IL137007A0 - Compounds with growth hormone releasing properties - Google Patents
Compounds with growth hormone releasing propertiesInfo
- Publication number
- IL137007A0 IL137007A0 IL13700799A IL13700799A IL137007A0 IL 137007 A0 IL137007 A0 IL 137007A0 IL 13700799 A IL13700799 A IL 13700799A IL 13700799 A IL13700799 A IL 13700799A IL 137007 A0 IL137007 A0 IL 137007A0
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- growth hormone
- hormone releasing
- releasing properties
- properties
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK5698 | 1998-01-16 | ||
| DK79998 | 1998-06-15 | ||
| PCT/DK1999/000021 WO1999036431A1 (en) | 1998-01-16 | 1999-01-15 | Compounds with growth hormone releasing properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137007A0 true IL137007A0 (en) | 2001-06-14 |
Family
ID=26063207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13700799A IL137007A0 (en) | 1998-01-16 | 1999-01-15 | Compounds with growth hormone releasing properties |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP1506969B1 (xx) |
| JP (1) | JP4382279B2 (xx) |
| KR (1) | KR20010034198A (xx) |
| CN (1) | CN1288467A (xx) |
| AT (2) | ATE470671T1 (xx) |
| AU (1) | AU766305B2 (xx) |
| BR (1) | BR9906975A (xx) |
| CA (1) | CA2318558A1 (xx) |
| DE (1) | DE69921611T2 (xx) |
| HU (1) | HUP0100777A3 (xx) |
| IL (1) | IL137007A0 (xx) |
| NO (1) | NO20003629L (xx) |
| PL (1) | PL341707A1 (xx) |
| TW (1) | TW589325B (xx) |
| WO (1) | WO1999036431A1 (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020111461A1 (en) | 1999-05-21 | 2002-08-15 | Todd C. Somers | Low molecular weight peptidomimetic growth hormone secretagogues |
| UA73530C2 (uk) | 1999-11-10 | 2005-08-15 | Ново Нордіск А/С | Сполука з властивостями вивільнювати гормон росту |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| JP5122950B2 (ja) * | 2004-06-29 | 2013-01-16 | ヘルシン セラピューティクス（ユー．エス．），インコーポレイティド | （３ｒ）−１−（２−メチルアラニル−ｄ−トリプトフィル）−３−（フェニルメチル）−３−ピペリジンカルボン酸１，２，２−トリメチルヒドラジドの結晶形 |
| CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
| BRPI0807046A2 (pt) | 2007-02-09 | 2015-05-26 | Tranzyme Pharma Inc | Composto, composição farmacêutica, métodos de tratar um distúrbio, uma doença cardiovascular e um paciente que sofre de motilidade gastrointestinal reduzida ou disfuncional e, kit. |
| CN108129357B (zh) * | 2016-12-01 | 2021-12-21 | 上海医药工业研究院 | 阿拉莫林中间体的制备方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8005121A (nl) * | 1979-09-20 | 1981-03-24 | Erba Farmitalia | Biologisch actieve peptiden. |
| WO1983002272A1 (en) | 1981-12-28 | 1983-07-07 | Beckman Instruments Inc | Synthetic peptides having pituitary growth hormone releasing activity |
| US4839344A (en) | 1987-06-12 | 1989-06-13 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| AU633003B2 (en) | 1988-05-11 | 1993-01-21 | Polygen Holding Corporation | Polypeptide compounds having growth hormone releasing activity |
| IT1240643B (it) | 1990-05-11 | 1993-12-17 | Mediolanum Farmaceutici Spa | Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano |
| IL98910A0 (en) | 1990-07-24 | 1992-07-15 | Polygen Holding Corp | Polypeptide compounds having growth hormone releasing activity and pharmaceutical compositions containing them |
| US5663146A (en) | 1991-08-22 | 1997-09-02 | Administrators Of The Tulane Educational Fund | Polypeptide analogues having growth hormone releasing activity |
| US5578593A (en) | 1992-12-11 | 1996-11-26 | Merck & Co., Inc. | Spiro piperidines and homologs promote release of growth hormone |
| WO1995014666A1 (en) | 1993-11-24 | 1995-06-01 | Merck & Co., Inc. | Indolyl group containing compounds and the use thereof to promote the release of growth hormone(s) |
| WO1995017423A1 (en) | 1993-12-23 | 1995-06-29 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| CA2179598A1 (en) | 1993-12-23 | 1995-06-29 | Nils Langeland Johansen | Compounds with growth hormone releasing properties |
| WO1995034311A1 (en) | 1994-06-13 | 1995-12-21 | Merck & Co., Inc. | Piperazine compounds promote release of growth hormone |
| WO1996002530A1 (en) | 1994-07-20 | 1996-02-01 | Merck & Co., Inc. | Piperidines and hexahydro-1h-azepines spiro substituted at the 4-position promote release of growth hormone |
