IL137953A0 - Phthalimido arylpiperazines as alpha 1a receptor antagonists useful in the treatment of benign prostatic hyperplasia - Google Patents
Phthalimido arylpiperazines as alpha 1a receptor antagonists useful in the treatment of benign prostatic hyperplasiaInfo
- Publication number
- IL137953A0 IL137953A0 IL13795399A IL13795399A IL137953A0 IL 137953 A0 IL137953 A0 IL 137953A0 IL 13795399 A IL13795399 A IL 13795399A IL 13795399 A IL13795399 A IL 13795399A IL 137953 A0 IL137953 A0 IL 137953A0
- Authority
- IL
- Israel
- Prior art keywords
- alpha
- treatment
- receptor antagonists
- benign prostatic
- prostatic hyperplasia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7551098P | 1998-02-20 | 1998-02-20 | |
| PCT/US1999/003694 WO1999042445A1 (en) | 1998-02-20 | 1999-02-19 | Phtalimido arylpiperazines as alpha 1a receptor antagonists useful in the treatment of benign prostatic hyperplasia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137953A0 true IL137953A0 (en) | 2001-10-31 |
Family
ID=22126243
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13795399A IL137953A0 (en) | 1998-02-20 | 1999-02-19 | Phthalimido arylpiperazines as alpha 1a receptor antagonists useful in the treatment of benign prostatic hyperplasia |
| IL137953A IL137953A (en) | 1998-02-20 | 2000-08-18 | Phthalimido arylpiperazines, pharmaceutical compositions containing them and their use in the preparation of medicaments for treating benign prostatic hyperplasia |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL137953A IL137953A (en) | 1998-02-20 | 2000-08-18 | Phthalimido arylpiperazines, pharmaceutical compositions containing them and their use in the preparation of medicaments for treating benign prostatic hyperplasia |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20020077476A1 (pl) |
| EP (1) | EP1056720B1 (pl) |
| JP (1) | JP2002503722A (pl) |
| KR (1) | KR100608473B1 (pl) |
| CN (1) | CN1172911C (pl) |
| AR (1) | AR015521A1 (pl) |
| AT (1) | ATE280156T1 (pl) |
| AU (1) | AU766411B2 (pl) |
| BR (1) | BR9908122A (pl) |
| DE (1) | DE69921300T2 (pl) |
| ES (1) | ES2233023T3 (pl) |
| HK (1) | HK1031872A1 (pl) |
| HU (1) | HUP0100704A3 (pl) |
| IL (2) | IL137953A0 (pl) |
| NO (1) | NO317104B1 (pl) |
| NZ (1) | NZ506461A (pl) |
| PL (1) | PL194649B1 (pl) |
| PT (1) | PT1056720E (pl) |
| TR (1) | TR200003224T2 (pl) |
| WO (1) | WO1999042445A1 (pl) |
| ZA (1) | ZA991319B (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20010164A1 (it) * | 2001-01-30 | 2002-07-30 | Recordati Chem Pharm | Alfa 1 antagonisti selettivi a + d |
| CN103387531A (zh) * | 2012-05-10 | 2013-11-13 | 广州医学院 | 酰胺类芳基哌嗪衍生物及其制备方法和在抗良性前列腺增生中的应用 |
| HUP1400294A2 (hu) | 2014-06-13 | 2015-12-28 | Skillpharm Kft | Clopidogrel új alkalmazása |
| CN105061434B (zh) * | 2015-07-30 | 2017-07-21 | 新发药业有限公司 | 一种西他列汀磷酸盐的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1382742A (en) | 1972-09-19 | 1975-02-05 | Labaz | Benzofuran derivatives and process for preparing the same |
| CH585693A5 (pl) | 1974-02-08 | 1977-03-15 | Ciba Geigy Ag | |
| HU177702B (en) | 1977-10-24 | 1981-12-28 | Noevenyvedelmi Kutato Intezet | Plant growth regulator and process for preparing the active materials |
| PT82077B (fr) * | 1985-02-26 | 1987-09-25 | Sanofi Sa | Procede pour l'obtention des derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides |
| FR2678271B1 (fr) * | 1991-06-27 | 1995-01-13 | Synthelabo | Derives de pyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
| US5428037A (en) * | 1993-04-09 | 1995-06-27 | Syntex Pharmaceuticals, Ltd. | Heterocyclic derivatives in the treatment of Ischaemia and related diseases |
| EA001904B1 (ru) * | 1997-05-12 | 2001-10-22 | ОРТО МакНЕЙЛ ФАРМАСЬЮТИКАЛ, ИНК. | Арилзамещенные пиперазины для лечения доброкачественной гиперплазии простаты |
-
1999
- 1999-02-18 ZA ZA9901319A patent/ZA991319B/xx unknown
- 1999-02-19 KR KR1020007009159A patent/KR100608473B1/ko not_active IP Right Cessation
- 1999-02-19 WO PCT/US1999/003694 patent/WO1999042445A1/en active IP Right Grant
- 1999-02-19 PT PT99908303T patent/PT1056720E/pt unknown
- 1999-02-19 EP EP99908303A patent/EP1056720B1/en not_active Expired - Lifetime
- 1999-02-19 IL IL13795399A patent/IL137953A0/xx active IP Right Grant
- 1999-02-19 TR TR2000/03224T patent/TR200003224T2/xx unknown
- 1999-02-19 DE DE69921300T patent/DE69921300T2/de not_active Expired - Fee Related
- 1999-02-19 NZ NZ506461A patent/NZ506461A/en unknown
- 1999-02-19 PL PL99342357A patent/PL194649B1/pl not_active IP Right Cessation
- 1999-02-19 ES ES99908303T patent/ES2233023T3/es not_active Expired - Lifetime
- 1999-02-19 CN CNB998030260A patent/CN1172911C/zh not_active Expired - Fee Related
- 1999-02-19 AT AT99908303T patent/ATE280156T1/de not_active IP Right Cessation
- 1999-02-19 HU HU0100704A patent/HUP0100704A3/hu unknown
- 1999-02-19 JP JP2000532397A patent/JP2002503722A/ja not_active Withdrawn
- 1999-02-19 AU AU27765/99A patent/AU766411B2/en not_active Ceased
- 1999-02-19 BR BR9908122-9A patent/BR9908122A/pt not_active Application Discontinuation
- 1999-02-23 AR ARP990100676A patent/AR015521A1/es active IP Right Grant
-
2000
- 2000-08-18 IL IL137953A patent/IL137953A/en not_active IP Right Cessation
- 2000-08-18 NO NO20004142A patent/NO317104B1/no not_active IP Right Cessation
-
2001
- 2001-04-03 HK HK01102397A patent/HK1031872A1/xx not_active IP Right Cessation
- 2001-12-11 US US10/014,979 patent/US20020077476A1/en not_active Abandoned
-
2002
- 2002-07-29 US US10/207,473 patent/US6780994B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0100704A3 (en) | 2002-10-28 |
| HK1031872A1 (en) | 2001-06-29 |
| AU766411B2 (en) | 2003-10-16 |
| BR9908122A (pt) | 2001-11-13 |
| EP1056720B1 (en) | 2004-10-20 |
| CN1172911C (zh) | 2004-10-27 |
| JP2002503722A (ja) | 2002-02-05 |
| ZA991319B (en) | 2000-11-20 |
| DE69921300D1 (de) | 2004-11-25 |
| CN1291185A (zh) | 2001-04-11 |
| ATE280156T1 (de) | 2004-11-15 |
| KR100608473B1 (ko) | 2006-08-09 |
| PL342357A1 (en) | 2001-06-04 |
| PL194649B1 (pl) | 2007-06-29 |
| US20020077476A1 (en) | 2002-06-20 |
| KR20010041118A (ko) | 2001-05-15 |
| US20030088099A1 (en) | 2003-05-08 |
| WO1999042445A1 (en) | 1999-08-26 |
| NZ506461A (en) | 2003-08-29 |
| ES2233023T3 (es) | 2005-06-01 |
| EP1056720A1 (en) | 2000-12-06 |
| PT1056720E (pt) | 2005-02-28 |
| AU2776599A (en) | 1999-09-06 |
| NO317104B1 (no) | 2004-08-09 |
| NO20004142L (no) | 2000-10-19 |
| HUP0100704A2 (hu) | 2001-10-28 |
| TR200003224T2 (tr) | 2001-03-21 |
| NO20004142D0 (no) | 2000-08-18 |
| US6780994B2 (en) | 2004-08-24 |
| IL137953A (en) | 2006-12-31 |
| DE69921300T2 (de) | 2006-03-09 |
| AR015521A1 (es) | 2001-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |