of Agriculture Controlled release of bioactive materials using alginate gel beads
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US4789516A (en) * 1983-04-15 1988-12-06 Damon Biotech, Inc Production of sustained released system
US4744933A (en) * 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
CA1215922A (en) * 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US5147861A (en) * 1986-06-30 1992-09-15 Fidia S.P.A. Esters of alginic acid
JPS645460A (en) * 1987-06-29 1989-01-10 Sanei Kagaku Kogyo Kk Production of delaying gelatinous material
WO1993009176A2 (en) * 1991-10-29 1993-05-13 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
US5656297A (en) * 1992-03-12 1997-08-12 Alkermes Controlled Therapeutics, Incorporated Modulated release from biocompatible polymers
GB2275686B (en) * 1993-03-03 1997-04-30 Johnson & Johnson Medical Swellable wound dressing materials
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
WO1996000081A1 (en) * 1994-06-24 1996-01-04 Immunex Corporation Controlled release polypeptide compositions and methods of treating inflammatory bowel disease
US5660859A (en) * 1994-12-29 1997-08-26 Mcneil-Ppc, Inc. Gelling agent for polyethylene glycol
US5773416A (en) * 1995-10-25 1998-06-30 The Regents Of The University Of California Methods for restoring or enhancing reproductive function in reproductively impaired hosts
AU2246097A (en) * 1996-01-25 1997-08-20 Eli Lilly And Company Obesity protein analog compounds and formulations thereof
US6656508B2 (en) * 1997-04-17 2003-12-02 Amgen Inc. Sustained-release alginate gels
SK286437B6 (sk) * 1997-05-16 2008-10-07 Amgen, Inc. Gélotvorná farmaceutická kompozícia s predĺženým uvoľňovaním a oneskorenou tvorbou gélu a jej použitie
GB2339442B (en) * 1998-07-09 2002-06-05 Smith International Downhole tension swivel sub

Also Published As

Publication number Publication date
ES2275341T3 (es) 2007-06-01
WO1999059549A1 (en) 1999-11-25
CA2331446C (en) 2004-03-16
EA003670B1 (ru) 2003-08-28
PL199499B1 (pl) 2008-09-30
ATE343378T1 (de) 2006-11-15
CA2331446A1 (en) 1999-11-25
PT1079811E (pt) 2007-01-31
JP2002515419A (ja) 2002-05-28
DE69933763T2 (de) 2007-10-04
US20020168406A1 (en) 2002-11-14
EP1079811B1 (en) 2006-10-25
HUP0101895A2 (hu) 2001-10-28
AU3993999A (en) 1999-12-06
NO20005564L (no) 2001-01-18
EP1079811A1 (en) 2001-03-07
YU69400A (sh) 2003-02-28
BG104943A (en) 2001-07-31
SK16752000A3 (sk) 2001-09-11
EA200001200A1 (ru) 2001-04-23
HUP0101895A3 (en) 2004-01-28
KR20010025023A (ko) 2001-03-26
NZ507943A (en) 2003-08-29
ZA200006299B (en) 2001-05-30
CN1309556A (zh) 2001-08-22
NO20005564D0 (no) 2000-11-03
CY1105944T1 (el) 2011-04-06
DE69933763D1 (de) 2006-12-07
BG65397B1 (bg) 2008-06-30
BR9910553A (pt) 2001-01-30
DK1079811T3 (da) 2007-02-26
PL344337A1 (en) 2001-11-05
US6432449B1 (en) 2002-08-13
RS49841B (sr) 2008-08-07

Similar Documents

Publication Publication Date Title
IL139617A0 (en) Biodegradable sustained release alginate gels
DK0975333T3 (da) Alginatgel med langvarig frigörelse
YU58599A (sh) Gelovi sa usporenim podržanim oslobađanjem
MXPA01007710A (es) Agente de secado por congelacion que contiene paramilon, su produccion y uso.
HUP0100221A3 (en) Sustained release compositions, process for producing the same and utilization thereof
IL147803A0 (en) 28-epirapalogs
BG101132A (en) Pyridoanilated thienyl and furanyl oxazolidinons
ID23809A (id) Komposisi-komposisi alginat yang dapat dituang
HUP0202880A3 (en) Sustained release compositions, process for producing the same and use thereof
AU3436601A (en) Decoding of array sensors with microspheres
AU5623599A (en) Aza-cyclodepsipeptides and their use as antiparasitics
AU3661799A (en) Horticultural compositions comprising amphoteric polymers and methods of utilizing the horticultural compositions
AU2003200609A1 (en) Biodegradable sustained-release alginate gels
ZA983205B (en) Sustained release compositions and the process for their preparation
EP1021610A4 (en) PHOTO-STABILIZING POLYMER COMPOSITIONS AND PROCESSES FOR PRODUCING THE SAME
SI1079811T1 (sl) Boirazgradljivi alginatni geli za neprekinjeno sproscanje
GB2356665B (en) Clipping system
GB9913806D0 (en) Scent system
GB9811197D0 (en) T shaped suspender
ZA954708B (en) Biodegradable sustained release composition
GB9920214D0 (en) Audio messages
GB9815539D0 (en) Invisible flag
GB9916506D0 (en) Compositions and methods
GB9928549D0 (en) Compositions and methods
GB9916503D0 (en) Compositions and methods