| US5767118A (en) | 1994-10-26 | 1998-06-16 | Merck & Co., Inc. | 4-Heterocyclic peperidines promote release of growth hormone |
| US5798337A (en) | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
| IL116923A (en) | 1995-01-27 | 2000-09-28 | Novo Nordisk As | Compounds with growth hormone releasing properties and pharmaceutical compositions containing them |
| US5559128A (en) | 1995-04-18 | 1996-09-24 | Merck & Co., Inc. | 3-substituted piperidines promote release of growth hormone |
| WO1996035713A1 (en) | 1995-05-08 | 1996-11-14 | Pfizer, Inc. | Dipeptides which promote release of growth hormone |
| DE69533991T2 (de) | 1995-05-29 | 2006-04-13 | Pfizer Inc. | Dipeptide, die die ausschüttung von wachstumshormonen stimulieren |
| HUP9802821A3 (en) | 1995-06-22 | 2000-03-28 | Novo Nordisk As | Compounds with growth hormone releasing properties |
| AU6772996A (en) | 1995-08-21 | 1997-03-12 | Eli Lilly And Company | 2-acylaminopropanamides as growth hormone secretagogues |
| WO1997007117A1 (en) | 1995-08-21 | 1997-02-27 | Eli Lilly And Company | 2-acylaminopropanamines as growth hormone secretagogues |
| EP0766966A3 (en) | 1995-09-08 | 2001-02-28 | Eli Lilly And Company | Method of treating insulin resistance |
| AU7169696A (en) | 1995-09-26 | 1997-04-17 | Merck & Co., Inc. | 3-spirolactam, 3-spiroamino, 3-spirolactone and 3-spirobenzopyran piperidines and pyrrolidines promote release of growth hormone |
| IT1277113B1 (it) | 1995-12-20 | 1997-11-04 | Romano Deghenghi | Composti oligopeptidici contenenti d-2-alchiltriptofano in grado di promuovere la liberazione dell'ormone della crescita |
| PL327227A1 (en) * | 1995-12-22 | 1998-12-07 | Novo Nordisk As | Compounds exhibiting growth hormone liberating properties |
| TW432073B (en) | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| AU2334097A (en) | 1996-03-21 | 1997-10-10 | Merck & Co., Inc. | 4-spiroindoline piperidines promote release of growth hormone |
| AU7906998A (en) * | 1997-06-20 | 1999-01-04 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
-
1999
- 1999-01-15 DE DE69921611T patent/DE69921611T2/de not_active Expired - Lifetime
- 1999-01-15 WO PCT/DK1999/000021 patent/WO1999036431A1/en active IP Right Grant
- 1999-01-15 EP EP04078016A patent/EP1506969B1/en not_active Expired - Lifetime
- 1999-01-15 JP JP2000540146A patent/JP4382279B2/ja not_active Expired - Lifetime
- 1999-01-15 HU HU0100777A patent/HUP0100777A3/hu unknown
- 1999-01-15 IL IL13700799A patent/IL137007A0/xx unknown
- 1999-01-15 EP EP99900877A patent/EP1047709B1/en not_active Expired - Lifetime
- 1999-01-15 KR KR1020007007835A patent/KR20010034198A/ko not_active Application Discontinuation
- 1999-01-15 CA CA002318558A patent/CA2318558A1/en not_active Abandoned
- 1999-01-15 AT AT04078016T patent/ATE470671T1/de not_active IP Right Cessation
- 1999-01-15 PL PL99341707A patent/PL341707A1/xx not_active Application Discontinuation
- 1999-01-15 AU AU20465/99A patent/AU766305B2/en not_active Ceased
- 1999-01-15 AT AT99900877T patent/ATE281467T1/de not_active IP Right Cessation
- 1999-01-15 CN CN99802165A patent/CN1288467A/zh active Pending
- 1999-01-15 BR BR9906975-0A patent/BR9906975A/pt not_active IP Right Cessation
- 1999-01-26 TW TW088101140A patent/TW589325B/zh active
-
2000
- 2000-07-14 NO NO20003629A patent/NO20003629L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69921611D1 (de) | 2004-12-09 |
| CN1288467A (zh) | 2001-03-21 |
| EP1506969B1 (en) | 2010-06-09 |
| AU766305B2 (en) | 2003-10-16 |
| WO1999036431A9 (en) | 2000-07-27 |
| TW589325B (en) | 2004-06-01 |
| NO20003629D0 (no) | 2000-07-14 |
| EP1047709A1 (en) | 2000-11-02 |
| HUP0100777A3 (en) | 2001-12-28 |
| EP1506969A1 (en) | 2005-02-16 |
| JP4382279B2 (ja) | 2009-12-09 |
| BR9906975A (pt) | 2000-10-17 |
| CA2318558A1 (en) | 1999-07-22 |
| AU2046599A (en) | 1999-08-02 |
| PL341707A1 (en) | 2001-04-23 |
| NO20003629L (no) | 2000-09-15 |
| ATE281467T1 (de) | 2004-11-15 |
| DE69921611T2 (de) | 2005-11-03 |
| EP1047709B1 (en) | 2004-11-03 |
| HUP0100777A2 (hu) | 2001-08-28 |
| KR20010034198A (ko) | 2001-04-25 |
| WO1999036431A1 (en) | 1999-07-22 |
| ATE470671T1 (de) | 2010-06-15 |
| JP2002509156A (ja) | 2002-03-26 |
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