IL136046A0 - Methods for classifying proteins - Google Patents
Methods for classifying proteinsInfo
- Publication number
- IL136046A0 IL136046A0 IL13604698A IL13604698A IL136046A0 IL 136046 A0 IL136046 A0 IL 136046A0 IL 13604698 A IL13604698 A IL 13604698A IL 13604698 A IL13604698 A IL 13604698A IL 136046 A0 IL136046 A0 IL 136046A0
- Authority
- IL
- Israel
- Prior art keywords
- protein
- molecules
- shift
- multiplicity
- unfolding curve
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 10
- 108090000623 proteins and genes Proteins 0.000 title abstract 10
- 238000000034 method Methods 0.000 title abstract 3
- 238000001228 spectrum Methods 0.000 abstract 4
- 239000003446 ligand Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96444—Factor X (3.4.21.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6512997P | 1997-11-12 | 1997-11-12 | |
PCT/US1998/024035 WO1999024050A1 (en) | 1997-11-12 | 1998-11-12 | High throughput method for functionally classifying proteins identified using a genomics approach |
Publications (1)
Publication Number | Publication Date |
---|---|
IL136046A0 true IL136046A0 (en) | 2001-05-20 |
Family
ID=22060528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13604698A IL136046A0 (en) | 1997-11-12 | 1998-11-12 | Methods for classifying proteins |
Country Status (15)
Country | Link |
---|---|
US (2) | US20010003648A1 (ja) |
EP (1) | EP1030678B1 (ja) |
JP (1) | JP2002514571A (ja) |
KR (2) | KR100406310B1 (ja) |
AT (1) | ATE335498T1 (ja) |
AU (1) | AU750501B2 (ja) |
CA (1) | CA2309345C (ja) |
DE (1) | DE69835531T2 (ja) |
DK (1) | DK1030678T3 (ja) |
ES (1) | ES2273442T3 (ja) |
HU (1) | HU225767B1 (ja) |
IL (1) | IL136046A0 (ja) |
NZ (1) | NZ504483A (ja) |
PL (1) | PL194483B1 (ja) |
WO (1) | WO1999024050A1 (ja) |
Families Citing this family (28)
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US6337183B1 (en) * | 1995-09-08 | 2002-01-08 | Scriptgen Pharmaceuticals, Inc. | Screen for compounds with affinity for nucleic acids |
JP2002514571A (ja) | 1997-11-12 | 2002-05-21 | 3−ディメンショナル ファーマシューティカルズ, インコーポレイテッド | ゲノムアプローチを使用して同定されるタンパク質を機能的に分類するためのハイスループット方法 |
US6569631B1 (en) * | 1998-11-12 | 2003-05-27 | 3-Dimensional Pharmaceuticals, Inc. | Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes |
EP1409982A4 (en) * | 2001-06-14 | 2006-05-24 | Anadys Pharmaceuticals Inc | PROCESS FOR SCREENING ON LIGANDS OF TARGET MOLECULES |
AU2002325030A1 (en) * | 2001-09-18 | 2003-04-01 | Energetic Geonomics Corporation | A high throughput energy array |
US20030170810A1 (en) * | 2001-09-18 | 2003-09-11 | Masoud Vedadi | Methods and apparatuses for purification |
GB0125436D0 (en) * | 2001-10-23 | 2001-12-12 | Deltadot Ltd | Analysis of temperature-dependent molecular configurations |
US20040009530A1 (en) * | 2002-01-16 | 2004-01-15 | Wilson David S. | Engineered binding proteins |
EP1470241A2 (en) * | 2002-01-24 | 2004-10-27 | Ecopia Biosciences Inc. | Method, system and knowledge repository for identifying a secondary metabolite from a microorganism |
AU2003247276A1 (en) * | 2002-02-20 | 2003-09-09 | Affinium Pharmaceuticals, Inc. | Methods and apparatuses for characterizing stability of biological molecules |
US20050079526A1 (en) * | 2002-02-20 | 2005-04-14 | Affinium Pharmaceuticals, Inc. | Methods and apparatuses for characterizing refolding and aggregation of biological molecules |
US20040033530A1 (en) * | 2002-04-08 | 2004-02-19 | Awrey Donald E. | High throughput purification, characterization and identification of recombinant proteins |
US20040121445A1 (en) * | 2002-07-31 | 2004-06-24 | Fabien Marino | Cell cultures |
DE102004017039A1 (de) * | 2004-04-02 | 2005-11-03 | Rwth Aachen | Verfahren und Vorrichtung zur Erfassung von Prozessparametern von Reaktionsflüssigkeiten in mehreren geschüttelten Mikroreaktoren |
US8145433B2 (en) * | 2007-10-25 | 2012-03-27 | Canon U.S. Life Sciences, Inc. | High-resolution melting analysis |
US8993714B2 (en) * | 2007-10-26 | 2015-03-31 | Imiplex Llc | Streptavidin macromolecular adaptor and complexes thereof |
US9102526B2 (en) | 2008-08-12 | 2015-08-11 | Imiplex Llc | Node polypeptides for nanostructure assembly |
WO2010109204A1 (en) * | 2009-03-26 | 2010-09-30 | Ucb Pharma S.A. | Thermofluor method |
US9285363B2 (en) | 2009-05-11 | 2016-03-15 | Imiplex Llc | Method of protein nanostructure fabrication |
GB201106548D0 (en) * | 2011-04-18 | 2011-06-01 | Evitraproteoma Ab | A method for determining ligand binding to a target protein using a thermal shift assahy |
