IL139073A0 - Treatment of neuropathy - Google Patents
Treatment of neuropathyInfo
- Publication number
- IL139073A0 IL139073A0 IL13907300A IL13907300A IL139073A0 IL 139073 A0 IL139073 A0 IL 139073A0 IL 13907300 A IL13907300 A IL 13907300A IL 13907300 A IL13907300 A IL 13907300A IL 139073 A0 IL139073 A0 IL 139073A0
- Authority
- IL
- Israel
- Prior art keywords
- neuropathy
- treatment
- pregabalin
- gabapentin
- gmp
- Prior art date
Links
- 201000001119 neuropathy Diseases 0.000 title abstract 2
- 230000007823 neuropathy Effects 0.000 title abstract 2
- 208000033808 peripheral neuropathy Diseases 0.000 title abstract 2
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 abstract 2
- 229940123333 Phosphodiesterase 5 inhibitor Drugs 0.000 abstract 1
- 229960002870 gabapentin Drugs 0.000 abstract 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 abstract 1
- 229960001233 pregabalin Drugs 0.000 abstract 1
- AYXYPKUFHZROOJ-ZETCQYMHSA-N pregabalin Chemical compound CC(C)C[C@H](CN)CC(O)=O AYXYPKUFHZROOJ-ZETCQYMHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15292502A IL152925A0 (en) | 1999-10-21 | 2002-11-18 | Treatment of neuropathy |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9924958.3A GB9924958D0 (en) | 1999-10-21 | 1999-10-21 | Treatment of neuropathy |
GB0021520A GB0021520D0 (en) | 2000-09-01 | 2000-09-01 | Treatment of neuropathy |
Publications (1)
Publication Number | Publication Date |
---|---|
IL139073A0 true IL139073A0 (en) | 2001-11-25 |
Family
ID=26244947
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL152925A IL152925A (en) | 1999-10-21 | 2000-10-16 | Pharmaceutical preparations for the treatment of neurological disease containing an inhibitor of ring guanizine '3', 5 '- monophosphate phosphodiesterase 5 and one of gabapentin or pregabalin |
IL13907300A IL139073A0 (en) | 1999-10-21 | 2000-10-16 | Treatment of neuropathy |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL152925A IL152925A (en) | 1999-10-21 | 2000-10-16 | Pharmaceutical preparations for the treatment of neurological disease containing an inhibitor of ring guanizine '3', 5 '- monophosphate phosphodiesterase 5 and one of gabapentin or pregabalin |
Country Status (16)
Country | Link |
---|---|
US (2) | US20030162782A1 (de) |
EP (2) | EP1129706A3 (de) |
JP (2) | JP2001122803A (de) |
KR (1) | KR20010051181A (de) |
AT (1) | ATE380049T1 (de) |
AU (1) | AU781550B2 (de) |
CA (1) | CA2323839C (de) |
CO (1) | CO5271711A1 (de) |
CY (1) | CY1107285T1 (de) |
DE (1) | DE60037347T2 (de) |
DK (1) | DK1440709T3 (de) |
ES (1) | ES2295726T3 (de) |
HU (1) | HUP0004120A3 (de) |
IL (2) | IL152925A (de) |
PE (1) | PE20010754A1 (de) |
PT (1) | PT1440709E (de) |
Families Citing this family (73)
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DE10135815A1 (de) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
KR20040066788A (ko) | 2001-08-31 | 2004-07-27 | 더 락커펠러 유니버시티 | 프스포다이에스터레이즈 활성 및 뇌에서프스포다이에스터레이즈 1b 매개되는 신호의 조절 |
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US20050143388A1 (en) * | 2002-01-04 | 2005-06-30 | Michael Chopp | Nitric oxide donors for treatment of disease and injury |
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DE10325813B4 (de) * | 2003-06-06 | 2007-12-20 | Universitätsklinikum Freiburg | Prophylaxe und/oder Therapie bei der portalen Hypertonie |
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US20080194592A1 (en) * | 2005-08-23 | 2008-08-14 | Intra-Cellular Therapies, Inc. | Organic Compounds |
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ES2732442T3 (es) | 2014-06-20 | 2019-11-22 | Intra Cellular Therapies Inc | Compuestos orgánicos |
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US10285992B2 (en) | 2014-08-07 | 2019-05-14 | Intra-Cellular Therapies, Inc. | Combinations of PDE1 inhibitors and NEP inhibitors and associated methods |
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US10813894B2 (en) | 2015-02-20 | 2020-10-27 | The Regents Of The University Of California | Methods of inhibiting pain |
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-
2000
- 2000-10-16 IL IL152925A patent/IL152925A/en not_active IP Right Cessation
- 2000-10-16 IL IL13907300A patent/IL139073A0/xx unknown
- 2000-10-17 PT PT04010436T patent/PT1440709E/pt unknown
- 2000-10-17 AT AT04010436T patent/ATE380049T1/de not_active IP Right Cessation
- 2000-10-17 EP EP00309129A patent/EP1129706A3/de not_active Withdrawn
- 2000-10-17 DK DK04010436T patent/DK1440709T3/da active
- 2000-10-17 DE DE60037347T patent/DE60037347T2/de not_active Expired - Fee Related
- 2000-10-17 ES ES04010436T patent/ES2295726T3/es not_active Expired - Lifetime
- 2000-10-17 EP EP04010436A patent/EP1440709B1/de not_active Expired - Lifetime
- 2000-10-19 CA CA002323839A patent/CA2323839C/en not_active Expired - Fee Related
- 2000-10-20 AU AU66650/00A patent/AU781550B2/en not_active Withdrawn - After Issue
- 2000-10-20 HU HU0004120A patent/HUP0004120A3/hu unknown
- 2000-10-20 CO CO00080163A patent/CO5271711A1/es not_active Application Discontinuation
- 2000-10-20 PE PE2000001133A patent/PE20010754A1/es not_active Application Discontinuation
- 2000-10-21 KR KR1020000062129A patent/KR20010051181A/ko not_active Application Discontinuation
- 2000-10-23 JP JP2000322510A patent/JP2001122803A/ja active Pending
-
2002
- 2002-07-26 US US10/206,615 patent/US20030162782A1/en not_active Abandoned
- 2002-10-10 JP JP2002297617A patent/JP2003119131A/ja active Pending
-
2003
- 2003-12-10 US US10/731,905 patent/US20040122010A1/en not_active Abandoned
-
2008
- 2008-02-18 CY CY20081100193T patent/CY1107285T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT1440709E (pt) | 2008-02-06 |
US20030162782A1 (en) | 2003-08-28 |
DE60037347T2 (de) | 2008-11-27 |
PE20010754A1 (es) | 2001-07-18 |
EP1440709B1 (de) | 2007-12-05 |
JP2003119131A (ja) | 2003-04-23 |
ATE380049T1 (de) | 2007-12-15 |
AU6665000A (en) | 2001-04-26 |
CA2323839A1 (en) | 2001-04-21 |
DK1440709T3 (da) | 2008-03-17 |
JP2001122803A (ja) | 2001-05-08 |
EP1440709A2 (de) | 2004-07-28 |
HUP0004120A2 (hu) | 2002-11-28 |
US20040122010A1 (en) | 2004-06-24 |
IL152925A (en) | 2010-04-15 |
ES2295726T3 (es) | 2008-04-16 |
CA2323839C (en) | 2008-03-18 |
EP1129706A2 (de) | 2001-09-05 |
EP1129706A3 (de) | 2002-01-02 |
CO5271711A1 (es) | 2003-04-30 |
CY1107285T1 (el) | 2012-11-21 |
EP1440709A3 (de) | 2004-12-08 |
DE60037347D1 (de) | 2008-01-17 |
HU0004120D0 (de) | 2001-01-29 |
AU781550B2 (en) | 2005-05-26 |
HUP0004120A3 (en) | 2003-11-28 |
KR20010051181A (ko) | 2001-06-25 |
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