IL139139A0 - Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 - Google Patents

Substituted beta-amino acid inhibitors of methionine aminopeptidase-2

Info

Publication number
IL139139A0
IL139139A0 IL13913999A IL13913999A IL139139A0 IL 139139 A0 IL139139 A0 IL 139139A0 IL 13913999 A IL13913999 A IL 13913999A IL 13913999 A IL13913999 A IL 13913999A IL 139139 A0 IL139139 A0 IL 139139A0
Authority
IL
Israel
Prior art keywords
amino acid
methionine aminopeptidase
acid inhibitors
substituted beta
beta
Prior art date
Application number
IL13913999A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Priority claimed from PCT/US1999/009641 external-priority patent/WO1999057098A2/fr
Publication of IL139139A0 publication Critical patent/IL139139A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
IL13913999A 1998-05-01 1999-04-30 Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 IL139139A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7171498A 1998-05-01 1998-05-01
PCT/US1999/009641 WO1999057098A2 (fr) 1998-05-01 1999-04-30 INHIBITEURS β-AMINO-ACIDE SUBSTITUES DE LA METHIONINE AMINOPEPTIDASE-2

Publications (1)

Publication Number Publication Date
IL139139A0 true IL139139A0 (en) 2001-11-25

Family

ID=22103106

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13913999A IL139139A0 (en) 1998-05-01 1999-04-30 Substituted beta-amino acid inhibitors of methionine aminopeptidase-2

Country Status (9)

Country Link
EP (1) EP1073633A2 (fr)
JP (1) JP2002513781A (fr)
KR (1) KR20010043198A (fr)
CN (1) CN1308608A (fr)
AU (1) AU3877899A (fr)
CA (1) CA2329704A1 (fr)
CO (1) CO5021134A1 (fr)
IL (1) IL139139A0 (fr)
PL (1) PL346444A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100357283C (zh) * 2002-04-02 2007-12-26 中国科学院上海药物研究所 一类甲硫氨酰氨肽酶抑制剂
PL376171A1 (en) * 2002-10-09 2005-12-27 Pfizer Products Inc. Thiazole compounds for the treatment of neurodegenerative disorders
JP2006516573A (ja) * 2003-01-31 2006-07-06 メルク　エンド　カムパニー　インコーポレーテッド 糖尿病の治療および予防のためのジペプチジルペプチダーゼ阻害薬としての３−アミノ−４−フェニルブタン酸誘導体
FR2858617A1 (fr) * 2003-08-06 2005-02-11 Inst Nat Sante Rech Med Derives de 4',4'-dithiobis-(3-aminobutane-1-sulfonate-1- sulfonates) nouveaux et compositions les contenant
CN102241678B (zh) * 2011-04-26 2014-10-29 辽宁利锋科技开发有限公司 含有脂环结构化合物的抗肿瘤作用与应用
CN104230935A (zh) * 2011-04-26 2014-12-24 辽宁利锋科技开发有限公司 含有脂环结构化合物的抗肿瘤作用与应用
CN114225045A (zh) * 2016-01-11 2022-03-25 辛德弗雷克斯公司 代谢功能障碍引起的肿瘤的治疗
CN115124449B (zh) * 2022-05-24 2024-02-02 上海英诺富成生物科技有限公司 一种吲哚化合物及制备方法与应用

Also Published As

Publication number Publication date
CO5021134A1 (es) 2001-03-27
AU3877899A (en) 1999-11-23
JP2002513781A (ja) 2002-05-14
EP1073633A2 (fr) 2001-02-07
CN1308608A (zh) 2001-08-15
PL346444A1 (en) 2002-02-11
CA2329704A1 (fr) 1999-11-11
KR20010043198A (ko) 2001-05-25

Similar Documents

Publication Publication Date Title
EE200100086A (et) Hüdroksüpipekolaadi hüdroksaamhappe derivaadid kui MMP inhibiitorid
PL341031A1 (en) Derivatives of hydroxamic acid as inhibitors of matrix metaloprotease (mmp)
PL335027A1 (en) Derivatives of arylsulphonylamino hydroxamic acid
IL134300A0 (en) Aryloxyarylsulfonylamino hydroxamic acid derivatives
PT1070069E (pt) Derivados biciclicos do acido hidroxamico
GB9907263D0 (en) Amino acid derivatives
HUP0001684A3 (en) Use of fumaric acid derivatives
HK1091492A1 (en) Hydantoin derivatives as mmp inhibitors
ZA985205B (en) Novel n-substituted urea inhibitors of arnesyl-protein transferase
GB9401129D0 (en) Hydroxamic acid derivatives as metalloproteinase inhibitors
PL342817A1 (en) Novel derivatives of dihydroxyhexanic acid
IL147216A0 (en) Arylsulfonamido-substituted hydroxamic acid derivatives
IL139884A0 (en) N-substituted derivatives of 5-oximinobarbituric acid
DE59803410D1 (de) Phenolsäureamide hydroxysubstituierter Benzylamine
ITMI981848A0 (it) Tioeteri eterociclici come additivi per lubrificanti
IL139139A0 (en) Substituted beta-amino acid inhibitors of methionine aminopeptidase-2
AU8766498A (en) Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors
NO20005506D0 (no) Substituerte beta-aminosyre-inhibitorer for metionin- aminopeptidase-2
GB9929979D0 (en) Hydroxamic acid derivatives
PL327820A1 (en) Hydroxamic acid based collagenase inhibitors
PL345542A1 (en) Novel salts of n-tert-butylhydroxylamine
PL332450A1 (en) Method of obtaining derivatives of hydroxamic acid
PL345621A1 (en) Α-amino acid phenyl ester derivatives
GB9903488D0 (en) Hydroxamic acid amide derivatives
SI1003720T1 (en) Aryloxyarylsulfonylamino hydroxamic acid derivatives