US9523693B2 (en) | 2011-04-18 | 2016-12-20 | Biotarget Engagement Interest Group Ab | Methods for determining ligand binding to a target protein using a thermal shift assay |
EP2753927B1 (en) * | 2011-09-06 | 2017-11-15 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Methods for analyzing biological macromolecular complexes and use thereof |
EP2807489B1 (en) | 2012-01-27 | 2018-10-03 | Life Technologies Corporation | Systems and methods for protein melt analysis using dipyrrometheneboron difluoride compounds |
US10024863B2 (en) | 2013-03-15 | 2018-07-17 | Life Technologies Corporation | Methods for dye selection for protein melt temperature determinations |
GB2524519B (en) * | 2014-03-25 | 2019-11-06 | Pelago Bioscience AB | Methods for identifying a biomarker indicative of a reduced drug response using a thermal shift assay |
US11027273B2 (en) * | 2015-03-01 | 2021-06-08 | Board Of Regents, The University Of Texas System | Apparatuses and methods for pathogen detection using microfluidic biochips |
WO2017053567A1 (en) * | 2015-09-22 | 2017-03-30 | Delta Tm Technologies | Designing customized protein-specific buffer systems |
US11466309B2 (en) | 2018-10-12 | 2022-10-11 | The Board Of Trustees Of The University Of Arkansas | Mechanically-strained oligonucleotide constructs and methods of using the same |
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CA2184195C (en) | 1995-10-25 | 2002-04-16 | Andrew Pakula | Screening method for identifying ligands for target proteins |
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JP2000511629A (ja) | 1996-05-09 | 2000-09-05 | 3―ディメンショナル ファーマシュウティカルズ,インコーポレイテッド | リガンドの開発および多変量タンパク質化学最適化のためのマイクロプレート熱シフトアッセイおよび装置 |
EP0934515B1 (en) | 1996-10-09 | 2006-03-08 | Symyx Technologies, Inc. | Infrared spectroscopy and imaging of libraries |
WO1998039484A1 (en) | 1997-03-05 | 1998-09-11 | Scriptgen Pharmaceuticals, Inc. | Screen employing fluorescence anisotropy to identify compounds with affinity for nucleic acids |
JP2002514571A (ja) | 1997-11-12 | 2002-05-21 | 3−ディメンショナル ファーマシューティカルズ, インコーポレイテッド | ゲノムアプローチを使用して同定されるタンパク質を機能的に分類するためのハイスループット方法 |
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-
1998
- 1998-11-12 JP JP2000520138A patent/JP2002514571A/ja active Pending
- 1998-11-12 ES ES98957812T patent/ES2273442T3/es not_active Expired - Lifetime
- 1998-11-12 PL PL98340449A patent/PL194483B1/pl unknown
- 1998-11-12 DE DE69835531T patent/DE69835531T2/de not_active Expired - Lifetime
- 1998-11-12 HU HU0100037A patent/HU225767B1/hu unknown
- 1998-11-12 AU AU13980/99A patent/AU750501B2/en not_active Expired
- 1998-11-12 CA CA002309345A patent/CA2309345C/en not_active Expired - Lifetime
- 1998-11-12 AT AT98957812T patent/ATE335498T1/de not_active IP Right Cessation
- 1998-11-12 DK DK98957812T patent/DK1030678T3/da active
- 1998-11-12 EP EP98957812A patent/EP1030678B1/en not_active Expired - Lifetime
- 1998-11-12 IL IL13604698A patent/IL136046A0/xx unknown
- 1998-11-12 KR KR10-2000-7005169A patent/KR100406310B1/ko not_active IP Right Cessation
- 1998-11-12 WO PCT/US1998/024035 patent/WO1999024050A1/en active IP Right Grant
- 1998-11-12 US US09/190,128 patent/US20010003648A1/en not_active Abandoned
- 1998-11-12 KR KR10-2003-7002857A patent/KR20030040425A/ko not_active Application Discontinuation
- 1998-11-12 NZ NZ504483A patent/NZ504483A/xx not_active IP Right Cessation
-
2002
- 2002-01-29 US US10/057,940 patent/US7122321B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NZ504483A (en) | 2002-11-26 |
US20010003648A1 (en) | 2001-06-14 |
JP2002514571A (ja) | 2002-05-21 |
PL194483B1 (pl) | 2007-06-29 |
WO1999024050A9 (en) | 1999-08-12 |
DE69835531T2 (de) | 2007-04-05 |
HU225767B1 (en) | 2007-08-28 |
CA2309345C (en) | 2007-01-23 |
DE69835531D1 (de) | 2006-09-21 |
EP1030678A4 (en) | 2002-10-09 |
PL340449A1 (en) | 2001-02-12 |
AU750501B2 (en) | 2002-07-18 |
KR20010032048A (ko) | 2001-04-16 |
EP1030678B1 (en) | 2006-08-09 |
ATE335498T1 (de) | 2006-09-15 |
HUP0100037A2 (hu) | 2001-05-28 |
HUP0100037A3 (en) | 2003-08-28 |
WO1999024050A1 (en) | 1999-05-20 |
AU1398099A (en) | 1999-05-31 |
US7122321B2 (en) | 2006-10-17 |
KR100406310B1 (ko) | 2003-11-19 |
EP1030678A1 (en) | 2000-08-30 |
US20020168686A1 (en) | 2002-11-14 |
ES2273442T3 (es) | 2007-05-01 |
DK1030678T3 (da) | 2006-12-11 |
KR20030040425A (ko) | 2003-05-22 |
CA2309345A1 (en) | 1999-05-20 |
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