IL139173A0 - Topical formulation comprising poloxamers and further microbicides and an applicator - Google Patents

Topical formulation comprising poloxamers and further microbicides and an applicator

Info

Publication number
IL139173A0
IL139173A0 IL13917399A IL13917399A IL139173A0 IL 139173 A0 IL139173 A0 IL 139173A0 IL 13917399 A IL13917399 A IL 13917399A IL 13917399 A IL13917399 A IL 13917399A IL 139173 A0 IL139173 A0 IL 139173A0
Authority
IL
Israel
Prior art keywords
poloxamers
applicator
topical formulation
microbicides
further microbicides
Prior art date
Application number
IL13917399A
Other languages
English (en)
Original Assignee
Infectio Recherche Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002257001A external-priority patent/CA2257001A1/en
Application filed by Infectio Recherche Inc filed Critical Infectio Recherche Inc
Publication of IL139173A0 publication Critical patent/IL139173A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0233—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
    • A61M3/0254—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped
    • A61M3/0262—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped manually, e.g. by squeezing a bulb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0279—Cannula; Nozzles; Tips; their connection means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1042—Alimentary tract
    • A61M2210/1067—Anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/14—Female reproductive, genital organs
    • A61M2210/1475—Vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
IL13917399A 1998-04-21 1999-04-21 Topical formulation comprising poloxamers and further microbicides and an applicator IL139173A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2235427 1998-04-21
CA002257001A CA2257001A1 (en) 1998-12-23 1998-12-23 Method and formulations for prevention of infection of mucosae and/or skin and development of a vaginal/ano-rectal applicator for the delivery of topical formulations
PCT/CA1999/000359 WO1999053897A2 (en) 1998-04-21 1999-04-21 Topical formulation comprising poloxamers and further microbicides, and an applicator

Publications (1)

Publication Number Publication Date
IL139173A0 true IL139173A0 (en) 2001-11-25

Family

ID=25680156

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13917399A IL139173A0 (en) 1998-04-21 1999-04-21 Topical formulation comprising poloxamers and further microbicides and an applicator

Country Status (22)

