AU8766498A - Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors - Google Patents

Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors

Info

Publication number
AU8766498A
AU8766498A AU87664/98A AU8766498A AU8766498A AU 8766498 A AU8766498 A AU 8766498A AU 87664/98 A AU87664/98 A AU 87664/98A AU 8766498 A AU8766498 A AU 8766498A AU 8766498 A AU8766498 A AU 8766498A
Authority
AU
Australia
Prior art keywords
hydroxamic acid
fused heterocyclic
acid substituted
metalloproteinase inhibitors
substituted fused
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU87664/98A
Inventor
Conrad Hummel
Chan Kou Hwang
Kevin Koch
Sandra E Russo-Rodriguez
David S Thomson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AU8766498A publication Critical patent/AU8766498A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
AU87664/98A 1997-08-04 1998-08-04 Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors Abandoned AU8766498A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5475397P 1997-08-04 1997-08-04
US60054753 1997-08-04
US12851298A 1998-08-03 1998-08-03
US09128512 1998-08-03
PCT/US1998/016147 WO1999006410A1 (en) 1997-08-04 1998-08-04 Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
AU8766498A true AU8766498A (en) 1999-02-22

Family

ID=26733456

Family Applications (1)

Application Number Title Priority Date Filing Date
AU87664/98A Abandoned AU8766498A (en) 1997-08-04 1998-08-04 Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors

Country Status (5)

Country Link
EP (1) EP1003751A1 (en)
JP (1) JP2003524572A (en)
AU (1) AU8766498A (en)
CA (1) CA2297988A1 (en)
WO (1) WO1999006410A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023443A1 (en) * 1998-10-22 2000-04-27 Akzo Nobel N.V. Tetrahydropyridopyridine derivatives and intermediates for producing the same
FR2795730B1 (en) * 1999-07-01 2001-08-31 Adir NOVEL METALLOPROTEASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP1219607B1 (en) * 1999-09-02 2011-04-06 Shionogi & Co., Ltd. Integrase inhibitors containing aromatic heterocycle derivatives
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
ES2674888T3 (en) 2001-06-26 2018-07-04 Amgen Inc. OPGL antibodies
WO2005009387A2 (en) * 2003-07-23 2005-02-03 X-Ceptor Therapeutics Inc. Azepine derivatives as pharmaceutical agents
DE102004004974A1 (en) * 2004-01-31 2005-08-18 Aventis Pharma Deutschland Gmbh Thieno-imino acid derivatives as inhibitors of matrix metalloproteinases
DE102005002500A1 (en) * 2005-01-19 2006-07-27 Sanofi-Aventis Deutschland Gmbh Tetrahydrofuran derivatives as inhibitors of matrix metalloproteinases
SG121932A1 (en) * 2005-07-27 2006-05-26 Takenaka Corp Mobile building platform
AU2008300827B2 (en) 2007-09-19 2013-04-04 4Sc Ag Novel tetrahydrofusedpyridines as histone deacetylase inhibitors
EA201100187A1 (en) * 2008-07-14 2011-10-31 Новартис Аг SELECTIVE INHIBITORS MMP-12 and MMP-13 BASED ON HYDROXAMIC ACID
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof
AU2019352741A1 (en) 2018-10-04 2021-05-06 Assistance Publique-Hôpitaux De Paris (Aphp) EGFR inhibitors for treating keratodermas
CN113387959B (en) * 2021-06-24 2023-05-05 烟台理工学院 Synthesis method of thieno [3,2-c ] pyridine-6-carboxylic acid methyl ester

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE213232T1 (en) * 1995-11-13 2002-02-15 Hoechst Ag CYCLIC AND HETEROCYCLIC N-SUBSTITUTED ALPHA-IMINOHYDROXAMIC AND CARBOXYLIC ACIDS
FR2748026B1 (en) * 1996-04-26 1998-06-05 Adir NOVEL METALLOPROTEASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
WO1999006410A1 (en) 1999-02-11
JP2003524572A (en) 2003-08-19
CA2297988A1 (en) 1999-02-11
EP1003751A1 (en) 2000-05-31

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase