IL137831A0 - Immunological methods to modulate myostatin in vertebrate subjects - Google Patents
Immunological methods to modulate myostatin in vertebrate subjectsInfo
- Publication number
- IL137831A0 IL137831A0 IL13783199A IL13783199A IL137831A0 IL 137831 A0 IL137831 A0 IL 137831A0 IL 13783199 A IL13783199 A IL 13783199A IL 13783199 A IL13783199 A IL 13783199A IL 137831 A0 IL137831 A0 IL 137831A0
- Authority
- IL
- Israel
- Prior art keywords
- immunological methods
- vertebrate subjects
- modulate myostatin
- myostatin
- modulate
- Prior art date
Links
- 102000004472 Myostatin Human genes 0.000 title 1
- 108010056852 Myostatin Proteins 0.000 title 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 title 1
- 230000001900 immune effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7521398P | 1998-02-19 | 1998-02-19 | |
PCT/CA1999/000128 WO1999042573A1 (en) | 1998-02-19 | 1999-02-19 | Immunological methods to modulate myostatin in vertebrate subjects |
Publications (1)
Publication Number | Publication Date |
---|---|
IL137831A0 true IL137831A0 (en) | 2001-10-31 |
Family
ID=22124285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13783199A IL137831A0 (en) | 1998-02-19 | 1999-02-19 | Immunological methods to modulate myostatin in vertebrate subjects |
Country Status (18)
Country | Link |
---|---|
US (2) | US6369201B1 (de) |
EP (3) | EP2018871B1 (de) |
JP (1) | JP2002504326A (de) |
KR (1) | KR20010041111A (de) |
AR (1) | AR019818A1 (de) |
AT (2) | ATE419353T1 (de) |
AU (1) | AU765014B2 (de) |
BR (1) | BR9907995A (de) |
CA (2) | CA2323607C (de) |
CY (2) | CY1108074T1 (de) |
DE (2) | DE69934970T2 (de) |
DK (2) | DK1056845T3 (de) |
ES (3) | ES2280115T3 (de) |
IL (1) | IL137831A0 (de) |
NZ (1) | NZ506911A (de) |
PT (2) | PT1770162E (de) |
WO (1) | WO1999042573A1 (de) |
ZA (1) | ZA991369B (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
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US6465239B1 (en) * | 1993-03-19 | 2002-10-15 | The John Hopkins University School Of Medicine | Growth differentiation factor-8 nucleic acid and polypeptides from aquatic species and non-human transgenic aquatic species |
CA2157577C (en) | 1993-03-19 | 2009-11-17 | Se-Jin Lee | Growth differentiation factor-8 |
US7393682B1 (en) * | 1993-03-19 | 2008-07-01 | The Johns Hopkins University School Of Medicine | Polynucleotides encoding promyostatin polypeptides |
US7566768B1 (en) * | 1995-10-26 | 2009-07-28 | The Johns Hopkins University School Of Medicine | Promyostatin peptides and methods of using same |
US5994618A (en) * | 1997-02-05 | 1999-11-30 | Johns Hopkins University School Of Medicine | Growth differentiation factor-8 transgenic mice |
US7332575B2 (en) | 1994-03-18 | 2008-02-19 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-8 nucleic acid and polypeptide from aquatic species, and transgenic aquatic species |
BR0008188A (pt) * | 1999-01-21 | 2002-02-13 | Metamorphix Inc | Inibidores de fator de diferenciação de crescimento e usos para os mesmos |
CN1384757A (zh) * | 1999-07-20 | 2002-12-11 | 法麦克萨有限公司 | 下调gdf-8活性的方法 |
EP1072680A1 (de) | 1999-07-30 | 2001-01-31 | Pfizer Products Inc. | Regulatorische Region von Myostatin |
AU782925B2 (en) | 2000-01-18 | 2005-09-08 | Orico Limited | Myostatin and mimetics thereof |
US7037501B2 (en) * | 2001-01-04 | 2006-05-02 | Regents Of The University Of Minnesota | Myostatin immnoconjugate |
TWI329129B (en) * | 2001-02-08 | 2010-08-21 | Wyeth Corp | Modified and stabilized gdf propeptides and uses thereof |
US7320789B2 (en) | 2001-09-26 | 2008-01-22 | Wyeth | Antibody inhibitors of GDF-8 and uses thereof |
AU2003217612A1 (en) * | 2002-02-21 | 2003-09-09 | Wyeth | GASP1: a follistatin domain containing protein |
PL374966A1 (en) * | 2002-02-21 | 2005-11-14 | Wyeth | Follistatin domain containing proteins |
CA2496213C (en) * | 2002-09-16 | 2013-11-19 | The Johns Hopkins University | Metalloprotease activation of myostatin, and methods of modulating myostatin activity |
AR047392A1 (es) | 2002-10-22 | 2006-01-18 | Wyeth Corp | Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines |
US20040223966A1 (en) * | 2002-10-25 | 2004-11-11 | Wolfman Neil M. | ActRIIB fusion polypeptides and uses therefor |
MXPA05006521A (es) * | 2002-12-20 | 2005-08-26 | Amgen Inc | Agentes de enlace que inhiben miostatina. |
KR20060026860A (ko) * | 2003-06-02 | 2006-03-24 | 와이어쓰 | 신경근 장애의 치료를 위한, 코르티코스테로이드와 조합된미오스타틴 (gdf8) 저해제의 용도 |
AU2004312411B8 (en) * | 2003-12-31 | 2011-11-24 | Schering-Plough Pty. Limited | Neutralizing epitope-based growth enhancing vaccine |
JP4688483B2 (ja) | 2004-04-15 | 2011-05-25 | 株式会社テクノネットワーク四国 | フォリスタチン変異体ポリペプチド |
CA2575563A1 (en) * | 2004-08-12 | 2006-02-23 | Wyeth | Combination therapy for diabetes, obesity, and cardiovascular diseases using gdf-8 inhibitors |
ATE552272T1 (de) | 2004-09-30 | 2012-04-15 | Orico Ltd | Myostatin-isoform |
EP1831372A2 (de) * | 2004-12-30 | 2007-09-12 | Schering-Plough Ltd. | Neutralisierendes-epitop-basierendener impfstoff, der wachstum fordert |
NZ538097A (en) * | 2005-02-07 | 2006-07-28 | Ovita Ltd | Method and compositions for improving wound healing |
EP1864139A2 (de) * | 2005-03-23 | 2007-12-12 | Wyeth | Nachweis einer immunreaktion auf gdf-8-modulierende wirkstoffe |
CA2632544C (en) * | 2005-12-06 | 2014-09-23 | Amgen Inc. | Use of myostatin antagonist for treating the effects of hypogonadism |
AU2013231037B2 (en) * | 2006-08-03 | 2016-05-12 | Myostin Therapeutics Pty Ltd | Myostatin antagonists |
EP2054434B1 (de) * | 2006-08-03 | 2017-03-15 | Myostin Therapeutics Pty Ltd | Myostatin-antagonisten |
SI2066695T1 (sl) | 2006-09-05 | 2013-05-31 | Eli Lilly And Company | Protitelo proti miostatinu |
JP2010535708A (ja) | 2007-08-03 | 2010-11-25 | ビオマリン アイジーエー リミテッド | デュシェンヌ型筋ジストロフィーの治療のための薬物併用 |
GB0715087D0 (en) | 2007-08-03 | 2007-09-12 | Summit Corp Plc | Drug combinations for the treatment of duchenne muscular dystrophy |
KR100857861B1 (ko) * | 2007-10-15 | 2008-09-11 | 주식회사 바이오리더스 | Myo-2 펩타이드 중합체와 마이오스타틴의 융합단백질표면발현용 벡터 및 상기 벡터로 형질전환된 미생물 |
SI2880053T1 (sl) | 2012-08-01 | 2020-08-31 | Ikaika Therapeutics, Llc | Blažitev poškodbe tkiva in fibroze s protitelesom proti-LTBP4 |
CN104391628B (zh) * | 2014-04-02 | 2018-02-23 | 贵阳朗玛信息技术股份有限公司 | 进程切换方法及装置 |