Country Link
US (2) US6500460B1 (de)
EP (2) EP1079802B1 (de)
JP (1) JP4665075B2 (de)
KR (1) KR20010042875A (de)
CN (2) CN100374110C (de)
AR (1) AR018194A1 (de)
AT (1) ATE355050T1 (de)
AU (1) AU762461B2 (de)
BR (1) BR9909801A (de)
DE (1) DE69935325T2 (de)
ES (1) ES2284250T3 (de)
HK (1) HK1037861A1 (de)
HU (1) HUP0101507A3 (de)
ID (1) ID26791A (de)
IL (1) IL139173A0 (de)
NO (1) NO20005310L (de)
NZ (1) NZ507609A (de)
PL (1) PL344111A1 (de)
RU (1) RU2224503C2 (de)
SK (1) SK15822000A3 (de)
TR (2) TR200102067T2 (de)
WO (1) WO1999053897A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE355050T1 (de) * 1998-04-21 2006-03-15 Infectio Recherche Inc Topische formulierung enthaltend poloxamere und weitere mikrobizide
US6835717B2 (en) * 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
US7465295B2 (en) 2000-10-20 2008-12-16 Bergeron Michel G Applicator for the delivery of topical formulations into mucosal cavities
AU2003275069A1 (en) * 2002-09-20 2004-04-08 La Jolla Biosciences Compositions and methods for preventing infection
JP2006520374A (ja) * 2003-03-14 2006-09-07 エピスタム リミテッド 非ウィルス性上皮損傷の治療および／または予防
DE10328942A1 (de) * 2003-06-27 2005-01-27 Lts Lohmann Therapie-Systeme Ag Transmukosale Darreichungsformen mit verminderter Schleimhautirritation
CN1311873C (zh) * 2004-06-30 2007-04-25 上海复康医药科技发展有限公司 一种温度敏感的阴道用原位凝胶制剂
US20060127459A1 (en) * 2004-12-15 2006-06-15 Lei Huang Urogenital infection inhibition
US7745158B2 (en) * 2005-12-14 2010-06-29 Kimberly-Clark Worldwide, Inc. Detection of secreted aspartyl proteases from Candida species
US20070134747A1 (en) * 2005-12-14 2007-06-14 Kimberly-Clark Worldwide, Inc. Detection of secreted lipase proteins from Candida species
CN100463675C (zh) * 2007-01-29 2009-02-25 高章圈 一种可溶性缓释外用避孕药
US20080269205A1 (en) * 2007-04-27 2008-10-30 Ondine International, Ltd. Methods to prevent vertical transmission of infectious diseases
DE102008006416A1 (de) * 2008-01-28 2009-07-30 Mayer, Thomas, Dr. med. Clindamycin zur Verwendung bei der Behandlung oder Vorbeugung der bakteriellen Vaginosis
US8591961B2 (en) 2008-09-04 2013-11-26 Allergan, Inc. Aesthetic treatment of scars and aging skin
US8308678B2 (en) * 2008-09-23 2012-11-13 Mcneil-Ppc, Inc. Pre-filled applicator device
US8236768B2 (en) 2008-10-03 2012-08-07 3B Pharmaceuticals, Inc. Topical antiviral formulations
US8192393B2 (en) 2008-10-07 2012-06-05 Christcot Medical Company Method and apparatus for inserting a rectal suppository
US9662481B2 (en) 2008-10-07 2017-05-30 Cristcot Llc Method and apparatus for inserting a rectal suppository
US9629856B2 (en) 2010-03-03 2017-04-25 Anteis Sa Compositions and methods for the treatment of skin diseases and disorders using antimicrobial peptide sequestering compounds
WO2012037193A2 (en) 2010-09-17 2012-03-22 Brassica Protection Products Llc Formulations for treatment with glucosinolate
WO2014063122A1 (en) 2012-10-19 2014-04-24 Christcot Inc. Suppository insertion device, suppository, and method of manufacturing a suppository
WO2014210156A1 (en) 2013-06-25 2014-12-31 Mission Pharmacal Company Novel formulations for the treatment of vaginal disorders
US11071745B2 (en) 2014-07-07 2021-07-27 Elian Llc Viral prophylaxis treatment methods and pre-exposure prophylaxis kits
CN106794336B (zh) * 2014-07-07 2022-01-11 艾利安有限责任公司 病毒预防性治疗方法和暴露前预防性试剂盒
US9474885B2 (en) * 2015-01-10 2016-10-25 Nine Medical, Inc. Methods and devices to prevent premature birth
JP7061967B2 (ja) 2016-05-12 2022-05-02 クリストコット エルエルシー 使い捨て座薬挿入装置及び方法
ITUA20164065A1 (it) * 2016-06-01 2017-12-01 Probiotical Spa Composizioni in gel per applicazioni topiche a base di batteri, preparazione delle stesse e loro usi.
WO2018078336A1 (en) * 2016-10-28 2018-05-03 Reckitt Benckiser Llc Feminine hygiene products
CN107224663B (zh) * 2017-07-21 2019-12-03 新乡医学院第一附属医院 一种泌尿外科用尿道给药器
US11446257B2 (en) 2018-09-27 2022-09-20 BioPhysics Pharma, Inc. Transdermal drug delivery system
CN110624173B (zh) * 2019-10-12 2022-02-08 南通大学附属医院 一种无创妇科护理用药装置
CN115040501B (zh) * 2022-06-06 2023-09-12 中国中医科学院广安门医院 顺-13-十八碳烯酸或其盐化合物在制备促进受损皮肤和/或黏膜愈合的药物中的应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US563349A (en) * 1896-07-07 Wash boiler attachment
US2683456A (en) * 1953-03-02 1954-07-13 Louis A Pierson Rectal medicator
DE3324780A1 (de) 1983-07-08 1985-01-17 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Vorrichtung zur intra-analen applikation von fluessigen oder pastoesen wirkstoffzubereitungen
DE3441609A1 (de) 1984-11-14 1986-05-22 Bramlage Gmbh, 2842 Lohne Salbenapplikator
DE3513645A1 (de) * 1985-04-16 1986-10-16 Dr. Kade Pharmazeutische Fabrik GmbH, 1000 Berlin Applikator fuer haemorrhoidalsalben
FR2585575B1 (fr) * 1985-08-01 1989-03-03 Pf Medicament Compositions pharmaceutiques a activite keratolytique sous forme de gel comportant de l'acide salicylique hydro-alcoolique
US5057310A (en) * 1986-11-06 1991-10-15 Hill Ira D Method of manufacturing oral hygiene preparations containing active SnF.sub.
JPS63253026A (ja) * 1987-04-10 1988-10-20 Masahiko Ito エイズ・ウイルス増殖抑制剤
US4980152A (en) * 1987-08-06 1990-12-25 Marion Laboratories Oral preparation
JPH0624498B2 (ja) * 1987-11-30 1994-04-06 ▲ひろ▼陸 佐藤 噴射装置の噴射ノズル
US5098711A (en) * 1988-11-14 1992-03-24 Ira Hill Method of treating the oral cavity with dental floss containing chemotherapeutic agents
EP0386960A3 (de) * 1989-03-07 1991-10-23 American Cyanamid Company Pharmazeutische Zusammensetzungen zur Verwendung als Wirkstoffabgabevehikel und/oder als Wundverband
US5298260A (en) * 1990-05-01 1994-03-29 Mediventures, Inc. Topical drug delivery with polyoxyalkylene polymer thermoreversible gels adjustable for pH and osmolality
US5593683A (en) * 1990-05-01 1997-01-14 Mdv Technologies, Inc. Method of making thermoreversible polyoxyalkylene gels
US5185153A (en) * 1990-10-04 1993-02-09 The Research Foundation Of The State University Of New York Agents effecting the lysis of oral bacteria
JPH07501045A (ja) * 1991-06-20 1995-02-02 セプ、ホールディングス、インコーポレーテッド ヘルペスによる病変部の治癒を促進する局所用組成物
AT408191B (de) 1991-08-19 2001-09-25 Haemosan Erzeugung Pharmazeuti Verfahren zur inaktivierung von prionen
US5260066A (en) * 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
CN2171372Y (zh) * 1993-03-13 1994-07-13 谭运江 直肠液体注药器
CN1054504C (zh) * 1993-03-15 2000-07-19 科尔加特·帕尔莫利弗公司 洁牙剂
CN2183786Y (zh) * 1993-10-22 1994-11-30 盖国忠 双腔肛点器
US5424060A (en) * 1993-10-25 1995-06-13 Church & Dwight Co., Inc. Dentifrice composition containing stabilized sodium percarbonate
US6203803B1 (en) * 1994-12-14 2001-03-20 Societe L'oreal S.A. Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained
DE69519393T2 (de) * 1994-07-13 2001-04-26 Alza Corp Zusammensetzung und verfahren zur förderung von transdermaler elektrotransport-darreichung
DE69509554T2 (de) * 1994-12-06 1999-12-23 Procter & Gamble Lagerbeständige flüssige hautreinigungszusammensetzung mit gelbindenden polymeren, lipiden und athylenglykolfettsäureestern
US5624906A (en) * 1994-12-08 1997-04-29 Lever Brothers Company, Division Of Conopco, Inc. Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds
DE19530879A1 (de) 1995-08-10 1997-02-13 Schuelke & Mayr Gmbh Vorrichtung zum Aufbringen von Medikamentenflüssigkeit auf Schleimhäute in Körperhöhlungen
CN1177594C (zh) * 1996-05-09 2004-12-01 传染病研究股份有限公司 预防治疗粘膜皮肤各种感染 (特别是包括人类免疫缺陷病毒的性传播性疾病 )、炎症、赘生物或其他类型疾病的方法和制剂
US6191165B1 (en) * 1996-05-31 2001-02-20 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
US5908612A (en) * 1996-12-31 1999-06-01 Basf Corporation Oral care compositions comprising liquid polyoxyalkylene compounds as solubilizers/gelling agents
US5843043A (en) 1997-03-25 1998-12-01 Markus; George Syringe and process for dispensing treatment fluid
US5843471A (en) * 1997-11-06 1998-12-01 Chaykin; Sterling Oral cleansing: methods and compositions
BR9815708B1 (pt) * 1998-03-07 2010-10-19 composição tópica para tratar lesões cutáneas.
DE29807045U1 (de) * 1998-04-18 1998-06-25 Jakoubek Medizintechnik Gmbh, 78576 Emmingen-Liptingen Flexible Katheder-Hülsenführung
ATE355050T1 (de) * 1998-04-21 2006-03-15 Infectio Recherche Inc Topische formulierung enthaltend poloxamere und weitere mikrobizide
EP1427404A4 (de) * 2001-08-20 2005-10-26 Maiken Nedergaard Behandlung von glia-tumoren mit glutamat-antagonisten

Also Published As

Publication number Publication date
AU3590499A (en) 1999-11-08
AU762461B2 (en) 2003-06-26
ATE355050T1 (de) 2006-03-15
PL344111A1 (en) 2001-10-08
CN1597008A (zh) 2005-03-23
ID26791A (id) 2001-02-08
CN1302215A (zh) 2001-07-04
EP1769821A1 (de) 2007-04-04
SK15822000A3 (sk) 2001-08-06
US6500460B1 (en) 2002-12-31
EP1079802B1 (de) 2007-02-28
TR200102067T2 (tr) 2002-06-21
RU2224503C2 (ru) 2004-02-27
NZ507609A (en) 2003-09-26
TR200003074T2 (tr) 2001-01-22
CN100374110C (zh) 2008-03-12
WO1999053897A3 (en) 2000-04-13
HUP0101507A3 (en) 2002-10-28
AR018194A1 (es) 2001-10-31
NO20005310D0 (no) 2000-10-20
DE69935325D1 (de) 2007-04-12
ES2284250T3 (es) 2007-11-01
WO1999053897A2 (en) 1999-10-28
DE69935325T2 (de) 2007-11-15
US20030133969A1 (en) 2003-07-17
HK1037861A1 (en) 2002-02-22
BR9909801A (pt) 2002-01-22
JP4665075B2 (ja) 2011-04-06
NO20005310L (no) 2000-12-21
HUP0101507A2 (hu) 2002-03-28
JP2002512180A (ja) 2002-04-23
US7192607B2 (en) 2007-03-20
CN100396344C (zh) 2008-06-25
EP1079802A2 (de) 2001-03-07
KR20010042875A (ko) 2001-05-25

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