PL346444A1 - Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 - Google Patents

Substituted beta-amino acid inhibitors of methionine aminopeptidase-2

Info

Publication number
PL346444A1
PL346444A1 PL99346444A PL34644499A PL346444A1 PL 346444 A1 PL346444 A1 PL 346444A1 PL 99346444 A PL99346444 A PL 99346444A PL 34644499 A PL34644499 A PL 34644499A PL 346444 A1 PL346444 A1 PL 346444A1
Authority
PL
Poland
Prior art keywords
amino acid
methionine aminopeptidase
acid inhibitors
substituted beta
beta
Prior art date
Application number
PL99346444A
Inventor
Richard A Craig
Jack Henkin
Megumi Kawai
Linda Lijewski Lynch
Jyoti Patel
George S Sheppard
Jieyi Wang
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Priority claimed from PCT/US1999/009641 external-priority patent/WO1999057098A2/en
Publication of PL346444A1 publication Critical patent/PL346444A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
PL99346444A 1998-05-01 1999-04-30 Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 PL346444A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7171498A 1998-05-01 1998-05-01
PCT/US1999/009641 WO1999057098A2 (en) 1998-05-01 1999-04-30 Substituted beta-amino acid inhibitors of methionine aminopeptidase-2

Publications (1)

Publication Number Publication Date
PL346444A1 true PL346444A1 (en) 2002-02-11

Family

ID=22103106

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99346444A PL346444A1 (en) 1998-05-01 1999-04-30 Substituted beta-amino acid inhibitors of methionine aminopeptidase-2

Country Status (9)

Country Link
EP (1) EP1073633A2 (en)
JP (1) JP2002513781A (en)
KR (1) KR20010043198A (en)
CN (1) CN1308608A (en)
AU (1) AU3877899A (en)
CA (1) CA2329704A1 (en)
CO (1) CO5021134A1 (en)
IL (1) IL139139A0 (en)
PL (1) PL346444A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100357283C (en) * 2002-04-02 2007-12-26 中国科学院上海药物研究所 Methionyl aminopeptidase inhibitor
CN1688557A (en) * 2002-10-09 2005-10-26 辉瑞产品公司 Thiazole compounds for treatment of neurodegenerative disorders
WO2004069162A2 (en) * 2003-01-31 2004-08-19 Merck & Co., Inc. 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
FR2858617A1 (en) * 2003-08-06 2005-02-11 Inst Nat Sante Rech Med NOVEL 4 ', 4'-DITHIOBIS- (3-AMINOBUTANE-1-SULFONATE-1-SULFONATES) DERIVATIVES AND COMPOSITIONS CONTAINING SAME
CN102241678B (en) * 2011-04-26 2014-10-29 辽宁利锋科技开发有限公司 Antitumor effect and application of alicyclic structure-containing compound
CN104230935A (en) * 2011-04-26 2014-12-24 辽宁利锋科技开发有限公司 Anti-tumor effect and application of compound containing alicyclic structure
US10646463B2 (en) * 2016-01-11 2020-05-12 Syndevrx, Inc. Treatment for tumors driven by metabolic dysfunction
CN115124449B (en) * 2022-05-24 2024-02-02 上海英诺富成生物科技有限公司 Indole compound and preparation method and application thereof

Also Published As

Publication number Publication date
IL139139A0 (en) 2001-11-25
JP2002513781A (en) 2002-05-14
CA2329704A1 (en) 1999-11-11
EP1073633A2 (en) 2001-02-07
AU3877899A (en) 1999-11-23
CO5021134A1 (en) 2001-03-27
KR20010043198A (en) 2001-05-25
CN1308608A (en) 2001-08-15

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Legal Events

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