EP2960653A1 (de) * | 2014-06-24 | 2015-12-30 | Stichting Kwaliteitsgarantie Vleeskalversector | Diagnosekit und Verfahren zur Identifizierung der Manipulation der Muskelmasse bei einem Haustier |
CN113347990A (zh) | 2018-12-21 | 2021-09-03 | 西北大学 | 膜联蛋白在预防和治疗肌膜损伤中的用途 |
WO2020139977A1 (en) | 2018-12-26 | 2020-07-02 | Northwestern University | Use of glucocorticoid steroids in preventing and treating conditions of muscle wasting, aging and metabolic disorder |
CA3131959A1 (en) * | 2019-03-01 | 2020-09-10 | Knc Laboratories Co., Ltd. | Inhibition of myostatin signal by myostatin splice variant-derived protein and utilization thereof |
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US1605763A (en) | 1926-11-02 | Garment retainer | ||
US2754818A (en) | 1950-06-24 | 1956-07-17 | Scherer Corp R P | Hypo jet injector |
US3330276A (en) | 1963-10-07 | 1967-07-11 | Scherer Corp R P | Hypodermic jet injector |
US3788315A (en) | 1971-04-20 | 1974-01-29 | S Laurens | Disposable cutaneous transjector |
US3853125A (en) | 1971-10-05 | 1974-12-10 | W Clark | Disposable needleless injector |
US4491632A (en) | 1979-10-22 | 1985-01-01 | The Massachusetts General Hospital | Process for producing antibodies to hepatitis virus and cell lines therefor |
US4310550A (en) | 1979-10-26 | 1982-01-12 | Pfizer Inc. | Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants |
US4425437A (en) | 1979-11-05 | 1984-01-10 | Genentech, Inc. | Microbial polypeptide expression vehicle |
US4431739A (en) | 1979-11-05 | 1984-02-14 | Genentech, Inc. | Transformant bacterial culture capable of expressing heterologous protein |
US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
US4338397A (en) | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
DE3167442D1 (en) | 1980-07-07 | 1985-01-10 | Nat Res Dev | Improvements in or relating to cell lines |
US4341761A (en) | 1980-07-25 | 1982-07-27 | E. I. Du Pont De Nemours And Company | Antibodies to immunogenic peptides and their use to purify human fibroblast interferon |
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JPS5873993U (ja) | 1981-11-12 | 1983-05-19 | 三菱電機株式会社 | 2気筒回転式圧縮機 |
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US5374426A (en) | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
US5055400A (en) | 1986-11-26 | 1991-10-08 | University Of Guelph | Leukotoxin gene of pasteurella haemolytica |
US4957739A (en) | 1987-08-13 | 1990-09-18 | Board Of Regents, The University Of Texas System | Pharmaceutical compositions of a 105 kD P. Haemolytica derived antigen useful for treatment of Shipping Fever |
US5151267A (en) | 1988-07-15 | 1992-09-29 | University Of Saskatchewan | Bovine herpesvirus type 1 polypeptides and vaccines |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
CA2014033C (en) | 1989-04-07 | 1993-02-09 | Stephen D. Acres | Compositions and treatments for pneumonia in animals |
US5062830A (en) | 1990-04-04 | 1991-11-05 | Derata Corporation | Dry disposable nozzle assembly for medical jet injector |
US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
US5149655A (en) | 1990-06-21 | 1992-09-22 | Agracetus, Inc. | Apparatus for genetic transformation |
US5837268A (en) | 1991-10-16 | 1998-11-17 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
US5994618A (en) | 1997-02-05 | 1999-11-30 | Johns Hopkins University School Of Medicine | Growth differentiation factor-8 transgenic mice |
CA2157577C (en) | 1993-03-19 | 2009-11-17 | Se-Jin Lee | Growth differentiation factor-8 |
CA2194660C (en) | 1994-07-08 | 2009-09-29 | Se-Jin Lee | Growth differentiation factor-11 |
WO1998033887A1 (en) | 1997-02-05 | 1998-08-06 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-8 |
PT2045322E (pt) | 1997-07-14 | 2015-10-16 | Université de Liège | Musculatura dupla em mamíferos |
AU8666398A (en) | 1997-08-01 | 1999-02-22 | Johns Hopkins University School Of Medicine, The | Methods to identify growth differentiation factor (gdf) receptors |
WO1999024618A1 (en) | 1997-11-10 | 1999-05-20 | The Johns Hopkins University School Of Medicine | Methods for detection of mutations in myostatin variants |
CA2319703C (en) | 1998-02-05 | 2005-09-20 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-8 |
CN1384757A (zh) | 1999-07-20 | 2002-12-11 | 法麦克萨有限公司 | 下调gdf-8活性的方法 |
-
1999
- 1999-02-18 US US09/252,149 patent/US6369201B1/en not_active Expired - Lifetime
- 1999-02-19 CA CA002323607A patent/CA2323607C/en not_active Expired - Fee Related
- 1999-02-19 NZ NZ506911A patent/NZ506911A/en not_active IP Right Cessation
- 1999-02-19 PT PT06026306T patent/PT1770162E/pt unknown
- 1999-02-19 ES ES99904660T patent/ES2280115T3/es not_active Expired - Lifetime
- 1999-02-19 AT AT06026306T patent/ATE419353T1/de active
- 1999-02-19 DK DK99904660T patent/DK1056845T3/da active
- 1999-02-19 ES ES08018446.8T patent/ES2527410T3/es not_active Expired - Lifetime
- 1999-02-19 DE DE69934970T patent/DE69934970T2/de not_active Expired - Lifetime
- 1999-02-19 CA CA2687533A patent/CA2687533C/en not_active Expired - Lifetime
- 1999-02-19 IL IL13783199A patent/IL137831A0/xx unknown
- 1999-02-19 DE DE69940230T patent/DE69940230D1/de not_active Expired - Lifetime
- 1999-02-19 EP EP08018446.8A patent/EP2018871B1/de not_active Expired - Lifetime
- 1999-02-19 PT PT99904660T patent/PT1056845E/pt unknown
- 1999-02-19 BR BR9907995-0A patent/BR9907995A/pt active Search and Examination
- 1999-02-19 EP EP99904660A patent/EP1056845B1/de not_active Expired - Lifetime
- 1999-02-19 DK DK06026306T patent/DK1770162T3/da active
- 1999-02-19 EP EP06026306A patent/EP1770162B1/de not_active Expired - Lifetime
- 1999-02-19 AU AU25073/99A patent/AU765014B2/en not_active Ceased
- 1999-02-19 KR KR1020007009152A patent/KR20010041111A/ko not_active Application Discontinuation
- 1999-02-19 ZA ZA9901369A patent/ZA991369B/xx unknown
- 1999-02-19 AT AT99904660T patent/ATE352619T1/de active
- 1999-02-19 ES ES06026306T patent/ES2318654T3/es not_active Expired - Lifetime
- 1999-02-19 JP JP2000532513A patent/JP2002504326A/ja active Pending
- 1999-02-19 WO PCT/CA1999/000128 patent/WO1999042573A1/en active IP Right Grant
- 1999-02-23 AR ARP990100671A patent/AR019818A1/es active IP Right Grant
-
2002
- 2002-02-11 US US10/074,152 patent/US20030065137A1/en not_active Abandoned
-
2007
- 2007-04-23 CY CY20071100550T patent/CY1108074T1/el unknown
-
2009
- 2009-03-18 CY CY20091100304T patent/CY1108889T1/el unknown
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